scholarly journals Review of Chemical Properties and Ethnomedicinal uses of Acanthosicyos horridus Welw. ex Hook. f.: An Indigenous Melon Species of South-West Coast of Africa -

2020 ◽  
Vol 10 (5) ◽  
pp. 274-279
Author(s):  
Alfred Maroyi

Acanthosicyos horridus Welw. ex Hook. f. is a perennial shrub collected from the wild for its edible fruits and is also used as a traditional medicine. This study is aimed at evaluating the chemical properties and ethnomedicinal uses of A. horridus. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. This study revealed that the fruit and root infusions and/or decoctions of A. horridus are used as traditional medicine for arteriosclerosis, chest pains, gastro-intestinal disorders, kidney problems, nausea and sexually transmitted infections. Phytochemical compounds identified from the species include cucurbitacins, fatty acids and sterols. Some of the compounds identified from the species have applications in food industry and health promoting products.

2020 ◽  
Vol 10 (5) ◽  
pp. 190-195
Author(s):  
Alfred Maroyi

Cladostemon kirkii (Oliv.) Pax & Gilg is a shrub or a small tree widely used as traditional medicine in tropical Africa. This study is aimed at evaluating the chemical properties, biological activities and ethnomedicinal uses of C. kirkii. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The articles published between 1960 and 2019 were used in this study. This study revealed that the bark, leaf, root and stem infusion and/or decoction of C. kirkii are mainly used as traditional medicines for boils, colds, gastro-intestinal problems, hypertension, ophthalmia, rheumatism, sexual dysfunction, abdominal pains, sexually transmitted infections, sores and wounds. Phytochemical compounds identified from the species include mearnsitrin, myricitrin, kaempferol-5-rhamnoside, kaempferin, kaempferol 3-gluco-7-rhamnoside, quercetin 3,7-dirhamnoside, quercetin 3-gluco-7-rhamnoside, choline, 3-hydroxyprolinebetaine and tetramethylammonium. Cladostemon kirkii should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.


2020 ◽  
Vol 10 (5) ◽  
pp. 247-256
Author(s):  
Alfred Maroyi

Maerua angolensis DC. is collected from the wild for its edible leaves and fruits, and is also used as a traditional medicine. This study is aimed at evaluating the ethnomedicinal uses, phytochemistry and pharmacological properties of M. angolensis. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The articles published between 1960 and 2020 were used in this study. This study revealed that the aerial parts, bark, leaves, roots and stem bark infusion and/or decoction of M. angolensis are mainly used as a protective charm and ethnoveterinary medicine, and a traditional medicine for pain, cancer, fever, malaria, sores, wounds and gastro-intestinal problems. Phytochemical compounds identified from the species include alkaloids, amino acids, anthraquinones, betaines, cardiac glycosides, cyanidin, esters, fatty acids, flavonoids, glucosinolates, phenols, saponins, sterols, steroids, tannins and triperpenoids. Ethnopharmacological research revealed that M. angolensis extracts have acaricidal, anthelmintic, antibacterial, antifungal, antidiarrhoeal, anticonvulsant, anti-diabetic, antidepressant, anti-inflammatory, antioxidant, antinociceptive, anxiolytic, anti-urolithiatic, antiprotozoal, molluscicidal and nematicidal activities. There is need for extensive toxicological evaluations of crude extracts and compounds isolated from the species since M. angolensis contains potentially toxic compounds


2020 ◽  
Vol 11 (4) ◽  
pp. 5089-5096
Author(s):  
Alfred Maroyi

Maerua edulis (Gilg & Gilg-Ben.) DeWolf  is collected from the wild for its edible fruits and also used as traditional medicine. This study is aimed at evaluating the ethnomedicinal uses, phytochemistry and pharmacological properties of M. edulis. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. This study revealed that the bark, fruit, leaf, root and tuber infusion and decoction of M. edulis  are mainly used as a thirst quencher and ethnoveterinary medicine, and traditional medicine for eye infections, stomach ache, infertility in women, wounds, fungal infections, rheumatic swellings, cough and tuberculosis and sexually transmitted diseases. Phytochemical compounds identified from the species include agmatine, betaines, cardiac glycosides, fatty acids, flavonoids and quaternary ammonium compounds. Ethnopharmacological research revealed that M. edulis extracts and compounds isolated from the species have acaricidal, anthelmintic, antibacterial, antimycobacterial, antifungal, antiproliferative and insecticidal activities. Future research on M. edulis should focus on the possible biochemical mechanisms of both the crude extracts and identified phytochemical compounds including toxicological, in vivo and clinical studies to corroborate the traditional medicinal applications of the species.


2020 ◽  
Vol 11 (4) ◽  
pp. 7889-7897
Author(s):  
Alfred Maroyi

Maerua pseudopetalosa (Gilg & Gilg-Ben.) DeWolf  is  a perennial herb or subshrub collected from the wild as a food plant or traditional medicine. Maerua pseudopetalosa occurs naturally from Senegal, east to Eritrea and Ethiopia, through South Sudan, Sudan, East Africa, south to the Democratic Republic of Congo (DRC). This study is aimed at evaluating the chemical properties, biological activities and ethnomedicinal uses of M. pseudopetalosa. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. This study revealed that the fruit, leaf and root infusion and/or decoction of M. pseudopetalosa are mainly used as a stimulant and to restore physical strength and vitality, and traditional medicine for chest pains, breast cancer and cough. Phytochemical compounds identified from aerial parts, fruits, roots, seeds and tubers of M. pseudopetalosa  include quaternary ammonium compounds, alkaloids, amino acids, betaines, cardiac glycosides, fatty acids, essential oils, flavonoids, phenolics, sterols and tannins. Preliminary ethnopharmacological research revealed that aerial parts, roots and tubers of M. pseudopetalosa have antibacterial, antifungal, antihyperglycemic, antioxidant, α-glucosidase inhibitory, pancreatic lipase inhibitory and cytotoxicity activities. Maerua pseudopetalosa should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.


2020 ◽  
Vol 10 (5) ◽  
pp. 196-204
Author(s):  
Alfred Maroyi

Gymnanthemum coloratum is a shrub or a small tree widely used as traditional medicine throughout its distributional range in tropical Africa. The current study is aimed at reviewing the phytochemistry, pharmacological properties and medicinal uses of G. coloratum. Literature on pharmacological properties, phytochemistry and medicinal uses of G. coloratum was obtained from numerous internet sources such as Scopus, Elsevier, SciFinder, Google Scholar, Pubmed, ScienceDirect, BMC and Web of Science. Other sources of information included pre-electronic sources such as journal articles, theses, book chapters, books and other scientific publications obtained from the university library. The articles published between 1964 and 2020 were used in this study. The current study showed that G. coloratum is used as an anthelmintic, and traditional medicine for reproductive problems, schistosomiasis, liver diseases, sexually transmitted infections, diabetes, sores and wounds, respiratory problems, malaria, skin diseases, fever and gastro-intestinal problems. Ethnopharmacological research identified glaucolides, lactones, amino acids, essential oils, alkaloids, anthocyanins, cardenolids, coumarins, flavonoids, glycosides, leucoanthocyanins, phenols, quinones, reducing sugars, saponins, steroids, tannins, terpenoids and triterpenes from the aerial parts, leaves, roots and stems of G. coloratum. The aerial parts, leaves, roots and whole plant parts of G. coloratum and compounds isolated from the species exhibited anthelmintic, antimicrobial, anti-Blastocystis, anti-inflammatory, anti-sickling, insecticidal and larvicidal, antiplasmodial, antimalarial, antioxidant, antiproliferative, anti-Toxoplasma, hypoglycaemic and antidiabetic and cytotoxicity activities. Gymnanthemum coloratum should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


2021 ◽  
Vol 2021 ◽  
pp. 1-19
Author(s):  
Mohammed El Haouari ◽  
Najat Assem ◽  
Sushil Changan ◽  
Manoj Kumar ◽  
Sevgi Durna Daştan ◽  
...  

Arbutus unedo L. (Ericaceae) is an evergreen shrub widely distributed in the Mediterranean region, particularly through the Moroccan forests. It is an important medicinal plant of great scientific interest due to its nutritional, pharmacological, and chemical properties. The objective of this review is to provide insights into traditional medicinal uses and phytochemical and pharmacological properties of A. unedo from Morocco. In Morocco, the plant has been used as a traditional medicine to treat several pathological conditions. Many phytochemical compounds have been reported in the plant, of which vitamins, carotenoids, flavonoids, polyphenols, tannins, and their derivatives are the most prevalent. Leaves and fruits of A. unedo contain the most significant number of phytochemicals among the species. Furthermore, researchers have demonstrated that A. unedo exhibited antioxidant, anticancer, antibacterial, antidiabetic, antiaggregant, and antihypertensive activities due to the presence of many biochemical compounds with health-promoting properties. According to different toxicity tests, the use of A. unedo is devoid of any significant side effects and/or toxicity. Despite its nutraceutical and health-promoting properties, Moroccan A. unedo remains underexploited mainly, and most of its traditional uses have not yet undergone scientific evidence-based research; therefore, improved knowledge about the potential value of the plant would allow understanding of its biological activity based on its phytochemical compounds that may contribute to the species preservation and valorization.


2020 ◽  
Vol 11 (4) ◽  
pp. 6017-6022
Author(s):  
Alfred Maroyi

Maerua juncea Pax and M. schinzii Pax have a long history of medicinal use in southern Africa. This study aimed to review the ethnomedicinal uses, phytochemistry and pharmacological properties of the two species. Results of this study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The leaves, roots, stems or whole plant parts of M. juncea and M. schinzii are mainly used as protective charm and tonic, and traditional medicines for fever, heart problems, headache, earache, skin disorders, fatigue and respiratory problems. This study showed that betaines and quaternary ammonium compounds such as 3-hydroxyprolinebetaine, proline betaine and 3-hydroxy-1,1-dimethyl pyrrolidinium had been identified from the aerial parts of M. juncea. In contrast, alkaloids, bitter principles, coumarins, flavonoids, saponins and terpenes have been identified from the leaves of M. schinzii. The leaf extracts and compounds isolated from the species exhibited antibacterial, antifungal, anti-HIV and cytotoxicity activities. There is a need for extensive phytochemical, pharmacological and toxicological studies of crude extracts of M. juncea and M. schinzii to establish the safety profiles of different preparations of the two species.


2020 ◽  
Vol 10 (5) ◽  
pp. 230-238
Author(s):  
Alfred Maroyi

Baccharoides adoensis is a shrub widely used as traditional medicine throughout its distributional range in tropical Africa. This study is aimed at providing a critical review of the pharmacological properties, phytochemistry, and medicinal uses of B. adoensis. Documented information on the pharmacological properties, phytochemistry, and medicinal uses of B. adoensis was collected from several online sources which included Scopus, Google Scholar, PubMed and Science Direct. Additional information on the pharmacological properties, phytochemistry, and medicinal uses of B. adoensis was gathered from pre-electronic sources such as book chapters, books, journal articles, and scientific publications sourced from the university library. The articles published between 1962 and 2020 were used in this study. This study showed that the roots, flowers, stems, and leaves of B adoensis are widely used as ethnoveterinary medicine and traditional medicines for backbone pain, reproductive problems, kidney diseases, fever and febrile complaints, wounds, ulcers, sexually transmitted infections, skin complaints, malaria, gastro-intestinal problems and respiratory problems. Phytochemical compounds identified from the species include alkaloids, carbohydrates, chondrillasterol, flavonoids, free sugars, glaucolides, glycosides, phenols, proanthocyanidin, saponins, steroids, tannins and terpenoids. Pharmacological research revealed that B. adoensis extracts and compounds isolated from the species have antimicrobial, antimycobacterial, anti-inflammatory, antioxidant, antiplasmodial, anti-pyretic, antitrypanosomal, antileishmanial, anti-ulcer and gastroprotective, immunomodulating, inhibition of Helicobacter pylori adhesion, larvicidal, cytotoxicity and toxicity activities. Baccharoides adoensis should be subjected to detailed phytochemical, pharmacological, and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


Author(s):  
Alfred Maroyi

Dicoma anomala is used as herbal medicine to treat and manage fever, coughs, colds, sore throats, abdominal pain, diarrhea, dysentery, constipation, intestinal worms, and sexually transmitted infections in tropical Africa. The aim of this study was to summarize the research that has been done on the ethnomedicinal uses, phytochemistry, and pharmacological properties of D. anomala in tropical Africa. The literature search for information on ethnomedicinal uses and pharmacological activities of D. anomala was undertaken using databases such as Web of Science, Scopus, Google Scholar, Science Direct, BioMed Central, PubMed, and Springer link. Other relevant literature sources included books, book chapters, websites, theses, conference papers, and other scientific publications. This study showed that D. anomala is used as herbal medicine in 57.1% of the countries in tropical Africa where it is indigenous. The species is used to treat 66 and five human and animal diseases, respectively. Several classes of secondary metabolites including acetylenic compounds, diterpene, flavonoids, phenols, phytosterols, saponins, sesquiterpenes, tannins and triterpenes have been isolated from D. anomala. Different aqueous and organic extracts of D. anomala exhibited anthelmintic, anticancer, antihyperglycemic, anti-inflammatory, antimicrobial, antioxidant, antiplasmodial, and hepatoprotective activities. The documented information on the botany, ethnomedicinal uses, phytochemistry, and pharmacological properties of D. anomala provide baseline data required for further ethnopharmacological studies on the species.


2020 ◽  
Vol 11 (4) ◽  
pp. 5460-5466
Author(s):  
Alfred Maroyi

Schefflera umbellifera (Sond.) Baill. is an evergreen tree widely used as traditional medicine throughout its distributional range in southern Africa. Schefflera umbellifera is indigenous to Eswatini, Malawi, Mozambique, South Africa and Zimbabwe. This study was aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of S. umbellifera. Documented information on medicinal uses, phytochemical and pharmacological properties of S. umbellifera was collected from several online sources such as Scopus, Google Scholar, PubMed, Francis and Taylor and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the University library. This study revealed that the bark, leaf and root decoction or infusion of S. umbellifera are mainly used as diuretic, laxative, colic and protective charm, and traditional medicine for stomach ulcers, weaning infants, insanity, inflammation, rheumatism and malaria. Phytochemical compounds identified from the species include 3-hydroxy-20(29)-lupen-28-ol, 7-hydroxy-6-methoxycoumarin, betulin, ent-kaur-16-en-19-oic acid and oleanolic acid. Pharmacological research revealed that S. umbellifera extracts and compounds isolated from the species have antibacterial, anti-HIV, anti-inflammatory, antimalarial, antiprotozoal, larvicidal and cytotoxicity activities. Schefflera umbellifera should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


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