scholarly journals CHRONIC KIDNEY DISEASE

2018 ◽  
Vol 25 (03) ◽  
pp. 392-395
Author(s):  
Irfan Elahi ◽  
Zeshan Nasir ◽  
Sajjad Ahmed ◽  
Shamsa Raheel
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Bright Light ◽  
Demographic Information ◽  
Age And Gender ◽  
Nail Changes ◽  
Study Methodology ◽  
And Gender ◽  
Hands And Feet ◽  
Structured Questionnaire

Objectives: The objective of the study was to find out the prevalence of typesof nail changes in chronic kidney disease. Settings: Nephrology department, Mayo HospitalLahore. Duration of Study: From July 2016 to March 2017. Study Design: Descriptive Crosssectional study. Methodology: A structured questionnaire was filled for data collection. 220CKD patients were recruited. Basic demographic information like age and gender was obtainedfrom cases. Examination of nails of both hands and feet was done under bright light and anyabnormalities were noted on the structured performa. Nail changes were recorded as peroperational definition. Results: In our study, out of 220 cases, 61.36% (n=135) cases werebetween 15-50 years of age while 38.64% (n=85) were between 51-85 years of age, mean+sdwas calculated as 48.11+8.11 years, 57.27% (n=126) were male and 42.73% (n=94) werefemales, 16.36% (n=36) had half and half nails, 21.82% (n=48) had Koilonychia, 2.73% (n=6)had Beau’s lines, 48.64% (n=107) had Absent lanula, 1.36%(n=3) had Leuconychia, 5% (n=11)had Pitting, 1.82% (n=4) had Onycholysis, 2.27% (n=5) had Onychomycosis. Conclusion: Weconcluded that the frequency of nail changes in chronic kidney disease is significantly higherwhile absent lanula is a leading nail disorder followed by koilonychias and half and half nails inthese cases. Some other trials are required to validate our findings.

Age- and Gender-Dependent Correlations between Body Composition and Chronic Kidney Disease

2010 ◽  
Vol 31 (1) ◽  
pp. 83-89 ◽  
Author(s):  
Seung Seok Han ◽  
Nam Ju Heo ◽  
Ki Young Na ◽  
Dong-Wan Chae ◽  
Yon Su Kim ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Body Composition ◽  
Kidney Disease ◽  
Age And Gender ◽  
And Gender

scholarly journals COMPARISON OF BODY COMPOSITION ACCORDING TO AGE AND GENDER IN PATIENTS WITH CHRONIC KIDNEY DISEASE (CKD).

2012 ◽  
Vol 31 (2) ◽  
pp. A70
Author(s):  
Aleksandra Rymarz ◽  
Katarzyna Szamotulska ◽  
Małgorzata Gomółka ◽  
Stanisław Niemczyk
Keyword(s):  
Chronic Kidney Disease ◽  
Body Composition ◽  
Kidney Disease ◽  
Age And Gender ◽  
And Gender

Association between Chronic Kidney Disease and Risk of Cataract: A Nationwide Retrospective Cohort Study

2017 ◽  
Vol 45 (6) ◽  
pp. 524-531 ◽  
Author(s):  
Yin-Tzu Liu ◽  
Tzu-Yao Hung ◽  
Yi-Kung Lee ◽  
Ming-Yuan Huang ◽  
Chen-Yang Hsu ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Renal Impairment ◽  
Renal Disease ◽  
Subgroup Analysis ◽  
Cox Regression ◽  
Age And Gender ◽  
And Gender ◽  
Stage Renal Disease ◽  
The Relationship

Background: Previous studies have established a relationship between chronic kidney disease (CKD) and cataract, but the relationship between the severity of renal impairment and risk of cataract is uncertain. This study investigates the relationship between the severity of renal disease and cataract in a nationwide sample from Taiwan. Methods: The cohort from 1-million National Health Insurance beneficiaries from Taiwan was retrospectively analyzed. All adult beneficiaries were followed from January 1, 2005 until December 31, 2013, to identify patients who underwent cataract surgeries. On the basis of the ambulatory care records, those diagnosed with CKD (ICD-9-CM code: 585) during the follow-up period were enrolled as CKD patients after careful evaluation. Each patient with CKD was age- and gender-matched with 4 individuals who did not have CKD. Cox regression models were applied to compare the hazard of cataract surgery in individuals with and without CKD. Subgroup analysis was used to compare patients with end-stage renal disease (ESRD) with age- and gender-matched non-CKD individuals. ESRD was defined by CKD patients who need regular renal replacement therapy. The same method was applied to evaluate hazard ratios (HRs). Results: After age and gender matching, there were 11,881 patients in the CKD group and 47,524 in the non-CKD group. After control for possible confounding, the adjusted HR (aHR) of cataract was 1.84 (95% CI 1.73-1.95) for the CKD group. Subgroup analysis of patients with ESRD (n = 3,209) and non-CKD individuals (n = 12,836), with matching done on the basis of age and gender, indicated an aHR of cataract was 2.33 (95% CI 2.10-2.59) for the ESRD group. Conclusions: This study indicates a relationship between CKD and cataract, and suggests that the risk for cataract increases with the severity of renal impairment.

scholarly journals A message of the majority with scientific evidence encourages young people to show their prosocial nature in COVID-19 vaccination

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Toshiko Tanaka ◽  
Tsuyoshi Nihonsugi ◽  
Fumio Ohtake ◽  
Masahiko Haruno
Keyword(s):  
Young People ◽  
Online Survey ◽  
Scientific Evidence ◽  
Herd Immunity ◽  
Demographic Information ◽  
Japanese People ◽  
Age And Gender ◽  
Self Interest ◽  
And Gender ◽  
Positive Effect

AbstractThe most promising way to prevent the explosive spread of COVID-19 infection is to achieve herd immunity through vaccination. It is therefore important to motivate those who are less willing to be vaccinated. To address this issue, we conducted an online survey of 6232 Japanese people to investigate age- and gender-dependent differences in attitudes towards COVID-19 vaccination and the underlying psychological processes. We asked participants to read one of nine different messages about COVID-19 vaccination and rate their willingness to be vaccinated. We also collected their 17 social personality trait scores and demographic information. We found that males 10–20 years old were least willing to be vaccinated. We also found that prosocial traits are the driving force for young people, but the motivation in older people also depends on risk aversion and self-interest. Furthermore, an analysis of 9 different messages demonstrated that for young people (particularly males), the message emphasizing the majority’s intention to vaccinate and scientific evidence for the safety of the vaccination had the strongest positive effect on the willingness to be vaccinated, suggesting that the “majority + scientific evidence” message nudges young people to show their prosocial nature in action.

scholarly journals Expression of Circulating MicroRNAs Linked to Bone Metabolism in Chronic Kidney Disease-Mineral and Bone Disorder

Biomedicines ◽  
2020 ◽  
Vol 8 (12) ◽  
pp. 601
Author(s):  
Maria P. Yavropoulou ◽  
Vasilios Vaios ◽  
Polyzois Makras ◽  
Panagiotis Georgianos ◽  
Anastasios Batas ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Operating Characteristic ◽  
Trabecular Bone Score ◽  
Mineral Density ◽  
Mineral And Bone Disorder ◽  
Circulating Micrornas ◽  
Bone Disorder ◽  
And Gender ◽  
Control Study

The pathophysiology of chronic kidney disease–mineral and bone disorder (CKD-MBD) is complex and multifactorial. Recent studies have identified a link between microRNAs (miRNAs) and bone loss. In this study, we investigated the expression of miRNAs in CKD-MBD. In this case-control study, we included thirty patients with CKD-MBD (cases) and 30 age- and gender-matched healthy individuals (controls). Bone mineral density (BMD) and trabecular bone score (TBS) evaluation was performed with dual X-ray absorptiometry. The selected panel of miRNAs included: hsa-miRNA-21-5p; hsa-miRNA-23a-3p; hsa-miRNA-24-2-5p; hsa-miRNA-26a-5p; hsa-miRNA-29a-3; hsa-miRNA-124-3p; hsa-miRNA-2861. The majority of cases had low BMD values. The relative expression of miRNA-21-5p was 15 times lower [fold regulation (FR): −14.7 ± 8.1, p = 0.034), miRNA-124-3p, 6 times lower (FR: −5.9 ± 4, p = 0.005), and miRNA-23a-3p, 4 times lower (FR: −3.8 ± 2.0, p = 0.036) in cases compared to controls. MiRNA-23a-3p was significantly and inversely correlated with TBS, adjusted for calcium metabolism and BMD values (beta = −0.221, p = 0.003, 95% CI −0.360, −0,081) in cases. In a receiver operating characteristic (ROC) analysis, expression of miRNA-124-3p demonstrated 78% sensitivity and 83% specificity in identifying CKD patents with osteoporosis. Serum expression of miRNAs related to osteoblasts (miRNA-23a-3p) and osteoclasts (miRNA-21-5p, miRNA-124-3p) is significantly altered in patients with CKD-MBD.

Cutaneous and nail changes in patients of chronic kidney disease: Observations in a tertiary care unit from S outh I ndia

2013 ◽  
Vol 17 (3) ◽  
pp. 468-470 ◽  
Author(s):  
Sridevi Koduru ◽  
Nagaraju Delhi ◽  
Sriram Naveen Parvathina ◽  
Vishnubhotla Siva Kumar
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Tertiary Care ◽  
Nail Changes

scholarly journals Screening of family members of chronic kidney disease patients with Fabry disease mutations: a very important and underrated task

2020 ◽  
Author(s):  
Luciana Senra de Souza Sodré ◽  
Rosália Maria Nunes Henriques Huaira ◽  
Fernando Antônio Basile Colugnati ◽  
Moises Carminatti ◽  
Luciane Senra de Souza Braga ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Fabry Disease ◽  
Periodic Fever ◽  
Family Members ◽  
Signs And Symptoms ◽  
Cerebrovascular Diseases ◽  
Systemic Hypertension ◽  
Cross Sectional ◽  
Hands And Feet

ABSTRACT Introduction: Fabry disease is a chronic, progressive, and multi-system hereditary condition, related to an Xq22 mutation in X chromosome, which results in deficiency of alpha-galactosidase enzyme, hence reduced capacity of globotriaosylceramide degradation. Objectives: to evaluate the prevalence of Fabry disease (FD) mutations, as well as its signs and symptoms, among relatives of chronic kidney disease (CKD) patients diagnosed with FD during a previously conducted study, named “Clinical and epidemiological analysis of Fabry disease in dialysis centers in Brazil”. Methods: a cross-sectional study was carried out, and data was collected by interviewing the relatives of patients enrolled in the Brazil Fabry Kidney Project and blood tests for both Gb3 dosage and genetic testing. Results: Among 1214 interviewed relatives, 115 (9.47%) were diagnosed with FD, with a predominance of women (66.10%). The most prevalent comorbidities were rheumatologic conditions and systemic hypertension (1.7% each), followed by heart, neurological, cerebrovascular diseases, and depression in 0.9% of individuals. Intolerance to physical exercise and tiredness were the most observed symptoms (1.7%), followed by periodic fever, intolerance to heat or cold, diffuse pain, burn sensation or numbness in hands and feet, reduced or absent sweating, as well as abdominal pain after meals in 0.9%. Conclusion: We found a prevalence of Fabry disease in 9.47% of relatives of CKD patients with this condition, remarkably with a 66.1% predominance of women, which contrasts with previous reports. The screening of family members of FD patients is important, since it can lead to early diagnosis and treatment, thus allowing better quality of life and improved clinical outcomes for these individuals.

Willingness to pay for improved water supplies in rural Ugandan villages

2014 ◽  
Vol 4 (3) ◽  
pp. 490-498 ◽  
Author(s):  
Steven G. Wright ◽  
Daya Muralidharan ◽  
Alex S. Mayer ◽  
William S. Breffle
Keyword(s):  
Willingness To Pay ◽  
Contingent Valuation Method ◽  
Probit Model ◽  
Water Source ◽  
Demographic Information ◽  
Age And Gender ◽  
Number Of Children ◽  
Valuation Method ◽  
And Gender ◽  
Bidding Process

The contingent valuation method was used to estimate willingness to pay (WTP) for the operation and maintenance of an improved water source in the villages of Kigisu and Rubona in rural Uganda. The survey was conducted in August 2011 and administered to 122 households out of 400 in the community, gathering demographic information, health and water behaviors, and using an iterative bidding process to estimate WTP per 20 L for a public tap. The data were analyzed using an ordered probit model, which predicts monetary intervals for households' WTP. The model predicts a mean WTP of 356 Ugandan shillings (USD 0.183) per 20 L from a public tap. It was determined that the number of children in the home and the distance from the existing source are significant in influencing household's WTP, while income, age, and gender are not.

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