scholarly journals ACUTE HEART FAILURE

2018 ◽  
Vol 25 (09) ◽  
pp. 1392-1396
Author(s):  
Jasia Reham Din ◽  
Shahid Maqbool ◽  
Shakeel ur Rehman ◽  
Naeem Hameed

Objectives: To determine the frequency of the major precipitating factorsamong the patients presenting with acute heart failure. Study Design: Cross sectional study.Setting: Faisalabad Institute of Cardiology, Faisalabad. Period: July 2014 to January 2015.Materials and Methods: 190 patients of acute heart failure were included after obtaininginformed consent from emergency department. Patients from age of 25 years to 80 years andof either sex either diabetic or non-diabetic were enrolled in study. ECG and CXR were takenin emergency with baseline investigations. Precipitating cause was identified from collectedhistory, clinical examination and ECG, CXR and lab results. Results: Mean age of these patientswere 54.4 + 8.92, 100 (52.6%) were male, 90 (47.4%) were females, 88 patients (46.3%) werediabetic, 102 patients (53.68%) were non-diabetic and 124 (65.3%) had previous history of heartfailure and 66 (34.7%) had no past history of heart failure. ACS was the common precipitatingfactor of Acute Heart Failure ( 31.57% ) among all the patients of the study with non-complianceof drugs 27.9% , arrhythmias 17.9% uncontrolled hypertension 17.36% and infections 5.3%.Conclusion: Young, male, diabetics and patients with history of chronic HF suffered more fromAHF. ACS was the most common precipitating factor while in patients with de novo Acute HeartFailure; it was ACS and non-compliance with drugs.

2016 ◽  
Vol 23 (10) ◽  
pp. 1281-1287
Author(s):  
Naeem Asghar ◽  
Shakeel Ahmad ◽  
Muhammad Nazim ◽  
Hafiz Muhammad Faiq Ilyas ◽  
Muhammad Nouman Ahmad

Objectives: The objective of the study is to identify the precipitating factorsamong the patients presenting with AHF (Acute Heart Failure). Study Design: Cross sectionalstudy. Setting: Punjab Institute of Cardiology, Lahore. Duration of Study: 6 months. From01-01-2007 to 30-06-2007. Methodology: The calculated sample size was 170 cases with 5%margin of error, 95% confidence level taking expected percentage of uncontrolled hypertensioni.e. 12% (least percentage among all precipitating factors). Results: In the study group, mostlypatients of AHF were young with mean age of 55 + 6.99 years, male (61.8%), Diabetic (53.5%)and have history of chronic Heart Failure (63.5%). In male the most common precipitating factorof AHF was ACS (39.04%) while in female uncontrolled hypertension (38.46%). Conclusion:In diabetic patients the most common precipitating factor of AHF was ACS (30.7%). In patientswith acute decompensation of chronic heart failure the most common precipitating factor wasnon-compliance of medication (30.55%) while in patients with de novo Acute Heart Failure itwas ACS (41.93%). ACS was the common precipitating factor of Acute Heart Failure (28.2%)among the study group irrespective of gender, diabetes and history of Heart Failure.


Author(s):  
Dimitrios Farmakis ◽  
Gerasimos Filippatos

Acute heart failure (AHF) is defined as the rapid development or change of symptoms and signs of heart failure that requires urgent medical attention and usually hospitalization. it represents the first reason for hospital admission in individuals aged 65 or more and accounts for nearly 70% of the total healthcare expenditure for heart failure. It is generally characterized by adverse prognosis, with an in-hospital mortality rate of 4-7%, a 2 to 3-month post-discharge mortality of 7-11% and a 2 to 3-month readmission rate of 25-30%. The majority of patients have a previous history of heart failure and present with symptoms and/or signs of congestion and normal or increased blood pressure, while about half of them have preserved left ventricular ejection fraction. A high prevalence of cardiovascular or non-cardiovascular comorbidities is further observed, including coronary artery disease, arterial hypertension, atrial fibrillation, diabetes mellitus, renal dysfunction, chronic lung disease, anemia and iron deficiency. Different classification criteria have been proposed for AHF, reflecting the clinical heterogeneity of the syndrome. Classifications according to the past history of heart failure (acutely decompensated chronic or de novo), the systolic blood pressure upon presentation (hypertensive, normotensive or hypotensive) and the presence or absence of congestion and peripheral hypoperfusion are among the most widely used. The pathophysiology of AHF involves several mechanisms, including volume overload, pressure overload, myocardial loss and restrictive filling, while several cardiovascular and non-cardiovascular precipitating factors lead to AHF. Regardless of the underlying mechanism, peripheral and/or pulmonary congestion is present in the vast majority of AHF, resulting from fluid retention and/or fluid redistribution, while a marked reduction in cardiac output with peripheral hypoperfusion occurs in a minority of cases. Myocardial injury and renal dysfunction are important factor involved in the precipitation and progression of the syndrome.


Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Mohammed A Al Hashemi ◽  
Kadhim Sulaiman ◽  
Jassim Al-Suwaidi ◽  
Khalid F AlHabib ◽  
Husam AlFaleh ◽  
...  

Background: Chronic heart failure (CHF) is a known risk for stroke and morbidities and mortalities are known to be higher in CHF patients compared to stroke patients without CHF we here study the prevalence and the clinical significance in a group of patient with stroke or transient ischemic attack (TIA) who were admitted to hospital with acute heart failure (AHF) compared to those without stroke and are admitted with acute heart failure Methods: Data were derived from a prospective, multicenter, multinational study of 5005 patients hospitalized with AHF from February 2013 to November 2012. Data were analyzed according to the presence or absence of Stroke or bronchial TIA. Demographic, management, in-hospital and 1-year outcomes were compared Results: Stroke patients were likely to have a decompensation of chronic failure rather than De-Novo AHF when compared to those without Stroke/TIA (see table). Stroke patients were older; more likely to be female, have history of DM, HTN, dyslipidemia and CKD. Stroke patients were likely to have Atrial fibrillation, PVD, systolic LV dysfunction as well as CAD when compared to those without Stroke, they were also more likely receive NIV, IV inotropes and likely to have had cardiac PCI prior to this admission with AHF. Stroke patients had higher recurrence of stroke and one-year mortality rates. Conclusion: Patients who presented with AHF and history of stroke/TIA were having different clinical characteristics as well as comorbidities as compared to those without Stroke, with worse in-hospital and one-year outcome. The current study underlies the need to aggressively manage these high-risk patients.


Author(s):  
João Santos ◽  
Inês Almeida ◽  
Inês Pires ◽  
Filipe Blanco

Abstract Background Muscular dystrophies are characterized by early onset muscular atrophy and weakness, with frequent cardiac involvement. Myocardial dysfunction and conduction system involvement are often rapidly progressive despite medical and device therapy, and may even precede muscular symptoms, posing a challenge to diagnosis. Case summary We report a case of a young male admitted to a cardiac intensive care unit due to “de novo” acute heart failure and atrial flutter with a slow ventricular response. Careful evaluation of past medical history revealed presence of neuromuscular symptoms since childhood, disregarded throughout adult age. Diagnostic workup allowed to establish a diagnosis of non-dilated hypokinetic cardiomyopathy secondary to Emery-Dreifuss muscular dystrophy, due to Lamin A/C gene mutation. Our patient was treated with neurohormonal modulation therapy and a CRT-D was implanted, but due to worsening advanced heart failure, cardiac transplantation was needed. Discussion Association of skeletal muscle and cardiac symptoms should always raise the suspicion for an underlying muscular dystrophy, since the consequences of a missed diagnosis are often dramatic. A timely diagnosis is crucial to prevent sudden death due to arrythmias in these patients and to delay the progressive course of cardiomyopathy.


2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Gidey Gomera Weleslassie ◽  
Hagazi Gebre Meles ◽  
Tsiwaye Gebreyesus Haile ◽  
Gebreslassie Kahsay Hagos

Abstract Background Neck pain is the major cause of morbidity and absenteeism from university lessons among medical students worldwide. Medical students are more exposed and appear to have neck pain because of their length of study to achieve their professional goals. However, up to the knowledge of the researcher, there is a scarcity of literature conducted on prevalence and associated factors of neck pain among medical students in Ethiopia. Therefore, the aim of this study was to determine the prevalence and factors associated with neck pain among medical students at Mekelle University, College of Health Sciences, Tigray, Ethiopia. Method Institutional based cross-sectional study was conducted from April 2018 to May 2018. A structured questionnaire adapted from the Nordic musculoskeletal questionnaire was distributed to 422 participants using a self-administered questionnaire in Mekelle University, College of Health Sciences Tigray, Ethiopia. Independent variables which had a significant association were identified using logistic regression models. Results were reported by using texts and frequency distribution tables. Result A total of 422 participants involved in this study, with a 99.3% response rate. Previous 12 months self-reported prevalence of neck pain among medical students was found to be 49.2% with 95%CI (44.5–54%). Previous history of neck pain (AOR: 11.811, 95%CI: 5.460–25.549), physical exercise (AOR: 2.044, 95%CI: 1.233–3.387), duration of reading (AOR: 1.502, 95%CI: 0.236–2.780) and awkward posture (AOR: 3.87, 95%CI: 2.311–6.484) were factors significantly associated with neck pain. Conclusion and recommendation The current study showed that nearly half of the study participants self-reported to have suffered neck pain in the preceding 12 months. Past history of neck pain, physical exercise, duration of reading and awkward neck posture are likely to be significantly associated neck pain among medical students in Ethiopia. Engaging in consistent physical exercise has a protective effect against neck pain. Therefore, Medical students are recommended to carry out a regular physical exercise for a minimum of twenty to thirty minutes per day.


2020 ◽  
Vol 18 (6) ◽  
pp. 644-651 ◽  
Author(s):  
Charbel Abi Khalil ◽  
Kadhim Sulaiman ◽  
Nidal Asaad ◽  
Khalid F. AlHabib ◽  
Alawi Alsheikh-Ali ◽  
...  

The prognostic impact of beta-blockers (BB) in coronary artery disease (CAD) is controversial, especially in the post-reperfusion era. We studied in-hospital cardiovascular events in patients hospitalized for acute HF, a previous history of CAD and a left ventricular ejection fraction (LVEF) ≥40%, in relation to BB on admission; and 1-year outcome in relation to BB on discharge, in the GULF aCute heArt failuRe (GULF-CARE) registry. From a total of 5005 patients included in the GULF-CARE registry, 303 patients with a previous history of CAD and a LVEF ≥40% on BB were propensity-matched to 303 patients without BB on admission. In-hospital mortality (OR= 0.82; 95% CI [0.35-1.94]), stroke and cardiogenic shock were not reduced by BB. On discharge, 306 patients on BB, including the ones newly diagnosed with myocardial infarction as a precipitating cause of HF, were propensity-scored matched with 306 patients without BB. Mortality (OR= 0.86; 95%CI [0.51-1.45], hospitalization for HF or PCI/CABG at 1 year were also not reduced by BB at discharge. In summary, our data show that BB have a neutral effect on in-hospital and 1-year outcomes in acute heart failure patients with a previous history of CAD and a LVEF ≥40%.


Neurosurgery ◽  
2011 ◽  
Vol 69 (3) ◽  
pp. E761-E767 ◽  
Author(s):  
Nunung Nur Rahmah ◽  
Tetsuyoshi Horiuchi ◽  
Yoshikazu Kusano ◽  
Tetsuo Sasaki ◽  
Kazuhiro Hongo

Abstract BACKGROUND AND IMPORTANCE: Formation of cerebral de novo aneurysms (CDNAs) is rare, and the pathogenesis remains obscure. We analyzed factors involved in formation of CDNAs and suggest guidelines for follow-up of patients. CLINICAL PRESENTATION: We retrospectively reviewed intracranial aneurysms at our institute and published reports from 1964 to 2008. Eleven patients were found with CDNAs, and 138 patients were collected from the published literature. We assessed the clinical characteristics, such as sex, size, and site of CDNA, past history, and time to occurrence of CDNAs. Of 11 patients, 10 were female and 1 was male; the mean age of the first onset was 53 years (range, 25-69 years). The mean time between first aneurysms and CDNAs was 10.6 years (range, 3-29 years). The most common site of occurrence was anterior circulation. One patient experienced contralateral occurrence, and 2 patients changed from anterior to posterior circulation CDNAs. Six (54.5%) patients had a history of arterial hypertension. Results from analysis of the whole series from the literature revealed that the risk of rupture increased with a previous history of hemorrhage. Contralateral occurrence of CDNAs was related to previous location, and multiplicity, whereas the occurrence of anterior to posterior changes of CDNAs and shorter interval only correlated with an older age group. CONCLUSION: Although the formation of CDNAs is rare, several factors may contribute to its occurrence. Female patients with a history of arterial hypertension were at a higher risk for CDNA occurrence. We recommend follow-up imaging studies within 10 years after the initial aneurysms; therefore, at least 50% of CDNAs can be found before rupture.


Author(s):  
Cissy James ◽  
Gopika G. ◽  
Irina Mariya Diju ◽  
Aswathy T. R. ◽  
Karthika J. ◽  
...  

Background: COVID-19 pandemic has completely changed the work pattern of information technology professionals who had to shift from the work from office to work from home pattern. The comforts of home, that they used to enjoy, was now taken up by an office space at home and this has potentially altered the mental health status of these professionals.Methods: A cross sectional study was conducted among IT professionals within the age group 21-45 years working in Kerala. 218 subjects were included in the study. A self-prepared structured questionnaire was used to collect basic demographic information and depression anxiety and stress scale (DASS 21) scale was used to assess depression anxiety and stress among IT professionals using Google form. Informed consent was obtained in the beginning of the questionnaire. The data was entered in Microsoft Excel and analysed using SPSS software.Results: Out of the total study participants 50.5% (110) were males and 49% (108) were females. 42.7% were married and 57.3% were unmarried and none of them were divorced or living separated. Most of the study participants (62.8%) had monthly income below 50,000. Out of the total study participants, 72 (33%) of them were working in IT field for less than 2 years, 52 were working for last 2-4 years, 51 were working for last 4-8 years and only 43 individuals were working for more than 8 years. 67% of them had their working hours raised during COVID lock down. In our study while 21.6% had a previous history of psychiatric illness for which they have consulted a doctor/psychologist. Out of all the study subjects, 4.1% were mildly depressed, 6.9% were moderately depressed, 5.5% were severely depressed and 1.8% had extremely severe depression. Most of the study subjects (81.7%) were not anxious, 9.2% were mildly anxious, 6.8% were moderately anxious, 2.3% were severely anxious. 76.9% had no stress, 6.1% were mildly stressed, 11.5% were moderately stressed, 4.6% were severely stressed and 0.9% had extremely severe stress. Depression among IT professionals during COVID-19 lockdown was found to be significantly associated with past history of psychiatric illness. Anxiety was found to be significantly associated with past history of psychiatric illness and unmarried relationship status. The stress among IT professionals during lockdown was found to be significantly associated with previous history of psychiatric illness and unmarried relationship status.Conclusions: 18.3% of the IT professionals had some degree of depression and 23.1% was facing stress 18.3% was anxious. Past history of psychiatric illness was associated with increased depression anxiety and stress. Unmarried relationship status was associated with associated with increased anxiety and stress.


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