scholarly journals TYPE II DIABETES MELLITUS;

2019 ◽  
Vol 26 (04) ◽  
Author(s):  
Muhammad Mumtaz Ather ◽  
Talha Rasheeq ◽  
Muddasar Ahmed ◽  
Aamir Furqan

Objectives: To determine the frequency of asymptomatic elevation of liver function enzymes in type II diabetes mellitus patients using statins. Study Design: Cross sectional study. Setting and Period: Nishtar Hospital Multan, from February 2017 to February 2018. Material and Methods: A total of 335 patients were enrolled for this study. Sample size was calculated from the reference study.9 Clinical and biographical data was obtained from each patient in the form of previous medical records and patient interview such as, sex, age, height, weight, age at onset of diabetes, family history of diabetes, duration of diabetes, family history of liver diseases, medication history. All the data was measured and recorded by the researcher himself. Data thus obtained was subjected to statistical analysis by using computer software SPSS version 23. Mean and standard deviation was calculated for continuous variables while frequency and percentage was calculated for categorical variables. A p value of less than or equal to 0.05 was taken as significant for univariate test. ANOVA test was utilized to evaluate the relationship ALT and AST and other metabolic parameters. Results: Although the prevalence of elevated ALT increased with the increasing age, duration of diabetes, BMI, FBS and TG, but it was not statistically significant with (p=0.634), (p=0.759), (p=0.844), (p=0.400) and (p=0.246) respectively. Similarly, the prevalence of elevated AST increased with the increasing age, duration of diabetes, BMI, FBS and TG, but it was not statistically significant with (p=0.779), (p=0.945), (p=0.987), (p=0.199) and (p=0.933) respectively. (Table II). Conclusion: From this study it can be concluded that use of statins does not alter the usual finding of elevated liver enzymes among the patients with type two diabetes mellitus.

2019 ◽  
Vol 26 (06) ◽  
Author(s):  
Muslim Khahro ◽  
Qaimuddin Shaikh ◽  
Mehnaz Baloch ◽  
Surwaich Ali Channa ◽  
Arhama Shah

Objectives: To determine the frequency of dental caries in patients with type II diabetes mellitus. Study Design: Cross sectional study. Setting: Dental Department of Science of Dental Materials Department and Oral Pathology Department. Period: 6 months from October 2016 to February 2017. Material and Methods: All the diagnosed patients of type II diabetes mellitus either gender were selected for the study. Complete dental clinical examination and duration of diabetes were carried out. Dental caries were categorized as mild moderate and severe. Duration of diabetes was categorized as < years and > 5 years. All the data was recorded in the self-made proforma. Results: In this study total 58 patients were selected with history of type II diabetes mellitus; patient’s mean age was 46.36+5.34 years. Male gender was found in the majority 38(65.5%). Majority of the cases 37(63.8%) were found with low socioeconomic status. 26(44.8%) patients had history of type II diabetes mellitus less than 5 years, 32(55.2%) were with more than 5 years history of diabetes. 15.51% patients were without dental caries, 37.39% patients were with mild, 34.4% had moderate and 12.06% patients were with severe dental caries. No significant difference was found in severity of dental caries when compared with duration of diabetes p-value 0.93.  Conclusion: We concluded that there are a big prevalence dental caries among patients with type II diabetes mellitus, while severity of dental caries was insignificantly associated with duration of diabetes.


Author(s):  
A.P. Mitha ◽  
J.H. Wong ◽  
S.J. du Plessis

A 51-year-old gentleman of Chinese descent presented for neurological evaluation following a two-year history of cervical neck pain associated with left arm numbness. His symptoms were initially stable, but had progressed over the past six months to include weakness of his entire left arm and leg and symptoms of bladder urgency. Two weeks prior to presentation, he suffered repeated falls due to worsening gait difficulties. The past medical history was significant for type II diabetes mellitus.


2017 ◽  
Vol 3 (1) ◽  
pp. 6-10
Author(s):  
N Bhavya ◽  
V Ajith Kumar

ABSTRACT Introduction India is claimed to be the diabetes capital of the world. Many studies had proven that persistent hyperglycemia and associated metabolic syndrome features like hypertension, dyslipidemia, and obesity contribute to the development of vascular complications. The risk of chronic complications increases as a function of the duration of hyperglycemia; they usually become apparent in the second decade of hyperglycemia. Since type II diabetes mellitus (DM) often has a long asymptomatic period of hyperglycemia, many individuals with type II DM have complications at the time of diagnosis. The vascular complications of DM are subdivided into microvascular (retinopathy, neuropathy, nephropathy) and macrovascular (coronary artery disease, peripheral arterial disease, cerebro-vascular disease) complications. The present study aims to study the occurrence of microalbuminuria in patients with type II DM and note its association with the duration of diabetes since diagnosis and microvascular complications of DM. Study design Prospective observational study. Materials and methods The study is a clinical, prospective, and observational study of 100 type II diabetics attending the medicine department outpatient/inpatient of RajaRajeswari Medical College & Hospital, Bengaluru, Karnataka, India, who form the subjects for the study conducted from August 2015 to July 2016 (12 months) and who matched the inclusion criteria. Data were collected after obtaining informed/written consent from patient. After detailed history, detailed clinical examination, and general physical and systemic examinations, fundoscopy was carried out and relevant laboratory investigations were done. Results and conclusion The overall occurrence of microalbuminuria was 38%. The occurrence of microalbuminuria showed a direct relationship with increasing age (p = 0.053) and increasing duration of diabetes since diagnosis. A hemoglobin (Hb)A1c value above 7% is associated with 50% or higher incidence of microalbuminuria (p = 0.018). Patients with a body mass index of more than 25kg/m2 have increased risk of developing type II DM and significant increase in microalbuminuria. The incidence of microalbuminuria is significantly associated with How to cite this article Bhavya N, Kumar VA. A Study of Association between Microalbuminuria and Microvascular Complications in Type II Diabetes Mellitus Patients in RajaRajeswari Medical College and Hospital, Karnataka. J Med Sci 2017;3(1):6-10.


Ophthalmology ◽  
1997 ◽  
Vol 104 (3) ◽  
pp. 473-478 ◽  
Author(s):  
Taiichi Hikichi ◽  
Naoki Fujio ◽  
Jun Akiba ◽  
Yoshinao Azuma ◽  
Masatoshi Takahashi ◽  
...  

Author(s):  
Dulcie Celia A. ◽  
Ezhil Ramya J. ◽  
Sriviruthi B.

Background: To evaluate the impact of type-II diabetes mellitus on cognitive function and to assess the factors associated with impaired function.Methods: This prospective study compared 100 type-II diabetic people attending the diabetic clinic of Tirunelveli Medical College Hospital with another 100 membered control group. The study group was selected randomly between the age group of 45-65 years. A neuro-cognitive assessment was done using Standardized Mini Mental State Examination (SMMSE), which is a simple and reliable screening test. This scale has 12 questions with time limits to assess orientation, memory, calculation, language, attention and construction. Magnitude and severity of cognitive decrement were analysed along with the possible factors affecting it.Results: Mean age of the study population was 54.6±7.24 years. Cognitive impairment was noted among 62 of cases and 48 of the control group, which means a 14% higher prevalence of cognitive impairment among the type 2 diabetics. The association of development of cognitive impairment and duration of diabetes mellitus was significant statistically (p value = 0.025443; p<0.05). Other demographic variables like gender, education and domicile were also seen to affect the results.Conclusions: Mild to moderate cognitive impairment was found significantly higher among the type-II diabetics than the non-diabetics. The cognitive impairment was found to be associated with the duration of diabetes. Hence the routine screening of cognition by SMMSE should be done in all type-II diabetic patients.


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