Comparison of Adrenaline and Salbutamol nebulization in treatment of Children with Bronchiolitis.

Background: Bronchiolitis is an acute inflammation of bronchioles that can be severe enough to require admission in intensive care unit. There are multiple modalities used for treatment of bronchiolitis. The objective of this study was to compare the response of adrenaline and salbutamol nebulization in terms of clinical improvement and duration of hospital stay. Study Design: Randomized controlled trial. Setting: Pediatrics Department of Avicenna Medical College and Hospital, Lahore. Period: March 2018 to October 2018. Methods: Total 66 patients with 33 in each group between ages of 2-months to 3-years admitted with the diagnosis of bronchiolitis, were included in the study. Children in the group 1 were patients treated with salbutamol nebulization 0.15 mg/kg with 3 ml normal saline every six hourly. Children in the group 2 received adrenaline nebulization 0.1 ml/kg of 1:1000 dilutions with 3 ml normal saline every six hourly. Both the groups were given similar supportive management that included oxygen therapy, intravenous fluids, and antipyretics. Data was collected in the form of age, gender, heart rate, respiratory rate, SpO2 and RDAI score at admission, 6hr, 24 hr and 48hr after admission, duration of hospital stay and duration of oxygen therapy. Results: Out of 66 patients, 38(57.6%) were male and 28(42%) were female. The mean with standard deviation of age in months was 20.45 + 12.9 in salbutamol group and 16.7 + 12.3 in adrenaline group (p value = 0.23). Mean with standard deviation of weight of patients was 9.7+ 3.5 in salbutamol group and 8.9+3.3 in adrenaline group (p value =0.34). Regarding the duration of hospital stay the mean and standard deviation of hospital stay was 4.2+ 0.9 in salbutamol group and 3.9 + 1 in adrenaline group with p value 0.016. Mean and standard deviation of duration of oxygen therapy was 1.05+ 0.7 in salbutamol group and 0.9+0.4 in adrenaline group with p value 0.42. There was no significant difference in the values of RDAI, heart rate, respiratory rate, SPO2 at admission and subsequently after 6hrs, 24hrs, and 48hrs. Conclusion: We concluded that there was a significant reduction in duration of hospital stay in patients who received adrenaline nebulization then those nebulized with salbutamol. RDAI scores in the initial 48 hours in both the groups were improved in successive readings, but there was no significant difference in RDAI scores between the two groups recorded at different time intervals.

Download Full-text

Audit on the Management of Bronchiolitis: A Single Centre Real World Experience in Bangladesh Can We do Better ?

Chattagram Maa-O-Shishu Hospital Medical College Journal ◽

10.3329/cmoshmcj.v14i1.22871 ◽

2015 ◽

Vol 14 (1) ◽

pp. 6-10 ◽

Cited By ~ 1

Author(s):

Farzana Hamid ◽

Syed Moosa MA Quaium ◽

Azizur Rahman ◽

AT Reza Ahmad ◽

Shahariar Khan ◽

...

Keyword(s):

Heart Rate ◽

Oxygen Saturation ◽

Hospital Stay ◽

Respiratory Rate ◽

P Value ◽

Supportive Treatment ◽

Significant Difference ◽

Group A ◽

Syncytial Virus ◽

Group B

Background: Bronchiolitis is the most common reason for hospitalization of children in many countries.Though Respiratory Syncytial Virus (RSV) is the most common organism causing bronchiolitis, but antibiotics are used widely.So the aim of the present study is to establish whether antibiotic has any role in bronchiolitis management along with supportive treatment. Methods:This retrospective study included 100 infants and children between 2-24 months of age admitted with clear cut sign symptoms of bronchiolitis. Patients were divided into Group A (supportive + antibiotic Rx) comprised 72 patients and group B (supportive Rx only) comprised 28 patients.After 3-5 days of hospital stay, clinical responses were evaluated in terms of improvement in symptoms and clinical parameters- respiratory rate, heart rate and oxygen saturation. Results: Mean age of patients was 6.6 (±5.6) months in Group A and 6.3 (±4.8) months in Group B. Most of the patients in both study groups were male (M: F=1.6:1). All the cases in both groups presented with cough, running nose, and respiratory distress. Fever and feeding difficulty were present in 83.3% & 90.3% in Group A and 82.1% & 89.3% in Group B respectively. Majority of cases were from lower socioeconomic status and lived in urban area. In Group A, after therapy mean respiratory rate 53.7 (±4.3) and oxygen saturation 97.9 (±1.9) had significantly improved in comparison to respiratory rate 65.6 (±4.8) and oxygen saturation 89.7 (±4.4) before therapy (p=<.001 in all parameter). Heart rate also significantly increased after therapy (149.4 ±10.2 versus 104.5 ±8.7) (p=<.001). In Group B, after therapy mean respiratory rate 53.5 (±4.1) and oxygen saturation 97.8 (±1.7) had also significantly improved in comparison to respiratory rate 65.3 (±4.1) and oxygen saturation 88.8 (±2.8) before therapy (p=<.001 in all parameter). Heart rate also significantly increased after therapy (150.8 ±9.8 versus 105.0 ±6.2) (p=<.001). In comparison between two modalities of treatment, no significant difference was found (p value=>.05 in all parameters). No statistical significant difference was observed in the length of hospital stay in two groups. Conclusion: The study highlighted the importance of supportive treatment in bronchiolitis management. Antibiotics should not be used without clinical and laboratory evidence of bacterial infection. DOI: http://dx.doi.org/10.3329/cmoshmcj.v14i1.22871 Chatt Maa Shi Hosp Med Coll J; Vol.14 (1); Jan 2015; Page 6-10

Download Full-text

TO COMPARE THE EFFECTIVENESS OF NEBULISATION WITH ADRENALINE, 3% HYPERTONIC SALINE AND NORMAL SALINE IN BRONCHIOLITIS IN CHILDREN OF 2 TO 24 MONTHS OF AGE BASED ON CLINICAL SEVERITY SCORE AND NEBULISATION FREQUENCY.

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v5i2.1764 ◽

2021 ◽

Vol 5 (2) ◽

Author(s):

Priyanka Jain ◽

Rakesh Jain

Keyword(s):

Hypertonic Saline ◽

Normal Saline ◽

Mean Difference ◽

Clinical Severity ◽

Research Centre ◽

P Value ◽

College Hospital ◽

Mean Values ◽

Significant Difference ◽

The Mean

Background & Method: We conducted a double blinded study at Index Medical College Hospital & Research Centre, Indore. The sample size was determined to be minimum of 120 cases as based upon previous years admission due to acute bronchiolitis. Initially, 146 cases were included in the study out of which 23 cases dropped out of the study after giving consent by guardian for participation in the study as they left against medical advice from the hospital. Result: The mean difference of CSS between 0 minutes to 60 minutes of nebulisation between groups in all cases was 0.4 ± 0.6, between 60 minutes and 4 hours was 0.8 ± 0.6, between 4 to 8 hours was 0.7 ± 0.6, between 8-12 hours was 0.6 ± 0.4, between 12-24 hours was 1.6 ± 0.9 and between 24-48 hours was 1.9 ± 0.9.The mean values and resultant p-value of ANOVA of various nebulising agents used for improvement in CSS shows significant association between various nebulising agents used along with improvement in CSS at the end of assessment at 48 hours of treatment. Conclusion: This study was conducted to establish the efficacy of each nebulisation agent (i.e. adrenaline, 3% hypertonic saline and normal saline) currently used and compare the outcomes as there is not enough evidence amongst Indian population on level of efficacy of each drug in causing improvement in symptoms and signs in various severities of bronchiolitis in early childhood. Comparison of significant improvement in mean difference in CSS at various intervals in all cases compared between groups by post hoc test revealed non-significant difference (p-value 0.700) between 3% hypertonic saline and normal saline. Keywords: nebulisation, adrenaline, bronchiolitis & clinical.

Download Full-text

Memperbaiki Saturasi Oksigen, Frekuensi Denyut Jantung, dan Pernafasan Neonatus yang Menggunakan Ventilasi Mekanik Dengan Terapi Musik

Jurnal Keperawatan Indonesia ◽

10.7454/jki.v16i3.324 ◽

2013 ◽

Vol 16 (3) ◽

pp. 154-160 ◽

Cited By ~ 1

Author(s):

Rahmadevita S.A.M ◽

Yeni Rustina ◽

Elfi Syahreni

Keyword(s):

Heart Rate ◽

Mechanical Ventilation ◽

Music Therapy ◽

Oxygen Saturation ◽

Respiratory Rate ◽

T Test ◽

P Value ◽

Respiratory Disorder ◽

Significant Difference ◽

Paired T Test

AbstrakNeonatus yang menggunakan ventilasi mekanik akibat gangguan pernapasan mengalami masalah oksigenisasi dan frekuensi denyut jantung. Berbagai upaya perlu dilakukan agar neonates tenang sehingga kebutuhan oksigen dapat diminimalkan, salah satu upaya tersebut adalah terapi musik. Penelitian ini bertujuan untuk menguji pengaruh terapi musik terhadap saturasi oksigen, frekuensi denyut jantung dan frekuensi pernafasan neonatus yang menggunakan ventilasi mekanik. Penelitian kuasi eksperimen dengan rancangan pretest-posttest without control meibatkan 13 neonatus yang dipilih secara konsekutif. Intervensi yang diberikan adalah terapi musik dengan Brahm’s Lullaby selama 30 menit dengan headphone. Pengumpulan data menggunakan observasi dan dianalisis dengan Paired t test. Hasil penelitian menunjukkan adanya perbedaan bermakna antara rerata saturasi oksigen, frekuensi denyut jantung dan frekuensi pernafasan sebelum dan setelah pemberian terapi musik. Pada saturasi oksigen terjadi peningkatan, sedangkan pada frekuensi denyut jantung dan pernapasan mengalami penurunan. Terapi musik dapat digunakan sebagai pendamping terapi medis untuk memperbaiki oksigenisasi pada neonatus yang menggunakan ventilasi mekanik.Kata kunci: denyut jantung neonatus, pernapasan, saturasi oksigen, terapi musik, ventilasi mekanikAbstractImproving Oxygen Saturation, Heart Rate, and Respiratory Rate of Neonates Using Mechanical Ventilation with Music Therapy. Neonates using mechanical ventilation cause of respiratory disorder experience oxygenation and heart rate problems. Interventions should be made in order to calm neonates so that the need of oxygen can be minimized, one of these interventions is music therapy. This study aimed to identify the effect of music therapy on oxygen saturation, heart rate and respiratory rate of neonates using mechanical ventilation. This quasi experiment study with a pretest-posttest design without control involved 13 neonates selected by consecutive sampling. Data collected through observation and analyzed by paired t test. There was a significant difference on the average of oxygen saturation, heart rate and respiratory rate of infants using mechanical ventilation before and after music therapy (p value <0,05). Music therapy can be used as a complementary medical therapies to improve oxygenation in neonates using mechanical ventilation.Key words: heart rate, mechanical ventilation, music therapy, neonate, oxygen saturation, respiratory rate

Download Full-text

Impact of integration through peer instructed lectures

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20172045 ◽

2017 ◽

Vol 6 (6) ◽

pp. 1293 ◽

Cited By ~ 1

Author(s):

Prapthi Persis Bathini ◽

Sumana Sen

Keyword(s):

Standard Deviation ◽

P Value ◽

Knowledge Gain ◽

Peer Assisted Learning ◽

Public Health Importance ◽

Critical Reasoning ◽

Significant Difference ◽

Post Test ◽

The Mean ◽

Case Based

Background: Integrated case based lectures are widely used as an effective method of teaching and learning. This method not only integrates all the disciplines in a particular year but also presents them in an effective case based format. Over the years, the students were less enthusiastic about this method. In order to make it more student centred and to actively involve them we have introduced peer case based integrated lectures. Peer assisted learning is a strong educational strategy known to benefit peer tutors and learners. This study evaluates the Knowledge gain of both the methods to see if there is any significant difference.Methods: Students in their 2nd year MBBS who agreed to participate were included in the study. After a series of discussions with the curriculum committee, the basic and clinical faculty, topics of public health importance were selected and written case scenarios with a set of relevant questions were formulated. In case based integrated lectures for tuberculosis, lectures were taken by faculty of the pertaining disciplines. In the peer case based integrated lectures on HIV, the same were taken by the students. A pre-test and post test was conducted after each session to know if there is a significant difference in knowledge gain in the two formats.Results: For the case based and peer led case based lectures, the mean student attendance was 90% and 86%. In the pre-test of integrated group on tuberculosis the mean score was 9.96 with standard deviation of 2.38. The post-test of the same group, the mean knowledge score was 13.63 with standard deviation of 2.20. There was significant improvement in knowledge with the case based integrated lectures of 3.67. The p value (0.0001) for this intervention is extremely significant. The post-test marks obtained for integrated and peer integrated group were 13.63±2.20 and 15.86±2.39 respectively. The mean increase in knowledge after peer case based integrated group was 6.1 when compared to increase in knowledge after case based integrated group which was 3.67.Conclusions: Integrated case base lectures is an effective teaching learning tool which can be further made student centric by involving students as peer teachers. Peer teaching is a valuable methodology to engage learners as teachers to improve their knowledge and communication skills as well creating an environment in which the peer audience will likely actively discuss and exchange ideas. Peer assisted learning is need of time to increase critical reasoning skills of medical students.

Download Full-text

COMPLICATED INGUINAL HERNIAS;

The Professional Medical Journal ◽

10.29309/tpmj/2019.26.03.3232 ◽

2019 ◽

Vol 26 (03) ◽

Author(s):

Naveed Akhtar ◽

Syed Shams- Ul-Hassan ◽

Muhammad Sabir ◽

M. Nauman Ashraf

Keyword(s):

Inguinal Hernia ◽

Hospital Stay ◽

Wound Infection ◽

P Value ◽

Emergency Setting ◽

Complication Rates ◽

Success Rates ◽

Inguinal Hernias ◽

Significant Difference ◽

The Mean

Background: Herniorrhaphy and hernioplasty are the two most common modalities used with different degree of success and complication rates in the treatment of inguinal hernia. Several studies show that use of mesh is superior to the non-mesh operations in inguinal hernia surgery.It is generally believed that the use of biomaterials should be limited to non-infected surgical fields.Now the concept regarding use of mesh in complicated hernias is changing as shown by many studies. Current study is being planned to observe the outcomes of the mesh hernioplasty in treatment of complicated inguinal hernias in emergency so that in future appropriate and safe technique may be suggested for repair of complicated hernias in emergency setting. Objectives: To compare the outcome of hernioplasty and herniorrhaphy in emergency for the treatment of complicated (Irreducible/obstructed) inguinal hernias regarding wound infection and hospital stay. Material & Methods:… Study Design: Randomized control trial. Setting: Surgical ward, Sheikh Zayed Hospital, Rahim yar khan. Period:09 months from 01-01-2016 to 30-09-2016. Sample Size: A total of 64 patients with 32 patients were included in each group, with confidence level of 95% and power of 80% and anticipated mean level of hospital stay in group 1 of 5±3.4 days versus 3±2.1 days in group 2. Sampling Technique: Non-probability, consecutive sampling. Results: In this study there were total 64 cases with 32 in each group. The mean age was 41.69±11.06 years and the mean duration of hernia obstruction was 12.83±4.97 hours. There was no significant difference in terms of age, duration of hernia and hernial obstruction between both groups. Seroma was seen in 5 (7.81%) out of 64 cases while wound infection was seen in 8 (12.50%) of cases. Seroma was seen in 2 (6.25%) out of 30 cases in herniorrhaphy as compared to 3 (9.38%) out of 32 cases with hernioplasty with p value of 0.64. Wound infection was seen in equally 4 (12.50%) out of 32 cases in both groups with p value of 1.0. Duration of hospital stay was 4.66±1.36 in patients with herniorrhaphy as compared to 4.53±1.37 days with hernioplasty with p value= 0.82. There was no significant difference in terms of age groups, duration of hernia and its obstruction between both groups regarding seroma. There was also no significant association among any of the confounding factors regarding the wound infection and length of the hospital stay between the both groups. Conclusion: We can perform hernioplasty as compared to herniorrhaphy for complicated inguinal hernia with similar complications and better success rates in the same emergency setting.

Download Full-text

Risk of invasive candidiasis with prolonged duration of ICU stay: a systematic review and meta-analysis

BMJ Open ◽

10.1136/bmjopen-2019-036452 ◽

2020 ◽

Vol 10 (7) ◽

pp. e036452

Author(s):

Zhidan Zhang ◽

Ran Zhu ◽

Zhenggang Luan ◽

Xiaochun Ma

Keyword(s):

Hospital Stay ◽

Meta Analysis ◽

Icu Admission ◽

Duration Of Hospital Stay ◽

Icu Stay ◽

Significant Difference ◽

The Mean ◽

Meta Regression ◽

Length Of Icu Stay ◽

Overall Mortality

ObjectiveThis study aimed to evaluate the duration of intensive care unit (ICU) stay prior to onset of invasive candidiasis (IC)/candidaemia.DesignSystematic review and meta-analysis.Data sourcesPubMed, Cochrane, Embase and Web of Science databases were searched through June 2019 to identify relevant studies.Eligibility criteriaAdult patients who had been admitted to the ICU and developed an IC infection.Data extraction and synthesisThe following data were extracted from each article: length of hospital stay, length of ICU stay, duration of ICU admission prior to candidaemia onset, percentage of patients who received antibiotics and duration of their antibiotic therapy prior to candidaemia onset, and overall mortality. In addition to the traditional meta-analyses, meta-regression was performed to explore possible mediators which might have contributed to the heterogeneity.ResultsThe mean age of patients ranged from 28 to 76 years across selected studies. The pooled mean duration of ICU admission before onset of candidaemia was 12.9 days (95% CI 11.7 to 14.2). The pooled mean duration of hospital stay was 36.3±5.3 days (95% CI 25.8 to 46.7), and the pooled mean mortality rate was 49.3%±2.2% (95% CI 45.0% to 53.5%). There was no significant difference in duration of hospital stay (p=0.528) or overall mortality (p=0.111), but a significant difference was observed in the mean length of ICU stay (2.8 days, p<0.001), between patients with and without Candida albicans. Meta-regression analysis found that South American patients had longer duration of ICU admission prior to candidaemia onset than patients elsewhere, while those in Asia had the shortest duration.ConclusionsPatients with IC are associated with longer ICU stay, with the shortest duration of ICU admission prior to the candidaemia onset in Asia. This shows a more proactive strategy in the diagnosis of IC should be considered in caring for ICU patients.

Download Full-text

Harmonic scalpel versus titanium clips and l-hook in the ligation of cystic duct and artery and gall bladder dissection in laparoscopic cholecystectomy

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20175075 ◽

2017 ◽

Vol 5 (12) ◽

pp. 5145

Author(s):

Anand Vijayvargiya ◽

S. K. Jain ◽

Varsha Soni

Keyword(s):

Laparoscopic Cholecystectomy ◽

Gall Bladder ◽

Hospital Stay ◽

Cystic Duct ◽

Harmonic Scalpel ◽

P Value ◽

Duration Of Hospital Stay ◽

Significant Difference ◽

Conversion To Open Cholecystectomy ◽

Duration Of Surgery

Background: Laparoscopic cholecystectomy is a gold standard for gall bladder stone surgery. The Aim and objective of study was to compare the total duration of surgery, intraoperative complication like bile leak from cystic duct stump, spillage of bile from gallbladder and post op pain and abdomen distension and jaundice.Methods: Study was carried out in dept. of gen Surgery, Govt medical college Kota in yr. 2015-16 in a total of 50 patients with cholelithiasis with cholecystitis. Patient were equally divided randomly into two groups (a) Harmonic scalpel group and (b) Titanium Clip and L hook group. All patients with medical comorbidities, Concomitant CBD calculi, cirrhosis and portal HT were excluded from study. Intraoperatively adhesions, bile spillage from GB and cystic duct stump noted Postoperatively complain like pain abdomen, Jaundice, and fever were noted. Duration of hospital stay was observed. All results were statistically analyzed using Chi square and ANOVA test.Results: Both groups were comparable on the basis of age and sex distribution, as no statistically difference was noted (P value 0.867 and 0.999 respectively). Intraoperative findings were adhesions 5 in clip group and 7 in harmonic group. Spillage from gall bladder was 2 in Clip group and 3 in harmonic group. Mean duration of surgery was 65.20 min in clip group and 63.68 in harmonic group with no statistically significant difference in both the group (P Value 0.727). Average duration of hospital stay was similar in both the groups with a mean of 2.6 days. Postoperative complication was fever, abdomen pain and distension were 3,1,1 were respectively in the clip group and 3,2,2 respectively in harmonic group with the P value of 0.999 which was statistically insignificant. No CBD injury was noted in any case. Conversion to open cholecystectomy was not done in any case. On 1week and 1 month follow up 2 cases in clip group and 1 in HS group had collection in gall bladder fossa and none at I month.Conclusions: Harmonic scalpel offers an effective, alternative and safe method to cystic duct division and Gallbladder dissection from liver bed.

Download Full-text

PERBANDINGAN EFEKTIVITAS BERKUMUR MENGGUNAKAN LARUTAN PROPOLIS LEBAH 12,38% (APIS MELLIFERA) DAN KLORHEKSIDIN GLUKONAT 0,2 % TERHADAP INDEKS PLAK

Andalas Dental Journal ◽

10.25077/adj.v2i1.111 ◽

2014 ◽

Vol 2 (1) ◽

pp. 46-55

Author(s):

Dara Puspita Harvi ◽

Nur Indrawati Lipoeto ◽

Hidayati Hidayati

Keyword(s):

Apis Mellifera ◽

Standard Deviation ◽

Side Effects ◽

Dental Plaque ◽

Chlorhexidine Gluconate ◽

Plaque Index ◽

P Value ◽

Significant Difference ◽

The Mean ◽

Dental Plaque Index

Dental plaque is the primary etiologic in the development of caries and periodontal disease. Chlorhexidine gluconate 0.2% is the mouthwash that is widely used and effective in reducing dental plaque index, but this mouthwash is chemical with few side effects if used for long periods. Propolis is a bee product that has a high content of flavonoids antibacterial and has many benefits in health and has minimal side effects because it belongs to natural product. This study aims to determine differences in the gargling effectiveness using Chlorhexidine gluconate 0.2% and bee propolis solution 12.38% (Apis mellifera) in reducing dental plaque index. The method used in this research was a clinical experimental with the design of one group pretest and posttest. The subjects consisted of 20 students of MA DR. Abd. Ahmad PGAI Padang. Dental plaque index was measured using PHP plaque index before and after gargling using the solution of bee propolis (Apis mellifera) 12.38% and chlorhexidine gluconate 0.2%. The data of research findings were analyzed using paired T-test (p<0.05). The results show that the mean of plaque index reduction of gargling using the solution of bee propolis 12.38% (Apis mellifera) is 0,88 with the standard deviation of ± 0.66 and the mean of plaque index of gargling using Chlorhexidine gluconate 0. 2% is 1.56 with the standard deviation of ± 0.79. There is a significant difference with p value = 0.005 (p <0.05). Chlorhexidine gluconate 0.2% shows higher reduction, but this mouthwash is the chemical with few side effects, while the solution of bee propolis 12.38% (Apis mellifera) is a natural substance that is safer to use.

Download Full-text

Comparative study of papaya dressing versus normal saline dressing in healing of ulcers

International Surgery Journal ◽

10.18203/2349-2902.isj20171020 ◽

2017 ◽

Vol 4 (4) ◽

pp. 1209

Author(s):

Vasuki V. ◽

Thanmaran N. B. ◽

Vimalakaran B. ◽

Madan K.

Keyword(s):

Standard Deviation ◽

Normal Saline ◽

Clinical Severity ◽

Necrotic Tissue ◽

College Hospital ◽

Ulcer Size ◽

Wound Debridement ◽

Significant Difference ◽

The Mean ◽

Enzymatic Debridement

Background: Chronic non-healing wounds pose a remarkable challenge to health professionals and drain our resources. In recent years, prevalence of diabetic foot ulcers is growing at epidemic proportion in India and worldwide. There are various modalities available for wound debridement. In present study, authors have compared two debridement methods, one which we use regularly in their hospital, wet to dry normal saline dressing and enzymatic debridement with papaya.Methods: This was a randomized, comparative interventional study of 100 patients carried out in Kilpauk Medical College Hospital from August 2013 to August 2014 to compare to efficacy of papaya dressing over normal saline dressing in chronic non-healing wounds.Results: The mean reduction in slough/necrotic tissue in at time of inclusion in study and four week after the study was assessed. In saline dressing, mean reduction was 13.156, standard deviation 3.4558. The mean reduction in slough/necrotic tissue in papaya dressing 10.5, standard deviation 0.7071. There was significant difference in percentage reduction in slough/necrotic tissue within the two groups. Similarly, for the cases with active ulcer, the size assessment at the time of inclusion in the study and three week after was again analysed using student t-test and the mean ulcer size in papaya dressing 2.5062 and standard deviation 1.504. Mean ulcer size in normal saline dressing 2.1564 and standard deviation 1.2961.Conclusions: Present study concluded that favourable and significant ulcer healing rate with improvement and reduction in clinical severity suggests that enzymatic debridement with papaya dressing plays an important role in management of chronic non-healing ulcers.

Download Full-text

Short-Term Effects of Hydrokinesiotherapy in Hospitalized Preterm Newborns

Rehabilitation Research and Practice ◽

10.1155/2016/9285056 ◽

2016 ◽

Vol 2016 ◽

pp. 1-8 ◽

Cited By ~ 2

Author(s):

Welcy Cassiano de Oliveira Tobinaga ◽

Cirlene de Lima Marinho ◽

Vera Lucia Barros Abelenda ◽

Paula Morisco de Sá ◽

Agnaldo José Lopes

Keyword(s):

Heart Rate ◽

Oxygen Saturation ◽

Respiratory Rate ◽

Salivary Cortisol ◽

Short Term ◽

Peripheral Oxygen Saturation ◽

Significant Difference ◽

The Mean ◽

Preterm Newborns ◽

Short Term Effects

Background. In the neonatal intensive care unit (NICU) environment, preterm newborns are subject to environmental stress and numerous painful interventions. It is known that hydrokinesiotherapy promotes comfort and reduces stress because of the physiological properties of water.Objective. To evaluate the short-term effects of hydrokinesiotherapy on reducing stress in preterm newborns admitted to the NICU.Materials and Methods. Fifteen preterm newborns underwent salivary cortisol measurement, pain evaluation using the Neonatal Infant Pain Scale (NIPS), and heart rate, respiratory rate, and peripheral oxygen saturation measurements before and after the application of hydrokinesiotherapy.Results. The mean gestational age of the newborns was34.2±1.66weeks, and the mean weight was1823.3±437.4 g. Immediately after application of hydrokinesiotherapy, a significant reduction was observed in salivary cortisol(p=0.004), heart rate(p=0.003), and respiratory rate(p=0.004)and a significant increase was observed in peripheral oxygen saturation(p=0.002). However, no significant difference was observed in the NIPS score(p>0.05).Conclusion. In the present study, neonatal hydrotherapy promoted short-term relief from feelings of stress. Neonatal hydrokinesiotherapy may be a therapeutic alternative. However, this therapy needs to be studied in randomized, crossover, and blinded trials. This trial is registered withNCT02707731.

Download Full-text