scholarly journals The bacterial spectrum of spontaneous bacterial peritonitis in patients with cirrhosis of liver.

2020 ◽  
Vol 27 (10) ◽  
pp. 2099-2103
Author(s):  
Ahmad Nawaz Babar ◽  
Shahid Rasool ◽  
Salman Azhar ◽  
Javeria Komal ◽  
Sofia Hanif
Keyword(s):  
Clinical Symptoms ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Bacterial Peritonitis ◽  
Bacterial Spectrum ◽  
Study Results ◽  
Cirrhotic Patients ◽  
Cirrhosis Of Liver ◽  
Study Setting ◽  
Symptoms And Signs

Objectives: To identify the bacterial spectrum of SBP in patients with cirrhosis of liver. Study Design: Descriptive Cross-sectional study. Setting: Department of Gastroenterology and Hepatology, Madina Teaching Hospital, Faisalabad. Period: 1st November, 2018 – 30th June, 2019. Material & Methods: Two hundred and fifty cirrhotic patients having ascites and clinical symptoms and signs of SBP, consecutively admitted in the ward or presented to OPD were included in the study. Results: A total of 250 patients included in this study. SBP was diagnosed according to the predetermined criteria in 140 patients.  The culture-negative ascites was found in 77 (55%) and culture-positive ascites was found in 63 (45%) patients. The most common organism was E.Coli 28 (47.45%) followed by Enterococcus 10 (16.94%), Klebsiella Pneumoniae 6 (10.17%), Streptococcal Pneumoniae 5 (8.47%), S.aureus 5 (8.47%), Acinetobacter 3 (5.08%) and miscellaneous 2 (3.38%). Conclusion: The percentage of SBP is quite high among patients having cirrhosis and ascites and the Gram-negative bacterial spectrum is still much common in our region.

scholarly journals DIABETIC NEPHROPATHY

2016 ◽  
Vol 23 (02) ◽  
pp. 121-128
Author(s):  
Jahangir Liaquat ◽  
Muhammad Adnan Bawany ◽  
Noman Shaikh ◽  
Adnan Ali Khahro ◽  
Falak Naz
Keyword(s):  
Type 1 Diabetes ◽  
Diabetic Nephropathy ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Cross Sectional ◽  
Study Results ◽  
Study Setting ◽  
Symptoms And Signs

Objectives: To find out the frequency of hypoglycemia in patients with diabeticnephropathy. Study Design: Cross sectional study. Setting: Emergency department anddepartment of medicine Liaquat university Hospital Hyd/ Jamshoro. Study Period: One yearfrom 01-03-2009 to 28-02-2010. Methodology: Two hundred cases of diabetic nephropathy onthe basis of symptoms and signs of hypoglycemia were selected in this study. Results: Out of200 patients, 102(51%) were males and 98(49%) were females, 10.5% had type-1 diabetes and89.5% had type-2 diabetes. Most of the patients belonged to 60 to 75 years of age. The averageduration of diabetes was 12.20 ± 6.14 years. Out of 23 hypoglycemic patients, 5 (21.7%)had type-1 diabetes in which 4 were male and one was female while 18 (78.3%) had type-2diabetes in which 10 were male and 8 were female patients. Conclusion: It was observed thathypoglycemia

scholarly journals The pattern of microbial flora in Spontaneous bacterial peritonitis in Cirrhotic patients

2020 ◽  
pp. 62-67
Author(s):  
Sehrish Jahan Asif ◽  
Murataza Gondal ◽  
Shahida Parveen ◽  
Sumera Mushtaq ◽  
Shumaila Awan ◽  
...  
Keyword(s):  
Ascitic Fluid ◽  
Spontaneous Bacterial Peritonitis ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
E Coli ◽  
Bacterial Peritonitis ◽  
Serious Infection ◽  
Culture Sensitivity ◽  
Cirrhotic Patients ◽  
Biochemical Examination

Background: Spontaneous bacterial peritonitis (SBP) is the bacterial infection of ascitic fluid in the absence of other apparent causes. It is the most prevalent and serious infection in cirrhosis and leads to significant morbidity and mortality. The frequency of SBP in hospitalized patients with cirrhosis varies from 7 to 23% in the west and it is around 33% in Pakistan. Our study aim was to determine the frequency of microbial organisms isolated from spontaneous bacterial peritonitis in cirrhotic patients. Material and Methods: We did a cross-sectional study at the Department of Medicine, Fauji Foundation Hospital Rawalpindi for 6 months. Cirrhosis was diagnosed on the bases of clinical, biochemical and ultrasonography findings. Peripheral blood samples were obtained for the evaluation of complete blood cell count, polymorphonuclear leukocyte count, albumin and coagulation parameters. At the same time, the patients underwent paracentesis and a 20ml ascitic fluid sample was taken for culture sensitivity along with routine biochemical examination from the pathology department lab at our hospital. Results: A total of 150 patients were enrolled according to the inclusion criteria of the study. The mean age (yrs) of patients was 32.3+9.31. The frequency and percentages of male and female patients were 70 (46.7) and 80 (53.3) respectively. Frequency and percentages of E Coli and streptococcal pneumonia were 94 (62.7) and 34 (22.7) respectively, whereas frequency and percentages of staph aureus and Klebsiella were 22 (14.7). Conclusion: SBP is quite common in patients with cirrhosis. It should be suspected in all such cases presenting with typical or atypical features. E Coli was the most common causative organisms in our study but gram-positive organisms were quite frequent as well. Keywords: SBP, Cirrhosis, Peritonitis.

scholarly journals SPONTANEOUS BACTERIAL PERITONITIS

2018 ◽  
Vol 25 (02) ◽  
pp. 302-306
Author(s):  
Noor Gul ◽  
Tahir Habib Rizvi ◽  
Memoona Alam
Keyword(s):  
Liver Cirrhosis ◽  
Frequency Distribution ◽  
Spontaneous Bacterial Peritonitis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Bacterial Peritonitis ◽  
Medical Wards ◽  
Study Setting

Objectives: To record frequency of spontaneous bacterial peritonitis in patientsof liver cirrhosis with low ascitic protein contents. Methodology: This study included 81 patientswith liver cirrhosis with low ascitic proteins level. All the patients were evaluated for the presenceof spontaneous bacterial peritonitis which was described as frequency distribution table. StudyDesign: Cross Sectional Study. Setting: Medical wards of DHQ and Allied Hospitals (PunjabMedical College) Faisalabad. Duration of Study: 11th May 2011 to 10th November 2011.Results: Spontaneous bacterial peritonitis was present among 29 (35.8%) patients and wasnot present among 52 (64.2%) patients. Conclusion: All the patients with low ascitic proteinlevel should be evaluated for the presence of spontaneous bacterial peritonitis and antibioticprophylaxis should be considered.

scholarly journals Prevalence of hyponetremia in cirrhotic patients with encephalopathy.

2021 ◽  
Vol 28 (09) ◽  
pp. 1308-1314
Author(s):  
Tauqeer Shaikh ◽  
Hamid Ali Kalwar ◽  
Ghulam Mujtaba ◽  
Adeel Rahat ◽  
Kamaran Ali ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Neurological Impairment ◽  
Cross Sectional Study ◽  
Common Finding ◽  
National Hospital ◽  
Cross Sectional ◽  
Early Management ◽  
Ethical Approval ◽  
Cirrhotic Patients ◽  
Study Setting

Objective: To Determine the frequency of hyponatremia in cirrhotic patients with encephalopathy. Study Design: Cross Sectional Study. Setting: Department of Gastroenterology Liaquat National Hospital Karachi. Period: 6 Dec 2017 to 6 June 2018. Material & Methods: All those fulfilling the inclusion criteria and admitted in the Gastroenterology department of Liaquat National Hospital Karachi were taken in the study after their ethical approval alongside an informed and written consent. Brief history was taken, clinical examination was done, and serum sodium level was delivered to the institutional laboratory to reach the outcome i-e hyponatremia. Results: - A number of 369 patients having encephalopathy were taken into study. 207 patients (56.1%) were males and 162 patients (43.9%) were females with an average age of 50.03+10.333 years. Hyponatremia was seen in 138 patients (37.4%). Conclusion: Dilutional hyponatremia is a common finding in liver cirrhosis patients with encephalopathy leading to neurological impairment, hepatorenal syndrome, osteoporosis and high mortality. Therefore, early management of hyponatremia is key to prevent liver cirrhosis related complications.

scholarly journals Evaluation of Serum Presepsin in the Diagnosis and the Prognosis of Cirrhotic Patients with Ascites

2021 ◽  
pp. 62-69
Author(s):  
Aziza Mohamed Hamed Zian ◽  
Mervat Abd El-Hameed Elkhateeb ◽  
Amira Youssef Ahmed ◽  
AL Zahraa Abd El-Azeam Allam
Keyword(s):  
Internal Medicine ◽  
Bacterial Infections ◽  
Spontaneous Bacterial Peritonitis ◽  
Hepatorenal Syndrome ◽  
Significant Negative Correlation ◽  
Cross Sectional Study ◽  
Clinical Value ◽  
Cross Sectional ◽  
Bacterial Peritonitis ◽  
Cirrhotic Patients

Background: Liver cirrhosis is a serious problem associated with spontaneous bacterial peritonitis and renal dysfunction. Presepsin is a soluble Cluster of Differentiation 14 (CD14) Protein subtype that has been implicated as an important biomarker in many diseases. Objective: To assess the clinical value of presepsin as a diagnostic and prognostic marker for spontaneous bacterial peritonitis in cirrhotic patients.  Patients and Methods: This cross-sectional study was carried out on 60 cirrhotic patients with ascites. The data were collected from Internal Medicine Hospital Inward and ICUs of Internal Medicine. Results: Serum presepesin had a significant negative correlation with serum albumin (rs = -0.350, p = 0.006) and a significant positive correlation with platelet count (rs =0.547, p < 0.001). In the Spontaneous bacterial peritonitis (SBP) group, presepesin correlated significantly positively with total leukocytic count (rs =0.547, p < 0.001). The level of serum presepsin significantly increased with the group suffering from Hepatorenal syndrome (HRS) than the ascites group after adjusting for age, C-reactive Protein (CRP) level, and total leukocytic count. Similarly, the level of serum presepsin significantly increased with the SBP group than the ascites group after adjusting for age, CRP level, and total leukocytic count. Conclusion: presepsin is a promising biomarker in the diagnosis of bacterial infections and hepatorenal syndrome in cirrhosis. However, the diagnostic and prognostic value of presepsin needs further studies.

scholarly journals H.PYLORI INFECTION

2016 ◽  
Vol 23 (03) ◽  
pp. 307-311
Author(s):  
Shabnam Naveed ◽  
Syed Masroor Ahmed ◽  
Zeeshan Ali ◽  
Romana Awan ◽  
Humaira Zakir ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Gastric Ulcer ◽  
Cross Sectional Study ◽  
Rapid Urease Test ◽  
Viral Etiology ◽  
Cross Sectional ◽  
Urease Test ◽  
Cirrhotic Patients ◽  
H Pylori ◽  
Study Setting

Objectives: To study the frequency of H. pylori infection and its association as acause of upper G.I bleeding in cirrhosis. Study Design: Cross Sectional Study. Setting: MedicalUnit III, JPMC Karachi. Period: January 2014 to December 2014. Methods: 100 patients ofestablished cirrhosis with upper G.I bleeding were included in this study. These patients wereevaluated for viral etiology of cirrhosis. An upper G.I Endoscopy was performed in all patientsand antral biopsies were taken. Rapid urease test was performed on biopsy specimen fordetection of H.pylori infection. Results: Out of 100 patients 71 were males and 29 were femaleswith age ranging between 14 to 70 years. Among them 53% patients turned out to be positivefor H.Pylori infection with rapid urease test. H.pylori infection was detected in 68.7% of HBsAgpositive patients and in 50% of Anti HCV positive patients. On upper G.I endoscopy 96 patientshad PHG and among them 50 (52%) were positive for H.pylori. 4 patients did not have PHGand among them 3 (75%) were positive for H.pylori. Gastric ulcer was present in 17 patientsand amongst them H.pylori was detected in 10 (58.8%) cases. Duodenal ulcer was present in 5patients and among them 2 (40%) were positive for H.pylori. Gastritis was present in 17 casesamong them 11 (64%) were positive for H.pylori. Duodenitis was present in 13 cases amongthem 11 (84.6%) patients were positive for H.pylori infection. Conclusion: The frequency ofH.pylori infection was low in cirrhotic patients. No association was seen in H.pylori infectionand causes of upper G.I bleeding in cirrhosis including PHG, gastric ulcer and duodenal ulcer

scholarly journals Morbidities associated with increased BMI in pregnant women.

2019 ◽  
Vol 26 (08) ◽  
pp. 1345-1347
Author(s):  
Sarwat Memon
Keyword(s):  
Age Groups ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Complication Rates ◽  
Sectional Study ◽  
Singleton Pregnancy ◽  
Cross Sectional ◽  
Study Results ◽  
Care Facilities ◽  
Study Setting

Obesity is the major threat to social and medical wellbeing in Pakistan and worldwide. Increased BMI poses certain risks to mother as well as fetus. The objective of this study is to assess the maternal and fetal morbidities in women presenting with increased BMI during pregnancy. Study Design: Descriptive cross sectional study. Setting: Isra University Hospital. Period: 1st June 2017 till Nov 2017. Materials and Methods: 100 Patients with singleton pregnancy were included in this study. Results:                                                                     . Conclusion: It was concluded that there are complex and noteworthy socio- statistic imbalances related to different age groups, parity status and BMI. It was also concluded that increased no of patients are at high risks of maternal and fetal complication rates and require proper access to antenatal care. Facilities and interventions should be provided to improve both maternal and fetal health care and reduce the risks of adverse effects of increased BMI.

scholarly journals COMPLICATIONS OF COLOSTOMY;

2014 ◽  
Vol 21 (03) ◽  
pp. 524-528
Author(s):  
Muhammad Naeem Ashraf ◽  
M. Shahbaz Bakht Kayani ◽  
Shahid Mahmood ◽  
Saad Sultan
Keyword(s):  
Cross Sectional Study ◽  
Morbidity And Mortality ◽  
Sectional Study ◽  
Cross Sectional ◽  
Operative Morbidity ◽  
Number Of Patients ◽  
Study Results ◽  
Study Setting

Objective: To study the frequency and types of complications in colostomypatients. Stuyd Design: Prospective cross sectional study. Setting: Department at Surgery, FaujiFoundation Hospital Rawalpindi. Period: 1st December 2009 to 30th November 2011. Material &methods: A total of 104 consecutive patients who end up with colostomy due to any reason wereincluded in the study. Results: It was noted that 52 patients had stoma due to malignancy andcomplications was noted in 40 patients. Same number of Patients operated for non-malignantdisease i.e. 52. Complications noted in only 24 patients while 28 were without complications.Conclusions: The chances of complications in different type of stomas are much higher in caseof malignancy. It is recommended that such operations are performed by senior surgeons inorder to avoid post-operative morbidity and mortality.

scholarly journals Spontaneous Bacterial Peritonitis and Short-Term Prognosis in a Group of Decompensated Cirrhotic Patients in Yaounde: A Cross-Sectional Study

2020 ◽  
Vol 10 (08) ◽  
pp. 203-213
Author(s):  
Mathurin Pierre Kowo ◽  
Sylvain Raoul Simeni Njonnou ◽  
Nelly Karelle Weyou Noubissi ◽  
Firmin Ankouane Andoulo ◽  
Gabin Ulrich Kenfack ◽  
...  
Keyword(s):  
Spontaneous Bacterial Peritonitis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Short Term ◽  
Cross Sectional ◽  
Bacterial Peritonitis ◽  
Cirrhotic Patients

scholarly journals Evaluating diagnostic value of clinical symptoms and signs for chronic sinusitis by CT-scan in patients admitted to Ardabil city hospital, Iran

2019 ◽  
Vol 6 (3) ◽  
pp. 590
Author(s):  
Tirzad Fouladvand ◽  
Akbar Pirzadeh ◽  
Khatereh Isazadehfar ◽  
Alireza Alipour
Keyword(s):  
Ct Scan ◽  
Chronic Sinusitis ◽  
Clinical Symptoms ◽  
Diagnostic Value ◽  
Cross Sectional Study ◽  
City Hospital ◽  
Cross Sectional ◽  
Clinical Criteria ◽  
Positive Predicted Value ◽  
Symptoms And Signs

Background: Chronic rhinosinusitis (CRS) refers to inflammatory nasal and para nasal sinuses which last at least 12 weeks. Despite its high prevalence, it is not easy to diagnose, and clinical criteria and simple radiographs are not so sensitive. The aim of this study was to investigate the diagnostic value of clinical symptoms and signs for chronic sinusitis by Ct-scan in patients admitted to Ardabil city hospital, Iran.Methods: This descriptive cross-sectional study has been done on 83 patients with CRS symptoms who referred to ENT of Ardabil city hospital. The necessary checklist included information such as age, gender, clinical symptoms and CT scan findings were completed and analyzed by statistical methods in SPSS version 21.Results: Of all 83 patients, 55.4% were female and most of patients were in age group 30-39 years with 30.1%. Of all patients, 29 (35%) had positive findings in CT scan of which 72.4% were female. The highest rate of sinus involvement was in the ethmoid sinus. The highest positive predicted value was for nose congestion with OR=2.26 and the lowest was for facial pain and toothache each with OR=0.1.Conclusions: In general, clinical symptoms have a small predictive value in the diagnosis of sinusitis and should be evaluated with CT scan findings (15.7%).

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