scholarly journals Brain washing systems and other circulating factors in some neurological condition like Parkinson (Pd) and vascular and diabetic dementia: How dynamics- saturation of clearance can act on toxic molecule?

2020 ◽  
Vol 4 (1) ◽  
pp. 001-013
Author(s):  
Luisetto Mauro ◽  
Khan Farhan Ahmad ◽  
Muhamad Akram ◽  
Mashori Ghulam Rasool ◽  
Ahmadabadi Behzad Nili ◽  
...  
Author(s):  
Malika Auvray ◽  
Mirko Farina

Synaesthesia is a neurological condition in which people make unusual associations between various sensations. This chapter investigates conceptually whether alleged non-developmental (i.e. artificial) forms of synaesthesia could be counted as genuine synaesthetic experiences. It focuses in particular on post-hypnotic suggestions, drug habits, flavor perception, and use of sensory substitution devices. It discusses a number of criteria that have been taken as definitional of synaesthesia; namely, inducer-concurrent pairing, idiosyncrasy, consistency over time, and automaticity of the process, and subsequently investigates whether those alleged non-developmental cases could fulfill these criteria. Although the response provided here is negative, as each of the cases fail to fulfill one or several of the criteria, the comparisons between these cases and congenital synaesthesia prove useful to highlight key differences between different kinds of multisensory experiences.


2017 ◽  
Vol 156 ◽  
pp. 55-62 ◽  
Author(s):  
Philipp Hendrix ◽  
Elisa Hans ◽  
Christoph J. Griessenauer ◽  
Andreas Simgen ◽  
Joachim Oertel ◽  
...  

1988 ◽  
Vol 62 (3) ◽  
pp. 979-985 ◽  
Author(s):  
Arthur S. Walters ◽  
Doris Wright ◽  
James Boudwin ◽  
Karl Jones

Three hysterical movement disorders are reported: a case of hysterical bilateral blepharospasm which later presented as hysterical hemifacial spasm, a case of hysterical myoclonus, and a case of hysterical parkinsonism. Two patients presented with a relative indifference to preceding life experiences that would normally have evoked considerable emotion. Two of the cases first presented at an older age and one of these older patients was a man. Two of the patients agreed to hypnotherapy and supportive psychotherapy. In both cases the “involuntary” movements disappeared during hypnosis. In the third case, there was a complete spontaneous resolution of symptoms in a neurological condition where resolution would not be expected to occur.


2021 ◽  
pp. 147775092110698
Author(s):  
Alexia Zagouras ◽  
Elise Ellick ◽  
Mark Aulisio

There is a gap in the clinical bioethics literature concerning the approach to assessment of medical decision-making capacity of adolescents or young adults who demonstrate diminished maturity due to longstanding reliance on caregiver support, despite having reached the age of majority. This paper attempts to address this question via the examination of a particular case involving assessment of the decision-making capacity of a young adult pregnant patient who also had a physically disabling neurological condition. Drawing on concepts from adolescent bioethics and feminist critiques of bioethical theory, we argue that limited life experience, secondary to a disabling neurological condition, can result in a lack of adult-like capacity even in a patient who is legally an adult. In such cases, it may be that autonomy, to the extent that it is to be relevant and meaningful, must be viewed through a relational lens. Furthermore, clinicians may avoid unjustifiably paternalistic practices by working with the patient help her gain a better appreciation of the consequences of her decision, thereby calling forward her capacity rather than resorting to being directive in counseling. We conclude that lessons from this case can be used to approach ethically complex instances of medical decision-making in adult patients with normal cognition but diminished experiential maturity.


1990 ◽  
Vol 23 (1) ◽  
pp. 53-66 ◽  
Author(s):  
Grace Otamiri ◽  
Göran Berg ◽  
Torbjörn Ledin ◽  
Ingemar Leijon ◽  
Birgit Nilsson

2014 ◽  
pp. 677-694 ◽  
Author(s):  
Juan G. Reyes ◽  
Claudia Sánchez-Cárdenas ◽  
Waldo Acevedo-Castillo ◽  
Patricio Leyton ◽  
Ignacio López-González ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (19) ◽  
pp. 5995
Author(s):  
Hallysson Douglas Andrade de Araújo ◽  
Hianna Arely Milca Fagundes Silva ◽  
José Guedes da Silva Júnior ◽  
Mônica Camelo Pessoa de Azevedo Albuquerque ◽  
Luana Cassandra Breitenbach Barroso Coelho ◽  
...  

Usnic acid is the best-studied lichen metabolite, presenting several biological activities, such as antibacterial, immunostimulating, antiviral, antifungal, anti-inflammatory, and antiparasitic agents; despite these relevant properties, it is a hydrophobic and toxic molecule. In this context, scientific research has driven the development of innovative alternatives, considering usnic acid as a source of raw material in obtaining new molecules, allowing structural modifications (syntheses) from it. The purpose is to optimize biological activities and toxicity, with less concentration and/or response time. This work presents a literature review with an analogy of the hydrophobic molecule of usnic acid with its hydrophilic derivative of potassium usnate, emphasizing the elucidation and structural characteristics, biological activities, and toxicological aspects of both molecules, and the advantages of using the promising derivative hydrophilic in different in vitro and in vivo assays when compared to usnic acid.


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