scholarly journals Acute Heart Failure in an Internal Medicine Department: A Prospective Study

2020 ◽  
Vol 18 (1) ◽  
pp. em263
Author(s):  
Rita Reis Correia ◽  
Pedro Leite Vieira ◽  
Marisa Linhares ◽  
Fábia Cruz ◽  
Sandra Martin ◽  
...  
2018 ◽  
Vol 7 (11) ◽  
pp. 386 ◽  
Author(s):  
Gringauz Irina ◽  
Cohen Refaela ◽  
Brom Adi ◽  
Davidi Avia ◽  
Hofstetter Liron ◽  
...  

Background: Low blood ALT, Alanine aminotransferase activity and high FRAIL (Fatigue, Resistance, Ambulation, Illnesses and Loss of Weight) questionnaire scores were previously shown to be associated with frailty and increased risk of mortality. We aimed to correlate these tools with mortality and each other in patients hospitalized in an internal medicine department. Methods: This is a prospective study in a large tertiary hospital. We assessed the predictive value for clinical outcomes of both low ALT blood activity and the pre-frail and frail categories of the “FRAIL” questionnaire. Results: During a 15 months study, 179 consecutive patients were recruited, of whom 20 died. When all study participants were divided to three groups according to admission ALT levels (below 10 IU/L, 11 to 19 IU/L and above 20 IU/L) we found a statistically significant difference in the rate of mortality: 4 patients died within the group of ALT < 10 IU/L, 14 patients died in the group of 10 IU/L < ALT < 19 IU/L and in the group of patients with ALT > 20 IU/L, only 2 patients died (p = 0.042). A higher score on the FRAIL questionnaire was associated, with statistical significance, with higher risk of mortality (p = 0.029). There was a significant correlation (p = 0.038) between blood ALT activity and the pre-frailty and frailty classifications by the FRAIL Questionnaire. Conclusions: Both the FRAIL questionnaire and blood ALT activity are simple and practical tools for frailty assessment and risk stratification of patients hospitalized in the internal medicine department. Both tool’s results also correlate with each other.


Author(s):  
Carlotta Sciaccaluga ◽  
Giulia Elena Mandoli ◽  
Chiara Nannelli ◽  
Francesca Falciani ◽  
Cosimo Rizzo ◽  
...  

2020 ◽  
Vol 9 (8) ◽  
pp. 2659 ◽  
Author(s):  
Sapir Anani ◽  
Gal Goldhaber ◽  
Adi Brom ◽  
Nir Lasman ◽  
Natia Turpashvili ◽  
...  

Background: Frailty and sarcopenia are associated with frequent hospitalizations and poor clinical outcomes in geriatric patients. Ascertaining this association for younger patients hospitalized in internal medicine departments could help better prognosticate patients in the realm of internal medicine. Methods: During a 1-year prospective study in an internal medicine department, we evaluated patients upon admission for sarcopenia and frailty. We used the FRAIL questionnaire, blood alanine-amino transferase (ALT) activity, and mid-arm muscle circumference (MAMC) measurements. Results: We recruited 980 consecutive patients upon hospital admission (median age 72 years (IQR 65–79); 56.8% males). According to the FRAIL questionnaire, 106 (10.8%) patients were robust, 368 (37.5%) pre-frail, and 506 (51.7%) were frail. The median ALT value was 19IU/L (IQR 14–28). The median MAMC value was 27.8 (IQR 25.7–30.2). Patients with low ALT activity level (<17IU/L) were frailer according to their FRAIL score (3 (IQR 2–4) vs. 2 (IQR 1–3); p < 0.001). Higher MAMC values were associated with higher ALT activity, both representing robustness. The rate of 30 days readmission in the whole cohort was 17.4%. Frail patients, according to the FRAIL score (FS), had a higher risk for 30 days readmission (for FS > 2, HR = 1.99; 95CI = 1.29–3.08; p = 0.002). Frail patients, according to low ALT activity, also had a significantly higher risk for 30 days readmission (HR = 2.22; 95CI = 1.26–3.91; p = 0.006). After excluding patients whose length of stay (LOS) was ≥10 days, 252 (27.5%) stayed in-hospital for 4 days or longer. Frail patients according to FS had a higher risk for LOS ≥4 days (for FS > 2, HR = 1.87; 95CI = 1.39–2.52; p < 0.001). Frail patients, according to low ALT activity, were also at higher risk for LOS ≥4 days (HR = 1.87; 95CI = 1.39–2.52; p < 0.001). MAMC values were not correlated with patients’ LOS or risk for re-admission. Conclusion: Frailty and sarcopenia upon admission to internal medicine departments are associated with longer hospitalization and increased risk for re-admission.


2021 ◽  
Vol 331 ◽  
pp. e241
Author(s):  
I. Papakitsou ◽  
V. Mavrikaki ◽  
E. Petrakis ◽  
K. Vasilopoulos ◽  
M. Bagordakis ◽  
...  

Author(s):  
Axler Jean Paul ◽  
Lesly Ed Archer ◽  
Raema Mimrod Jean ◽  
Gérald Vernelus ◽  
Rodolphe Malebranche

Introduction Dilated cardiomyopathy is one of the most frequent causes of heart failure in the world, which is now considered a major public health problem both in developed countries where it is predominant, especially in the elderly, over 65 years of age and in patients on long-term treatment for heart disease, and in underdeveloped countries.The diagnosis of cardiomyopathies is essentially based on para-clinical examinations, more precisely on echocardiography. In Haiti, cardiovascular diseases are the leading causes of hospitalization and mortality. These diseases are the main causes of hospitalization at the Hospital of the State University of Haiti (HUEH), the largest hospital in the country, and represent 30% of all cases received in the internal medicine department. Methodology This is a retrospective quantitative study conducted on a sample of patients in the Cardiology Unit of the Internal Medicine Department of the Hospital of the State University of Haiti (HUEH).The study was conducted on 54 patients registered in the Cardiology Unit, during the period from January 8, 2014 to June 11, 2014 for heart failure. Result and discussion The 50 patients showed a predominance for women, 31 (62%) versus 19 (38%) for men, P=0.04. The results of our study showed that the majority of patients are female (62%), which is similar to the last study conducted on the unit by Dr. Malebranche, who found 62.4%The data showed that the reference examination for the confirmatory diagnosis of cardiomyopathy is echocardiography, with 92% of diagnoses. It should be noted that the other diagnoses were made on an echocardiographic basis but were not complete. These findings are similar to data from a recently published Swedish study in which cardiomyopathy was diagnosed by echocardiography in 99.6% of cases. For chest radiography, 100% of cases have cardiomegaly.65.96% of all heart failure cases are dilated cardiomyopathies compared to undiluted cardiomyopathies 14.89%, p<0.0001


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