scholarly journals Evaluación ecográfica de la función diafragmática en el paciente crítico

2019 ◽  
Vol 11 (2) ◽  
pp. 1
Author(s):  
Luisa María Charco Roca ◽  
Elena Simón Polo
Keyword(s):  
Simple Technique ◽  
Reliable Data ◽  
Invasive Technique ◽  
Functional Evaluation ◽  
Diaphragmatic Dysfunction ◽  
Non Invasive ◽  
Diaphragmatic Function ◽  
Pathological Conditions ◽  
Ultrasound Evaluation ◽  
Diaphragmatic Movement

La ecografía ha surgido como una técnica no invasiva que se puede utilizar en la evaluación estructural y funcional del diafragma. Los ultrasonidos permiten observar el movimiento diafragmático en una variedad de condiciones normales y patológicas. Exponemos cuatro casos clínicos en los que la evaluación de la disfunción diafragmática por ecografía permitió hacer un diagnóstico del origen de la insuficiencia respiratoria de forma rápida y no invasiva. La ecografía del diafragma tiene su aplicación principalmente en pacientes en cuidados intensivos y en un futuro podría valorarse como modalidad de elección para la evaluación de la parálisis del diafragma con potencial aplicación clínica para el destete de la ventilación mecánica y diagnóstico diferencial de las causas de insuficiencia respiratoria. ABSTRACT Ecographic evaluation of diaphragmatic function in critical ill patient Ultrasound is a non-invasive technique that can is used in the structural and functional evaluation of the diaphragm. Ultrasounds facilitates the study of diaphragmatic movement in a variety of normal and pathological conditions. We present four clinical cases in which the evaluation of diaphragmatic dysfunction by ultrasound showed the origin of respiratory failure quickly and easily. Ultrasound evaluation of diaphragm function in critically ill patients is a useful and simple technique. It provides fast and reliable data for the diagnosis of respiratory insufficiency of neuromuscular origin with clinical application for weaning from mechanical ventilation and differential diagnosis of the causes of failure respiratory.  

scholarly journals HYPERPIGMENTED AND HYPOPIGMENTED LESIONS – THROUGH THE EYES OF DERMOSCOPE.

2021 ◽  
pp. 151-155
Author(s):  
Nisha M Varma ◽  
S.N. Agrawal ◽  
G.R. Mundhada
Keyword(s):  
Cutaneous Melanoma ◽  
Simple Technique ◽  
Skin Lesions ◽  
Accurate Diagnosis ◽  
Invasive Technique ◽  
Seborrheic Keratosis ◽  
Non Invasive ◽  
Pigmented Lesions ◽  
Doctor's Office ◽  
Complementary Examination

Dermoscope is a very useful and non-invasive technique for diagnosis of pigmentary skin lesions. It helps in diagnosis of skin lesions like seborrheic keratosis , spitz nevus which may clinically simulate melanoma. It involves a complementary examination of pigmented lesions on the skin, increasing the chance of an accurate diagnosis of cutaneous melanoma. It is a relatively simple technique that can be carried out in a doctor's office, clinic, or hospital, with the use of a portable device (manual dermatoscope).In this article we are presenting the dermoscopic features of common hyper and hypopigmented skin lesions . The goal is to introduce this subject to those not yet familiar with it, in order to instigate and encourage the training and practice of this technique of growing importance for everyday usage.

scholarly journals Liquid Biopsy: A Family of Possible Diagnostic Tools

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1391
Author(s):  
Battistelli Michela
Keyword(s):  
Liquid Biopsy ◽  
Maternal Plasma ◽  
Diagnostic Tools ◽  
Invasive Technique ◽  
Liquid Biopsies ◽  
Non Invasive ◽  
Pathological Conditions ◽  
Different Types ◽  
Functional Involvement ◽  
Invasive Evaluation

Liquid biopsies could be considered an excellent diagnostic tool, in different physiological or pathological conditions. The possibility of using liquid biopsies for non-invasive clinical purposes is quite an old idea: indeed many years ago it was already being used in the field of non-invasive prenatal tests (NIPT) for autosomal fetal aneuploidy evaluation. In 1997 Lo et al. had identified fetal DNA in maternal plasma and serum, showing that about 10–15% of cfDNA in maternal plasma is derived from the placenta, and biologic fluid represents an important and non-invasive technique to evaluate state diseases and possible therapies. Nowadays, several body fluids, such as blood, urine, saliva and other patient samples, could be used as liquid biopsy for clinical non-invasive evaluation. These fluids contain numerous and various biomarkers and could be used for the evaluation of pathological and non-pathological conditions. In this review we will analyze the different types of liquid biopsy, their potential role in clinical diagnosis and the functional involvement of extracellular vesicles in these fluids as carriers.

scholarly journals 1173 Additional role of FFRct and stress CT perfusion in the management of patients with stable chest pain compared to cCTA alone

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
A Baggiano ◽  
M Guglielmo ◽  
G Muscogiuri ◽  
L Fusini ◽  
A Del Torto ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Coronary Artery Disease ◽  
Chest Pain ◽  
Coronary Artery ◽  
Invasive Technique ◽  
Functional Evaluation ◽  
Fractional Flow ◽  
Non Invasive ◽  
Artery Disease ◽  
Stable Chest Pain

Abstract Background Computed tomography-derived fractional flow reserve (FFRCT) and stress computed tomography perfusion (stress-CTP) are new techniques that combine anatomy and functional evaluation to improve assessment of coronary artery disease (CAD) using coronary computed tomography angiography (cCTA). Purpose This study sought to determine the effect of adding FFRCT and stress-CTP to cCTA alone for assessment of lesion severity and patient management of patients referred for chest pain. Methods 289 patients with stable chest pain scheduled for clinically indicated invasive coronary angiography (ICA) plus invasive FFR were evaluated with cCTA, FFRCT, and stress-CTP. Of 289 patients, 147 underwent static stress-CTP, while 142 were evaluated with dynamic stress-CTP. Management plan with optimal medical therapy (OMT) or percutaneous coronary intervention (PCI) for each patient according to results of each non-invasive technique was recorded, and then compared to what effectively applied according to results of reference standard technique (ICA + FFR). The primary endpoints for the study were the correct allocation of patients to OMT or PCI using cCTA, cCTA + FFRCT and cCTA + stress-CTP, and the correct assessment of non-invasive techniques for all three vessels in relation to angiographically and FFR-defined significance. Results Compared to cCTA alone, the addition of FFRCT and stress-CTP to cCTA alone increased the agreement in allocating patients to OMT from 24% to 38% and 44%, respectively, while the addition of FFRCT and stress-CTP to cCTA alone increased the agreement in allocating patients to PCI from 29% to 32% and 36%, respectively. Using ICA + FFR as standard reference, cCTA showed agreement for all three vessels in 56% of patients, while combined approaches of cCTA + FFRCT and cCTA + stress-CTP showed agreement in 66% and 82% of patients, respectively. Conclusions The addition of functional assessment with FFRCT or Stress-CTP to cCTA has a substantial effect on the evaluation of the relevance of coronary artery disease and therefore on the management of patients compared to cCTA alone.

USING DOPPLER TO ASSESS THE FETAL HEALTH FOR THE PREDICTION OF GESTATIONAL OUTCOME

2014 ◽  
pp. 9-18
Author(s):  
Thi Linh Giang Truong ◽  
Vu Quoc Huy Nguyen
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Umbilical Artery ◽  
Functional Method ◽  
Invasive Technique ◽  
Routine Practice ◽  
Fetal Health ◽  
Uterine Arteries ◽  
Non Invasive ◽  
Key Words Doppler

Background: Assessment of fetal health plays the most important role in prenatal care because of influence of the prediction of gestational outcome. One of the main aims of routine antenatal care is to identify the ‘ at risk ‘ fetus in order to apply clinical interventions which could results in reduced perinatal morbidity and mortality. Doppler ultrasound is a non invasive technique whereby the movement of blood is studied by detecting the change in frequence of reflected sound, Doppler blood flow velocity waves form of fetal side (umbilical artery, middle cerebral artery ...) and maternal side ( uterine arteries) are discussed and monograms for routine practice are presented. Recently this method is important tool for qualifying high risk pregnancies and help early forecasts the health of the babies and mothers disorder. Doppler sonography in obstetrics is a widely accepted functional method of examining the prediction of gestational outcome. Key words: Doppler, umbilical artery, middle cerebral artery, uterine arteries

scholarly journals Thermal Liquid Biopsy (TLB) Focused on Benign and Premalignant Pancreatic Cyst Diagnosis

2020 ◽  
Vol 11 (1) ◽  
pp. 25
Author(s):  
Sonia Hermoso-Durán ◽  
Guillermo García-Rayado ◽  
Laura Ceballos-Laita ◽  
Carlos Sostres ◽  
Sonia Vega ◽  
...  
Keyword(s):  
Liquid Biopsy ◽  
Pancreatic Cyst ◽  
Point Of View ◽  
Invasive Technique ◽  
Background Current ◽  
Interesting Point ◽  
Pancreatic Lesion ◽  
Non Invasive ◽  
Patient Diagnosis ◽  
New Biomarkers

Background: Current efforts in the identification of new biomarkers are directed towards an accurate differentiation between benign and premalignant cysts. Thermal Liquid Biopsy (TLB) has been previously applied to inflammatory and tumor diseases and could offer an interesting point of view in this type of pathology. Methods: In this work, twenty patients (12 males and 8 females, average ages 62) diagnosed with a pancreatic cyst benign (10) and premalignant (10) cyst lesions were recruited, and biological samples were obtained during the endoscopic ultrasonography procedure. Results: Proteomic content of cyst liquid samples was studied and several common proteins in the different groups were identified. TLB cyst liquid profiles reflected protein content. Also, TLB serum score was able to discriminate between healthy and cysts patients (71% sensitivity and 98% specificity) and between benign and premalignant cysts (75% sensitivity and 67% specificity). Conclusions: TLB analysis of plasmatic serum sample, a quick, simple and non-invasive technique that can be easily implemented, reports valuable information on the observed pancreatic lesion. These preliminary results set the basis for a larger study to refine TLB serum score and move closer to the clinical application of TLB providing useful information to the gastroenterologist during patient diagnosis.

278 Assessing effects of lateral tilt on cardiac output using a Non-invasive technique

2021 ◽  
Vol 224 (2) ◽  
pp. S182-S183
Author(s):  
Zaid Diken ◽  
Antonio F. Saad ◽  
Sema Hajmurad ◽  
Rakesh Vadhera ◽  
Michelle Simon ◽  
...  
Keyword(s):  
Cardiac Output ◽  
Invasive Technique ◽  
Lateral Tilt ◽  
Non Invasive

Non-invasive methods in the assessment of portal hypertension severity

2021 ◽  
Vol 75 (2) ◽  
pp. 125-133
Author(s):  
Soňa Franková ◽  
Jan Šperl
Keyword(s):  
Portal Hypertension ◽  
Liver Fibrosis ◽  
Shear Wave ◽  
Transient Elastography ◽  
Venous Pressure ◽  
Liver Stiffness ◽  
Invasive Technique ◽  
Hepatic Veins ◽  
Oesophageal Varices ◽  
Non Invasive

Portal hypertension represents a wide spectrum of complications of chronic liver diseases and may present by ascites, oesophageal varices, splenomegaly, hypersplenism, hepatorenal and hepatopulmonary syndrome or portopulmonary hypertension. Portal hypertension and its severity predicts the patient‘s prognosis: as an invasive technique, the portosystemic gradient (HPVG – hepatic venous pressure gradient) measurement by hepatic veins catheterisation has remained the gold standard of its assessment. A reliable, non-invasive method to assess the severity of portal hypertension is of paramount importance; the patients with clinically significant portal hypertension have a high risk of variceal bleeding and higher mortality. Recently, non-invasive methods enabling the assessment of liver stiffness have been introduced into clinical practice in hepatology. Not only may these methods substitute for liver biopsy, but they may also be used to assess the degree of liver fibrosis and predict the severity of portal hypertension. Nowadays, we can use the quantitative elastography (transient elastography, point shear-wave elastrography, 2D-shear-wave elastography) or magnetic resonance imaging. We may also assess the severity of portal hypertension based on the non-invasive markers of liver fibrosis (i.e. ELF test) or estimate clinically signifi cant portal hypertension using composite scores (LSPS – liver spleen stiff ness score), based on liver stiffness value, spleen diameter and platelet count. Spleen stiffness measurement is a new method that needs further prospective studies. The review describes current possibilities of the non-invasive assessment of portal hypertension and its severity.

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