scholarly journals Genetic polymorphism of opioid receptors and use of opioid substances by high school students of Cotonou and Parakou (Benin)

2021 ◽  
Vol 9 (3) ◽  
pp. 136-144
Author(s):  
Arnaud Coffi AGBANLINSOU ◽  
Razack OSSENI ◽  
Marius O ADJAGBA ◽  
Ferdinand ADOUNPKE ◽  
Odile A KOUGBLENOU ◽  
...  

In Benin, schools become sometimes the hub for dealing and consuming psychoactive substances; opioids in particular. The objectives of this study are to identify the risk factors related to the use of opioids and investigate the genetic polymorphism of mu and delta opioid receptors of teenagers and young adults who consume opioids in schools. To accomplish this, 453 students participated in this study; R diversity 3.6.1 software in the RStudio environment was used to identify students who experience opioids through ASSIST V3.0 scoring. SNPs A118G on the OPRM gene (µ) and T921C on the OPRD gene (d), were searched by PCR on DNA extracts from peripheral blood of individuals. We identified 54 regular opioid users and 399 non users. This experience begins for most with the consumption of alcohol and tobacco and is facilitated by the proximity of marshlands, kiosks, and pubs near high schools and colleges. The aggressive advertisement combined with relative socio-cultural tolerance just worsen this behavioral deviance. We found no difference in the SNP frequencies of the OPRM (µ) and OPRD (d) genes between students opioids consumers and non-consumers.

2021 ◽  
pp. 105984052098753
Author(s):  
Sung Hae Kim ◽  
Yoona Choi

Although the rate of sexual intercourse among adolescents has increased in Asian countries, including Korea, many sexually active adolescents still do not use contraception. The aim of this study was to identify the risk factors for contraceptive nonuse among adolescents using decision tree analysis of the 2018 Korea Youth Risk Behavior Survey data from 2,460 high school students who had an experience of sexual intercourse. The findings indicated that the highest risk group who did not use contraception during sexual intercourse did not receive sexual health education in school and was involved in habitual or purposeful drug use. The experience of ever receiving treatment due to violence and the experience of sexual intercourse after drinking were also identified as risk factors for contraceptive nonuse. To encourage contraceptive use, development of standard sexual health education, counseling, and educational intervention intended to prevent risky behaviors is needed.


2005 ◽  
Vol 36 (2) ◽  
pp. 133-137 ◽  
Author(s):  
Cunxian Jia ◽  
Zhongtang Zhao ◽  
Qigui Bo ◽  
Ying Zhang ◽  
Zhaolan Liu

2001 ◽  
Vol 41 (2) ◽  
pp. 111
Author(s):  
Dewi Iriani ◽  
Alan R. Tumbelaka ◽  
Sri Sudaryati Nasar

Iron deficiency anemia (IDA) is a serious significant public health problem, since it’s negative impact on physicaland psycological development, behavior and work capacity. There are many risk factors influencing the development of IDA.A cross-sectional study has been conducted in 301 Junior High School students at East Jakarta in January-February 2000.A structural questionnaire, physical, cell blood count (CBC) and Serum Iron ( SI ) examinations were performed. We foundsome of the many variables were connected with IDA by using bivariat analysis. Anemia was found in 41 out of 301 students(13,6%) and only 25 children (8.3%) suffered from IDA. Among 179 female students, only 33 children (18.5%) were anemicand 20 out of 33 (12.0%) have IDA. Bivariat analysis revealed a significant association between IDA with sex, parent’seducation, food frequency questionnaire (FFQ) scores, and menstruation. It is concluded that the prevalence of IDA in thisstudy was lower than found in some previous studies in Indonesia. Gender, menstruation, low educated parents, and low FFQscores were risk factors for IDA.


2017 ◽  
Vol 87 (9) ◽  
pp. 696-704 ◽  
Author(s):  
Elizabeth M. Parker ◽  
Sarah Lindstrom Johnson ◽  
Katrina J. Debnam ◽  
Adam J. Milam ◽  
Catherine P. Bradshaw

Author(s):  
Philip Mathew ◽  
Indiradevi ER ◽  
Soniya UR ◽  
Shilpa Poonnen ◽  
Sajan Alex ◽  
...  

2020 ◽  
Author(s):  
Shao Chia Chiu Lin ◽  
Mei-Ju Chen

Abstract Background: The effects of different definitions for metabolic syndrome (MetS) on its prevalence were examined, and the differences in the discriminatory power, as well as the optimal cutoff points of relevant risk factors, were analyzed in this study. Methods: 45,756 health checkup data sets from 2011 to 2014 of high school students aged between 15 to 17 years were sourced in Taipei city. The database included the students’ gender, age, height, weight, waist circumference (WC), systolic and diastolic blood pressure, as well as biochemical markers such as triglycerides (TG), high-density lipoprotein cholesterol, and fasting glucose (FG) levels. The ROC curve statistical approach was used to analyze the discriminatory power and optimal cutoff points of the relevant MetS risk factors. Results: The prevalence of MetS among adolescents in Taipei was 2.3% and 1.2%, according to the criteria of the modified National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) and the International Diabetes Federation (IDF) respectively. The prevalence increased to 4.3% when this study’s criteria were used. Among the components of MetS analyzed, WC and TG had stronger discriminatory powers, while FG had the weakest. The optimal cutoff point for WC was approximately the 90 th percentile, while that for the TG was similar to the criteria of the modified NCEP ATP III. About 44.6% of adolescents had at least one MetS component. Body mass index also had good discriminatory power. Conclusions: The prevalence of MetS differs depending on the diagnostic criteria used. Redefining the cutoff points for the components of MetS in adolescents in different regions, as well as further screening and intervention, are crucial to prevent cardiovascular disease and type 2 diabetes mellitus in the future.


Author(s):  
Kritika Poudel ◽  
Naomi Sumi

Providing information on increased cancer risks associated with certain behaviors might encourage adolescents to initiate protective behaviors. This study firstly determined the knowledge of risk factors and prevention of cervical cancer. Secondly, it checked an association between mothers’ screening practice and student’s knowledge. A descriptive, cross sectional study was conducted among 253 pairs of high school students and their mothers. Knowledge on cervical cancer was significantly lower among students and mothers. While cancer screening tests, maintenance of hygiene were considered as major preventive measures for cervical cancer, human papilloma vaccine was the least considered preventive measure. Students who were female, attended discussions on cancer and had a healthy diet had better awareness of cancer. Mothers of female students had better knowledge about cervical cancer than mothers of male students. Less perceived susceptibility and lack of knowledge were major obstacles among mothers, limiting cervical cancer screening to 15%. Although association between knowledge of students and screening practice of mothers was not clear, it was observed that cancer communication increased awareness of cervical cancer in both groups. Our findings showed a strong need for school-based cancer education program to address the issues of human papillomavirus vaccinations, cervical cancer risk and screening.


2003 ◽  
Vol 37 (3) ◽  
pp. 351-356 ◽  
Author(s):  
Frida M Fischer ◽  
Ignez S Martins ◽  
Denize C Oliveira ◽  
Liliane R Teixeira ◽  
Maria do Rosario D Latorre ◽  
...  

OBJECTIVES: To estimate the prevalence of occupational injuries and identify their risk factors among students in two municipalities. METHODS: A cross-sectional survey was conducted in public schools of the municipalities of Santo Antonio do Pinhal and Monteiro Lobato, Brazil. A stratified probabilistic sample was drawn from public middle and high schools of the study municipalities. A total of 781 students aged 11 to 19 years participated in the study. Students attending middle and high school answered a comprehensive questionnaire on living and working conditions, as well as aspects of work injuries, and health conditions. Multiple logistic regression models were fitted to estimate risk factors of previous and present occupational injuries. RESULTS: Of 781 students, 604 previously had or currently have jobs and 47% reported previous injuries. Among current workers (n=555), 38% reported injuries on their current job. Risk factors for work injuries with statistically significant odds ratio >2.0 included attending evening school, working as a housekeeper, waiter or brickmaker, and with potentially dangerous machines. CONCLUSIONS: The study results reinforce the need of restricting adolescent work and support communities to implement social promotion programs.


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