scholarly journals Comparison of Chemical Element Contents in Thyroid Goiter, Adenoma, and Thyroiditis investigated using Neutron Activation Analysis

2021 ◽  
Vol 12 (3) ◽  
pp. 098-107
Author(s):  
Vladimir Zaichick
Keyword(s):  
Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
Chemical Elements ◽  
Thyroid Tissue ◽  
Therapeutic Interventions ◽  
Endocrine Gland ◽  
Clear Understanding ◽  
Tissue Samples ◽  
Normal Thyroid

Thyroid benign nodules (TBNs) are the most common lesions of this endocrine gland. Among TBNs the colloid goiter (CG), thyroiditis (T), and thyroid adenoma (TA) are the most frequent diseases. An evaluation of the variant of TBNs is clinically important for subsequent therapeutic interventions, as well as for more clear understanding the etiology of these disorders. The aim of this exploratory study was to examine differences in the content of bromine (Br), calcium (Ca), chlorine (Cl), iodine (I), potassium (K), magnesium (Mg), manganese (Mn), and sodium (Na) in tissues of CG, TA, and T. Thyroid tissue levels of eight chemical elements (ChE) were prospectively evaluated in 46 patients with CG, 19 patients with TA, and 12 patients with T. Measurements were performed using non-destructive instrumental neutron activation analysis with high resolution spectrometry of short-lived radionuclides. Tissue samples were divided into two portions. One was used for morphological study while the other was intended for ChE analysis. It was observed that in CG, TA and T tissues content of Br was significantly higher, while level of I was lower than in normal thyroid tissue. I accumulation in T tissue was lower than in normal thyroid and CG. Abnormal increase in Br level and decrease in I level in all TBNs might demonstrate an involvement of these ChE in etiology and pathogenesis of TBNs. It was suosed that great losses of I in thyroid with T, in contract to little reduced levels of I content in thyroid with CG and TA, could possibly be explored for differencial diagnosis of T.

scholarly journals Determination of twenty chemical element contents in normal and goitrous thyroid using X-ray fluorescent and neutron activation analysis

2021 ◽  
Vol 11 (2) ◽  
pp. 130-146
Author(s):  
Vladimir Zaichick
Keyword(s):  
Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
Chemical Elements ◽  
Thyroid Tissue ◽  
Nodular Goiter ◽  
Tissue Samples ◽  
X Ray ◽  
Important Health ◽  
Non Destructive

Nodular goiter (NG) is an internationally important health problem. The aim of this exploratory study was to examine the content of silver (Ag), bromine (Br), calcium (Ca), chlorine (Cl), cobalt (Co), chromium (Cr), cooper (Cu), iron (Fe), mercury (Hg), iodine (I), potassium (K), magnesium (Mg), manganese (Mn), sodium (Na), rubidium (Rb), ammonium (Sb), scandium (Sc), selenium (Se), strontium (Sr), and zinc (Zn) in the normal thyroid and in the thyroid tissues with diagnosed colloid NG.. Thyroid tissue levels of twenty chemical elements (ChE) were prospectively evaluated in 46 patients with NG and 105 healthy inhabitants. Measurements were performed using non-destructive energy-dispersive X-Ray fluorescent analysis combined with instrumental neutron activation analysis with high resolution spectrometry of short– and long-lived radionuclides. Tissue samples were divided into two portions. One was used for morphological study while the other was intended for ChE analysis. It was found that during a goitrous transformation the levels of Ag, Br, Cl, Co, Cu, Fe, Hg, Mg, Na, and Sc in thyroid tissue significantly increased, whereas the levels of I and Sr decrease. It was supposed that the changes in levels Ag, Br, Cl, Co, Cu, Fe, Hg, I, Mg, Na, Sc, and Sr in thyroid tissue can be used as NG markers.

scholarly journals THE POSSIBLE ROLE OF TRACE ELEMENTS IN THYROID HYPERTROPHIC AND ADENOMATOUS TRANSFORMATION

2022 ◽  
Author(s):  
Vladimir Zaichick
Keyword(s):  
Trace Elements ◽  
Peer Review ◽  
Inductively Coupled Plasma ◽  
Chemical Elements ◽  
Thyroid Tissue ◽  
Therapeutic Interventions ◽  
Endocrine Gland ◽  
Normal Thyroid Tissue ◽  
Tissue Samples ◽  
Normal Thyroid

Background: Thyroid benign nodules (TBNs) are the most common diseases of this endocrine gland and are common worldwide. Among TBNs the colloid goiter (CG) and thyroid adenoma (TA) are very frequentdiseases. Evaluation of variant of TBNs is clinically important for subsequent therapeutic interventions, as well as for a clearer understanding the etiology of these disorders. The aim of this exploratory study was to examine differences in the content offifty trace elements (TE) in CG and TA tissues. Methods: Thyroid tissue levels of TE have prospectively evaluated in 46 patients with CG and 19 patients with TA. Measurements have performed using a combination of non-destructive and destructive methods: instrumental neutron activation analysis with high resolution spectrometry of long-lived radionuclides (INAA-LLR) and inductively coupled plasma mass spectrometry (ICPMS), respectively. Tissue samples were divided into two portions. One was used for morphological study while the other was intended for TE analysis. Results: It was observed that in both CG and TA tissues the contents of Ag, Al, Cr, Hg, Mn, Th, and Zn increased, whereas the levels of Au, Be, Cs, Pb, Rb, Sb, Sc, Th, Yb, and Zr were unchanged in comparison with normal thyroid tissue. No differences were found between the TE contents of CG and TA. Conclusions: From results obtained, it was possible to conclude that the common characteristics of CG and TA tissue samples were of a high level of Ag, Al, Cr, Hg, Mn, Th, and Zn in comparison with normal thyroid and, therefore, these TE could be involved in etiology and pathogenesis of thyroid disorders such as CG and TA.                    Peer Review History: Received: 12 November 2021; Revised: 15 December; Accepted: 31 December, Available online: 15 January 2022 Academic Editor: Ahmad Najib, Universitas Muslim Indonesia,  Indonesia, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.  Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 6.5/10 Average Peer review marks at publication stage: 7.5/10 Reviewers: Prof. Dr. Hassan A.H. Al-Shamahy, Sana'a University, Yemen, [email protected] Rima Benatoui, Laboratory of Applied Neuroendocrinology, Department of Biology, Faculty of Science, Badji Mokhtar University Annaba, BP12 E L Hadjar–Algeria, [email protected] Similar Articles: COMPARISON OF LEVELS OF TWENTY CHEMICAL ELEMENTS IN NORMAL THYROID TISSUE AND HYPERTROPHIC THYROID TISSUE

Trace Element Contents in Thyroid Cancer Investigated by Instrumental Neutron Activation Analysis

2018 ◽  
Vol 1 (1) ◽  
pp. 1-13
Keyword(s):  
Thyroid Cancer ◽  
Neutron Activation Analysis ◽  
Instrumental Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
Trace Element ◽  
Thyroid Tissue ◽  
Tissue Levels ◽  
Trace Element Contents ◽  
Element Contents

Background: Thyroid cancer is an internationally important health problem. The aim of this exploratory study was to evaluate whether significant changes in the thyroid tissue levels of Ag, Co, Cr, Fe, Hg, Rb, Sb, Sc, Se, and Zn exist in the malignantly transformed thyroid. Methods: Thyroid tissue levels of ten trace elements were prospectively evaluated in 41 patients with thyroid malignant tumors and 105 healthy inhabitants. Measurements were performed using non-destructive instrumental neutron activation analysis with high resolution spectrometry of long-lived radionuclides. Tissue samples were divided into two portions. One was used for morphological study while the other was intended for trace element analysis. Results: It was found that contents of Ag, Co, Cr, Hg, and Rb were significantly higher (approximately 12.8, 1.4, 1.6, 19.6, and 1.7 times, respectively) in cancerous tissues than in normal tissues. Conclusions: There are considerable changes in trace element contents in the malignantly transformed tissue of thyroid.

Neutron activation analysis of bald eagle feathers: analytical precision and sources of sampling variation

1985 ◽  
Vol 63 (12) ◽  
pp. 2707-2718 ◽  
Author(s):  
Gary R. Bortolotti ◽  
Jon C. Barlow
Keyword(s):  
Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
Chemical Elements ◽  
The Body ◽  
Bald Eagle ◽  
Haliaeetus Leucocephalus ◽  
Bald Eagles ◽  
Chemical Profiles ◽  
Significant Patterns

Instrumental neutron activation analysis was used to investigate the feather chemistry of wild and captive bald eagles (Haliaeetus leucocephalus). This paper documents variation that may be attributable to method of feather collection, laundering of samples, and precision of the analysis, as well as the variability within and among feathers from different locations on the body of individual birds. For most samples, reliable estimates could be made of the concentrations of bromine, magnesium. manganese, sodium, vanadium, aluminum, chlorine, calcium, and sulphur. Iodine and copper were detected but could not be measured precisely. There were highly significant patterns of variation along the length of a single feather for most chemical elements. The vane and calamus portions of feathers differed in chemical composition and the concentrations of the elements in the two parts were not correlated. Feathers belonging to the same molt but collected several months apart had similar chemical profiles. Variation within an individual feather and among feathers from different parts of the body necessitates rigorous consistency in the method of sampling feathers. Possible explanations for the observed patterns of elemental composition are discussed.

Determination of chemical elements in magnesium-based materials by neutron activation analysis

2021 ◽  
Vol 9 (1A) ◽  
Author(s):  
Caio Almeida Justino Silva ◽  
Lilian Ninoska Muriel Braguin ◽  
Jesualdo Luiz Rossi ◽  
Isolda Costa ◽  
Mitiko Saiki
Keyword(s):  
Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
Chemical Elements

Instrumental neutron activation analysis of Marrubium vulgare L., a valuable medicinal herb

2016 ◽  
Vol 104 (4) ◽  
Author(s):  
Bouzid Nedjimi ◽  
Brahim Beladel
Keyword(s):  
Neutron Activation Analysis ◽  
Instrumental Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
Chemical Elements ◽  
Medicinal Herb ◽  
Marrubium Vulgare ◽  
Instrumental Neutron Activation

AbstractTwenty two chemical elements were identified by Instrumental neutron activation analysis in

Corn Cultivation for Silage: Evaluation of Elemental Composition in the Soil and Plants by Neutron Activation Analysis

2019 ◽  
pp. 1-9
Author(s):  
Wellington Ferrari Da Silva ◽  
Maria Ângela de B. C. Menezes ◽  
Douglas José Marques
Keyword(s):  
Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
Neutron Flux ◽  
Technology Development ◽  
Chemical Elements ◽  
Radioactive Isotopes ◽  
Flux Monitor ◽  
Agricultural Pesticides ◽  
Adequate Management

Corn cultivation for silage requires special soil management and constant applications of fertilizers and agricultural pesticides to achieve satisfactory yield levels. This study was carried out on a farm that has grown corn for several years. The soil does not have adequate management in terms of fertility and fertilization. The matrices collected were soil, roots, leaves and grains in a corn silage area to investigate which chemical elements are present and their concentrations. The neutron activation analysis (NAA) by k0-standardization method was applied on elemental concentration determination. In this technique, the sample is submitted to a neutron flux, in order to produce radioactive isotopes of the nuclei present in the original sample. In the k0 method, the sample is irradiated together with a neutron flux monitor, usually gold (Au), in the same irradiation position and standards of the interested element are not necessary. Several samples can be irradiated simultaneously when stacked inside the irradiation vessel, intercalated with neutron flux monitors. The irradiations were carried out in the TRIGA MARK I IPR-R1 research reactor at Nuclear Technology Development Centre/Brazilian Commission for Nuclear Energy (CDTN / CNEN). In the analysis, As, Ba, Br, Ca, Ce, Co, Cr, Cs, Cu, Eu, Fe, Hf, K, La, Mo, Na, Nd, Rb, Sb, Sc, Sm, Ta, Tb, Th, U, Yb and Zn were identified in the samples. Although the site studied lacks adequate management of soil fertility and fertilization, Ca, Cu, K, Mo and Zn were determined and their presences are important because they are essential for corn development. Adequate content for the cultivation of silage corn were verified by assessing these nutrients and their translocation in the plant.

scholarly journals Determination of the Elemental Composition of Aromatic Plants Cultivated Industrially in the Republic of Moldova Using Neutron Activation Analysis

Agronomy ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1011
Author(s):  
Alexandru Ciocarlan ◽  
Gergana Hristozova ◽  
Aculina Aricu ◽  
Ion Dragalin ◽  
Inga Zinicovscaia ◽  
...  
Keyword(s):  
Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
Chemical Elements ◽  
Major And Trace Elements ◽  
Human Consumption ◽  
Anethum Graveolens ◽  
Transfer Coefficients ◽  
Mineral Contents ◽  
The Republic

The mineral contents of roots, leaves, stalks, and inflorescences of the aromatic plant species Anethum graveolens L., Coriandrum sativum L., Lavandula angustifolia Mill., Levisticum officinale W.D.J. Koch, and Salvia sclarea L. were studied by means of neutron activation analysis. The contents of 36 major and trace elements were determined and biological transfer coefficients were calculated. Among major and minor elements, K with a content in the range of 9230–59,600 mg/kg and Fe in the range of 69–3420 mg/kg were the most abundant elements in the studied plants. The content of the toxicant As ranged between 0.14–0.79 mg/kg; however, in the leaves (1.3 mg/kg) and inflorescences (1.0 mg/kg) of L. angustifolia there was found to be about 1 mg/kg, equal to the guideline maximal level recommended for food by the WHO. By comparing the data to Markert’s Reference Plant, “chemical fingerprints” were identified for each species. High contents of the elements Al, Hf, Se, Sc, Na, Ta, Th were determined in all studied plants. Collocated soil samples from the cultivation field were analyzed to calculate the biological accumulation coefficients for 35 of the elements determined in the plants. Considering the levels of chemical elements, the medicinal herb samples investigated are considered as relatively safe for human consumption.

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