Relationship Between Adenosine Deaminase with Ectopic Pregnancy in Pregnant Women Referred to Motahari Hospital in Urmia (2017-2018)

Aim of the current research is to assess the Chlamydia Trachomatis infection role in the development of early pregnancy complication including ectopic pregnancy and miscarriage in Sulaimanyia Maternity Teaching Hospital. It is a comparative study conducted in Gynecology Clinic and Emergency department of Sulaimanyia Maternity Teaching Hospital during the period from 1st of September 2018 to 31st of March 2019. The study groups included of 70 pregnant women; the first group included 35 ectopic pregnant women and the second group included 35 normal pregnant women that both groups had been selected randomly. Pregnant women with history of ectopic pregnancies, women used intrauterine device, in vitro fertilization, assisted reproduction and history of pelvic surgery. Blood sample (2 ml venous blood) collected to test for antibodies level for Chlamydia Trachomatis by Alegria test system for both studied groups and patients with ectopic pregnancy detected by beta human chorionic gonadotropin and ultrasound scanning. The collected data analyzed by SPSS program and for compare between means of two variables independent sample t-test was used while for comparison of categorical variables Chi square test was used with considering ≤ 0.05 P-value as significant level. The results shows that the mean age of normal pregnancy were (28.3±4.6) group compared with mean age ectopic pregnancy (29.5±4.9) group. The mean IgG (6.3±5.1) of patients with ectopic pregnancy was found to be significantly higher than mean IgG (2.8±1.1) for normal pregnant patients (P-value 0.01) and IgM mean (4.5±2.4) of patients with ectopic pregnancy was significantly higher than mean IgM (1.6±1.2) for normal pregnant patients with P-value 0.01. In conclusion, infection of Chlamydia Trachomatis has a significant relationship with the development of ectopic pregnancy therefor screening and treatment of Chlamydia infection may reduce ectopic pregnancy rate with low cost

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Measurement of IgG antibodies to Chlamydia trachomatis by commercial enzyme immunoassays and immunofluorescence in sera from pregnant women and patients with infertility, pelvic inflammatory disease, ectopic pregnancy, and laboratory diagnosed Chlamydia psittaci/Chlamydia pneumoniae infection

Journal of Clinical Pathology ◽

10.1136/jcp.56.3.225 ◽

2003 ◽

Vol 56 (3) ◽

pp. 225-229 ◽

Cited By ~ 16

Author(s):

C S Jones

Keyword(s):

Chlamydia Trachomatis ◽

Pregnant Women ◽

Ectopic Pregnancy ◽

Pelvic Inflammatory Disease ◽

Inflammatory Disease ◽

Chlamydia Pneumoniae ◽

Chlamydia Psittaci ◽

Igg Antibodies ◽

Commercial Enzyme ◽

Enzyme Immunoassays

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TINJAUAN KASUS KEHAMILAN EKTOPIK DI BLU RSUP PROF. Dr. R. D. KANDOU MANADO PERIODE 1 JANUARI 2010 – 31 DESEMBER 2011

Jurnal e-Biomedik ◽

10.35790/ebm.1.1.2013.1159 ◽

2013 ◽

Vol 1 (1) ◽

Author(s):

Sri Cynthia D. Logor ◽

Freddy W. Wagey ◽

Maria F.T. Loho

Keyword(s):

Retrospective Study ◽

Early Detection ◽

Pregnant Women ◽

Ectopic Pregnancy ◽

Frequency Distribution ◽

Endometrial Cavity ◽

Life Threatening ◽

History Of

Abstract: An ectopic pregnancy is a pregnancy with a fertilized ovum, implant and grow in a normal endometrial cavity in the uteri. When pregnancy is experiencing a process of termination (abortion) is called a rupture dectopic pregnancy (KET). This study aims to determine umtuk review cases of ectopic pregnancy in BLU Dr Prof. Dr. R. D. Kandou period 1 January 2010 - 31 December 2011 in terms of age, parity,history of abortion ,historyofcontraceptive/familyplanningacceptors. This is a descriptive retrospective study. The population in this study were all patients who were treated at the department of Obstetrics Gynecology Prof. BLU. Dr. R. D. Kandou Period January 1, 2010 - December 31, 2011. The data has been processed and then presented in the form of frequency distribution table and further discussed base don’t heresultsobtained. Conclusion: The results of this study indicate the amount and presentation of the study variables based on the total number of cases. It is recommended that the mother has since given a case of ectopic pregnancy can be life-threatening emergency, then at the age of susceptible pregnant women ectopic pregnancy is recommended for early detection. Keywords: ectopic pregnancy Abstrak: Kehamilan ektopik adalah kehamilan dengan ovum yang dibuahi berimplantasi dan tumbuh tidak di tempat yang normal yakni dalam endometrium kavum uteri. Bila kehamilan tersebut mengalami proses pengakhiran (abortus) maka disebut dengan kehamilan ektopik terganggu (KET). Penelitian ini bertujuan umtuk mengetahui tinjauan kasus kehamilan ektopik di BLU RSUP Prof. Dr. R. D. Kandou Periode 1 Januari 2010 – 31 Desember 2011 ditinjau dari umur, paritas, riwayat abortus, riwayat pemakaian kontrasepsi/akseptor KB. Penelitian ini bersifat deskriptif retrospektif. Populasi dalam penelitian ini adalah seluruh pasien yang dirawat di bagian Obstetri Ginekologi BLU RSUP Prof. Dr. R. D. Kandou Periode 1 Januari 2010 – 31 Desember 2011. Data yang diolah kemudian disajikan dalam bentuk tabel distribusi frekuensi dan selanjutnya di bahas berdasarkan hasil yang diperoleh. Simpulan: Hasil penelitian ini menunjukkan jumlah dan presentasi dari variabel penelitian berdasarkan jumlah keseluruhan kasus yang terjadi. Disarankan bagi para ibu karena mengingat kehamilan ektopik merupakan kasus darurat yang dapat mengancam nyawa, maka pada wanita hamil usia rentan kehamilan ektopik disarankan untuk melakukan deteksi dini. Kata Kunci: kehamilan ektopik

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Determinants of ectopic pregnancy among pregnant women attending referral hospitals in Southwestern parts of Oromia regional state, Southwest Ethiopia: A multi-center case control study

10.21203/rs.2.21551/v1 ◽

2020 ◽

Author(s):

Urge Gerema ◽

Tilahun Alemayehu ◽

Getachew Chane ◽

Diliab Desta ◽

Amenu Diriba

Keyword(s):

Pregnant Women ◽

Ectopic Pregnancy ◽

Prior History ◽

Transmitted Infection ◽

Sexual Transmitted Infection ◽

Southwest Ethiopia ◽

Regional State ◽

Induced Abortions ◽

Referral Hospitals ◽

History Of

Abstract Background: Ectopic pregnancy is an abnormal condition in which implantation of the blastocyst occurs outside the endometrium of the uterus. It is gynecological important, particularly in the developing world, because of the associated enormous rate of high morbidity, during the first trimester of pregnancy. A better understanding of its risk factors can help to prevent its prevalence. However, the determinants of ectopic pregnancy are not well understood and few researches conducted in our country were based on secondary data covering small scale area. Objective: This study aimed to identify determinants of ectopic pregnancy among pregnant women attending referral hospitals in Southwestern part of Oromia regional state, Southwest Ethiopia. Methods: Hospital based case control study was employed from June 1 to September 30, 2019. The study was conducted in five referral hospitals in Southwestern part of Oromia regional state. 59 cases and 118 controls were sampled. Data were entered by using Epidata version 3.1 and analyzed using SPSS version 23. Descriptive statistics were used to explore the data. All explanatory variables with p -value of <0.25 in bi-variable analysis, then entered into multivariable logistic regression. Associated factors were identified at 95% confidence interval (p <0.05). Results : One hundred seventy-four pregnant women (58 cases and 116 controls) were participating in the study. Prior two or more induced abortions [AOR=3.95:95% CI: 1.22-13.05], previous history of caesarean section [AOR=3.4:95% CI: 1.11-10.94], marital status (being single) [AOR=4.04:95%CI: 1.23-13.21], reporting prior recurrent sexual transmitted infection [AOR=2.25:95%CI: 1.00-5.51], prior history of tubal surgery [AOR= 3.32:95%CI: 1.09-10.13] , were more likely to have an ectopic pregnancy with their respective AOR with 95%CI. Conclusion and Recommendation: It was found that having a history of more than two induced abortions during previous pregnancies, marital status (single) , recurrent Sexual transmitted infection, prior history of tubal surgery and experiencing prior caesarean section were found to be determinants of ectopic pregnancy. Hospitals should give emphasis on prevention and early detection of risks of ectopic pregnancy and create awareness in order to reduce the burden of ectopic pregnancy.

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Miscarriage on Endometriosis and Adenomyosis in Women by Assisted Reproductive Technology or with Spontaneous Conception: A Systematic Review and Meta-Analysis

BioMed Research International ◽

10.1155/2020/4381346 ◽

2020 ◽

Vol 2020 ◽

pp. 1-19

Author(s):

Yangxue Huang ◽

Xianhong Zhao ◽

Yiyuan Chen ◽

Jie Wang ◽

Weilin Zheng ◽

...

Keyword(s):

Preterm Birth ◽

Gestational Diabetes ◽

Pregnant Women ◽

Ectopic Pregnancy ◽

Assisted Reproductive Technology ◽

Low Birthweight ◽

Placental Abruption ◽

Reproductive Technology ◽

Placenta Praevia ◽

Spontaneous Conception

Background. In the past several years, there has been an increasing concern on miscarriage caused by endometriosis or adenomyosis. However, the results reported by different studies remain controversial. The present study is aimed at assessing the impact of endometriosis and adenomyosis on miscarriage. Materials and Methods. Searches were carried out in PubMed, Embase, and the Cochrane library for studies published from inception until February 29, 2020. The investigators included studies that evaluated miscarriage risk in pregnant women with endometriosis or adenomyosis by assisted reproductive technology (ART), or with spontaneous conception (SC). Miscarriage (<28 weeks) was the primary outcome. The secondary outcomes were antepartum hemorrhage (APH), postpartum hemorrhage (PPH), preterm birth, low birthweight, placenta praevia, placental abruption, ectopic pregnancy, stillbirth, gestational diabetes, preeclampsia, and intrauterine growth restriction (IUGR). Endnote was used for the study collection, and the data analyses were carried out by two authors using Review Manager version 5.2. Results. Thirty-nine studies, which is comprised of 697,984 women, were included in the present study. Miscarriage risk increased in women with endometriosis in SC (OR: 1.81, 95% CI: 1.44-2.28, I 2 = 96 % ) compared with those without endometriosis, while women with endometriosis who underwent ART had a similar miscarriage risk, when compared to those with tubal infertility (OR: 1.03, 95% CI: 0.92-1.14, I 2 = 0 % ). Compared with those without adenomyosis, women with adenomyosis had an augmented miscarriage risk in ART (OR: 2.81, 95% CI: 1.44-5.47, I 2 = 64 % ). Compared with those without endometriosis, women with endometriosis had higher odds of APH, PPH, preterm birth, stillbirth, and placenta praevia. No difference was observed in the incidence of ectopic pregnancy, placental abruption, pre-eclampsia, gestational diabetes, low birthweight, and IUGR. Conclusion. Women with endometriosis had an augmented miscarriage risk in SC and a similar miscarriage risk during ART. Adenomyosis was associated with miscarriage in pregnant women using ART.

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ASUHAN KEBIDANAN PADA NY. T USIA 28 TAHUN P1A2 POST CURETTAGE ATAS INDIKASI KEHAMILAN EKTOPIK TERGANGGU DENGAN TINDAKAN LAPAROTOMI DI RUMAH SAKIT SANTA ELIS

Elisabeth Health Jurnal ◽

10.52317/ehj.v3i1.231 ◽

2018 ◽

Vol 3 (1) ◽

pp. 28-37

Author(s):

Lismawati . ◽

Ria Oktaviance

Keyword(s):

Maternal Mortality ◽

Pregnant Women ◽

Ectopic Pregnancy ◽

Final Report ◽

Midwifery Care ◽

Study Approach ◽

High Prevalence ◽

Life Threatening ◽

Ectopic Pregnancies

Ectopic pregnancies are impaired including high-risk pregnancies that can be marked by either spotting or moderate bleeding that can be life-threatening to the mother. Based on worldwide WHO research, there is a maternal mortality of 500,000 lives per year and infant mortality in particular 10 million neonates per year. More than 60% of ectopic pregnancies occur in women aged 20-30 with low socio-economic and live in areas with high prevalence ofgonorrhea and tuberculosis prevalence. In Indonesia the maternal mortality rate is 330/100,000 live births. Maternal mortality is estimated at about 16,500-17,500 per year. One-third of them are due to falling-out services.Goals : Performing a Craving Care in Pregnant Women Mrs.T Age 28 years old G3P1A1 with Disturbed Ectopic Pregnancy using a seven step Varney approachMethods:Using descriptive method with case study approach implemented by author through approach of midwifery management. The case observed by the author in this Final Report is Mrs. T Age 28 years G3P1A1 with Disturbed Ectopic Pregnancy at Saint Elizabeth Hospital Medan Year 2018.Results: Gain real experience on the implementation of Midwifery care in pregnant women with Disturbed Ectopic Pregnancy at Saint Elizabeth Hospital Medan. Implementation of midwifery care in pregnant women with Disturbed Ectopic Pregnancy at Saint Elizabeth Hospital Medan is in accordance with the existing theory and hope can be used as input by students so as to provide broad insight into the quality of midwifery services according to midwifery care.Conclution : Standards through the approach of midwifery care management in pregnant women with Disturbed Ectopic Pregnancy.

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Benzodiazepine Use Before Conception and Risk of Ectopic Pregnancy

International Journal for Population Data Science ◽

10.23889/ijpds.v5i5.1434 ◽

2020 ◽

Vol 5 (5) ◽

Author(s):

Elizabeth Wall-Wieler ◽

Thalia K Robakis ◽

Deirdre J Lyell ◽

Reem Masarwa ◽

Robert W Platt ◽

...

Keyword(s):

Pregnant Women ◽

Ectopic Pregnancy ◽

Health Care Providers ◽

Group Analysis ◽

Care Providers ◽

Relative Risks ◽

Increased Risk ◽

Benzodiazepine Use ◽

Using Data ◽

Ectopic Pregnancies

IntroductionEctopic pregnancy occurs in 1% to 2% of the all recognized pregnancies, yet half of women who have an ectopic pregnancy do not have any known risk factors. A potential but unstudied risk factor for ectopic pregnancy is benzodiazepine use, which could affect muscle contraction in the fallopian tube. Objectives and ApproachWe compared the risk of ectopic pregnancy among women with and women without benzodiazepine prescriptions before conception. using data from United States commercial insurance claims (IBM® MarketScan® Databases). We performed a cohort study of 1,691,366 pregnancies between November 1, 2008 and September 30, 2015, and used unadjusted and inverse probability of treatment (IPT) weighted log-binomial models to calculate relative risks (RR) of ectopic pregnancy for pregnant women who did and did not fill any prescriptions for benzodiazepines in the 90 days before conception. Sub-group analysis was conducted on women who had anxiety and women who had insomnia diagnoses in the year before conception. ResultsOf the 1,691,366 pregnant women, 1.06% filled at least two benzodiazepine prescriptions in the 90 days before conception. Among women with a benzodiazepine prescription, there was an excess of 80 ectopic pregnancies per 10,000 pregnancies, and their IPT-weighted risk of ectopic pregnancies was 1.47 (95% CI 1.32 to 1.63) times greater relative to women without benzodiazepine prescriptions before conception. The IPT-weighted RR between ectopic pregnancy and benzodiazepine use was 1.34 (95% CI 1.18 to 1.53) among women with anxiety disorder diagnoses and 1.28 (95% CI 0.99 to 1.68) among women with an insomnia diagnosis. Conclusion / ImplicationsThis study found that women who have a benzodiazepine prescription before conception are at an increased risk of ectopic pregnancy. This information can help women and their health care providers make more fully informed decisions about benzodiazepine use in their reproductive years.

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