scholarly journals Complex clinical and echographic assessment of the peculiarities of developmental anomalies of uterus and vagina in children and adolescents

2020 ◽  
Vol 5 ◽  
pp. 37-41
Author(s):  
A. P. Sadoviy
Keyword(s):  
Children And Adolescents ◽  
Information Content ◽  
Clinical Examination ◽  
Clinical Symptoms ◽  
Practical Importance ◽  
Diagnostic Errors ◽  
The State ◽  
Ultrasound Screening ◽  
Gynecological Examination ◽  
Internal Genitalia

The objective. To assess the structure of independent and combined forms of anomalies in the development of the uterus and/or vagina in children and adolescents, justifying the need for ultrasound screening in this age group.Materials and methods. The study involved 146 patients with malformations of the uterus and/or vagina at the age from 10 to 20 years. All patients underwent a clinical examination, which included anamnestic data, gynecological examination, and ultrasound examination. The calculation of indicators of the diagnostic information content of ultrasound was carried out taking into account the sensitivity, specificity and accuracy of the method.Results. In the course of the study, it was found that the largest proportion of all anomalies of the internal genitals was uterine malformations (37,0%), complete doubling of the uterus and vagina (17,1%), vaginal aplasia (15,1%). Genetic or chromosomal pathology was detected in 36 patients (24,7%), in the remaining 110 patients (75,3%) a multifactorial nature of the disease was assumed.Attention is drawn to the fact that 48 patients (32.8%) with uterine and/or vaginal malformations, who did not present complaints, were identified during the primary ultrasound screening, which indicates the effectiveness of this method in examining girls and adolescents. In 12 children (8,25%) in addition to abnormalities in the development of the uterus and/or vagina, ultrasound revealed tumors and tumor-like diseases of the uterine appendages. Also, 57 malformations of other organs and systems were revealed in 49 (33,6%) examined patients, and 8 (5,5%) had concomitant defects. In most cases, in 99 patients (67,8%) with anomalies in the development of internal genitalia, the anamnesis was aggravated by the factors of their parents (burdened heredity, disease, occupational health, etc.)Conclusion. As a result of a comprehensive clinical examination of patients with congenital anomalies in the development of internal genitalia, the diagnosis was clarified, the share of hereditary and some environmental factors in the manifestation of this pathology was revealed, which is one of the common gynecological diseases that are characterized by a variety of forms of anomalies, clinical symptoms and a high percentage of diagnostic errors. At puberty, the use of echography to clarify the state of the internal genital organs is of great practical importance. Non-invasiveness, absence of psychogenic traumatization, safety and high information content make it possible not only to diagnose congenital pathology, but also to use this method as a dynamic observation of the state of the uterus and/or vagina in girls and adolescents, which is very important when choosing rational methods for correcting this pathology

Clinical Symptoms of Oncological Diseases at Incurable Children and Adolescents

2016 ◽  
Vol 3 (1) ◽  
pp. 48-53 ◽  
Author(s):  
Yu.A. Punanov ◽  
◽  
S.A. Safonova ◽  
I.G. Venchikova ◽  
S.I. Minchenko ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Clinical Symptoms ◽  
Oncological Diseases

scholarly journals The research of the state of prosthetic bed tissues in patients with pemphigus vulgaris.

2017 ◽  
Vol 23 (1) ◽  
Author(s):  
Bohdan Lyubomyrovych Henyk ◽  
Mykola Mykhaylovych Rozko
Keyword(s):  
Survey Data ◽  
Oral Mucosa ◽  
Clinical Examination ◽  
Comparative Evaluation ◽  
Objective Assessment ◽  
Pemphigus Vulgaris ◽  
The State ◽  
Control Group

The clinical examination of condition of tissues prosthetic bed was conducted in 20 patients with  pemphigus vulgaris. The results are compared with survey data of 20 persons of control group without somatic pathology. It was conducted the analyzes of subjective and objective assessment of tissues prosthetic bed, the results of clinical examination and frequency of various pathologies of the oral mucosa membrane in the studied groups, conducted the comparative evaluation of dental indicators.

scholarly journals The results of clinical examination of patients with decompensated form of dental abrasion and complaints of the state of the temporomandibular joints

2020 ◽  
Vol 20 (1-2) ◽  
pp. 80-84
Author(s):  
Rustem R. Gabdrafikov
Keyword(s):  
Clinical Examination ◽  
The State ◽  
Old Patients ◽  
Temporomandibular Joints

We examined 66 patients 1755 years old with decompensated form of dental abrasion, who had applied to the hospital Dental Forte with various types of complaints of discomfort in the TMJ. They were divided into several groups: 1st 1725 years old, 2nd 2535 years old, 3rd 3545 years old, 4th 4555 years old patients. It was established, that the age of 2535 is specific for significant indication of dysfunctions in the TMJ. By the age of 3545 years the number of complaints of discomfort in the TMJ increases. There is also increase in the diversity of complaints, and decrease in their allocation in percentage terms. The number of complaints and their diversity in patients of 4555 years old remained, complaints of one type of pain decreased, but the number of complaints about pain associated with chewing, headache, crunch, etc. increased.

scholarly journals La protección de los niños, niñas y adolescentes con discapacidad: deudas pendientes / The protection of childrens and adolescent with disabilities: pending debts

2018 ◽  
pp. 67-80
Author(s):  
Sofía Puccio
Keyword(s):  
Children And Adolescents ◽  
The State ◽  
The Face

El presente trabajo tiene por objeto analizar la protección de los niños, niñas y adolescentes con discapacidad y cuáles son las deudas pendientes al respecto. El Estado se ha instituido como el primer garante en materia de salud y de protección de la discapacidad, pero muchas veces los ciudadanos deben someterse a un constante peregrinaje frente a los rechazos de las debidas prestaciones.   The purpose of this paper is to analyze the protection of children and adolescents with disabilities and what are the outstanding debts in this regard. The State has established itself as the first guarantor in matters of health and disability protection, but many times citizens must submit to a constant pilgrimage in the face of rejections of due benefits.

scholarly journals Алгоритм доклинической диагностики сахарного диабета 1-го типа как основа для создания Реестра ДААт-позитивных детей и подростков Украины с прогнозированным развитием заболевания

2019 ◽  
Vol 24 (3) ◽  
pp. 203-216
Author(s):  
M.D. Tron’ko ◽  
K.P. Zak ◽  
V.V. Popova
Keyword(s):  
Type 1 Diabetes ◽  
Children And Adolescents ◽  
Pancreatic Beta Cells ◽  
State Institution ◽  
Tolerance Test ◽  
The State ◽  
Immunological Study ◽  
C Peptide ◽  
Study Results

Aim — The establishment of mechanisms for T1D development at early and late preclinical stages of disease formation in children and adolescents. Material and methods. At the State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism of NAMS of Ukraine» mentioned the Program «Immunity in the preclinical period of T1D development» was initiated, on the basis of which the Register of marker-positive children with predictable development of type 1 diabetes was created, which includes 612 children aged from 7 to 15 years with burdened heredity, in which the titer of diabetes-associated autobodies (DAA), cytokines, levels of basal and postprandial glycemia and secretion of C-peptide at preclinical and clinical stages of T1D development in children and adolescents based on the performed clinical and immunological study. Results. The new data have been obtained at the State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism of NAMS of Ukraine», which allowed to substantially supplement the existing ideas about the type 1 diabetes (T1D) pathogenesis. As a result of the performed study, a group of marker-positive children with burdened heredity and a predicted risk of developing the disease was formed. It was found that an increased titer of DAA was observed in 162 (35.45%) of 457 children with burdened heredity with no less than two times determination of DAA presence in them, mainly GADA and IA‑2A, the clinical debut was manifested in 86 (53.08%) of them from 6 months to 16 years (27.4±4.3 months). The formula of combined occurrence and values of simultaneously increased DAA titers to islet autoantigens, namely IA‑2A + GADA, was determined, which is a predictor of both the duration of preclinical stage of T1D development and the debut rate. Impaired cytokine production (increase of the level of proinflammatory cytokines IL‑1α, IL‑6 and TNFα, IL‑8 and IL‑16 while reducing the concentration of IL‑4 in the PB) as key factors of the T1D pathogenesis, which determine the rate of T1D debut, and the aggressiveness of its course were also established. It was found that the early preclinical period of T1D development in DAA+ children was characterized by the presence of dysglycemia in the form of increased glycemia in 2 hour after the glucose tolerance test and a slight decrease in secretion of stimulated C-peptide; in addition, dysglycemia in the form of impaired fasting glycemia was added in DAA+children in the late preclinical period, and a decrease in both basal and stimulated secretion of the C-peptide was determined, indicating that the potential of pancreatic beta cells was depleted.

scholarly journals Forced Oscillation Technique for Monitoring the Respiratory Status of Children with Cystic Fibrosis: A Systematic Review

Children ◽  
2021 ◽  
Vol 8 (10) ◽  
pp. 857
Author(s):  
Ioanna Loukou ◽  
Maria Moustaki ◽  
Agni Deligianni ◽  
Olympia Sardeli ◽  
Konstantinos Douros
Keyword(s):  
Cystic Fibrosis ◽  
Lung Function ◽  
Children And Adolescents ◽  
Forced Oscillation ◽  
Clinical Symptoms ◽  
Current Evidence ◽  
Forced Oscillation Technique ◽  
Gold Standard Method ◽  
Respiratory Status ◽  
Alternative Modality

Spirometry is considered the gold standard method for monitoring lung function of patients with cystic fibrosis (CF) but it requires patients’ cooperation and therefore it is not useful for the majority of preschool-aged children. Oscillometry is an alternative modality for lung function monitoring that requires minimal cooperation and can be applied in children as young as 3 years of age. Furthermore, it generates lesser aerosol compared to spirometry, an issue that is of considerable importance in the COVID-19 era. The aim of this review was to present the existing clinical data regarding the application of oscillometry in children and adolescents with CF. The method seems to have acceptable feasibility and repeatability. However, there is conflicting data regarding the correlation of oscillometry values with the clinical symptoms of CF patients either in clinically stable or in exacerbation periods. Furthermore, it is not clear to what extent oscillometry measurements correlate with the spirometry indices. Based on current evidence, spirometry cannot be substituted by oscillometry in the monitoring of the respiratory status of children and adolescents with CF.

scholarly journals Should We Continue to Screen for Developmental Dysplasia of the Hip in Clubfoot? Our Experience and Review of the Literature

2021 ◽  
Vol 7 (2) ◽  
Keyword(s):  
Clinical Examination ◽  
Hip Dysplasia ◽  
Screening Programme ◽  
Developmental Dysplasia ◽  
The Other ◽  
Idiopathic Clubfoot ◽  
Ultrasound Screening ◽  
Review Of The Literature ◽  
Targeted Ultrasound ◽  
Dysplasia Of The Hip

Objective: The association between clubfoot and developmental dysplasia of the hip (DDH) remains uncertain, with only a few studies linking both. However, clubfoot is considered as a risk factor for DDH. The aim of this study was to determine the incidence of DDH and evaluate the need for routine hip imaging in our population of children with clubfoot. Methods: Retrospective analysis of all patients treated for clubfoot in our center between 2010 and 2019. We included patients with hip imaging for DDH in the first 12 months of life. Results: There were 108 children with clubfoot who underwent DDH screening. 92 had idiopathic clubfoot and 16 had syndromic clubfoot. Of the patients with idiopathic clubfoot, 2 (2.2%) had DDH; one had a clinically unstable hip and the other patient underwent hip screening on account of the clubfoot alone. Among patients with syndromic clubfoot, 3 (18.8%) had developmental dysplasia of the hip. Two of them had an abnormal hip examination while the other had normal hip clinical examination but other established risk factors for DDH. Conclusion: A targeted ultrasound or radiological screening programme for DDH in idiopathic clubfoot diagnosed hip dysplasia in only 1 child that would have otherwise been missed by clinical examination alone. We conclude that hip imaging is not warranted in children with idiopathic clubfoot and regular clinical screening may suffice. In syndromic clubfoot, due to the higher incidence of DDH, we recommend specific ultrasound screening even in the presence of a normal hip examination. Keywords: Clubfoot, Screening, Developmental dysplasia of the hip.

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