STRUKTUR DAN FUNGSI MITOS KERAJAAN RAJA AMPAT

2018 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
Insum Malawat
Keyword(s):  
Structure And Function ◽  
Pragmatic Approach ◽  
Story Structure ◽  
Cultural Symbol ◽  
Concrete Form ◽  
Contemporary Life ◽  
And Function

<p>Myth as a research object can be studied from different angles. Quantity of study greatly determines the quality of the story. The concrete form of learning folklore is done by reusing the hidden values in it to see its relevance to contemporary life. Various means of literature used in a story is in order to function mengkistalkan meaning or message to be conveyed. This shows the urgency and significance of a cultural symbol in the mythical text as the entity’s identity.</p><p>This paper applies to the structure and function of the Maya mythology of Raja Ampat Regency full of Raja Ampat Kingdom Myth (MKRA). The depiction of the story structure is structured according to elements of Lucian Goldmann’s worldview. Meanwhile, the description of Bastian and Mitchel’s functions and culture through a pragmatic approach.</p>

scholarly journals Inclusive Design: Systems Interaction Society - Textile Means of Rehabilitation - Child

2020 ◽  
Vol 6 (1) ◽  
pp. 198-206
Author(s):  
A. Golubchikova ◽  
N. Korobtseva
Keyword(s):  
Quality Of Life ◽  
Children With Disabilities ◽  
Emotional State ◽  
Structure And Function ◽  
The Body ◽  
Basic Principles ◽  
External Appearance ◽  
Design Systems ◽  
And Function

One of the goals of rehabilitation of children with disabilities (HHS) is to improve their quality of life. For this purpose, various technical means, devices and adaptations which solve a number of problems in life of the child are developed. But there is another aspect that affects the quality of life of such children — is the attitude of people around them. The child is emotionally unstable individual, his psyche is very vulnerable to react to negative emotions. In this case the saying that ‘meet on clothes’ is very applicable. And if the child looks aesthetically pleasing, then others perceive him positively. But in some diseases (physical deviations from the norm) there is no ergonomic and aesthetic clothing. The paper considers the interaction of the systems Society — Textile means of rehabilitation — Child. It is revealed that textile means of rehabilitation, including inclusive clothing have an impact not only on the child’s condition, but also on the emotional state of the society in contact with him, especially his parents. Research on the systematization of information about violations of the structure and function of the body allowed to identify and group the possible causes of violations of the proportions of the child’s body. Some can be compensated by the use of fixing products, others through the use of illusions that contribute to the visual alignment of the proportions of the child. The article formulates the basic principles of designing textile means of rehabilitation and inclusive clothing for children with disabilities, aimed at harmonizing the perception of the external appearance of the child.

scholarly journals dom2vec: Capturing domain structure and function using self-supervision on protein domain architectures

2020 ◽  
Author(s):  
Damianos P. Melidis ◽  
Brandon Malone ◽  
Wolfgang Nejdl
Keyword(s):  
Domain Structure ◽  
Language Processing ◽  
Performance Comparison ◽  
Structure And Function ◽  
Protein Domain ◽  
Linguistic Features ◽  
Enzymatic Function ◽  
Protein Prediction ◽  
And Function

Abstract Background: Word embedding approaches have revolutionized natural language processing (NLP) research. These approaches aim to map words to a low-dimensional vector space, in which words with similar linguistic features cluster together. Embedding-based methods have also been developed for proteins, where words are amino acids and sentences are proteins. The learned embeddings have been evaluated qualitatively, via visual inspection of the embedding space and extrinsically, via performance comparison on downstream protein prediction tasks. However, these sequence embeddings have the caveat that biological metadata do not exist for each amino acid, in order to measure the quality of each unique learned embedding vector. Results: Here, we present dom2vec, an approach for learning protein domain embeddings using word2vec on InterPro annotations. In contrast to sequence embeddings, biological metadata do exist for protein domains, related to each domain separately. Therefore, we present four intrinsic evaluation strategies to quantitatively assess the quality of the learned embedding space. To perform a reliable evaluation in terms of biology knowledge, we selected the metadata related to the most distinctive biological characteristics of domains. These are the structure, enzymatic and molecular function of a given domain. Notably, dom2vec obtains adequate level of performance in the intrinsic assessment, therefore we can draw an analogy between the local linguistic features in natural languages and the domain structure and function information in domain architectures. Moreover, we demonstrate the dom2vec applicability on protein prediction tasks, by comparing it with state-of-the-art sequence embeddings in three downstream tasks. We show that dom2vec outperform sequence embeddings for toxin and enzymatic function prediction and is comparable with sequence embeddings in cellular location prediction. Conclusions: We report that the application of word2vec on InterPro annotations produces domain embeddings with two significant advantages over sequence embeddings. First, each unique dom2vec vector can be quantitatively evaluated towards its available structure and function metadata. Second, the produced embeddings can outperform the sequence embeddings for a subset of downstream tasks. Overall, dom2vec embeddings are able to capture the most important biological properties of domains and surpass sequence embeddings for a subset of prediction tasks.

scholarly journals Kids’ Outcomes And Long-term Abilities (KOALA): protocol for a prospective, longitudinal cohort study of mild traumatic brain injury in children 6 months to 6 years of age

BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e040603 ◽  
Author(s):  
Miriam H Beauchamp ◽  
Fanny Dégeilh ◽  
Keith Yeates ◽  
Isabelle Gagnon ◽  
Ken Tang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Traumatic Brain Injury ◽  
Cohort Study ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Structure And Function ◽  
Brain Structure And Function ◽  
And Function

IntroductionMild traumatic brain injury (mTBI) is highly prevalent, especially in children under 6 years. However, little research focuses on the consequences of mTBI early in development. The objective of the Kids’ Outcomes And Long-term Abilities (KOALA) study is to document the impact of early mTBI on children’s motor, cognitive, social and behavioural functioning, as well as on quality of life, stress, sleep and brain integrity.Methods and analysesKOALA is a prospective, multicentre, longitudinal cohort study of children aged 6 months to 6 years at the time of injury/recruitment. Children who sustain mTBI (n=150) or an orthopaedic injury (n=75) will be recruited from three paediatric emergency departments (PEDs), and compared with typically developing children (community controls, n=75). A comprehensive battery of prognostic and outcome measures will be collected in the PED, at 10 days, 1, 3 and 12 months postinjury. Biological measures, including measures of brain structure and function (magnetic resonance imaging, MRI), stress (hair cortisol), sleep (actigraphy) and genetics (saliva), will complement direct testing of function using developmental and neuropsychological measures and parent questionnaires. Group comparisons and predictive models will test the a priori hypotheses that, compared with children from the community or with orthopaedic injuries, children with mTBI will (1) display more postconcussive symptoms and exhibit poorer motor, cognitive, social and behavioural functioning; (2) show evidence of altered brain structure and function, poorer sleep and higher levels of stress hormones. A combination of child, injury, socioenvironmental and psychobiological factors are expected to predict behaviour and quality of life at 1, 3 and 12 months postinjury.Ethics and disseminationThe KOALA study is approved by the Sainte-Justine University Hospital, McGill University Health Centre and University of Calgary Conjoint Health Research Ethics Boards. Parents of participants will provide written consent. Dissemination will occur through peer-reviewed journals and an integrated knowledge translation plan.

scholarly journals Fuzzy Based Adaptive Anisotropic Diffusion Despeckling Filter

2019 ◽  
Vol 9 (2) ◽  
pp. 2519-2522
Keyword(s):  
Anisotropic Diffusion ◽  
Multiplicative Noise ◽  
Ultrasound Image ◽  
Visual Quality ◽  
Speckle Noise ◽  
Structure And Function ◽  
Diffusion Filter ◽  
Anisotropic Diffusion Filter ◽  
And Function

Echocardiography is an ultrasound of the heart for the assessment of cardiac structure and function. Images obtained from the ultrasound suffer from a speckle Noise. Speckle is an inherent multiplicative noise which affects the visual perception by discriminating the fine details in the echocardiography. Speckle removal is important step to improve the visual quality of the echocardiography for better diagnosis. Anisotropic diffusion is one of the popular techniques to despeckle the ultrasound image in recent times. In this paper, we propose a fuzzy based adaptive anisotropic diffusion despeckling filter to despeckle echocardiography ultrasound image. The results show that fuzzy diffusion when combined with adaptive anisotropic diffusion filter gives better performance compared with existing despeckling filters

scholarly journals HEART AND AGE (PART II): CLINICAL MANIFESTATIONS OF AGEING

2013 ◽  
Vol 12 (4) ◽  
pp. 86-90 ◽  
Author(s):  
D. U. Akasheva ◽  
E. V. Plokhova ◽  
I. D. Strazhesko ◽  
E. N. Dudinskaya ◽  
O. N. Tkacheva
Keyword(s):  
Clinical Manifestations ◽  
The Elderly ◽  
Structure And Function ◽  
Disease Development ◽  
Cardiac Structure ◽  
Age Related ◽  
High Prevalence ◽  
Cardiac Structure And Function ◽  
And Function

Ageing is an inevitable process which affects quality of life and reduces life expectancy. Age-related cardiac changes reduce compensatory reserves of the heart and accelerate the disease development. Such changes in cardiac structure and function, observed in the absence of cardiovascular disease (CVD), are considered age-related. However, taking into account the high prevalence of CVD in the elderly, it is problematic to define the genuine cardiac ageing. This review discusses a range of subclinical cardiac conditions which are common in older people. 

Histopathological analysis of the gills of fresh water fish Channa gachua exposed to fungicide Pydiflumetofen

2020 ◽  
pp. 32-35
Author(s):  
Shweta Pallavi
Keyword(s):  
Structure And Function ◽  
Histopathological Analysis ◽  
Fresh Water Fish ◽  
Chemical Quality ◽  
Fish Gill ◽  
Quality Of Water ◽  
Secondary Lamellae ◽  
Water Fish ◽  
And Function

Indiscriminate use of pesticides has become a serious problem among human and ambient environment. The present study is aimed to assess the damage caused to the fish Channa gachua (family: Channidae) exposed to fungicide Pydiflumetofen. Respiration in Channa gachua mainly occurs through their gills. Any change in the chemical quality of water directly affects the structure and function of gills. Fish gill also helps in osmoregulation and excretion besides respiration. When fish exposed to sub-lethal concentration of Pydiflumetofen pesticide for 10 days, 15days and 20days include Curling and fusion in secondary lamellae, Hyperplasia, reduction in the respiratory surface area of filaments, fusion at the tip of the lamellae, sub lamellar and sub epithelial space occur.

Long-Term Results of Surgically Treated Radial Polydactyly – An Outcome Correlation Study

2019 ◽  
Vol 24 (03) ◽  
pp. 264-269
Author(s):  
Ching Man Yeung ◽  
Alexander Kai Yiu Choi ◽  
Jennifer Wing Sze Tong ◽  
Winnie Fok ◽  
Yat Fai Chan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Surgical Treatment ◽  
Well Being ◽  
Structure And Function ◽  
Long Term Results ◽  
Activity Restriction ◽  
Patient Reported ◽  
And Function

Background: Thumb polydactyly is one of the commonest congenital hand differences. Traditional surgeon-based outcome scores capture outcomes mainly on bodily structure and function. Outcomes on the long-term well-being of the patients in the domains of activity and participation are not fully studied. Methods: Forty-eight thumbs in forty-five Chinese patients with radial polydactyly underwent surgical treatment at or before 3 years old were recruited. Mean follow-up was 11.6 years. Surgical outcomes were collected and compared to the normal opposite thumb. The results were compiled into the Japanese Society for Surgery of the Hand (JSSH) score, Cheng score and Tada score. Patients’ activity involving hands were assessed by both objective tools and patient-reported outcome measure while their health-related quality of life (HRQoL) was assessed by Patient- and Parent-reported Pediatric Quality of Life Inventory (PedsQL). Correlations between outcomes were analysed. Results: Overall, both parents and patients themselves reported good quality of life with mean score of 86.6% and 92.1% respectively in PedsQL. The combined surgical scores ranged from 52% good or excellent results using JSSH score to 100% good result using Cheng score. None of the outcomes on bodily structure and function showed positive correlation with patient’s well-being. Negative correlation was noted in total passive range of movement, active movement and Cheng score. All patients reported no activity restriction. Writing test did not show significant slowing. The operated hands had significantly poorer fine motor dexterity than normal. No significant correlation is noted between activity outcomes and PedsQL. Conclusions: Outcomes on bodily structure, function and activity showed little correlation with patients’ well-being after thumb polydactyly correction. It should be careful in using or analysing patient/parent-reported outcome measures on HRQoL as outcome assessment of surgical treatment of radial polydactyly.

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