scholarly journals Fertile window and biophysical biomarkers of cervical secretion in subfertile cycles: a look at biotechnology applied to NaProTechnology

2022 ◽  
Vol 49 (1) ◽  
pp. 1
Author(s):  
José María Murcia Lora ◽  
Oscar Martínez Martínez ◽  
Jennifer Simoni ◽  
Marian Martínez Calvo ◽  
Alberto Falces de Andrés ◽  
...  
2012 ◽  
Vol 382 (1-2) ◽  
pp. 211-215 ◽  
Author(s):  
Morgan A. Marks ◽  
Yolanda Eby ◽  
Roslyn Howard ◽  
Patti E. Gravitt

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
L Worsfold ◽  
L Marriott ◽  
S Johnson ◽  
J Harper

Abstract Study question Are period trackers giving women accurate information about their periods and ovulation? Summary answer The top 10 period trackers gave conflicting information on period dates, ovulation day and the fertile window. What is known already Period tracking applications allow women to track their menstrual cycles and receive a prediction for their periods. The majority of applications also provide predictions of day of ovulation and the fertile window. Previous research indicates applications are basing predictions on assuming women undergo a textbook 28-day cycle with ovulation occurring on day 14 and a fertile window between days 10 and 17. Study design, size, duration An audit of menstrual cycle apps was conducted on the Apple app store using menstrual cycle tracker/period tracker as the search terms. The top ten apps that followed the inclusion and exclusion criteria were analysed and used for this study. All apps had the ability to allow retrospective data entry giving future cycle predictions and fertile window, and nine of the apps predicted a day of ovulation. Participants/materials, setting, methods Five women’s profiles for 6 menstrual cycles were created and entered into each app. Cycle length (CL) and ovulation day (OD) for the 6th cycle were; Woman 1 – Constant 28 day CL, 0D 16, Woman 2 – Average 23 day CL, OD 13, Woman 3 – Average 28 day CL, OD 17, Woman 4 – Average 33 day CL, OD 20 and Woman 5 – Irregular, average 31 day CL, OD 14. Main results and the role of chance For cycle length, the apps all predicted woman 1’s cycles correctly but for women 2–5, the apps predicted 0 to 8 days shorter or longer than expected. For day of ovulation; for woman 1, no apps predicted this correctly; the apps ranged from day 13–15. For woman 2, 1 app was correct and overall the apps showed a lot of variation from day 8 to 13. For woman 3, no apps got it right, with a range of day 13–16. For woman 4, 2 apps got it right, but the apps ranged from day 13–20. For woman 5, no apps got right; the apps ranged from day 13–21. Irrespective of cycle length, 7 apps predicted a fertile window of 7 days in almost all cases; except 1 app that predicted 6 days for woman 2 and a different app which predicted 8 days for woman 4. For the remaining 3 apps, one always predicted a 10 day fertile window. One app predicted an 11 day fertile window in 4/5 women. One app predicted a 12 day fertile window in 4/5 women. Limitations, reasons for caution The five profiles created spanned a range of observed cycle characteristics, but many permutations are possible. A Monte Carlo type analysis could be conducted to examine these possibilities to provide more precise assessment of app performance, but as data had to be added manually into apps, this was not possible. Wider implications of the findings: The apps do not use the same algorithm and show variation. The information given by these apps is not 100% accurate, especially for the day of ovulation and the fertile window which can only be predicted if using a marker of ovulation, such as basal body temperature or ovulation sticks. Trial registration number Not applicable


Author(s):  
Justin C. Konje ◽  
Oladipo A. Ladipo

Central to the survival of any species is the ability to procreate. In most cases, procreation is sexual, involving a process that ensures appropriate and timed contact between the male and female gametes. Successful human reproduction is premised on sexual intercourse occurring at a time when there is a receptive endometrium as well as an ovum ready for fertilization by spermatozoa. This time window of the menstrual cycle known as the fertile or fecund window is poorly defined and highly variable from one individual to another. Furthermore, while spermatogenesis is a continuous process, the impact of too frequent intercourse (defined as that occurring more than every 2 to 3 days) on fertilization has often been thought to be associated with a decreased fertilization potential of spermatozoa. Current evidence challenges previously held views on the fertile window and how it is determined, the timing of intercourse and how it is related to conception and miscarriages, the length of the luteal phase, and the precise time period during which the chances of fertilization are highest in any given menstrual cycle. The ability of spermatozoa to survive in the female genital tract for 5 days means fertilization can occur up to 5 days from sexual intercourse. During each menstrual cycle, there is a window of 5 to 6 days for fertilization to occur, and this period is defined not by the length of the cycle but by the timing of ovulation, with the chances of fertilization highest with intercourse occurring 1 to 2 days before ovulation.


10.2196/13404 ◽  
2019 ◽  
Vol 21 (4) ◽  
pp. e13404 ◽  
Author(s):  
Brianna Mae Goodale ◽  
Mohaned Shilaih ◽  
Lisa Falco ◽  
Franziska Dammeier ◽  
Györgyi Hamvas ◽  
...  

2019 ◽  
Vol 112 (3) ◽  
pp. e268
Author(s):  
Evangelia Mouriki ◽  
Aljosa Bilic ◽  
Brianna M. Goodale ◽  
Gyorgyi Hamvas ◽  
Catrin Argyle ◽  
...  

2015 ◽  
Vol 103 (5) ◽  
pp. 1319-1325.e3 ◽  
Author(s):  
Rene Ecochard ◽  
Olivia Duterque ◽  
Rene Leiva ◽  
Thomas Bouchard ◽  
Pilar Vigil
Keyword(s):  

Author(s):  
A. J. R. White ◽  
B. W. Chappell

ABSTRACTS-type granites have properties that are a result of their derivation from sedimentary source rocks. Slightly more than half of the granites exposed in the Lachlan Fold Belt of southeastern Australia are of this type. These S-type rocks occur in all environments ranging from an association with migmatites and high grade regional metamorphic rocks, through an occurrence as large batholiths, to those occurring as related volcanic rocks. The association with high grade metamorphic rocks is uncommon. Most of the S-type granites were derived from deeper parts of the crust and emplaced at higher levels; hence their study provides insights into the nature of that deeper crust. Only source rocks that contain enough of the granite-forming elements (Si, Al, Na and K) to provide substantial quantities of melt can produce magmas and there is therefore a fertile window in the composition of these sedimentary rocks corresponding to feldspathic greywacke, from which granite magmas may be formed.In this paper, three contrasting S-type granite suites of the Lachlan Fold Belt are discussed. Firstly, the Cooma Granodiorite occurs within a regional metamorphic complex and is associated with migmatites. It has isotopic and chemical features matching those of the widespread Ordovician sediments that occur in the fold belt. Secondly, the S-type granites of the Bullenbalong Suite are found as voluminous contact-aureole and subvolcanic granites, with volcanic equivalents. These granites are all cordierite-bearing and have low Na2O, CaO and Sr, high Ni, strongly negative εNd and high 87Sr/86Sr, all indicative of S-type character. However, the values of these parameters are not as extreme as for the Cooma Granodiorite. Evidence is discussed to show that these granites were derived from a less mature, unexposed, deeper and older sedimentary source. Other hypotheses such as basalt mixing are discussed and can be ruled out. The Strathbogie Suite granites are more felsic but all are cordierite-bearing and have chemical and other features indicative of an immature sedimentary source. They are closely associated with cordierite-bearing volcanic rocks. The more felsic nature of the suite results in part from crystal fractionation. It is suggested that the magma may have entered this “crystal fractionation” stage of evolution because it was a slightly higher temperature magma produced from an even less mature sediment than the Bullenbalong Suite. The production of these S-type magmas is discussed in terms of vapour-absent melting of metagreywackes involving both muscovite and biotite. The production of a magma in this way is consistent with the low H2O contents and geological setting of S-type granites and volcanic rocks in the Lachlan Fold Belt.


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