Cross-validation of pedometer-determined cut-points for healthy weight in British children from White and South Asian backgrounds

Background:The purpose of this study was to cross-validate international BMI-referenced steps/d cut points for US girls (12,000 steps/d) and boys (15,000 steps/d) 6 to 12 years of age.Methods:Secondary pedometer-determined physical activity data from US children (N = 1067; 633 girls and 434 boys, 6 to 12 years) were analyzed. Using international BMI classifications, cross-validation of the 12,000 and 15,000 steps/d cut points was examined by the classification precision, sensitivity, and specificity for each age–sex stratum.Results:For girls (boys) 6 to 12 years, the 12,000 (15,000) steps/d cut points correctly classified 42% to 60% (38% to 67%) as meeting (achieved steps/d cut point and healthy weight) and failing (did not achieve steps/d cut point and overweight). Sensitivity ranged from 55% to 85% (64% to 100%); specificity ranged from 23% to 62% (19% to 50%).Conclusion:The utility of pedometer steps/d cut points was minimal in this sample given their inability to differentiate among children who failed to achieve the recommended steps/d and exhibited an unhealthy weight. Caution, therefore, should be used in applying previous steps/d cut points to US children.

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Anthropometric cut-points for discriminating diabetes and the metabolic syndrome among Arabs and Asians: the Kuwait Diabetes Epidemiology Program

British Journal Of Nutrition ◽

10.1017/s0007114521000751 ◽

2021 ◽

pp. 1-11

Author(s):

Victor M. Oguoma ◽

Neil T. Coffee ◽

Saad Alsharrah ◽

Mohamed Abu-Farha ◽

Faisal H. Al-Refaei ◽

...

Keyword(s):

Risk Factors ◽

Metabolic Syndrome ◽

Ethnic Groups ◽

South Asian ◽

International Diabetes Federation ◽

Cvd Risk Factors ◽

Cvd Risk ◽

Data Set ◽

Cut Points ◽

The Metabolic Syndrome

Abstract This study aimed to determine anthropometric cut-points for screening diabetes and the metabolic syndrome (MetS) in Arab and South Asian ethnic groups in Kuwait and to compare the prevalence of the MetS based on the ethnic-specific waist circumference (WC) cut-point and the International Diabetes Federation (IDF) and American Heart Association/National Heart, Lung, and Blood Institute WC criteria. The national population-based survey data set of diabetes and obesity in Kuwait adults aged 18–60 years was analysed. Age-adjusted logistic regression and receiver operating characteristic (ROC) analyses were conducted to evaluate for 3589 individuals the utility of WC, waist:height ratio (WHtR) and BMI to discriminate both diabetes and ≥3 CVD risk factors. Areas under the ROC curve were similar for WC, WHtR and BMI. In Arab men, WC, WHtR and BMI cut-offs for diabetes were 106 cm, 0·55 and 28 kg/m2 and for ≥3 CVD risk factors, 97 cm, 0·55 and 28 kg/m2, respectively. In Arab women, cut-offs for diabetes were 107 cm, 0·65 and 33 kg/m2 and for ≥3 CVD risk factors, 93 cm, 0·60 and 30 kg/m2, respectively. WC cut-offs were higher for South Asian women than men. IDF-based WC cut-offs corresponded to a higher prevalence of the MetS across sex and ethnic groups, compared with Kuwait-specific cut-offs. Any of the assessed anthropometric indices can be used in screening of diabetes and ≥3 CVD risk factors in Kuwaiti Arab and Asian populations. ROC values were similar. The WC threshold for screening the MetS in Kuwaiti Arabs and South Asians is higher for women.

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Objectively-measured sedentary time and physical activity in a bi-ethnic sample of young children: variation by socio-demographic, temporal and perinatal factors

10.21203/rs.2.18426/v2 ◽

2020 ◽

Author(s):

Paul Collings ◽

Sufyan A Dogra ◽

Silvia Costa ◽

Daniel D Bingham ◽

Sally E. Barber

Keyword(s):

Physical Activity ◽

Young Children ◽

South Asian ◽

Sedentary Time ◽

Activity Levels ◽

Light Physical Activity ◽

Asian Children ◽

Physical Activity Levels ◽

Vector Magnitude ◽

British Children

Abstract Background: Evidence suggests that South Asian school-aged children and adults are less active compared to the white British population. It is unknown if this generalises to young children. We aimed to describe variability in levels of physical activity and sedentary time in a bi-ethnic sample of young children from a deprived location. Methods: This observational study included 202 South Asian and 140 white British children aged 1.5 to 5y, who provided 3,181 valid days of triaxial accelerometry (Actigraph GT3X+). Variability in sedentary time and physical activity levels were analysed by linear multilevel modelling. Logistic multilevel regression was used to identify factors associated with physical inactivity (failing to perform ≥180 minutes of total physical activity including ≥60 minutes moderate-to-vigorous physical activity (MVPA) per day). Results: There were no significant ethnic differences in the overall levels of behaviours; South Asian and white British children spent half of daily time sedentary, just over 40% in light physical activity, and the remaining 7.5 to 8% of time in MVPA. Sedentary time was lower and physical activity levels were higher in older children, and levels of MVPA and vector magnitude counts per minute (CPM) were higher on weekends compared to weekdays. In South Asian children, sedentary time was lower on weekends. Sedentary time was lower and physical activity levels were higher in spring compared to winter in white British children, and in all seasons compared to winter in South Asian children. South Asian children born at high birth weight performed more MVPA, and in both ethnicities there was some evidence that children with older mothers were more sedentary and less active. Sedentary time was higher and light physical activity was lower in South Asian children in the highest compared to the lowest income families. South Asian girls performed less MVPA, registered fewer vector magnitude CPM, and were 3.5 times more likely to be physically inactive than South Asian boys. Conclusions: Sedentary time and physical activity levels vary by socio-demographic, temporal and perinatal characteristics in young children from a deprived location. South Asian girls have the most to gain from efforts to increase physical activity levels.

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Qualitative study to identify ethnicity-specific perceptions of and barriers to asthma management in South Asian and White British children with asthma

BMJ Open ◽

10.1136/bmjopen-2018-024545 ◽

2019 ◽

Vol 9 (2) ◽

pp. e024545 ◽

Cited By ~ 2

Author(s):

Monica Lakhanpaul ◽

Lorraine Culley ◽

Tausif Huq ◽

Deborah Bird ◽

Nicky Hudson ◽

...

Keyword(s):

South Asian ◽

Asthma Management ◽

Self Management ◽

Tailored Intervention ◽

Structured Interviews ◽

Positive Role ◽

Asian Children ◽

Children With Asthma ◽

British Children

ObjectiveThis paper draws on the data from the Management and Interventions for Asthma (MIA) study to explore the perceptions and experiences of asthma in British South Asian children using semi-structured interviews. A comparable cohort of White British children was recruited to identify whether any emerging themes were subject to variation between the two groups so that generic and ethnicity-specific themes could be identified for future tailored intervention programmes for South Asian children with asthma.SettingSouth Asian and White British children with asthma took part in semi-structured interviews in Leicester, UK.ParticipantsThirty three South Asian and 14 White British children with asthma and aged 5–12 years were interviewed.ResultsBoth similar and contrasting themes emerged from the semi-structured interviews. Interviews revealed considerable similarities in the experience of asthma between the South Asian and White British children, including the lack of understanding of asthma (often confusing trigger with cause), lack of holistic discussions with healthcare professionals (HCPs), an overall neutral or positive experience of interactions with HCPs, the role of the family in children’s self-management and the positive role of school and friends. Issues pertinent to South Asian children related to a higher likelihood of feeling embarrassed and attributing physical activity to being a trigger for asthma symptoms.ConclusionsThe two ethnicity-specific factors revealed by the interviews are significant in children’s self-management of asthma and therefore, indicate the need for a tailored intervention in South Asian children.

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Cross‐validation of Actigraph derived accelerometer cut‐points for assessment of sedentary behaviour and physical activity in children aged 8‐11 years

Acta Paediatrica ◽

10.1111/apa.15189 ◽

2020 ◽

Vol 109 (9) ◽

pp. 1825-1830 ◽

Cited By ~ 2

Author(s):

Michael J. Duncan ◽

Emma L. J. Eyre ◽

Val Cox ◽

Clare M. P. Roscoe ◽

Mark A. Faghy ◽

...

Keyword(s):

Physical Activity ◽

Sedentary Behaviour ◽

Cross Validation ◽

Cut Points ◽

Accelerometer Cut Points

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G450 An integrated approach using qualitative methods to identify perceptions of asthma in british south asian and white british children

10.1136/archdischild-2018-rcpch.439 ◽

2018 ◽

Author(s):

T Huq ◽

M Lakhanpaul ◽

L Manikam ◽

M Johnson ◽

L Culley ◽

...

Keyword(s):

Qualitative Methods ◽

South Asian ◽

Integrated Approach ◽

British Children

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Objectively-measured sedentary time and physical activity in a bi-ethnic sample of young children: variation by socio-demographic, temporal and perinatal factors

10.21203/rs.2.18426/v1 ◽

2019 ◽

Author(s):

Paul Collings ◽

Sufyan A Dogra ◽

Silvia Costa ◽

Daniel D Bingham ◽

Sally E. Barber

Keyword(s):

Physical Activity ◽

Young Children ◽

South Asian ◽

Sedentary Time ◽

Activity Levels ◽

Light Physical Activity ◽

Asian Children ◽

Physical Activity Levels ◽

Vector Magnitude ◽

British Children

Abstract Background: Evidence suggests that South Asian school-aged children and adults are less active compared to the white British population. It is unknown if this generalises to young children. We aimed to describe variability in levels of physical activity and sedentary time in a bi-ethnic sample of young children from a deprived location.Methods: This observational study included 202 South Asian and 140 white British children aged 1.5 to 5y, who provided 3,181 valid days of triaxial accelerometry. Variability in sedentary time and physical activity levels were analysed by linear multilevel modelling. Logistic multilevel regression was used to identify factors associated with physical inactivity (failing to perform ≥180 minutes of total physical activity including ≥60 minutes moderate-to-vigorous physical activity (MVPA) per day).Results: There were no significant ethnic differences in the overall levels of behaviours; South Asian and white British children spent half of their daily time sedentary, just over 40% in light physical activity, and the remaining 7.5 to 8% of time in MVPA. Sedentary time was lower and physical activity levels were higher in older children, and levels of MVPA and vector magnitude counts per minute (CPM) were higher at weekends compared to weekdays. In South Asian children, sedentary time was lower at weekends. Sedentary time was lower and physical activity levels were higher in spring compared to winter in white British children, and in all seasons compared to winter in South Asian children. South Asian children born at high birth weight performed more MVPA, and in both ethnicities there was some evidence that children with older mothers were more sedentary and less active. Sedentary time was higher and light physical activity was lower in South Asian children in the highest compared to the lowest income families. South Asian girls performed less MVPA, registered fewer vector magnitude CPM, and were 3.5 times more likely to be physically inactive than South Asian boys.Conclusions: Sedentary time and physical activity levels vary by socio-demographic, temporal and perinatal characteristics in young children from a deprived location. South Asian girls have the most to gain from efforts to increase physical activity levels.

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Data-Derived Treatment Duration Goal for Cervical Cancer: Should 8 Weeks Remain the Target in the Era of Concurrent Chemoradiation?

JCO Clinical Cancer Informatics ◽

10.1200/cci.16.00072 ◽

2017 ◽

pp. 1-15 ◽

Cited By ~ 7

Author(s):

Julian C. Hong ◽

Jonathan Foote ◽

Gloria Broadwater ◽

Julie A. Sosa ◽

Stephanie Gaillard ◽

...

Keyword(s):

Cervical Cancer ◽

Treatment Duration ◽

Cross Validation ◽

Recursive Partitioning ◽

Hazard Ratio ◽

Recursive Partitioning Analysis ◽

Rank Test ◽

Cut Points ◽

Cut Point ◽

Lower Stage

Purpose Prior studies have demonstrated the importance of treatment duration (TD) in radiation therapy (RT) for cervical cancer, with an 8-week goal based primarily on RT alone. This study uses a contemporary cohort to estimate the time point by which completion of chemoradiation therapy is most critical. Patients and Methods The National Cancer Database was queried for women with nonmetastatic cervical cancer diagnosed from 2004 to 2012 who underwent chemotherapy, external beam RT, and brachytherapy. Data-derived TD cut points for overall survival (OS) were computed by using recursive partitioning analysis with bootstrapped aggregation (bagging) and 10-fold cross-validation. Models were independently trained with 70% of the population and validated on 30% of the population by log-rank test with and without propensity matching. Multivariable Cox proportional hazards regression was performed for the entire cohort. Results In all, 7,355 women were identified with a median TD of 57 days. Bagged recursive partitioning analysis converged to a mean cut point of 66.6 days (median, 64.5 days; interquartile range, 63.5 to 68.5 days). Cross-validation yielded a cut point of 63.3 days. Both cut points differentiated OS in validation. Younger age, recent diagnosis, geographic region, nongovernment insurance, shorter distance to treatment facility, metropolitan location, lower comorbidity, squamous cell carcinoma, lower stage, negative lymph nodes, and shorter TD were independently associated with longer OS. With adjustment, TD within the mean cut point (64.9 days; hazard ratio, 0.79; 95% CI, 0.73 to 0.87) and 56 days (hazard ratio, 0.87; 95% CI, 0.80 to 0.95) were associated with longer OS. Exploratory stratification suggested increasing OS detriment beyond 64 days. Conclusion Shorter chemoradiation TD in cervical cancer is associated with longer survival, and TD should be minimized as much as possible. The data-derived cut point was distributed around 64 days, with a continuous relationship between shorter TD and longer OS.

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Calibration and Cross-Validation of Accelerometery for Estimating Movement Skills in Children Aged 8–12 Years

Sensors ◽

10.3390/s20102776 ◽

2020 ◽

Vol 20 (10) ◽

pp. 2776 ◽

Cited By ~ 1

Author(s):

Michael J. Duncan ◽

Alexandra Dobell ◽

Mark Noon ◽

Cain C. T. Clark ◽

Clare M. P. Roscoe ◽

...

Keyword(s):

Sedentary Behaviour ◽

Motor Skills ◽

Cross Validation ◽

Moderate Intensity ◽

Roc Curve Analysis ◽

Independent Dataset ◽

Object Control ◽

Cut Points ◽

Accelerometer Cut Points ◽

Children’S Physical Activity

(1) Background: This study sought to calibrate triaxial accelerometery, worn on both wrists, waist and both ankles, during children’s physical activity (PA), with particular attention to object control motor skills performed at a fast and slow cadence, and to cross-validate the accelerometer cut-points derived from the calibration using an independent dataset. (2) Methods: Twenty boys (10.1 ±1.5 years) undertook seven, five-minute bouts of activity lying supine, standing, running (4.5kmph−1) instep passing a football (fast and slow cadence), dribbling a football (fast and slow cadence), whilst wearing five GENEActiv accelerometers on their non-dominant and dominant wrists and ankles and waist. VO2 was assessed concurrently using indirect calorimetry. ROC curve analysis was used to generate cut-points representing sedentary, light and moderate PA. The cut-points were then cross-validated using independent data from 30 children (9.4 ± 1.4 years), who had undertaken similar activities whilst wearing accelerometers and being assessed for VO2. (3) Results: GENEActiv monitors were able to discriminate sedentary activity to an excellent level irrespective of wear location. For moderate PA, discrimination of activity was considered good for monitors placed on the dominant wrist, waist, non-dominant and dominant ankles but fair for the non-dominant wrist. Applying the cut-points to the cross-validation sample indicated that cut-points validated in the calibration were able to successfully discriminate sedentary behaviour and moderate PA to an excellent standard and light PA to a fair standard. (4) Conclusions: Cut-points derived from this calibration demonstrate an excellent ability to discriminate children’s sedentary behaviour and moderate intensity PA comprising motor skill activity.

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