A population-based study of demographical variables and ability to perform activities of daily living in adults with osteogenesis imperfecta

2009 ◽  
Vol 32 (7) ◽  
pp. 579-587 ◽  
Author(s):  
Lena Lande Wekre ◽  
Kathrine Frey Frøslie ◽  
Lena Haugen ◽  
Jan A. Falch
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lena Nilsson ◽  
Christer Andersson ◽  
Rune Sjödahl

Abstract Background During the first pandemic wave, Sweden experienced a high mortality rate. Home healthcare reflects a group of people especially vulnerable to coronavirus disease 2019 (COVID-19). We aimed to evaluate the pattern of comorbidity and frailty in a group of individuals having fatal outcomes in home healthcare during the COVID-19 pandemic March to September 2020, and to assess the contribution of COVID-19 in the fatal outcomes. Methods A cohort of adults with confirmed COVID-19 diagnosis that deceased in home healthcare between March and September 2020 were analysed in a retrospective study comprising home healthcare in 136 facilities in one Swedish county. Main outcome measures were comorbidity and frailty. Results One hundred fifty-five individuals (88 women, 67 men) aged 57–106 (median 88) years were included in the analysis. Nine had considerable frailty (ability to perform various activities of daily living but confined to bed or chair on occasion) and the remaining 146 had severe frailty (unable to perform activities of daily living and/or confined to bed or chair; dementia necessitating care). Three or more diagnoses besides COVID-19 were present in 142 individuals and another eight had two diagnoses in addition to COVID-19. In 20 (13%) individuals, COVID-19 was assessed as the principal cause of death, in 100 (64.5%) a contributing cause, and for the remaining 35 (22.5%) death was probably caused by another comorbidity. This seemed to change over the course of the COVID − 19 pandemic, with its contributing role decreasing from the middle of the summer. Conclusions Death in home healthcare during the first wave of the pandemic mostly affected individuals with severe frailty and comorbidity at very advanced ages. One fifth of the individuals who died in home health care had another cause than Covid-19. Trial registration Clinical Trials.gov NCT04642196 date 24/11/2020.


2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Thomas van Bemmel ◽  
Victoria Delgado ◽  
Jeroen J Bax ◽  
Jacobijn Gussekloo ◽  
Gerard J Blauw ◽  
...  

Author(s):  
Ben Brinkmann ◽  
Justine I Davies ◽  
Miles D Witham ◽  
Guy Harling ◽  
Till Bärnighausen ◽  
...  

Abstract Objectives The importance of impairment in performing Activities of Daily Living (ADL) is likely to increase in sub-Saharan Africa since few care options for affected people exist. This study investigated the prevalence of ADL impairment, the extent to which care-need was met and described characteristics of people with ADL impairment and unmet need in Burkina Faso. Methods This study used data from the CRSN Heidelberg Aging Study, a population-based study among 3,026 adults aged over 40 years conducted in rural Burkina Faso. Information on six basic ADL items was sought, with a follow-up question asking whether care-needs were not met, partially met or met. Bivariable correlations and multivariable logistic regression were used to determine sociodemographic and health characteristics associated with ADL impairment and unmet need. Results ADL impairment of any kind was reported by 1,202 (39.7%) respondents and was associated with older age (Adjusted Odds Ratio: 1.05 [95% CI: 1.04-1.06]), being a woman (1.33 [1.06-1.60]) and reporting depressive symptoms (1.90 [1.65-2.18]). Among those with ADL impairment, 67.8% had at least one unmet need. Severe ADL impairment was found in 202 (6.7%) respondents, who reported lower prevalence of unmet need (43.1%). Severe ADL impairment was associated with depressive symptoms (2.55 [2.11-3.07]) to a stronger degree than any ADL impairment. Discussion Prevalence of ADL impairment and unmet need was high in this setting. Variation in impairment across the population highlighted key groups for future interventions. Unmet need for care was highest in middle-aged adults, indicating a gap in care provision.


Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Julius Griauzde ◽  
Lynda D Lisabeth ◽  
Chengwei Li ◽  
Brisa N Sanchez ◽  
Erin Case ◽  
...  

Background: We evaluated 3-month neurologic, functional, cognitive, and quality of life (QOL) outcomes in intracerebral hemorrhage (ICH) overall, and by sex and ethnicity in a population-based community study. Methods: Spontaneous ICH patients were identified from the Brain Attack Surveillance in Corpus Christi (BASIC) project from November 2008 to December 2013. Demographics and Glasgow Coma Scale were abstracted from medical records. Outcomes assessed included neurologic (National Institute of Health Stroke Scale (NIHSS): range, 0-42), functional (activities of daily living/instrumental activities of daily living: range 1-4, higher worse), cognitive (Modified Mini-Mental State Examination (mMMSE): range, 0-100), and QOL (Short-form Stroke Specific QOL scale: range, 0-5, higher better). Ethnic and sex differences were assessed with Tobit regression adjusted for age, sex or ethnicity, and presenting Glasgow Coma Scale. Results: A total of 245 patients completed baseline interviews, with 103 (42%) dying prior to follow-up, leaving 142 eligible for outcome assessment. 3-month follow up was completed on 100 (neurologic), 107 (functional), 79 (cognitive), and 83 (QOL) participants. Median age was 66 (interquartile range (IQR), 58.0-77.0). The overall median 3-month NIHSS was 2.0 (IQR, 1.0-6.0), with other baseline characteristics and outcomes shown in Table 1. Cognitive outcomes were worse in Mexican Americans (MA) compared to non-Hispanic Whites (NHW) after multivariable adjustment (MA scoring 13.3 mMMSE points lower than NHW (95% CI: 5.8, 20.7; p=.0005)). There was no difference by sex or ethnicity in neurological, functional, or QOL outcomes either before or after adjustment. Conclusions: In this population-based study, ICH survivors have remarkably favorable neurologic, functional, cognitive and QOL outcomes. There is an important disparity for worse cognitive outcome in MAs compared with NHWs.


BMJ Open ◽  
2017 ◽  
Vol 7 (8) ◽  
pp. e016996 ◽  
Author(s):  
Yajun Liang ◽  
Anna-Karin Welmer ◽  
Jette Möller ◽  
Chengxuan Qiu

BackgroundData on trends for disability in instrumental activity of daily living (IADL) are sparse in older Chinese adults.ObjectivesTo assess trends in prevalence and incidence of IADL disability among older Chinese adults and to explore contributing factors.DesignPopulation based study.Setting15 provinces and municipalities in China.SubjectsParticipants (age ≥60) were from four waves of the China Health and Nutrition Survey, conducted in 1997 (n=1533), 2000 (n=1581), 2004 (n=2028) and 2006 (n=2256), and from two cohorts constructed within the national survey: cohort 1997–2004 (n=712) and cohort 2000–2006 (n=823).MeasurementsIADL disability was defined as inability to perform one or more of the following: shopping, cooking, using transportation, financing and telephoning. Data were analysed with logistic regression and generalised estimating equation models.ResultsThe prevalence of IADL disability significantly decreased from 1997 to 2006 in the total sample and in all of the subgroups by age, sex, living region and IADL items (all ptrend<0.05). The incidence of IADL disability remained stable from cohort 1997-2004 to cohort 2000-2006 in the total sample and in all of the subgroups (all p>0.10). The recovery rate from IADL disability significantly increased over time in those aged 60–69 years (p=0.03). Living in a rural area or access to local clinics for healthcare was less disabling over time (ptrend<0.02).ConclusionsThe prevalence of IADL disability decreased among older Chinese adults during 1997–2006, whereas the incidence remained stable. The declining prevalence of IADL disability might be partly due to the decreased duration of IADL disability, and to improvements in living conditions and healthcare facilities over time.


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