Effect of Antihypertensive Treatment on Cardiovascular Events in Elderly Hypertensive Patients: Japan's Benidipine Research on Anti-Hypertensive Effects in the Elderly (J-BRAVE)

2011 ◽  
Vol 33 (2) ◽  
pp. 133-140 ◽  
Author(s):  
Ikuo Saito ◽  
Hiromichi Suzuki ◽  
Shigeru Kageyama ◽  
Takao Saruta
Keyword(s):  
Cardiovascular Events ◽  
Antihypertensive Treatment ◽  
The Elderly ◽  
Hypertensive Patients ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients

scholarly journals Left ventricular hypertrophy is a predictor of cardiovascular events in elderly hypertensive patients

2016 ◽  
Vol 34 (11) ◽  
pp. 2280-2286 ◽  
Author(s):  
Riitta L. Antikainen ◽  
Ruth Peters ◽  
Nigel S. Beckett ◽  
Robert H. Fagard ◽  
Ji-Guang Wang ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Cardiovascular Events ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients

Abstract P190: Antihypertensive Treatment Improves Left Ventricular Geometry After 10 Years Even In Elderly Hypertensive Patients

Hypertension ◽  
2021 ◽  
Vol 78 (Suppl_1) ◽  
Author(s):  
Ayumi Toba ◽  
Joji Ishikawa ◽  
Kazumasa Harada
Keyword(s):  
Blood Pressure ◽  
Antihypertensive Treatment ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Night Time ◽  
Hypertensive Patients ◽  
Ventricular Geometry ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients ◽  
The Impact

Introduction: Both ageing and high blood pressure (BP) is associated with a risk of left ventricular hypertrophy; therefore, it is unclear whether antihypertensive treatment for 10 years period reduce cardiac hypertrophy and concentricity beyond the impact of ageing. We assessed the hypothesis that even in elderly patients, BP reduction is effective for left ventricular remodeling. Methods: Among 558 hypertensive patients without concurrent heart disease referred to a cardiology clinic who underwent echocardiography and ambulatory blood pressure monitoring, 151 patients’ data of echocardiography was available after 10 years of follow up period. We evaluated the relation among BP at baseline, antihypertensive medications, and change in echocardiographic parameters of left ventricular geometry. Results: Mean age was 70.8±8.2 years at baseline. 24-hour BP was 127.4±16.4/71.4±9.6mmHg, awake BP was 129.9±17.1/72.4±10.2mmHg, and asleep BP was 122.5±16.9/67.1±9.1 mmHg. After 10 years (mean age 81.0±9.0 years), number of antihypertensive increased from 1.3±1.2 to 2.0±1.1. Left ventricular mass index (LVMI) insignificantly decreased from 115.7 to 98.7mg/m 2 (p=0.167)and relative wall thickness (RWT) significantly decreased from 0.51 to 0.47(p<0.001). There were 12% of patients with normal left ventricular geometry (N), 52% with concentric remodeling (CR), 9% with eccentric hypertrophy (EH), and 27% with concentric hypertrophy (CH) at baseline. Among patients with N or CR at baseline, those who developed to CH or EH had higher night time systolic BP (126.5±17.0 vs 118.9 ±15.4, p=0.037) than those who did not. Neither number nor type of antihypertensive was related to this geometry change. In logistic regression analysis, night time systolic BP was significantly related to the progression of hypertrophy adjusting for age, sex, BMI, LVMI, RWT, and clinic systolic BP at baseline (p=0.04). Conclusions: Even in elderly hypertensive patients, antihypertensive treatment for 10 years improved LV geometry in spite of ageing. Nighttime BP at baseline predicted worsening of LV geometry after 10 years beyond clinic BP.

scholarly journals Correlation between Knowledge and the Adherence to Take Antihypertensive Medication for Elderly Hypertensive Patients in Krian Public Health Center Sidoarjo Regency

2019 ◽  
Vol 15 (2) ◽  
pp. 103
Author(s):  
Sukma Sahadewa ◽  
Kadek Dwipa ◽  
Gede Abi Yoga ◽  
Mandasari Dwi Pertiwi
Keyword(s):  
Public Health ◽  
Health Center ◽  
Antihypertensive Medication ◽  
The Elderly ◽  
Hypertensive Patients ◽  
Public Health Center ◽  
Arterial Blood ◽  
Long Term Treatment ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients

Abstract: Hypertension is a condition of elevated abnormal arterial blood pressure that lasts persistently. Some knowledge that should be known by hypertensive patients are such as the meaning of hypertension, the cause of hypertension, the symptoms that come along, and the importance of regular and long term treatment, also knowing the dangers posed if not taking the medication. This study aims to determine the correlation between knowledge and adherence to taking antihypertensive medication in elderly hypertensive patients at the Krian Public Health Center, Sidoarjo Regency. In this study, the population was elderly hypertensive patients who examined themselves or only took control to take medication at the Elderly Polyclinic of Krian Public Health Center in Sidoarjo Regency with 332 populations with 75 samples taken. The result of this research was obtained sig. value = 0,000 (<0,05). This study used the Spearman Correlation statistical test in analyzing the data. From the results of this study it was concluded that there was a relationship between knowledge and adherence to taking antihypertensive medication in elderly hypertensive patients at the Krian Public Health Center, Krian District, this was proved by the acquisition of sig values. = 0,000 (<0.05). Keywords: knowledge, the adherence of taking medication, hypertension

scholarly journals STATE OF THE PLATELET HEMOSTASIS IN THE MIDDLE-AGED AND THE ELDERLY HYPERTENSIVE PATIENTS

2020 ◽  
Vol 2 (12) ◽  
pp. 120-125
Author(s):  
V. S. Pasko
Keyword(s):  
Essential Hypertension ◽  
Elderly Patients ◽  
The Elderly ◽  
Control Group ◽  
Middle Aged ◽  
Hypertensive Patients ◽  
Group I ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients ◽  
Induced Aggregation

It has long been known that complications of essential hypertension are associated mostly with disorders of blood coagulation system and degree of absolute risk of cardiovascular events is growing with increasing of age. That is why much attention is paid to more detailed study of mechanisms of thrombosis as the component of complications of essential hypertension through lens of hemostatic changes at present. Therefore, regulatory mechanisms of initiation of thrombus formation and participation of platelet hemostasis are studied in hypertensive patients insufficiently today. The aim of the study was to identify the baseline levels of the platelet hemostasis indices in the middle-aged and the elderly hypertensive patients. Material and methods. We performed the comparative assessment of status of the platelet hemostasis in 63 middle-aged (group I) and 53 elderly patients (group II) respectively to clarify this issue in our work. Patients of the surveyed groups were comparable in age, sex and related pathology. The control group consisted of 15 patients for every of the surveyed groups (group III the middle-aged and group IV the elderly respectively) matched with basic by age and gender. Conclusions. Therefore, there is the increase in platelet activity depending on age in the middle-aged and the elderly hypertensive patients that is manifested by adrenaline stimulation most clearly. In addition, the most significant changes are determined in the spontaneous and the adrenaline-induced aggregation namely in amplitude and slope of aggregation in the spontaneous and time of maximal aggregation in the adrenaline-induced aggregation in the patients of older age group compared with the middle-aged patients. The substantial deceleration of time of maximal aggregation during the adrenaline stimulated aggregation in 1,6 times (p<0,001) in the elderly patients confirms the expressed thrombogenicity and sensitiveness to neurohumoral influences too. Thus, the blood plasma thrombogenicity revealed in the study of the platelet hemostasis in the elderly indicates a high probability of thrombotic complications developing in this category of the patients and this is consistent with literature.

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