Early detection of fetal abnormalities by three-dimensional sonography

2002 ◽  
Vol 2 (1) ◽  
pp. 43-49
Author(s):  
T. Hafner ◽  
A. Kurjak ◽  
M. Kos ◽  
I. Bekavac ◽  
B. Funduk-Kurjak
Author(s):  
Ritsuko K Pooh

ABSTRACT After introduction of high-frequency vaginal transducer, transvaginal two-dimensional ultrasound has established a field of sonoembryology and most of the major fetal abnormalities have been detectable in the first trimester. Three-dimensional ultrasound adds an objective and comprehensive information to two-dimensional sonographic findings. How to cite this article Pooh RK. Early Detection of Fetal Abnormality. Donald School J Ultrasound Obstet Gynecol 2013;7(1):46-50.


2002 ◽  
Vol 2 (1) ◽  
pp. 43-49
Author(s):  
T. Hafner ◽  
A. Kurjak ◽  
M. Kos ◽  
I. Bekavac ◽  
B. Funduk-Kurjak

2009 ◽  
Vol 14 (6) ◽  
pp. 060503 ◽  
Author(s):  
Jiechen Yin ◽  
Gangjun Liu ◽  
Jun Zhang ◽  
Lingfeng Yu ◽  
Sari Mahon ◽  
...  

Blood ◽  
2015 ◽  
Vol 126 (23) ◽  
pp. 2158-2158
Author(s):  
Hala Mounir Mohamed Moustafa Agha ◽  
Antoine AbdelMassih ◽  
Mohamed Youssef Abd El Rahman ◽  
Ornella Milanesi, ◽  
Biagio Castaldi ◽  
...  

Abstract Background: Among patients with beta-thalassemia early detection of transfusion-induced myocardial iron loading and its intervention with aggressive chelation therapy may delay or reverse heart failure. Three dimensional speckle tracking echocardiography (3D-STE) is a novel tool that may early detect myocardial affection in these patients. Methods: Thirty-two thalassemic patients with a mean age of 18.1± 7.03 years and 30 aged matched healthy control subjects have been included in the study. Patients have been recruited from pediatric hematology clinics in both Cairo University, Egypt (n=18) and Padova University, Italy (n=14). 3D-STE was performed to all patients and control subjects in addition to the myocardial relaxometry T2* by cardiac MRI. Results: The left ventricular ejection fraction (LVEF) derived from 3D echocardiography among the studied thalassemia patients was within normal range 62.5± 5.6%. Compared to the normal subjects, thalassemia patients had a statistical significant reduction of the left ventricular global longitudinal strain (-16.81± 0.93% vs -18.76 ± 1.12 %, p=0.001), the left ventricular global circumferential strain (-10.56 ± 0.61% vs -11.83 ± 0.71 %, p=0.001 ) and the left ventricular global area strain (-20.13 ±1.18% vs -22.48 ±,1.29 %, p=0.001). No statistical significant correlation was found between the severity of myocardial iron overload measured by T2* and the measured left ventricular global strain. Conclusion: In asymptomatic thalassemia patients with preserved left ventricular global systolic function 3D-STE derived strain can detect early subtle myocardial dysfunction. The observed subtle myocardial deformation dysfunction is not related to the extent of myocardial iron deposition. Disclosures No relevant conflicts of interest to declare.


2012 ◽  
Vol 15 (1) ◽  
pp. 43-49 ◽  
Author(s):  
José A. Carmona Torres ◽  
Adolfo J. Cangas ◽  
Gustavo R. García ◽  
Álvaro I. Langer ◽  
Roberto Zárate

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Secil Aksoy ◽  
Kaan Orhan

Aim. Osteonecrosis can affect the mandibular condyle, and bone marrow edema may be a precursor in osteonecrosis development in temporomandibular disorder (TMD) patients. Early detection of bone marrow changes is crucial for occurring osteonecrosis. The purpose of this study was to compare the diagnostic value of fast spin-echo T2 weighted (FSE-T2W), fat-suppressed T2W (FS-T2W), and three-dimensional (3D) fast imaging employing steady-state acquisition (FIESTA-C) MR sequences for early detection of bone marrow changes as well as TMJ soft tissue alterations. Methods. A total of 60 joints with TMD were included in this study using a 1.5T MR machine (Signa HDxt, GE, Milwaukee, USA) using a dual surface TMJ coil. Qualitatively, the images were interpreted by two observers for disk configuration, disk position, joint fluid, and bone marrow changes. Quantitatively, signal intensity ratios (SIR) in the TMJ condyle, retrodiscal tissue, disk, and muscle were also measured using all tested sequences. Kappa coefficients were calculated to assess both intra- and interobserver agreements for each image set. The SIR of each sequence was compared using a one-way ANOVA Bonferroni-Dunn test. Results. Overall intraobserver kappa coefficients ranged between 0.35 and 0.88 for joint fluid and between 0.22 and 0.82 for bone marrow changes diagnosis, suggesting high intraobserver agreement for FS-T2W and 3D FIESTA-C sequences than FSE T2W sequence ( p < 0.05 ). 3D FIESTA-C showed higher agreement values for disk configuration and position detection than other sequences. Conclusions. 3D FIESTA-C sequences can be used and incorporated into routine MRI protocols for obtaining high-resolution TMJ MR images due to the short acquisition time and 3D nature of the sequence. Additional studies should be done for dynamic TMJ imaging with this sequence.


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