scholarly journals Core outcomes in children and adolescents with overweight/obesity exposed to physical activity interventions: protocol for the development of a core outcome set

2020 ◽  
Author(s):  
Cíntia Ehlers Botton ◽  
Angélica Trevisan De Nardi ◽  
Lucinéia Orsolin Pfeifer ◽  
Lucas Porto Santos ◽  
Larissa Xavier Neves da Silva ◽  
...  
Keyword(s):  
Physical Activity ◽  
Clinical Trials ◽  
Children And Adolescents ◽  
Core Outcome Set ◽  
Core Outcome ◽  
Obese Children ◽  
Physical Activity Interventions ◽  
Outcome Set ◽  
Core Outcomes

This is the protocol for development of a COS related to clinical trials with physical activity interventions for overweight or obese children and adolescents, as well as categorize them into specific domains.

scholarly journals Impact of school-based physical activity interventions in primary schools: measuring what matters

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
B Ram ◽  
T Venkatraman ◽  
K Foley ◽  
K Honeyford ◽  
L Ells ◽  
...  
Keyword(s):  
Physical Activity ◽  
Emotional Health ◽  
Evidence Synthesis ◽  
Core Outcome Set ◽  
Core Outcome ◽  
Future Studies ◽  
Physical Activity Interventions ◽  
School Based ◽  
Key Stakeholders ◽  
Outcome Set

Abstract Background A growing number of small studies suggest that school-based physical activity initiatives can help children achieve the recommended 60 minutes of physical activity per day. However, the heterogeneity of outcomes and measures used in small studies prevents pooling of results to demonstrate whether short-term health benefits are sustained. Qualitative studies suggest many benefits that are not represented by outcomes in trials to date. The aim of this study was to generate a list of outcomes that have been studied to develop a core outcome set (COS) acceptable to key stakeholders for future studies evaluating school-based physical activity initiatives. Methods We searched six databases (MEDLINE, EMBASE, PsycINFO, CINAHL, CENTRAL and Cochrane Database of Systematic Reviews) systematically for reviews of school-based physical activity interventions, and extracted relevant studies to identify the outcomes and measures used in each paper. A long list was generated from the literature and a previous workshop with stakeholders. This study is registered with COMET (#1322), and with PROSPERO (CRD42019146621). Results 75/121 cited studies drawn from 53/2409 reviews met our inclusion criteria. We grouped 65 outcomes into 3 domains: (i) physical activity and health (ii) social and emotional health, and (iii) educational attainment. We will conduct two Delphi survey rounds with four stakeholder groups (health professionals, researchers, educators and parents) to rate the importance of each outcome. A core outcome set will be generated from a consensus process. Conclusions There is currently a large variation of outcomes and measures studied that precludes evidence synthesis of the impact of school-based physical activity interventions. Consensus methods are needed to focus research on the outcomes that matter the most to key stakeholders and to provide tools for future studies to assess long-term impact. Key messages Variations in outcomes studied precludes evidence synthesis of SBPA intervention impacts. A core outcome set is needed to ensure future SBPA interventions measure outcomes that matter the most.

scholarly journals 566 Acne core outcomes research network: Progress in core outcome set development in clinical trials

2018 ◽  
Vol 138 (5) ◽  
pp. S96 ◽  
Author(s):  
D. Thiboutot ◽  
A. Layton ◽  
M. Chren ◽  
M. Patel ◽  
E. Otchere ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Outcomes Research ◽  
Core Outcome Set ◽  
Research Network ◽  
Core Outcome ◽  
Outcome Set ◽  
Core Outcomes

scholarly journals Protocol for developing a core outcome set for evaluating school-based physical activity interventions in primary schools

BMJ Open ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. e031868
Author(s):  
Kimberley A Foley ◽  
Tishya Venkatraman ◽  
Bina Ram ◽  
Louisa Ells ◽  
Esther van Sluijs ◽  
...  
Keyword(s):  
Public Health ◽  
Physical Activity ◽  
Primary School ◽  
Primary Schools ◽  
Core Outcome Set ◽  
Primary School Children ◽  
Core Outcome ◽  
Physical Activity Interventions ◽  
School Based ◽  
Outcome Set

IntroductionPrimary school-based physical activity interventions, such as The Daily Mile initiative, have the potential to increase children’s physical activity levels over time, which is associated with a variety of health benefits. Comparing interventions or combining results of several studies of a single intervention is challenging because previous studies have examined different outcomes or used different measures that are not feasible or relevant for researchers in school settings. The development and implementation of a core outcome set (COS) for primary school-based physical activity interventions would ensure outcomes important to those involved in implementing and evaluating interventions are standardised.Methods and analysisOur aim is to develop a COS for studies of school-based physical activity interventions. We will achieve this by undertaking a four-stage process:(1) identify a list of outcomes assessed in studies through a systematic review of international literature; (2) establish domains from these outcomes to produce questionnaire items; (3) prioritise outcomes through a two-stage Delphi survey with four key stakeholder groups (researchers, public health professionals, educators and parents), where stakeholders rate the importance of each outcome on a 9-point Likert scale (consensus that the outcomes should be included in the COS will be determined as 70% or more of all stakeholders scoring the outcome 7%–9% and 15% or less scoring 1 to 3); (4) achieve consensus on a final COS in face-to-face meetings with a sample of stakeholders and primary school children.Ethics and disseminationWe have received ethical approval from Imperial College London (ref: 19IC5428). The results of this study will be disseminated via conference presentations/public health meetings, peer-reviewed publications and through appropriate media channels.Trial registration numberCore Outcome Measures in Effectiveness Trials Initiative (COMET) number: 1322.

scholarly journals Proposing a Core Outcome Set for Physical Activity and Exercise Interventions in People With Rare Neurological Conditions

2021 ◽  
Vol 2 ◽  
Author(s):  
Gita Ramdharry ◽  
Valentina Buscemi ◽  
Annette Boaz ◽  
Helen Dawes ◽  
Thomas Jaki ◽  
...  
Keyword(s):  
Physical Activity ◽  
Outcome Measurement ◽  
Core Outcome Set ◽  
Well Being ◽  
Core Outcome ◽  
Exercise Interventions ◽  
Physical Activity Interventions ◽  
Outcome Set ◽  
Neurological Conditions ◽  
Meta Analyses

Rare neurological conditions (RNCs) encompass a variety of diseases that differ in progression and symptoms but typically include muscle weakness, sensory and balance impairment and difficulty with coordinating voluntary movement. This can limit overall physical activity, so interventions to address this are recommended. The aim of this study was to agree a core outcome measurement set for physical activity interventions in people living with RNCs. We followed established guidelines to develop core outcome sets. Broad ranging discussions in a series of stakeholder workshops led to the consensus that (1) physical well-being; (2) psychological well-being and (3) participation in day-to-day activities should be evaluated in interventions. Recommendations were further informed by a scoping review of physical activity interventions for people living with RNCs. Nearly 200 outcome measures were identified from the review with a specific focus on activities or functions (e.g, on lower limb function, ability to perform daily tasks) but limited consideration of participation based outcomes (e.g., social interaction, work and leisure). Follow on searches identified two instruments that matched the priority areas: the Oxford Participation and Activities Questionnaire and the Sources of Self-Efficacy for Physical Activity. We propose these scales as measures to assess outcomes that are particularly relevant to assess when evaluating physical activity interventions mong people with RNCs. Validation work across rare neurological conditions is now required to inform application of this core outcome set in future clinical trials to facilitate syntheses of results and meta-analyses.

Postinflammatory hyperpigmentation: protocol for development of a core outcome set for clinical trials

2021 ◽  
Author(s):  
Bianca Y. Kang ◽  
Sarah A. Ibrahim ◽  
Divya Shokeen ◽  
Daniel I. Schlessinger ◽  
Jamie J. Kirkham ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Core Outcome Set ◽  
Core Outcome ◽  
Outcome Set ◽  
Postinflammatory Hyperpigmentation

A multi-stakeholder Delphi consensus core outcome set for clinical trials in moderate-to-severe asthma (coreASTHMA)

2021 ◽  
Author(s):  
Vickram Tejwani ◽  
Hsing-Yuan Chang ◽  
Annie P. Tran ◽  
Jennifer Al Naber ◽  
Florian S. Gutzwiller ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Severe Asthma ◽  
Core Outcome Set ◽  
Core Outcome ◽  
Delphi Consensus ◽  
Outcome Set ◽  
Multi Stakeholder

Identifying Outcomes in Clinical Trials of Fistulizing Crohn’s Disease for the Development of a Core Outcome Set

2019 ◽  
Vol 17 (9) ◽  
pp. 1904-1908 ◽  
Author(s):  
Christopher Ma ◽  
Claire E. Parker ◽  
Tran M. Nguyen ◽  
Reena Khanna ◽  
Brian G. Feagan ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Core Outcome Set ◽  
Core Outcome ◽  
Outcome Set

scholarly journals A protocol for developing a core outcome set for ectopic pregnancy

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Krystle Y. Chong ◽  
Sarah Solangon ◽  
James Kemper ◽  
Kurt Barnhart ◽  
Pamela Causa Andrieu ◽  
...  
Keyword(s):  
Ectopic Pregnancy ◽  
Randomised Controlled Trials ◽  
Core Outcome Set ◽  
Future Research ◽  
Controlled Trials ◽  
Core Outcome ◽  
Key Stakeholders ◽  
Outcome Set ◽  
Core Outcomes ◽  
Randomised Controlled

Abstract Background Randomised controlled trials (RCTs) evaluating ectopic pregnancy have reported many different outcomes, which are themselves often defined and measured in distinct ways. This level of variation results in an inability to compare results of individual RCTs. The development of a core outcome set to ensure outcomes important to key stakeholders are collected consistently will guide future research in ectopic pregnancy. Study aim To develop and implement a core outcome set to guide future research in ectopic pregnancy. Methods and analysis We have established an international steering group of key stakeholders, including healthcare professionals, researchers, and individuals with lived experience of ectopic pregnancy. We will identify potential outcomes from ectopic pregnancy from a comprehensive literature review of published randomised controlled trials. We will then utilise a modified Delphi method to prioritise outcomes. Subsequently, key stakeholders will be invited to score potential core outcomes on a nine-point Likert scale, ranging from 1 (not important) to 9 (critical). Repeated reflection and rescoring should promote whole and individual stakeholder group convergence towards consensus ‘core’ outcomes. We will also establish standardised definitions and recommend high-quality measurements for individual core outcomes. Trial registration COMET 1492. Registered in November 2019.

Sign in / Sign up

Export Citation Format

Share Document