scholarly journals Some Revenge Now or More Revenge Later? Applying an Intertemporal Framework to Retaliatory Aggression

2021 ◽  
Author(s):  
Samuel James West ◽  
Emily Lasko ◽  
Calvin Hall ◽  
Nayaab Khan ◽  
David Chester
Keyword(s):  
Aggressive Behavior ◽  
Antisocial Behavior ◽  
Delay Discounting ◽  
Total N ◽  
Angry Rumination ◽  
Rewarding Behavior ◽  
Experimentally Induced

Retaliatory aggression is a rewarding behavior. Decisions about rewarding behaviors often involve an intertemporal bias, such that people prefer immediate rewards and discount delayed rewards. We integrated these literatures to test whether the delay discounting framework could be applied to retaliatory aggression. Across six studies (total N = 1,508), participants repeatedly chose between immediate-but-lesser or delayed-but-greater retaliation. As with other rewards (e.g., money), participants preferred immediate-but-lesser retaliation, discounting the value of delayed-but-greater revenge. Rates of aggression discounting were temporally stable andassociated with greater aggressive behavior. Experimentally-induced angry rumination reduced discounting rates, motivating participants to wait longer to inflict greater harm. Participants with greater antagonistic traits (e.g., physical sadism), displayed stronger preferences for delayed-but greater vengeance. These findings suggest that some dispositionally aggressive individuals may delay retaliation in service of greater future revenge. Our results bolster the important role of reward in retaliatory aggression and suggest that an intertemporal framework is likely a fruitfularea of investigation for antisocial behavior. We discuss the implications of our findings in relation to contemporary theories of aggression and broader theories of antisocial behavior.

scholarly journals Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure

2018 ◽  
Vol 45 (8) ◽  
pp. 1252-1268 ◽  
Author(s):  
David S. Chester ◽  
C. Nathan DeWall ◽  
Brian Enjaian
Keyword(s):  
Negative Affect ◽  
Positive Affect ◽  
Aggressive Behavior ◽  
Crucial Role ◽  
Total N ◽  
Potent Predictor

Sadism is a “dark” trait that involves the experience of pleasure from others’ pain, yet much is unknown about its link to aggression. Across eight studies (total N = 2,255), sadism predicted greater aggression against both innocent targets and provocateurs. These associations occurred above-and-beyond general aggressiveness, impulsivity, and other “dark” traits. Sadism was associated with greater positive affect during aggression, which accounted for much of the variance in the sadism–aggression link. This aggressive pleasure was contingent on sadists’ perceptions that their target suffered due to their aggressive act. After aggression, sadism was associated with increases in negative affect. Sadism thus appears to be a potent predictor of aggression that is motivated by the pleasure of causing pain. Such sadistic aggression ultimately backfires, resulting in greater negative affect. More generally, our results support the crucial role of anticipated and positive forms of affect in motivating aggression.

scholarly journals Sadism and Aggressive Behavior: Inflicting Pain to Feel Pleasure

2018 ◽  
Author(s):  
David Skylan Chester ◽  
C. Nathan DeWall ◽  
Brian Enjaiain
Keyword(s):  
Negative Affect ◽  
Positive Affect ◽  
Aggressive Behavior ◽  
Crucial Role ◽  
Total N ◽  
Potent Predictor

Sadism is a ‘dark’ trait that involves the experience of pleasure from others’ pain, yet much is unknown about its link to aggression. Across eight studies (total N=2,255), sadism predicted greater aggression against both innocent targets and provocateurs. These associations occurred above-and-beyond general aggressiveness, impulsivity, and other ‘dark’ traits. Sadism was associated with greater positive affect during aggression, which accounted for much of the variance in the sadism-aggression link. This aggressive pleasure was contingent on sadists’ perceptions that their target suffered due to their aggressive act. After aggression, sadism was associated with increases in negative affect. Sadism thus appears to be a potent predictor of aggression that is motivated by the pleasure of causing pain. Such sadistic aggression ultimately backfires, resulting in greater negative affect. More generally, our results support the crucial role of anticipated and positive forms of affect in motivating aggression.

Experimental Amyloidosis Induced by Immune Complex

1971 ◽  
Vol 29 ◽  
pp. 582-583
Author(s):  
A. Kawaoi
Keyword(s):  
Immune Complex ◽  
Systemic Amyloidosis ◽  
Human Diseases ◽  
Experimental Amyloidosis ◽  
Freund’S Complete Adjuvant ◽  
Freund's Complete Adjuvant ◽  
Immunological Approach ◽  
Experimentally Induced

Numbers of immunological approach have been made to the amyloidosis through the variety of predisposing human diseases and the experimentally induced animals by the greater number of agents. The results suggest an important role of impaired immunity involving both humoral and cell-mediated aspects.Recently the author has succeeded in producing amyloidosis in the rabbits and mice by the injections of immune complex of heat denatured DNA.The aim of this report is to demonstrate the details of the ultrastructure of the amyloidosis induced by heterologous insoluble immune complex. Eleven of twelve mice, dd strain, subcutaneously injected twice a week with Freund's complete adjuvant and four of seven animals intraperitonially injected developed systemic amyloidosis two months later from the initial injections. The spleens were electron microscopically observed.

Supernatural norm enforcement: Thinking about Karma and God reduces selfishness among believers

2018 ◽  
Author(s):  
Cindel White ◽  
John Michael Kelly ◽  
Azim Shariff ◽  
Ara Norenzayan
Keyword(s):  
Social Norms ◽  
Framing Effects ◽  
Demographic Variables ◽  
Exclusion Criteria ◽  
Total N ◽  
Norm Enforcement ◽  
Dictator Games ◽  
Within Subjects

Four experiments (total N = 3591) examined how thinking about Karma and God increases adherence to social norms that prescribe fairness in anonymous dictator games. We found that (1) thinking about Karma decreased selfishness among karmic believers across religious affiliations, including Hindus, Buddhists, Christians, and non-religious Americans; (2) thinking about God also decreased selfishness among believers in God (but not among non-believers), replicating previous findings; and (3) thinking about both karma and God shifted participants’ initially selfish offers towards fairness (the normatively prosocial response), but had no effect on already fair offers. These supernatural framing effects were obtained and replicated in high-powered, pre-registered experiments and remained robust to several methodological checks, including hypothesis guessing, game familiarity, demographic variables, between- and within-subjects designs, and variation in data exclusion criteria. These results support the role of culturally-elaborated beliefs about supernatural justice as a motivator of believer’s adherence to prosocial norms.

STEROID RECEPTOR PHENOTYPE, EXPRESSION OF HER-2/NEU, PD-1, PD-L1 AND LYMPHOCYTIC-MACROPHAGAL INFILTRATION OF ENDOMETRIAL CARCINOMAS: COMPARISON OF MODERN MOLECULAR BIOLOGICAL TYPES OF THE DISEASE (THE ROLE OF BODY MASS INDEX)

2020 ◽  
Vol 66 (1) ◽  
pp. 71-78
Author(s):  
Lev Bershteyn ◽  
Aleksandr Ivantsov ◽  
Aglaya Ievleva ◽  
A. Venina ◽  
I. Berlev
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Tumor Tissue ◽  
Immunohistochemical Analysis ◽  
The Body ◽  
Molecular Profile ◽  
Total N ◽  
Number Of Patients ◽  
Her 2

The aim of this study was to evaluate steroid receptors’ status of tumor tissue in different molecular biological types of endometrial cancer (EC), subdivided according to the current classification, and their colonization by lymphocytic and macrophage cells, taking into account body mass index of the patients. Materials and methods: Material from treatment-naive patients with EC (total n = 229) was included; the number of sick persons varied depending on the method used. The average age of patients was close to 60 years, and about 90% of them were postmenopausal. It was possible to divide the results of the work into two main subgroups: a) depending on the molecular biological type of the tumor (determined on the basis of genetic and immunohistochemical analysis), and b) depending on the value of the body mass index (BMI). The latter approach was used in patients with EC type demonstrating a defective mismatch repair of the incorrectly paired nucleotides (MMR-D) and with a type without characteristic molecular profile signs (WCMP), but was not applied (due to the smaller number of patients) in EC types with a POLE gene mutation or with expression of the oncoprotein p53. According to the data obtained, when comparing various types of EC, the lowest values of Allred ER and PR scores were revealed for POLE-mutant and p53 types, while the “triple-negative” variant of the tumor (ER-, PR-, HER2/neu-) was most common in POLE-mutant (45.5% of cases) and WCMP (19.4%) types of EC. The p53+ type of EC is characterized by inclination to the higher expression of the macrophage marker CD68 and lymphocytic Foxp3, as well as mRNA of PD-1 and SALL4. In addition to the said above, for WCMP type of EC is peculiar, on the contrary, a decrease in the expression of lymphocytic markers CD8 (protein) and PD-L1 (mRNA). When assessing the role of BMI, its value of >30.0 (characteristic for obesity) was combined with an inclination to the increase of HER-2/neu expression in the case of MMR-D EC type and to the decrease of HER-2 /neu, FOXp3 and ER expression in WCMP type. Conclusions: The accumulated information (mainly describing here hormonal sensitivity of the tumor tissue and its lymphocytic-macrophage infiltration) additionally confirms our earlier expressed opinion that the differences between women with EC are determined by both the affiliation of the neoplasm to one or another molecular biological type (subdivided according to the contemporary classification), as well as by body mass value and (very likely) the associated hormonal and metabolic attributes.

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