COMPLICACIONES EN NEONATOS DE MADRES DIAGNOSTICADAS DE ZIKA EN EL DISTRITO 09D01 ZONAL 8 DE SALUD DE LA CIUDAD DE GUAYAQUIL

Introducción: la infección por el virus del Zika es un problema de salud pública por las complicaciones neonatales de moderada y grave severidad. Objetivo: establecer las complicaciones en los neonatos de madres diagnosticadas con Zika. Metodología: investigación cuantitativa, no experimental, descriptiva, con una muestra de 82 neonatos de madres con infección de virus del Zika, datos obtenidos del departamento de estadísticas del Distrito 09D01, durante el periodo enero 2017 a enero 2018, procesados por el software SPSS Estatistics 24.0 para windows, con una distribución numérica y porcentual, con la prueba de T de Student se estableció la significancia estadística (p<0.05). Resultados: En los 82 neonatos de madres infectadas con el virus Zika 52 casos (63,4 %) nacieron por cesárea y 30 casos (36,59 %) por parto vaginal, 76 casos (92,68%) nacieron vivos y 6 casos (7,3%) mortinatos, con igual proporción de neonatos pre-términos y a términos, microcefalia en 13 casos (15,88%), seguido de hiperbilirrubinemia en 5 casos (6,10%) e hipotiroidismo en 3 casos (3,66%), con una diferencia significativa (p<0,05) en la microcefalia en relación a las otras complicaciones. Conclusiones: Se evidenció un predominio en el tipo de parto por cesáreas, aunque diversos consensos internacionales establecen que la infección por el virus Zika o la microcefalia no son indicaciones, por lo que la cesárea se realizará solo por motivos obstétricos exclusivamente. En los neonatos existió igual proporción en la edad gestacional y se evidenciaron complicaciones como microcefalia, hiperbilirrubinemia e hipotiroidismo predominando la microcefalia en relación a las otras complicaciones. Palabras Clave: Zika; neonatos; gestantes, malformaciones, microcefalia, mortalidad. ABSTRACT Introduction: Zika virus infection is a public health problem due to moderate and severe neonatal complications. Objective: to establish the complications in the neonates of mothers diagnosed with Zika. Methodology: quantitative, non-experimental, descriptive research, with a sample of 82 neonates of mothers with Zika virus infection, data obtained from the statistics department of District 09D01, during the period January 2017 to January 2018, processed by the software SPSS Statistics 24.0 for windows, with a numerical and percentage distribution, with the Student's t test statistical significance was established (p<0.05). Results: In the 82 neonates of mothers infected with the Zika virus, 52 cases (63.4 %) were born by cesarean section and 30 cases (36.59%) by vaginal delivery, 76 cases (92.68%) were born alive and 6 cases (7.3%) were stillborn, with the same proportion of preterm and full term neonates, microcephaly in 13 cases (15.88%), followed by hyperbilirubinemia in 5 cases (6.10%) and hypothyroidism in 3 cases (3.66%), with a significant difference (p<0.05) in microcephaly in relation to the other complications. Conclusions: There was evidence of a predominance in the type of cesarean delivery, although various international consensuses made that infection by the Zika virus or microcephaly are not indications, so that cesarean section is performed only for obstetric reasons exclusively. In neonates there was an equal proportion in gestational age and complications such as microcephaly, hyperbilirubinemia and hypothyroidism were evidenced, with microcephaly predominating in relation to the other complications Keywords: Zika; neonates; pregnant; malformations; microcephaly; the mortality.

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Juridical perspectives of interruption of pregnancy with zika virus infection regarding medical, emotional and social consequences

Journal of Human Growth and Development ◽

10.7322/jhgd.143875 ◽

2018 ◽

Vol 28 (1) ◽

pp. 77 ◽

Cited By ~ 1

Author(s):

Ana Rita Souza Prata ◽

Daniela Pedroso ◽

Greice Menezes ◽

Jefferson Drezett ◽

José Henrique Rodrigues Torres ◽

...

Keyword(s):

Virus Infection ◽

Zika Virus ◽

Public Health Problem ◽

Criminal Code ◽

Human Infection ◽

Social Consequences ◽

Physical And Mental Health ◽

Zika Virus Infection ◽

The Republic ◽

Virus Zika

Introduction: The Zika virus was identified in 1947 in Rhesus monkeys in the Republic of Uganda and isolated in humans in 1952 in the same country. Up to 2007 there were few cases of human infection in African and Asian countries. The first outbreak of the Zika virus occurred in Brazil in 2015, becoming a serious public health problem due to the increase in the number of cases of microcephaly in infected pregnant women. Objective: To describe the legal abortion at Zika virus infection during pregnancy regarding medical, emotional and social consequences. perspectives of abortion for the pregnant woman with Zika virus regarding the medical, emotional and social consequences. Methods: This is a documentary study based on documents about abortion and its outcomes in Brazil. Technical norms, textbooks, indexed articles of Scopus and PubMed, documents extracted from international human rights treaties and conventions, and legal documents on the subject were used. It was decided to direct the text based on the experiences of each theme on abortion and its outcomes in Brazil, with a synthesis of the current scenario. Results: Recognizing the exceptional nature of this situation, it is sought to confer an interpretation according to the Constitution and Article 128 of the Criminal Code, based on an analogical application, which seeks to protect the physical and mental health of women infected by the Zika virus. It is possible to qualify the practice of abortion in these circumstances as atypical conduct by the state of necessity, excluding the unlawfulness by comparing with articles 23, I and 24 of the Penal Code. Conclusion: Authorizing the termination of pregnancy after diagnosis of the virus Zika guarantees women the free exercise of their reproductive rights, which is not confused with state imposition of abortion or eugenic practice.

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Pesquisas odontológicas relacionadas com microcefalia: um estudo bibliométrico

ARCHIVES OF HEALTH INVESTIGATION ◽

10.21270/archi.v8i11.4720 ◽

2020 ◽

Vol 8 (11) ◽

Author(s):

Virgínia Karla Pinheiro de Queiroz ◽

Diego Moura Soares

Keyword(s):

Virus Infection ◽

Zika Virus ◽

Pediatric Dentistry ◽

International Standards ◽

Growth Chart ◽

Cross Sectional ◽

Zika Virus Infection ◽

Pan American ◽

Virus Zika ◽

Health Organization

Introdução: A microcefalia é uma malformação congênita, em que o cérebro não se desenvolve de maneira adequada podendo ser efeito de uma série de fatores de diferentes origens, como substâncias químicas e agentes biológicos, como bactérias, vírus e radiação. Objetivo: realizar um levantamento bibliométrico dos estudos realizados no Brasil, por pesquisadores da área da odontologia, que tratam sobre utilizando os dados publicados nos anais da Reunião Anual da Sociedade Brasileira de Pesquisa Odontológica (SBPqO). Metodologia: Uma busca ativa foi realizada em todos os resumos publicados nos anais da SBPqO dos ultimos dez anos (2009 a 2018), utilizando o termo de busca “microcefalia” e avaliou-se aspectos como distribuição geográfica, financiamento, tipo de instituição, objetivo dos estudo e correlação da microcefalia com o Zika vírus. Resultados: Um total de 26.514 resumos foram analisados, desde apenas 10 estavam relacionados com microcefalia, sendo o ano de 2018 o que apresentou um maior número de trabalhos (5 resumos). A maioria dos resumos tratavam de trabalhos associados com a sindrome congênita do Zika vírus (7 resumos). Conclusão: A região nordeste apresentou uma maior produção relacionada a microcefalia e a grande maioria dos estudos associou a doença com a síndrome congênita do zika vírus. Uma maior sensibilização por parte dos pesquisadores a cerca da importância do conhecimento do desenvolvimento e de métodos de melhoria na qualidade de vida dessas crianças deve ser incentivado.Descritores: Microcefalia; Odontologia; Pesquisa em Odontologia.ReferênciasNunes ML, Carlini CR, Marinowic D, Kalil Neto F, Fiori HH, Scotta MC et al. Microcephaly and Zika virus: a clinical and epidemiological analysis of the current outbreak in Brazil. J Pediatr. 2016;92(3):230-40.Brasil. Ministério da Saúde do Brasil. Secretaria de Vigilância em Saúde. Monitoramento integrado de alterações no crescimento e desenvolvimento relacionadas a infecção pelo vírus zika e outras etiologias infecciosas, até a semana Epidemiologica 18/2017. Bol Epidemiol. 2017;48: 1-9.Brunoni D, Blascovi-Assis SM, Osório AAC, Seabra AG, Amato CAH, Teixeira MCTV et al . Microcefalia e outras manifestações relacionadas ao vírus Zika: impacto nas crianças, nas famílias e nas equipes de saúde. Cien saude coletiva. 2016;21(10):3297-302.De Carvalho NS, De Carvalho BF, Fugaça CA, Dóris B, Biscaia ES. Zika virus infection during pregnancy and microcephaly occurrence: a review of literature and Brazilian data. Braz J Infect Dis. 2016;20(3):282-89.Siqueira RMP, Santos MTBR, Cabral GMP. Alterations in the primary teeth of children with microcephaly in Northeast Brazil: a comparative study. Int J Paediatr Dent. 2018; 28:523-32.Cavalcanti AFC, Aguiar YPC, de Oliveira Melo AS, de Freitas Leal JIB, Cavalcanti AL, Cavalcanti SDLB. Teething symptoms in children with congenital Zika syndrome: a 2-year follow-up. Int J Paediatr Dent. 2019;29(1):74-78.Cavalcanti AL, Melo TRNB, Barroso KMA, Souza FEC, Maia AMA, Silva ALO. Perfil da Pesquisa Científica em Odontologia Realizada no Brasil. Pesq Bras Odontoped Clin Integr. 2004;4(2):99-104.Schuler-Faccini L, Ribeiro EM, Feitosa IML, Horovitz DDG, Cavalcanti DP, Pessoa A et al. Possible association between Zika virus infection and microcephaly: Brazil, 2015. Morb Mort Weekly Rep (MMWR). 2016;65(3):59-62.Butler D. Zika virus: Brazil’s surge in small-headed babies questioned by report. Nature. 2016;530(7588):13-4.Dick GW, Kitchen SF, Haddow AJ, Zika virus I. Isolations and serological specificity. Trans R Soc Trop Med Hyg. 1952;46(5):509-20.Bell TM, Field EJ, Narang HK. Zika virus infection of the central nervous system of mice. Arch Gesamte Virusforsch. 1971;35(2):183-93.Pan American Health Organization (PAHO). Lineamientos preliminares de vigilancia de microcefalia en recien nacidos em entornos con riesgo de circulacion de virus Zika. Washington, DC: Pan American Health Organization; 2016.Fenton TR, Kim JH. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC Pediatr.2013;13:59.Villar J, Cheikh Ismail L, Victora CG, Ohuma EO, Bertino E, Altman DG et al. International standards for newborn weight, length, and head circumference by gestational age and sex: the Newborn Cross-Sectional Study of the INTERGROWTH-21st Project. Lancet. 2014; 384(9946):857-68.Brasil. Secretaria Estadual de Saúde de Pernambuco. Secretaria Executiva de Vigilância em Saúde. Protocolo Clínico e Epidemiológico para investigação de casos de microcefalia no estado de Pernambuco. Versão N◦ 02. Pernambuco: Secretaria Estadual de Saúde; 2015.Maciel MMSA, Silva KBN, Melo JGA, Soares DM. Metodologia ativa aplicada ao ensino odontológico: um panorama nacional a partir de um estudo bibliométrico. Arch Health Invest. 2019;8(2):74-8.Morosini IAC, Otto WB, Carneiro VL, Oliveira LLRV, Oliveira DC, Ferreira FM. Profile of Brazilian scientific research in pediatric dentistry based on the 26th Annual Meeting of the SBPqO. Rev Odonto Cienc. 2012;27(2):132-36.Pontes KT, Silva EL, Macêdo Filho RA, Silva DR, Lima FJ. Estudo bibliométrico da produção científica em endodontia. Arch Health Invest. 2017;6(9):435-38.Carvalho IF, Alencar PNB, Carvalho de Andrade MD, Silva PGB, Carvalho EDF, Araújo LS et al. Clinical and x-ray oral evaluation in patients with congenital Zika Virus. J Appl Oral Sci. 2019; 27: e20180276.

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Primary care nurses’ knowledge on Zika virus infection during pregnancy

Journal of Nursing Education and Practice ◽

10.5430/jnep.v10n11p10 ◽

2020 ◽

Vol 10 (11) ◽

pp. 10

Author(s):

Paula Mikaelle Barbosa Costa ◽

Jessika Lopes Figueiredo Pereira Batista ◽

Inacia Sátiro Xavier de França ◽

Mágna Leite Pereira ◽

Millena Zaíra Cartaxo da Silva ◽

...

Keyword(s):

Primary Care ◽

Health Education ◽

Virus Infection ◽

Zika Virus ◽

Professional Training ◽

Public Health Problem ◽

Virus Infections ◽

Zika Virus Infection ◽

Primary Care Nurses ◽

Nurses Knowledge

Cases related to Zika Virus infections in Brazil have become a severe public health problem due to its relation to microcephaly and other neurological and development problems in newborn babies of mothers who were infected by the Zika virus. Nurses are vital professionals in combating this infection, both for prevention and vector control; as well as handling the target public. Therefore, the research aimed to investigate Primary Care nurses’ knowledge on Zika virus infection during pregnancy. It is a descriptive field study with qualitative approach carried out at Family Health Strategy, in the city of Cajazeiras, Paraíba, Brazil. Semi-structured interviews were conducted for data collection, which were submitted to thematic-content analysis. The nurses replied that there is not much information about Zika virus infections, and reported brain impairment as the main consequence for the newborn baby. Nurses also revealed that many women of the community showed negative feelings towards the pregnancy, and they pointed out the importance of health education actions in the community for dissemination of information on Zika virus infection control and prevention. Nurses’ contribution regarding the assistance provided to the community is considered satisfactory. However, there was a need to bring efficient and updated professional training to the reality of each community. Therefore, it is suggested that training be provided through continued health education to professionals.

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Crises convulsivas em neonato com microcefalia associada à infecção pelo Zika vírus [Seizures in newborn with microcephaly associated to Zika virus infection] [Crisis convulsivas en neonato con microcefalia asociada a la infección por el virus de Zika]

Revista Enfermagem UERJ ◽

10.12957/reuerj.2019.34029 ◽

2019 ◽

Vol 27 ◽

pp. e34029

Author(s):

Lívia Pinheiro Pereira ◽

Aglaya Oliveira Lima Cordeiro de Almeida ◽

Carla Cristina Oliveira de Jesus Lima ◽

Josely Bruce Santos ◽

Mauricio Dos Santos Barbosa ◽

...

Keyword(s):

Virus Infection ◽

Zika Virus ◽

International Debate ◽

Zika Virus Infection ◽

Raising Awareness ◽

The Family ◽

Clonic Seizures ◽

The Subject ◽

Virus Zika ◽

Family Setting

Objetivo: analisar, a partir do caso de recém-nascido com microcefalia relacionada à infecção do vírus Zika, suas características clínicas e implicações para o cuidado em saúde e enfermagem. Conteúdo: a microcefalia é uma anomalia congênita em que o perímetro cefálico é menor ou igual a 32cm. Em 2015/2016, um surto de microcefalia associado ao vírus Zika provocou um debate internacional sobre o assunto. Através de relato de caso, descrevemos os achados característicos de uma criança com microcefalia e com repercussões neurológicas graves nas primeiras 24 horas de vida. O recém-nascido, pouco após o nascimento, apresentou episódios recorrentes de convulsões tônico-clônicas que duraram cerca de três minutos. A epilepsia associada à microcefalia torna-se um agravamento, exigindo atenção especial. Conclusão: Aumentar a conscientização e sensibilizar os cuidadores é imperativo para esclarecimentos sobre a epilepsia no ambiente familiar de forma muito clara e acessível.ABSTRACTObjective: to analyze, from the case of newborn with microcephaly related to Zika virus infection, its clinical characteristics and implications for health care and nursing. Content: microcephaly is a congenital anomaly in which the cephalic perimeter (CP) is smaller than or equal to 32cm. In 2015/2016, an outbreak of microcephaly associated with the Zika virus evoked an international debate on the subject. From a case report, we analyzed and discussed findings of a child with microcephaly and with severe neurological repercussions in the first 24 hours of life. The newborn, few hours after birth, presented recurring episodes of tonic-clonic seizures lasting about three minutes. That way, epilepsy associated with microcephaly becomes an aggravation, demanding special attention. Conclusion: Raising awareness and sensitizing caregivers is imperative for clarification about epilepsy in the family setting in a very clear and accessible way.RESUMENObjetivo: analizar, a partir del caso de un recién nacido con microcefalia relacionada con la infección por el virus del Zika, sus características clínicas y sus implicaciones para el cuidado en salud y de enfermería. Contenido: la microcefalia es una anomalía congénita en la que el perímetro cefálico es menor o igual a 32cm. En 2015/2016, un brote de microcefalia asociado al virus Zika provocó un debate internacional sobre el tema. Descubrimos los hallazgos característicos de un niño con microcefalia y con repercusiones neurológicas graves. El recién nacido fue dirigido a una Unidad de Cuidados Intensivos algunas horas después del nacimiento, con episodios recurrentes de convulsiones tónico-clónicas que duraron cerca de tres minutos. De esta forma, la epilepsia asociada a la microcefalia se vuelve un agravamiento, exigiendo atención especial. Conclusión: aumentar la concienciación y sensibilizar a los cuidadores es imperativo para aclaraciones sobre la epilepsia en el ambiente familiar de forma muy clara y accesible.

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Knowledge, Awareness, and Perception of Community Pharmacists to Zika Virus Infection in Klang Valley, Malaysia

Health Services Insights ◽

10.1177/1178632920921425 ◽

2020 ◽

Vol 13 ◽

pp. 117863292092142

Author(s):

Kah Yee Lim ◽

Hong-Wai Tham

Keyword(s):

Virus Infection ◽

Zika Virus ◽

Community Pharmacists ◽

Basic Knowledge ◽

Health Concern ◽

Maximum Score ◽

Zika Virus Infection ◽

Significant Difference ◽

Level Of Knowledge ◽

Klang Valley

Background: Zika fever is a mosquito-borne disease with global health concern. It has been underreported or misdiagnosed due to its unspecific clinical manifestations, including mild-influenza like and subclinical symptoms. However, its associated serious complications which include fetal microcephaly and Guillain-Barré syndrome remained a challenge to the public health sectors. This research aimed to evaluate the knowledge, awareness, and perception toward Zika virus infection among community pharmacists in the Klang Valley of Malaysia and to determine the association between the knowledge of Zika virus infectious disease and years of community practice experience among community pharmacists in this region. Methods: This survey research was conducted from August to December 2018 through a pre-tested, self-administration, and cross-sectional random convenient sampling at various districts in the Klang Valley. A total of 275 registered community pharmacists were involved in this study by completing a pilot-tested questionnaire. Descriptive analysis, Mann-Whitney U test, and Kruskal-Wallis H test were used to analyze the data. Results: The knowledge toward Zika virus infection of respondents was classified into “poor” (5.1%), “basic” (70.9%), and “broad” (24.0%). Most of the participants (n = 195, 70.9%) presented with basic knowledge toward Zika virus infection. A total of 268 (97.5%) participants presented with high awareness toward Zika virus infection. The mean score of respondents’ knowledge and awareness was 15.88 ± 3.61 (maximum score = 28) and 13.96 ± 1.60 (maximum score = 16), respectively. There was a statistically significant difference between the years of practice of community pharmacists and the level of knowledge toward Zika virus infection. Conclusions: In conclusion, our respondents demonstrated a basic level of knowledge and high awareness toward Zika virus infection. Also, we highlighted some possible pitfalls in the knowledge of Zika virus infection, including the virus transmission, symptoms, diagnosis, treatment, prevention, and complications of the disease.

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Congenital Zika Virus Infection Paradigm: What is in the Wardrobe? A Narrative Review

East Africa Science ◽

10.24248/easci.v1i1.4 ◽

2019 ◽

Vol 1 (1) ◽

pp. 49-56

Author(s):

Mariam M. Mirambo ◽

Lucas Matemba ◽

Mtebe Majigo ◽

Stephen E. Mshana

Keyword(s):

Virus Infection ◽

Neural Tube ◽

Zika Virus ◽

English Language ◽

Case Reports ◽

Case Series ◽

Epidemiological Studies ◽

Ocular Manifestations ◽

Zika Virus Infection ◽

N 93

Background: Zika virus infection during pregnancy has been recently associated with congenital microcephaly and other severe neural tube defects. However, the magnitude of confirmed cases and the scope of these anomalies have not been extensively documented. This review focuses on the magnitude of laboratory-confirmed congenital Zika virus cases among probable cases and describing the patterns of congenital anomalies allegedly caused by the Zika virus, information which will inform further research in this area. Methods: We conducted a literature search for English-language articles about congenital Zika virus infection using online electronic databases (PubMed/MEDLINE, POPLINE, Embase, Google Scholar, and Web of Knowledge). The search terms used were, “zika”, “pregnancy”, [year], “microcephaly”, “infants”, “children”, “neonates”, “foetuses”, “neural tube defect”, and “CNS manifestations” in different combinations. All articles reporting cases or case series between January 2015 and December 2016 were included. Data were entered into a Microsoft Excel database and analysed to obtain proportions of the confirmed cases and patterns of anomalies. Results: A total of 24 articles (11 case series, 9 case reports, and 4 others) were found to be eligible and included in this review. These articles reported 919 cases, with or without microcephaly, presumed to have congenital Zika virus infection. Of these cases, 884 (96.2%) had microcephaly. Of the 884 cases of microcephaly, 783 (88.6%) were tested for Zika virus infection, and 216 (27.6%; 95% confidence interval, 24.5% to 30.8%) were confirmed to be Zika virus-positive. In addition to microcephaly, other common abnormalities reported – out of 442 cases investigated – were calcifications of brain tissue (n=240, 54.3%), ventriculomegaly (n=93, 20.8%), cerebellar hypoplasia (n=52, 11.7%), and ocular manifestations (n=46, 10.4%). Conclusion: Based on the available literature, Zika virus infection during pregnancy might lead to a wide array of outcomes other than microcephaly. There is a need for more epidemiological studies in Zika-endemic areas, particularly in Africa, to ascertain the role of Zika virus in causing congenital neurological defects.

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