Sclerotherapy for Oral Pyogenic Granuloma – A case report

First described by Hullihen in 1844, Pyogenic granuloma (PG) is a benign, exophytic vascular tumor. It is not infective, purulent or granulomatous but a reactive inflammatory mass of blood vessels with few fibroblasts within the mucosa or skin. Without any general agreement, there exist a variety of treatment options (complete surgical resection, cryosurgery, curettage, lasers etc). However, recurrence has been frequently reported. Sclerotherapy in PG (a vascular tumor) is not as commonly reported as in cases of hemangioma.Herein, we present a case of twenty-eight years old female with a clinical diagnosis of PG, treated with intralesional sodium tetradecyl sulfate (STS). Intralesional injection of 0.2 ml of undiluted STS was given for three visits between 10th of January and 21st of February 2016. The lesion healed completely at the patient’s fourth visit and recurrence was not reported till the patient was followed up for one year, i.e February 2017.

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Hemangiopericytoma of the Breast: A Case Report and a Review of the Literature

Case Reports in Oncological Medicine ◽

10.1155/2015/210643 ◽

2015 ◽

Vol 2015 ◽

pp. 1-4

Author(s):

Georgios Koukourakis ◽

Evagelos Filopoulos ◽

Kasiani Kapatou ◽

Georgios Zacharias

Keyword(s):

Case Report ◽

Frozen Section ◽

Treatment Options ◽

Vascular Tumor ◽

Needle Aspiration ◽

Biological Behavior ◽

Excision Biopsy ◽

Her Family ◽

Long Term Follow Up ◽

One Year

Introduction. Sarcomas of the breast are rare and hemangiopericytoma (HPC) of the breast is even rarer.Case Report. We report a case of a 43-year-old woman who presented with a 4 cm mass in her right breast. Her family history was positive for breast cancer. A fine needle aspiration indicated a malignant vascular tumor. An excision biopsy and frozen section analysis confirmed the presence of an encapsulated mesenchymal tumor. Its morphology and immunohistochemical marker profile were characteristic for a malignant hemangiopericytoma. Thus, she underwent a tumor excision without an axilla sampling. Approximately one year after the surgery the patient is well without local recurrence or metastasis disease to be observed. We also reviewed the literature and discuss the treatment options, characteristics, and immunophenotype of HPC.Conclusions. The accurate diagnosis of HPC depends on the appropriate histological and immunohistochemical examination. Surgical resection is the treatment of choice and due to scarcity of cases and unpredictable biological behavior of these tumors long term follow-up may be warranted.

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Pyogenic Granuloma of the Foot with Satellitosis: A Role for Conservative Management

Journal of Cutaneous Medicine and Surgery ◽

10.2310/7750.2010.09068 ◽

2011 ◽

Vol 15 (1) ◽

pp. 58-60

Author(s):

Janice Bacher ◽

Dalal Assaad ◽

David N. Adam

Keyword(s):

Differential Diagnosis ◽

Case Report ◽

Conservative Management ◽

Treatment Options ◽

Pyogenic Granuloma ◽

Conservative Approach ◽

Review Of The Literature ◽

Atypical Case ◽

Over Time ◽

Rule Out

Background: Pyogenic granuloma (PG) with satellitosis is a rare phenomenon that typically occurs in children and teenagers. It can be seen after excision or trauma to the original lesion. Objective: The aim is to review an atypical case of PG with satellitosis and to highlight a conservative approach to management. Methods: This article includes a case report of a 48-year-old woman developing PG with satellitosis in her right foot and includes a review of the literature. Results: There are few cases of PG with satellitosis in the literature. Our patient differs from most given her age and the location of the lesions. She was managed differently with a conservative observational approach, and, over time, her symptoms abated. Conclusion: PG with satellitosis can occur in varying patient populations with varying presentations. Although several treatment options exist, managing patients conservatively should be considered an approach to management. Early investigations should be conducted to rule out more sinister items in the differential diagnosis.

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Successful Complete Surgical Resection of a Large Venous Malformation of the Lower Extremity: A Case Report

Annals of Vascular Diseases ◽

10.3400/avd.cr.16-00108 ◽

2017 ◽

Vol 10 (1) ◽

pp. 59-62

Author(s):

Yohei Yamamoto ◽

Tsuyoshi Ichinose ◽

Masahiro Nakamura ◽

Masato Nishizawa ◽

Kimihiro Igari ◽

...

Keyword(s):

Case Report ◽

Lower Extremity ◽

Surgical Resection ◽

Venous Malformation ◽

Complete Surgical Resection

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The radiation therapy options of intracranial hemangiopericytoma: An overview and update on a rare vascular mesenchymal tumor

Oncology Reviews ◽

10.4081/oncol.2018.354 ◽

2018 ◽

Cited By ~ 2

Author(s):

Maria Paola Ciliberti ◽

Rosa D'Agostino ◽

Laura Gabrieli ◽

Anna Nikolaou ◽

Angela Sardaro

Keyword(s):

Surgical Resection ◽

Adjuvant Radiotherapy ◽

Therapeutic Option ◽

Treatment Options ◽

Distant Metastases ◽

Complete Resection ◽

Complete Surgical Resection ◽

Hypervascular Tumor ◽

The Central Nervous System ◽

Radiotherapy Treatment

Hemangiopericytoma (HPC) is an extremely rare hypervascular tumor of mesenchymal lineage. It tends to recur and to develop distant metastases even many years after primary surgical resection. The management of recurrent and metastatic disease is not always so well defined. A complete surgical resection does not eliminate the high risk of local recurrences that occur in the central nervous system, often in the same surgical bed. However, treatment with adjuvant radiotherapy even in cases of complete resection remains controversial. Because of its rarity, there is no standard for treatment. We focused on radiotherapy treatment options, analyzing the literature and making a base on conduct further studies to establish the standard radiation dose to be used for locoregional control of such a complex and extremely rare disease and to help specialists to take the most appropriate therapeutic option.

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Complete resolve of primary cardiac sarcoma by chemotherapy: A case report

Journal of Research in Clinical Medicine ◽

10.34172/jrcm.2021.002 ◽

2021 ◽

Vol 9 (1) ◽

pp. 2-2

Author(s):

Nasrin Gholami ◽

Sepideh Tahsini Tekantapeh

Keyword(s):

Case Report ◽

Adjuvant Chemotherapy ◽

Mortality Rate ◽

Surgical Resection ◽

Salvage Chemotherapy ◽

Cardiac Tumors ◽

Complete Surgical Resection ◽

Primary Cardiac Sarcoma ◽

Cardiac Synovial Sarcoma ◽

Primary Cardiac Tumors

Primary cardiac tumors (PCT) are rare with high mortality rate and low survival. There are several treatment approaches in the PCT management. Complete surgical resection is the main base of treatment and there is disagreement on adjuvant chemotherapy or radiotherapy after surgical resection. In this case report, complete remission of the relapsed non-metastatic cardiac synovial sarcoma was observed after salvage chemotherapy and complete surgical resection.

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Timolol for Treatment of Recalcitrant Pyogenic Granulomas: a Case Report and Review of the Literature

SKIN The Journal of Cutaneous Medicine ◽

10.25251/skin.1.3.7 ◽

2017 ◽

Vol 1 (3) ◽

pp. 150-155

Author(s):

Paige Hoyer ◽

Priscilla Ly ◽

Lindy Ross ◽

Michael Wilkerson

Keyword(s):

Current Literature ◽

Treatment Options ◽

Ophthalmic Solution ◽

Pyogenic Granuloma ◽

Vascular Tumor ◽

Current Treatment ◽

Multiple Form ◽

The Face ◽

Therapy Option ◽

A Site

Importance: Pyogenic Granuloma (PG) is a benign vascular tumor that forms commonly on the face, oral mucosa, or a site of previous injury. Though some PGs resolve spontaneously, most require some-to-multiple form(s) of treatment to prevent bleeding, ulceration, and scarring. Current treatment options for PGs include cryotherapy, laser, electrodessication, curettage or shave excision, sclerotherapy, corticosteroid injections, and imiquimod 5% cream. Timolol 0.5% ophthalmic solution has been used as a noninvasive topical treatment for PG in the pediatric population.Objective: To present a case of successful treatment of a recalcitrant PG with topical timolol, and to report on the current literature for similar cases.Case Presentation: We present a case of a 40-year-old healthy female who developed a biopsy-proven PG on her index finger. This is the first reported case to successfully use tangential biopsy and electrodessication followed by twice daily topical Timolol to treat recalcitrant PG.Conclusions: This case supports the use of 0.5% Timolol ophthalmic solution and demonstrates that it is a safe and economical therapy for adult patients with recurrent PGs. A review of the current literature is discussed, and supports timolol as an easy and economical therapy option.

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An Interesting Case Report of Frontal Sinus Keratocyst

Journal of Molecular Biology Research ◽

10.5539/jmbr.v9n1p100 ◽

2019 ◽

Vol 9 (1) ◽

pp. 100

Author(s):

Alireza Mohebbi ◽

Mohammad Aghajanpour

Keyword(s):

Case Report ◽

Surgical Resection ◽

Frontal Sinus ◽

Interesting Case ◽

Ophthalmological Examination ◽

Eyelid Edema ◽

Complete Surgical Resection ◽

Orbital Wall ◽

History Of ◽

The Right

Purpose: To report an unusual case of frontal sinus keratocyst. Case Report: A 31 year old woman presented with a history of swollen right eye and visual field impairment. The ophthalmological examination revealed right superior eyelid edema and some degrees of proptosis. CT scan with iodine injection evidenced the opacification of the right frontal sinus with superior orbital wall lysis. Complete endoscopic surgical resection of a mass containing foul smelling keratin material was performed via Draf type III. The patient became symptomatic after 6 years. Imaging studies showed neo- osteogenesis in the far lateral end of right frontal sinus. Frontal trephination was done and the remnant of keratocyst was removed and the septum interfacing the cell and the right frontal sinus was walled down entirely. Conclusion: Although frontal sinus keratocyst is benign but can spread to the surrounding structures leading to several complications. Therefore, complete surgical resection is necessary to avoid recurrence.

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Infantile hepatic haemangioendothelioma resection in a newborn: A case report and literature review

Journal of International Medical Research ◽

10.1177/0300060520934325 ◽

2020 ◽

Vol 48 (7) ◽

pp. 030006052093432

Author(s):

Xin Long ◽

Yuwei Wang ◽

Kai Zheng ◽

Bixiang Zhang

Keyword(s):

Liver Transplantation ◽

Case Report ◽

Surgical Resection ◽

Prenatal Ultrasonography ◽

Imaging Diagnosis ◽

Liver Mass ◽

Hepatic Tumour ◽

Complete Surgical Resection ◽

Additional Therapy

Infantile hepatic haemangioendothelioma (IHH) is the most common benign hepatic tumour in infants. However, experience of managing IHH is lacking and treatments for symptomatic IHH are controversial. Here we report the case of a patient with IHH treated by liver resection. A liver mass was found in a newborn by prenatal ultrasonography. The patient presented with abdominal distention with a tangible mass. Further imaging diagnosis and biopsy were carried out and complete surgical resection of the mass was performed. Histological examination confirmed IHH. The patient recovered uneventfully after surgery, with no additional therapy after discharge and no recurrence during follow-up. We also summarise previously published resected cases of IHH and review the surgical outcomes. Surgical resection and liver transplantation appear to be effective treatments for symptomatic IHH.

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