scholarly journals Antimicrobial Resistance Pattern of Bacterial Isolates Causing Urinary Tract Infection

2009 ◽  
Vol 5 (2) ◽  
pp. 49-54
Author(s):  
Padma Shrestha ◽  
S. Malla ◽  
S. Basnyat ◽  
S. Dumre ◽  
B. Upadhyay ◽  
...  

Not uploaded.Key words: Urinary tract infection; Multidrug-resistanceDOI: 10.3126/jnhrc.v5i2.2471Journal of Nepal Health Research Council (JNHRC) Vol. 5, No.2, October 2007 49-54

2018 ◽  
Vol 16 (2) ◽  
pp. 178-183
Author(s):  
Dhiraj Shrestha ◽  
Pratigya Thapa ◽  
Dinesh Bhandari ◽  
Hiramani Parajuli ◽  
Prakash Chaudhary ◽  
...  

Background: The study was designed to provide account of etiological agents of urinary tract infection in pediatric patients and the antimicrobial resistance pattern plus biofilm producing profile of the isolates.Methods: The prospective study was conducted in Alka Hospital, Nepal with 353 clean catch urine samples from children. It was obtained during July 2014 to January 2015 which were first cultured by semi-quantitative method, followed by antimicrobial susceptibility testing and biofilm production assay on Congo red agar. Multidrug- resistance, extensively drug- resistance and pandrug- resistance among isolates were considered as per international consensus.Results: Out of 353 samples, 64 (18.13%) showed positive growth in culture, confirming urinary tract infection. E. coli, 44 (68.8%) was the predominant organism followed by Klebsiella spp. 6 (14.1%). Most E. coli were sensitive to amikacin (93.2%) followed by nitrofurantoin (86.4%), and highly resistant to ampicillin (95.5%). Of 64 isolates, 23 (35.93%) were found to be multidrug- resistant strains. Biofilm was produced by 36 (56.25%) isolates.Conclusions: This study showed higher biofilm production and resistance to in-use antibiotics rendering ineffective for empirical use. Regular surveillance of resistance patterns should be done to regulate multidrug- resistant bugs and to ensure effective management of urinary tract infection in children in a tertiary care setups.Keywords: AMR; antimicrobial resistance; biofilm; urinary tract infection; UTI.


2020 ◽  
Vol 11 (6) ◽  
pp. 101-105
Author(s):  
Munyemana Jean Bosco ◽  
Bikorimana Jonas ◽  
Kantarama Evelyne ◽  
Kabanyana Pauline

Background: About 150 million people worldwide are diagnosed with urinary tract infection (UTI) every year and more than half of women get UTI at least once in their lifetimes. Overuse and misuse of antibiotics have contributed to the growing problem of resistance amongst uropathogenic bacteria making it hard to treat. Aims and Objectives: This study aimed to determine bacteria causing UTIs and their antibiotic resistance profile among patients attending Nemba District Hospital in Rwanda. Materials and Methods: A retrospective study design was used and 267 patient’s data with positive urine culture were reviewed from microbiology laboratory logbooks. Results: In this study, UTI was more frequent in female 180(67.4%) than male 87(32.6%). The most frequently isolated bacteria to cause UTI were Escherichia coli (56.93%) followed by Staphylococcus aureus (28.46%), Proteus spp. (4.49%), Klebsiella spp. (3.75%), Morganella morganii (1.87%), Coagulase Negative Staphylococcus (1.50%), Neisseria gonorrhea (1.12%), Enterobacter spp. (1.12%) and Citrobacter spp. (0.7%). There was a high antimicrobial resistance profile among bacterial isolates. The most commonly used antimicrobial agents including third-generation cephalosporin were resistant to bacterial isolates at a higher rate. Conclusion: These findings suggest continued antimicrobial resistance surveillance and special precautions should be taken for empirical treatment referring to local antimicrobial resistance.


2012 ◽  
Vol 1 (2) ◽  
pp. 60-62 ◽  
Author(s):  
Mejbah Uddin Ahmed ◽  
Md Khairuzzaman ◽  
Afroza Begum ◽  
Iftikhar Ahmed

Background: Since antibiotic resistance of uropathogens has gradually been rising, knowledge of antimicrobial resistance pattern of Escherichia coli (Esch. coli), the predominant  pathogen of urinary tract infection (UTI), is important in selecting empirical antimicrobial  therapy.Objectives: To find out the common organisms causing UTI with their antimicrobial  susceptibility pattern in Enam Medical College Hospital.Materials and Methods: This study  was carried out in the department of Microbiology, Enam Medical College Hospital, Savar,  Dhaka between January 2010 to June 2011 to see the antimicrobial resistance pattern of Esch.  coli in urine sample. A total of 512 urine samples were studied from clinically suspected UTI  cases irrespective of age and sex. Esch. coli were isolated and antibiogram of the isolates were  done.Results: The results of antibiogram revealed the resistance pattern of the isolated Esch. coli to ampicillin (93.94%), cefradine (70.71%), trimethoprim-sulfamethoxazole (48.49%),  azithromycin (41.42%), ciprofloxacin (39.40%), ceftazidime (35.56%), nitrofurantoin  (29.30%), ceftriaxone (10.11%), gentamicin (7.08%) and imipenem (3.04%).Conclusion: It  can be inferred that our findings will render useful information to clinicians in determining the  appropriately directed antimicrobial regimen when given empirically. DOI: http://dx.doi.org/10.3329/jemc.v1i2.11463 J Enam Med Col 2011; 1(2): 60-62


2017 ◽  
Vol 9 (1) ◽  
pp. 13-16
Author(s):  
Rehana Razzak Khan ◽  
Sharmeen Ahmed ◽  
A. H. Hamid Ahmed ◽  
A. S.M Nowroz ◽  
Ismet Nigar ◽  
...  

Urinary tract infection (UTI) is the most common infectious complications after renal transplantation. Recently many researchers reported that the bacterial agents of UTI in renal allograft recipients changed and demonstrated increased antimicrobial resistance to commonly used cephalosporins. This study was undertaken to isolate the bacteria which are responsible for UTI and their susceptibility pattern for appropriate antibiotic therapy in renal allograft recipients. This was an observational study conducted in the Department of Microbiology Bangabandhu Sheikh Mujib Medical University (BSMMU) from December 2010 to 2011. Twenty one renal allograft recipients from Department of Nephrology were evaluated for UTI after surgery up to six weeks. Microscopic examination, culture and sensitivity of urine specimen were performed. Out of 21 renal allograft recipients, 13 (61.90%) patients developed UTI during initial post transplant period. Of 69 urine specimens collected from them 22(31.88%) yielded positive results for culture. Enterococcus spp. (50%) was the major bacterial pathogen isolated and showed 100% resistance to Cefuroxime, Ceftriaxone and Ceftazidime. Enterococcus spp. is an emerging pathogen responsible for development of UTI in renal allograft recipients which showed 100% resistance to 2nd and 3rd genaration cephalosporin group.Bangladesh J Med Microbiol 2015; 9 (1): 13-16


Author(s):  
Sarita Otta ◽  
Bichitrananda Swain ◽  
Priyadarshini Bhoi

Background: Diabetes mellitus is a predisposing condition to different infections especially the complicated urinary tract infection (UTI). The susceptibility pattern of organisms in diabetics is different from their counterparts. So, there is always a dilemma while administering empirical regimen for UTI in diabetics. The study aims to find the common organisms implicated in the UTI in diabetic patients and their sensitivity pattern.Methods: Properly collected urine specimen from all the diabetic (cases) and non-diabetic (controls) patients included in this study was processed. Sensitivity pattern and extended spectrum beta lactamase (ESBL) production for the isolated uropathogens was noted.Results: E. coli was the most common organism isolated from both 68 cases and 85 controls in this study. Most of UTI patients with diabetes, 46 (67.7 %) had uncontrolled blood sugar level. Diabetics are more prone for catheter associated UTI (CAUTI) and fungal UTI. Most of the E coli and Atypical E coli isolated were ESBL positive for the diabetic patients (60.5%) than that for the non-diabetics (40.4%). Antimicrobial resistance pattern was similar in both the groups with maximum patients’ sensitivity to tigecycline, colistin, fosphomycin and least susceptibility to cefixime. Both E. coli and Klebsiella also showed high resistance to the fluoroquinolones.Conclusions: E. coli is the predominant uropathogen for both the diabetic & non-diabetic cases. But diabetics are more prone to get ESBL positive UTI. CAUTI and the fungal UTI are more common in diabetics. Diabetic condition does not affect the antimicrobial resistance pattern of uropathogens. But their rising resistance to fluoroquinolones, cephalosporins is a matter of concern while prescribing empiric regimen.


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