scholarly journals Incidence of Retinopathy of Prematurity and Its Association with Oxygen Therapy in Preterm Low Birth Weight Babies

2016 ◽  
Vol 35 (3) ◽  
pp. 247-252 ◽  
Author(s):  
AK Pal ◽  
Somen Sur ◽  
AK Gupta

Introduction: The objectives of this study were to study the incidence and risk factors of retinopathy of prematurity (ROP) among preterm low birth weight babies and its association with oxygen therapy.Material and Methods: During one year study period, 50 neonates, who had fulfilled the inclusion criteria (born at gestational age ≤ 35 wks), were included in the present study. They were examined by indirect ophthalmoscopy by an ophthalmologist in NICU or ophthalmology outdoor. Staging of ROP was done according to the International classification. Data obtained from this study were entered in Microsoft Excel and subsequently analysed in SPSS version 20.0.Results: Among study population, 12 neonates (24%) showed evidence of retinopathy of prematurity, and Stage 2 ROP was most common (41.7%) within this group. Those neonates who had born ≤28 wks gestational age, showed more incidence (75%) of ROP. There was significant association between ROP and prematurity, low birth weight, mechanical ventilation, duration and concentration of oxygen therapy.Conclusion: Apart from prematurity and low birth weight, oxygen therapy also carries significant risk for ROP. Thus, judicious use of oxygen in premature babies can reduce incidence of ROP significantly.J Nepal Paediatr Soc 2015;35(3):247-252

2017 ◽  
Vol 4 (4) ◽  
pp. 1193 ◽  
Author(s):  
Anoop Mantri ◽  
Mohan Makwana ◽  
Vishnu Goyal ◽  
Vikas Payal ◽  
Harish Mourya ◽  
...  

Background: Retinopathy of Prematurity (ROP) is one of the most common causes of preventable blindness in children. Recent advances in the neonatology have increased preterm survival and so has the ROP incidence. Studies all over the world and across the country have shown a wide range for incidence of ROP and so it is difficult to gauge the exact incidence, especially in our region.Methods: This prospective observational study was conducted in neonatal units of the Department of Paediatrics, Dr. S. N. Medical College, Jodhpur for a duration of six months. All newborns delivered in hospitals associated with Dr S. N. Medical College with gestation age at birth <34weeks and 34-36weeks associated with risk factors subjected to ROP screening by indirect ophthalmoscope by a trained ophthalmologist. Neonates with congenital cataract, hazy cornea, abnormal anterior chamber and those who expired or lost to follow up before sufficient examination could be done were excluded.Results: Out of 250 newborns screened, 34 (13.6%) were found positive for ROP and out of these 34, 18 (52.94%) had stage I, 11 (32.35%) had stage II, 5 (14.7%) had stage III and none for stage IV and V. Prolonged oxygen therapy, low birth weight, apnoea and sepsis were found to be significant risk factor (p<0.05) with the relative risk of 12.49, 3.71, 3.03 and 1.91 respectively.Conclusions: ROP is a preventable cause of blindness in children. Thus, its screening is indispensable and it has to be intensified in presence of risk factors such as prolonged oxygen therapy, low birth weight, apnoea and sepsis. 


2018 ◽  
Vol 5 (2) ◽  
pp. 508 ◽  
Author(s):  
Prathiba N. Doddabasappa ◽  
N. S. Mahantshetti ◽  
Mahesh Kamate ◽  
Adarsh E.

Background: Low birth weight (LBW) is one of the risk factor for neurodevelopmental delay. The present study was undertaken to assess the role of the Kangaroo Mother Care (KMC) in the neurodevelopmental outcome of low birth weight babies. Methods: The present study was undertaken at Department of Paediatrics, Jawarharlal Medical college, Belgaum during the period from January 2009 to October 2010. The study includes 80 stable LBW babies were randomized into 40 in the KMC group and 40 in convention method of care group. 36 babies in the KMC group and 33 babies in the CMC group completed the study. The Neurodevelopmental outcome was assessed by the Amiel Tison test at three, six, nine and twelfth months of age. This was compared with BSID test, at one year.Results: The neurosensory examination and passive muscle tone (PMT) were found to be abnormal. Majority of the babies in both groups has a normal neurosensory and PMT development at one year. Statistically significant to muscle tone deficit was observed in the CMC babies at six months and nine months (p = 0.005 and p = 0.013). With respect to BSID, 16 and 29 KMC babies had a normal Psychomotor Development Index (PDI) and Motor Development Index (MDI) scores when compared to 8 and 18 CMC babies (p = 0.003 and p = 0.057 respectively). Number of babies with significant delay was observed to be higher in the CMC group being 11 versus 1 for PDI scores and 4 versus 1 for MDI scores.Conclusions: The present study shows that KMC has a beneficial effect on the neurodevelopmental outcome of low birth weight babies and BSID II is a better test to detect the psychomotor and mental developmental delay when compared to the Amiel Tison test.


2017 ◽  
Vol 24 (08) ◽  
pp. 1176-1180
Author(s):  
Brig® Khalid Mehmood ◽  
Ijaz Ali ◽  
Syed Hyder Raza

Objectives: To determine the proportion of LBW Babies among those deliveredat DHQ Hospital Mirpur. Study design: Descriptive cross sectional study. Setting: DHQ hospitalMirpur AJK. Duration of study: January 2013-May 2013. Sample size: 459 deliveries. Studypopulation: women reporting in Peads OPD of DHQ hospital Mirpur AJ&K with their babiesduring study period. Sampling technique: Convenience method. Data collection tool: Datacollection Performa. Data analysis: SPSS version 14.0.Results: Out of 459 deliveriesconducted at Divisional Head Quarter hospital Mirpur, 149 cases of low birth weight babies(<2500gms) whereas the rest 310 had normal birth weight. Frequency of Low Birth Weight inmale new born babies was high, i.e ratio of male babies were 55% (82) out of 149 individualswhile females were 45% (67). Less than 37 weeks of gestational age, 37% (55) were pretermbabies and 37 – 42 weeks of gestational age, 63% (94) were full term babies.


2020 ◽  
Vol 8 (1) ◽  
pp. 58-60
Author(s):  
Mahaboob Basha Kallur ◽  
K. Muralidhar

Background: Retinopathy of prematurity (ROP) is a vaso-proliferative retinopathy which occurs mostly in premature babies. The pathological change in ROP is peripheral retinal neovascularisation which may regress completely or leave sequelae from mild myopia to bilateral total blindness. International classification of ROP helped in uniform documentation and staging of ROP. In India, the incidence of ROP is between 38 and 51.9 p.c among low-birth-weight infants. Aim & Objectives: To estimate the incidence of ROP among premature and / or low birth weight babies who were born and admitted to neonatal intensive care unit and attending neonatal follow-up clinic.Subjects and Methods:A hospital based, prospective analytical cross-sectional study was conducted in Department of Pediatrics at Shadan Institute of Medical Sciences, Teaching hospital and research center, Hyderabad, Telangana for a period of 6 months from 1st October 2018 to 31st March 2019. Prior to the study initiation, ethical clearance was obtained and written consent was taken from the parents of the respective babies. The study subjects included premature babies (less than or equal to 35 weeks of gestation) or low birth weight babies (less than or equal to 1500 grams). A predesigned, pre-tested, semi-structured proforma was used to collected the data. The data was collected, entered in Microsoft excel-2013 and analyzed using SPSS version-22 (trial). Data was presented in percentages, proportions and figures.Result:The ROP incidence in the study group was reported among 17.1 p.c of the study subjects.Conclusion:Low birth weight and prematurity are important risk factors for ROP.


2016 ◽  
Vol 10 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Seyed Ahmad Rasoulinejad ◽  
Mohammad Montazeri

Purpose: An important cause of avoidable childhood blindness is retinopathy of prematurity (ROP) in countries with high human development index and also in some emerging economies countries. To date, no research have been conducted on analyzing data of ROP prevalence in Babol, and this is the first research performed on ROP in this area. Methods: All VLBW babies who referred to Babol ophthalmology center over the seven years, from February 2007 to December 2013 were enrolled in this descriptive cross-sectional research. A team of researchers recorded patients’ information completely in check lists. A single experienced ophthalmologist performed ophthalmologic examination of patients. Result: The incidence of ROP of any stage in Babol was determined to be 306 (45%) of all babies enrolled in this study. In present study, key risk factors of ROP were low gestational age, oxygen therapy more than five days and low birth weight. Conclusion: The findings of current study demonstrate that the main risk factors of developing ROP in newborns are multiple gestation, low birth weight, oxygen therapy for more than five day. Therefore, the progression of ROP to blindness will be prevented by a high index of suspicion, suitable screening, prompt diagnosis, and early treatment.


2019 ◽  
Vol 10 (4) ◽  
pp. 5-10
Author(s):  
Zarmast Khan ◽  
Nasir Zulfiqar ◽  
Hamid Mahmood et al.

ABSTRACT:OBJECTIVE: It is very important to predict the outcome among preterm and very low birth weight babies as mortality rates are quite high. CRIB score is used to predict the outcomes in preterm neonates. The objective of this study was to determine the strength of CRIB score in detecting neonatal mortality in babies presenting with very low birth weight. STUDY DESIGN: Cross-sectional study. SUBJECTS: A total of 254 newborns with birth weight of between 500 to 1500 grams and gestational age of ≤35 weeks were included. The study was conducted over a period of 6 months in neonatology department of Shifa International Hospital, Islamabad.  METHODS: CRIB score was obtained through a prospective way in all neonates and its association was assessed with mortality during neonatal intensive care unit (NICU) stay. RESULTS: The percentage of male and female newborn subjects was 54.3% (n=138) and 45.7% (n=116) respectively. Mean gestational age was 33.3 weeks ± 1.04 and mean birth weight of study population was 1129.9 grams ± 210.6. Mean CRIB score among the study population was 6.3 ± 3.1 and overall mortality was found to be 54.7% (n=139). Mean CRIB score was found to be 8.27 ± 2.1 among mortality group and it was 3.87 ± 3.4 among newborns who were discharged (P<0.05). Mortality was present in 4.3% (n=4) of neonates with CRIB score between 1-5, 87.1% (n=121) who had CRIB score between 6-10 and 100% (n=14) of neonates who had CRIB score between 1115 (P<0.05). CONCLUSION: Significantly higher mortality was noted among neonates with higher CRIB scores.


2015 ◽  
Vol 55 (3) ◽  
pp. 142 ◽  
Author(s):  
Rina Pratiwi ◽  
Muhammad Sholeh Kosim ◽  
Noor Wijayahadi

Background Low birth weight (LBW) is closely related to neonatal morbidity and mortality. Management of LBW infants in developing countries remains limited, due to the low availability of incubators. The Kangaroo Mother Care (KMC) method has been shown to be effective for newborns, especially LBW infants, in which skin-to-skin contact may be conducive for infants’ weight gain, thermoregulation, and heart rate stability.Objective To determine the prognostic factors for KMC success in LBW babies.Methods This cohort study included LBW infants at Dr. Kariadi General Government Hospital, Semarang, by a consecutive sampling method. Success of KMC was assessed by infant weight gain, as well as stabilization of temperature, heart rate, and respiration. Prognostic factors for KMC success that we assessed were birth weight, gestational age, KMC duration, age at KMC onset and maternal education level. Statistical analyses used were Chi-square and relative risk (RR) tests.Results Of 40 LBW infants, 24 were successful in KMC. Birth weight ≥ 1500 grams (RR 0.4; 95%CI 0.23 to 0.73; P=0.001)], gestational age ≥ 34 weeks (RR 0.94; 95%CI 0.46 to 1.89; P=1.00), KMC duration ≥ 65 minutes (RR 1.44; 95%CI 0.76 to 2.75; P= 0.215), high maternal education level (RR 1.25; 95%CI 0.76 to 2.04; P=0.408), and age at KMC onset >10 days (RR 2.69; 95%CI 1.14 to 6.32; P=0.003), were factors that related to the successful of KMC.Conclusion Age at KMC onset > 10 days was a prognostic factor for KMC success in low birth weight babies.


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