Analysis of blood transfusion request and utilization pattern at teaching hospital in Eastern Nepal

Background: Blood transfusion unit collection, storage and dispatching on Birat Medical College and Teaching Hospital began from 19 June 2016 via blood bank. After which, many blood distribution were made accessible via this service. This study analyzes the blood transfusion request and utilization pattern and also to monitor for managing the bloodstocks meeting present and future demand in hospital. Materials and Methods: This is descriptive cross-sectional study conducted for all the requests of whole blood dispatched from 19th June, 2016 to 04th July, 2018. Whole blood requisitions from various departments were reviewed regarding the number of requisition, total blood unit replaced, blood group and socio-demographic profile of patients.Results: Of 648 transfusion units dispatched, 131 and 324 patients were male and female respectively, B positive blood group were most common, followed by A positive, O positive, AB positive, A negative, O negative and AB negative respectively. The largest numbers of requisitions were from Gynecology and Obstetric department in the hospital of 258 requisitions followed by internal medicine, surgery department, postoperative ward and orthopaedic department. Majority of the requisitions were for 20-29 years age group from the local district Morang. The total blood units replaced were 75, of which 29 and 46 of male and female respectively. Conclusions: B Positive was the predominant requested blood group with Gynecology and Obstetrics department making the most requests, among 20-29 years age group from Morang district. The total replaced blood units were less in number with some requisition forms even lacked essential details.

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Blood Bank Service: An Experience at Newly Established Birat Medical College and Teaching Hospital, Tankisinuwari, Morang, Nepal

Birat Journal of Health Sciences ◽

10.3126/bjhs.v2i1.17283 ◽

2017 ◽

Vol 2 (1) ◽

pp. 98-101

Author(s):

Santosh Upadhyaya Kafle ◽

K K Jha ◽

M Sigh ◽

R Rana

Keyword(s):

Blood Group ◽

Teaching Hospital ◽

Whole Blood ◽

Blood Groups ◽

Blood Bank ◽

Blood Collection ◽

Age Group ◽

Total Blood ◽

Medical College ◽

Gynecology And Obstetrics

IntroductionBlood bank service facility of blood collection, storage and dispatching began from 19 June 2016 in the new blood bank and transfusion service unit, at Birat Medical College & Teaching Hospital, Tankisinuwari, Morang, Nepal, with the support of Nepal Red Cross Society. As the supply of blood is finite, the inappropriate use of blood transfusion units and its component in the world exist, hence there is a need to monitor and regulate these services.ObjectivesThe objective of this study is to know and identify different blood groups and its utilization pattern to meet the demand for future preparedness and to identify the total blood unit, which are being, replaced back.MethodologyThis retrospective study was conducted at BMCTH, Tankisinuwari, Morang for component dispatches from 19th June, 2016 to 19th February, 2017. Requisitions for whole blood requirement for patients from various departments were reviewed regarding the department request, the whole blood requested and whether being replaced, blood group and socio-demographic profile.ResultsOut of 193 transfusion units dispatched, 28 patients were male and 165 patients were females respectively B positive blood groups were most common, followed by A positive, O positive, AB positive, both AB and O negate respectively. The largest numbers of requisitions were from Gynecology and Obstetrics ward in the hospital, while 22 requisites were from other health centers. Majority of the requisitions were for 51- 60 years age group from the local district Morang. The total number of blood units replaced were 38, out of which 5 for males and 33 for females respectively.ConclusionB positive was the predominant requested blood group, with Gynecology and Obstetrics ward demanding the most requests, among 51-60 years age group from Morang district. The total blood units being replaced were very less in number with some requisition forms, which lacked essential details.Birat Journal of Health Sciences Vol.2/No.1/Issue 2/ Jan - April 2017, Page: 98-101

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Assessment of recipients’ characteristics, transfusion appropriateness, and utilization pattern of blood and blood products in Jimma Medical Center, Jimma, Ethiopia

PLoS ONE ◽

10.1371/journal.pone.0250623 ◽

2021 ◽

Vol 16 (4) ◽

pp. e0250623

Author(s):

Tufa Feyisa ◽

Girum Tesfaye Kiya ◽

Wondimagegn Adissu Maleko

Keyword(s):

Blood Transfusion ◽

Whole Blood ◽

Medical Center ◽

Reproductive Age ◽

Blood Type ◽

Blood Component ◽

Service Improvement ◽

Total Blood ◽

Cross Sectional ◽

Blood Utilization

Background As blood transfusion remains life-saving and is being frequently prescribed, a greater number of its practice is unnecessary or inappropriate. This important clinical intervention is reported as one of the five overused medical treatments, with gross over-ordering and whole blood transfusions as the sole component being common in developing countries. Study of recipient’s demographics, clinical conditions, appropriate blood utilization, and continuous clinical audits for quality assurance and service improvement plan are important factors to this practice. This study was designed to assess the recipient’s characteristics, blood type distributions, appropriateness of blood transfusion, and utilization practice of the big medical center. Methods Institution based cross-sectional study was conducted from February 1 to June 30, 2018. Data were collected using a structured data collection format prepared for this study. All transfusion prescriptions were followed from requisition up to completion. Patient’s age, sex, requesting departments, hemodynamics, number and component of units requested and issued, and units transfused were collected. Transfusion appropriateness was assessed by a criterion-based method while blood utilization was calculated. Results A total of 545 units of blood for 425 patients were cross-matched of the 809 units of total blood prescribed. The mean and median age of transfused individuals was found to be 27.47 ±15.28 years and 26 years respectively, and 65.4% females most in reproductive age groups. O and A Rhesus-positive blood types were the two major blood groups observed. Overall 82.1% of transfusions were appropriate; while only 27.8% of patients received appropriate components as 96.5% of individuals received a whole blood transfusion. Significant blood utilization was recorded with a C/T ratio of 1.05, TP% of 100%, and TI of 1.23. Conclusion Much of the transfusion recipients were relatively young aged and females, most in the reproductive age group. Although whole blood was used as a sole component, significant blood transfusion utilization and appropriateness were recorded; while appropriate component transfusion was recorded to be significantly low. Local transfusion guidelines and appropriate component preparation and utilization are required to improve the sub-optimal blood component transfusion practice.

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Preemptive intravenous iron therapy versus autologous whole blood therapy for early postoperative hemoglobin level in patients undergoing bimaxillary orthognathic surgery: a prospective randomized noninferiority trial

BMC Oral Health ◽

10.1186/s12903-020-01359-1 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Min Suk Chae ◽

Mihyun Lee ◽

Min Ho Choi ◽

Je Uk Park ◽

Misun Park ◽

...

Keyword(s):

Blood Transfusion ◽

Blood Group ◽

Whole Blood ◽

Orthognathic Surgery ◽

Hemoglobin Level ◽

Iron Therapy ◽

Iron Group ◽

Autologous Whole Blood ◽

Bimaxillary Orthognathic Surgery ◽

Iv Iron

Abstract Background Previous studies have reported the efficacy and safety of intravenous (IV) iron therapy during the perioperative period as an alternative and adjunct to allogeneic blood transfusion. Preemptive IV iron therapy provides noninferior hemoglobin levels on postoperative day (POD) 1 compared to autologous whole blood therapy (AWBT) in healthy patients who had undergone bimaxillary orthognathic surgery. Methods This was a prospective, patient-randomized, noninferiority trial. After excluding 2 patients, 64 patients were divided into two groups: the IV iron therapy group (patients received IV iron infusion 4 weeks before surgery; n = 32) and the AWBT group (2 units of autologous whole blood were collected 4 and 2 weeks before surgery; n = 32). The primary outcome was hemoglobin level on POD 1 and the prespecified noninferiority limit was − 1 g/dL. Results Baseline data were comparable, including hemoglobin and iron levels, between the two groups. Immediately before surgery, the levels of hemoglobin, iron, and ferritin were higher in the IV iron group than in the AWBT group. The mean treatment difference (iron group—whole blood group) in hemoglobin level on POD 1 between the two groups was 0.09 (95% CI = − 0.83 to 1.0). As the lower limit of the 95% CI (− 0.83) was higher than the prespecified noninferiority margin (δ = − 1), noninferiority was established. On POD 2, the hemoglobin level became lower in the iron group, which eventually led to greater requirement of allogeneic blood transfusion compared to the whole blood group. However, the iron group did not require allogeneic blood transfusion during or early after surgery, and the whole blood group showed continuously higher incidence of overt iron deficiency compared to the iron group. Conclusion As collection of autologous whole blood caused overt iron loss and anemia before surgery and intraoperative transfusion of whole blood was not able to prevent the occurrence of persistent iron deficiency after surgery, IV iron therapy was found to have potential benefits for iron homeostasis and subsequent erythropoiesis in healthy patients early after bimaxillary orthognathic surgery. Trial registration: Clinical Research Information Service, Republic of Korea, approval number: KCT0003680 on March 27, 2019. https://cris.nih.go.kr/cris/search/search_result_st01_kren.jsp?seq=15769&sLeft=2&ltype=my&rtype=my.

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Preemptive intravenous iron therapy versus autologous whole blood therapy for early postoperative hemoglobin level in patients undergoing bimaxillary orthognathic surgery: A prospective randomized noninferiority trial

10.21203/rs.3.rs-64923/v2 ◽

2020 ◽

Author(s):

Min Suk Chae ◽

Mihyun Lee ◽

Min Ho Choi ◽

Je Uk Park ◽

Misun Park ◽

...

Keyword(s):

Blood Transfusion ◽

Blood Group ◽

Whole Blood ◽

Orthognathic Surgery ◽

Hemoglobin Level ◽

Iron Therapy ◽

Iron Group ◽

Autologous Whole Blood ◽

Bimaxillary Orthognathic Surgery ◽

Iv Iron

Abstract Background: Previous studies have reported the efficacy and safety of intravenous (IV) iron therapy during the perioperative period as an alternative and adjunct to allogeneic blood transfusion. Preemptive IV iron therapy provides noninferior hemoglobin levels on postoperative day (POD) 1 compared to autologous whole blood therapy (AWBT) in healthy patients who had undergone bimaxillary orthognathic surgery.Methods: This was a prospective, patient-randomized, noninferiority trial. After excluding 2 patients, 64 patients were divided into two groups: the IV iron therapy group (patients received IV iron infusion 4 weeks before surgery; n = 32) and the AWBT group (2 units of autologous whole blood were collected 4 and 2 weeks before surgery; n = 32). The primary outcome was hemoglobin level on POD 1 and the prespecified noninferiority limit was –1 g/dL. Results: Baseline data were comparable, including hemoglobin and iron levels, between the two groups. Immediately before surgery, the levels of hemoglobin, iron, and ferritin were higher in the IV iron group than in the AWBT group. The mean treatment difference (iron group – whole blood group) in hemoglobin level on POD 1 between the two groups was 0.09 (95% CI = –0.83 to 1.0). As the lower limit of the 95% CI (–0.83) was higher than the prespecified noninferiority margin (δ = –1), noninferiority was established. On POD 2, the hemoglobin level became lower in the iron group, which eventually led to greater requirement of allogeneic blood transfusion compared to the whole blood group. However, the iron group did not require allogeneic blood transfusion during or early after surgery, and the whole blood group showed continuously higher incidence of overt iron deficiency compared to the iron group. Conclusion: As collection of autologous whole blood caused overt iron loss and anemia before surgery and intraoperative transfusion of whole blood was not able to prevent the occurrence of persistent iron deficiency after surgery, IV iron therapy was found to have potential benefits for iron homeostasis and subsequent erythropoiesis in healthy patients early after bimaxillary orthognathic surgery.Trial registration: Clinical Research Information Service, Republic of Korea, approval number: KCT0003680 on March 27, 2019https://cris.nih.go.kr/cris/search/search_result_st01_kren.jsp?seq=15769&sLeft=2&ltype=my&rtype=my

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A study of gastrointestinal tumors at kathmandu medical college teaching hospital

Journal of Pathology of Nepal ◽

10.3126/jpn.v8i1.19455 ◽

2018 ◽

Vol 8 (1) ◽

pp. 1285-1288

Author(s):

Sailesh Bahadur Pradhan ◽

Binita Pradhan ◽

Sailuja Maharjan ◽

Prabin Bikram Thapa

Keyword(s):

Gastrointestinal Tract ◽

Teaching Hospital ◽

Histopathological Examination ◽

Benign Lesion ◽

Malignant Lesion ◽

College Teaching ◽

Age Group ◽

Benign Lesions ◽

Cross Sectional ◽

Medical College

Background: Gastrointestinal tract tumour is responsible for more cancers and death than any other cancers. The tumour in GIT include the tumour of the Oral cavity, Esophagus, Stomach, Colon, Rectum, Liver, Gallbladder, Pancreas and Biliary tree.Materials and methods: A cross sectional study was carried out among all the gastrointestinal tract tumours specimens received for histopathological examination in between January 2016 to June 2017 in Department of Pathology, Kathmandu Medical College Teaching Hospital. All tumors diagnosed either benign or malignant were included in this study. Ethical clearance was obtained from the Institutional Review Committee in KMCTH.Results: Colorectum was found to be the most commonly involved site for malignant lesion comprising 40.2% among all malignant lesions followed by stomach comprising 28.6%. Malignancy was found to be more prevalent among male with M:F ratio of 1.6:1 in colorectal region and 1.4:1 in stomach cancers. Regarding benign lesions (polyps), rectum was found to be the commonest site (57.5%), followed by colon (20.0%) and stomach, the least common site.Malignant lesions were more common among the age group of 51-60 years (37.66%) with 70.13% above 50 years. Benign lesions were also found to be the most common above 50 years comprising 40.0 percent.Conclusion: Rectum & colon was found to be the most commonly involved site for both malignant and benign lesion. Malignancy is more prevalent among male and common above 50 years of age. However, malignant cases noted in the adult age group are a matter of great concern.

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An Experience with an Outbreak of Kala-azar in a Rural Area of Bangladesh

Journal of Medicine ◽

10.3329/jom.v20i1.38817 ◽

2019 ◽

Vol 20 (1) ◽

pp. 25-28 ◽

Cited By ~ 1

Author(s):

Abdur Rahim ◽

Md. Moniruzzaman ◽

Mostofa Kamal ◽

Shah Golam Nabi ◽

Supriya Sarkar ◽

...

Keyword(s):

Linear Relationship ◽

Health Authority ◽

Significant Proportion ◽

Cross Sectional Study ◽

Age Group ◽

Sectional Study ◽

Cross Sectional ◽

Male And Female ◽

Kala Azar ◽

History Of

Background: A large number of kala-azar cases from a particular village in Debigonj upazila of Panchaghar, a remote district of Bangladesh, led us to carry out the study of the situation. Materials & methods: This cross-sectional study was done among clinically screened people at the health camp in two days in Dararhat in Debigonj upazila of Panchaghar. Results: Around 700 people were screened at the health camp and 51 (7.2%) were suspected to have either Kala-azar or related disorders where 42 (82%) were rk-39 test positive. The disease was more prevalent among adult (59.6%) and children (23.8%) under the age of 10 years. However, there was no clear linear relationship between the prevalence of the disease and age group. Kala-azar occurred in both male and female, and its prevalence did not correlate significantly with income. A history of fever (73.8%) and splenomegaly (45.2%) was noted in most of the kala-azar cases. A significant number of PKDL (26.2%) cases were also found in that area. Conclusions: Since there are a significant proportion of PKDL cases, eradication will be very tough unless the health authority take adequate measure to identify and treat them properly. J MEDICINE JUL 2019; 20 (1) : 25-28

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TYPE, TIME-TREND AND INDICATIONS OF HYSTERECTOMY

Gomal Journal of Medical Sciences ◽

10.46903/gjms/16.04.1958 ◽

2019 ◽

Vol 16 (4) ◽

pp. 92-96

Author(s):

Fauzia Anbreen ◽

Samina Qadir ◽

Hira Naeem ◽

Najma Farhat ◽

Maria Ghafoor ◽

...

Keyword(s):

Time Trend ◽

Demographic Variable ◽

Uterine Prolapse ◽

Geographical Area ◽

Age Groups ◽

Abdominal Hysterectomy ◽

Age Group ◽

Menstrual Disorders ◽

Cross Sectional ◽

Gynecology And Obstetrics

ABSTRACT Background: The frequency of hysterectomy varies in same geographical area. The objectives of this study were to determine the type, time trend and indications of hysterectomy in our population. Materials & Methods: This cross-sectional, study was conducted in the Department of Gynecology and Obstetrics, Gomal Medical College, D.I.Khan, Pakistan, from 1st January 2013 to 31st December 2016. A sample size of 571 was selected through consecutive technique. Inclusion criteria were all hysterectomies done for gynecological indications. Demographic variable was age groups. Research variables were type, time trend and indications for hysterectomy. All variables being categorical were expressed as frequency and percentages. 95% confidence interval for proportion were calculated. SPSS version 19 was used for statistical analysis. Results: Out of 571 hysterectomies, 333(58.31 %) were abdominal and 238(41.68 %) were vaginal. Age-wise distribution of hysterectomies shows >61 is the modal age group. The hysterectomy frequency increased from 7% of total gynecological admission during 2013 to 17% of total gynecological admission in 2016. The indication for hysterectomy by type from 2013-2016 was menstrual disorders and uterine prolapse. Conclusion: Trans abdominal hysterectomies were more common than vaginal hysterectomies. Most common age group for hysterectomy was older than 60 years. The indication for abdominal hysterectomy was menstrual disorders whereas the only indication for vaginal hysterectomy was uterine prolapse. Line diagram was showing an increase in hysterectomy frequency over time from 2013-16.

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Factors associated with knowledge of the nursing staff at a teaching hospital on blood transfusion

Revista Latino-Americana de Enfermagem ◽

10.1590/0104-1169.0024.2593 ◽

2015 ◽

Vol 23 (4) ◽

pp. 595-602 ◽

Cited By ~ 7

Author(s):

Jordânia Lumênia Tavares ◽

Elizabeth Barichello ◽

Ana Lúcia De Mattia ◽

Maria Helena Barbosa

Keyword(s):

Blood Transfusion ◽

Teaching Hospital ◽

Univariate Analysis ◽

Knowledge Score ◽

Simple Random Sampling ◽

Bivariate Analysis ◽

Cross Sectional ◽

Test Analysis ◽

Student’S T ◽

Nursing Professionals

AbstractObjective: to determine whether there is an association between knowledge of the nursing professionals about blood transfusion and the variables related to the professional aspects.Method: this is an observational, cross-sectional and quantitative study, carried out at a large general teaching hospital. The sample consisted of 209 nursing professionals, obtained by simple random sampling. For data collection, a checklist was used. In the univariate analysis, descriptive statistics and central trend and dispersion measures were used. In the bivariate analysis, Student's t-Test, analysis of variance and Pearson's correlation were used. To determine the predictors, multiple linear regression was applied. The Institutional Review Board (Opinion number 2434) approved the study.Results: the overall average knowledge score was 52.66%; in the Pre-transfusion Step, it corresponded to 53.38%; in the Transfusion Step 51.25% and, in the Post-transfusion Step, 62.68%. The factors related to knowledge were professional category and received training and/or guidance to accomplish the transfusion process (p<0.01).Conclusion: this study showed the influence of training and guidance on the knowledge and provided a diagnosis to identify the professionals' difficulties regarding the transfusion process.

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Safety of Family Replacement Donors vs. Voluntary Non-Remunerated Donors in Komfo Anokye Teaching Hospital, Ghana: A Comparative Study

Journal of Medical and Biomedical Sciences ◽

10.4314/jmbs.v4i1.2 ◽

2015 ◽

Vol 4 (1) ◽

pp. 11-16

Author(s):

O Addai-Mensah ◽

PA Bashiru ◽

EE Dogbe

Keyword(s):

Hepatitis B ◽

Teaching Hospital ◽

Blood Donors ◽

Blood Donation ◽

Age Groups ◽

Rapid Test ◽

Developed Countries ◽

Sub Saharan Africa ◽

Age Group ◽

Cross Sectional

Blood safety remains a challenge to many countries in sub-Saharan Africa including Ghana due to poorly planned blood donation exercises in the various communities. Blood and its products usual-ly come from two main sources; voluntary non-remunerated donors (VNRD) and family replace-ment donors (FRD). In Ghana, and in many developing countries, FRDs seem to be the major source of blood supply whilst in developed countries VNRDs are the major source. This study de-termined and compared the prevalence of four transfusion transmissible infections (TTIs); HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), and Treponema palladium (TP) among FRDs and VNRDs at the Komfo Anokye Teaching Hospital to compare the safety of blood from these two groups. This cross-sectional study was undertaken at the transfusion medicine unit (TMU) of the Komfo Anokye Teaching Hospital between March and May 2014. A total of 400 blood donors (200 FRDs and 200 VNRDs) were enrolled in this study after obtaining written informed consent. Blood samples from each of the donors were then tested for HIV, hepatitis B and C, and syphilis using rapid test kits. ABO and Rhesus blood groups were also determined for all the samples. Prev-alence of TTIs was higher among FRDs (23.5%) than in VNRDs (3.5%) with males (47) been more infected than females (7). Age group 21- 30 years was the most infected, followed by age groups 31- 40 years, 11- 20 years, 41- 50 years and 51- 60 years respectively. FRDs among the younger age group, 17- 30 years, were also more infected than their VNRD counterparts. Repeat blood donors among the VNRD group, were found to be safer than their first-time counterparts. Overall, TTIs were significantly higher in the FRD group than in the VNRD group. The prevalence rates of all the infections tested were higher in the FRD group compared to the VNRD group. FRDs were the higher risk population for TTIs in comparison to VNRDs. VNRDs should therefore be encouraged to donate blood regularly.Keywords: Transfusion Transmissible Infections, HBsAg, HCV, HIV, Treponema pallidum

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PREVALENCE OF HBV, HCV AND HIV IN BLOOD DONORS AT LIAQUETPUR

The Professional Medical Journal ◽

10.29309/tpmj/2006.13.01.5050 ◽

2006 ◽

Vol 13 (01) ◽

pp. 23-26

Author(s):

MUHAMMAD AYUB KHAN ◽

Muhammad Ashraf ◽

ABDUL REHMAN ◽

Azam Ali ◽

MUHAMMAD ASHRAF ◽

...

Keyword(s):

Hepatitis C ◽

Hepatitis B ◽

Blood Donors ◽

Cross Sectional Study ◽

Age Group ◽

Total Blood ◽

Cross Sectional ◽

Transfusion Center ◽

Blood Transfusion Center ◽

Study Setting

Objective: To know the prevalence of hepatitis B, hepatitis C and HIV.Design: Observational cross sectional study. Setting: Blood Transfusion Center Tehsil Headquarter HospitalLiaquetpur. Subjects and Methods: The data of blood donors from 2001 to 2003. Results: Total blood donors studiedwere 1426. The prevalence for hepatitis B was 5.96% (CL 4.84%-7.32%) It was 0.07% (CL <0.01% - 0.44%) for HCVand zero for HIV. The prevalence of HBV in males was 6.03% (CL 4.87%-7.45%) while 5.05% (CL 1.91%-11.63%) infemales (p=0. 6917). The prevalence in 17-20 years age group was 6.4% (CL 3.92%-10.23%), 5.81% (CL 4.6%-7.33%)in 21-40 years age group and in 41-60 years age group it was 4.35% (CL 1.33%-28.19%) [p=0.9029]. Conclusion:Hepatitis B is common, hepatitis C is an uncommon health problem while HIV is not present in this area.

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