scholarly journals Six Minute Walk Distance and Reference Equations in Normal Healthy Subjects of Nepal

2017 ◽  
Vol 13 (2) ◽  
pp. 97-101
Author(s):  
S.K. Shrestha ◽  
B. Srivastava

Background The self-paced six minute walk test is a simple assessment for sub-maximal functional capacity. It correlates well with sophisticated tests and gives good prediction for morbidity, mortality, quality of life and pulmonary functions.Objective To evaluate six minute walk distance in healthy adults to identify reference values and formulate reference equations.Method We conducted six minute walk test on 250 random volunteers at and above 18 years of age as per standard protocol. Age, gender, height and weight were measured. Pre-test and post-test vital parameters were recorded including pulse oximetry. The six minute walking distance was identified in all subjects. Multiple regression analysis was done to formulate regression equations to predict six minute walking distance. This also correlated age, gender, height, weight, body mass index with six minute walking distance.Result The mean six minute walking distance was 489±86 meters with males walking 509±82 meters and females 445±78 meters. Age, gender, weight and body mass index had significant contribution for prediction of six minute walking distance. Gender was the single most important predictor. Height had the least significance. Depending on coefficients of these variables we formulated three regression equations and tested them for accurate prediction. The two best equations were identified as: Predicted SMWD = 395–1.5xAge+2.47xWT–35.89xGender and Predicted SMWD = 440–1.82xAge–53.07xGender+5.12xBMI.Conclusion Gender, age and height are the most important predictors of six minute walking distance. Reference values and equations for both genders, different age groups with varying weights were derived for local population.

Author(s):  
James Roush ◽  
Jennifer Guy ◽  
Melissa Purvis

Purpose: This study attempted to establish reference values of the six-minute walk test (6MWT) for children (38 males; 38 females; age 90-108 months) and to determine the relationship between BMI and walking distance. Method: Subjects walked at a normal, self-selected, walking speed on a grassy field for six minutes, after which distance was measured. Results: Mean BMI was 15.50 (sd=2.00) for males and 16.30 (sd=2.90) for females. Mean walking distance was 581.70 m (sd=58.10) for males and 532.20 m (sd=52.60) for females. The partial correlation between BMI and distanced walked with the influence of gender removed was .10 (p > .05). The partial correlation between BMI and distanced walked with the influence of age removed was .02 (p > .05). There was no relationship between distance walked and BMI. Conclusions: Reference values of the six-minute walk test for healthy, third-grade school children were calculated and reported.walk test, pediatric BMI, body mass index, six minute walk test


2018 ◽  
Vol 200 ◽  
pp. 155-159 ◽  
Author(s):  
Majid Jalili ◽  
Farzad Nazem ◽  
Akbar Sazvar ◽  
Kamal Ranjbar

2014 ◽  
Vol 146 (5) ◽  
pp. S-988
Author(s):  
Jeffrey Juneau ◽  
Sudha Kodali ◽  
Talha A. Malik ◽  
Brendan M. McGuire ◽  
Winnie C. Tsai ◽  
...  

Author(s):  
Nawal S. AL-Ghamdi ◽  
Afaf A.M. Shaheen

BACKGROUND: The 6-minute walk test (6-MWT) is commonly used to measure functional capacity in clinical and research settings. The reference equations for predicting the 6-minute walk distance (6-MWD) in different populations have been established; however, there is a lack of information regarding healthy Saudi individuals over 50 years old. OBJECTIVES: This study aimed to establish the reference values of 6-MWD in a sample of healthy Saudi adults aged 50–80 years, develop regression equations for the established 6-MWD, and compare the measured 6-MWD in the present study with the predicted 6-MWD derived from the previously published regression equations. METHODS: In total, 210 healthy Saudi volunteers aged 50–80 years participated in this cross-sectional study. The 6-MWT was performed according to the American Thoracic Society (ATS) guidelines. Lung function, physical activity, blood pressure, heart rate, oxygen saturation, exertion level of leg fatigue, and sensation of dyspnea were measured. RESULTS: The mean 6-MWD was 396.2 ± 69.4 m. It was significantly correlated with age, sex, height, body mass index (BMI), and physical activity. The predictors of 6-MWD were age and BMI for men, while they were age, BMI, and height for women. They accounted for 25% and 35% of the total variance of 6-MWD for men and women, respectively. The measured 6-MWD was significantly shorter than the predicted 6-MWD. CONCLUSION: Saudi populations have significantly shorter 6-MWDs than those reported in other ethnic groups. The sex-specific equations developed in this study are expected to provide a useful measure of 6-MWT for Saudi adults. However, further investigation is required to validate the application of these equations to individuals living in different regions of Saudi Arabia.


Blood ◽  
2018 ◽  
Vol 132 (Supplement 1) ◽  
pp. 1085-1085
Author(s):  
Geoffrey Bourg ◽  
Laurence Dedeken ◽  
Phu-Quoc Le ◽  
Laurence Rozen ◽  
Safiatou Diallo ◽  
...  

Abstract The six-minute walk test (6MWT) was introduced in adults and children suffering from pulmonary or cardio-vascular conditions to assess their sub-maximal functional exercise capacity. In sickle cell disease (SCD), a reduced 6-minute walk distance was observed in adults with chronic pain, hip avascular necrosis and osteopenia ; and in children with low hemoglobin level, low fetal hemoglobin, a baseline elevated TRV. In a previous study (Dedeken et al., PLoS One 2014), we also showed that abnormal 6MWT was significantly associated with the presence of silent infarct. The aim of our study is to explore the evaluation of the 6MWT over time and to confirm the correlation with the cerebral vasculopathy in a larger cohort. This study was conducted at Hôpital Universitaire des Enfants Reine Fabiola (Brussels, Belgium) and included SCD children older than 6 years, regularly followed between 2011 and 2017 and who had at least two 6MWT. The age-standardized predicted value of the 6-minute walk distance (6MWD) was established as reported by Geiger. The 6MWT was considered as normal if the 6MWD was more than 80% of the age-standardized predicted value. Baseline hematological values, clinical events, cerebro-vascular disease, cardio-pulmonary parameters and disease-modifying treatment (DMT) were compared between those with normal and abnormal 6MWT and according to the 6MWD and between the 1st and the 2nd 6MWT overtime. 118 patients have been assessed twice and had at first evaluation a 6MWD of 90.6% (Range 49-119%), with an abnormal test found in 5.1%. The characteristics of the patients are detailed in the Table 1. The changes of the 6MWD and the biological data over time are detailed in Table 2. After 4 years of follow-up, 77.1% of patients were treated with Hydroxyurea (HU) and 16.6% patients were chronically transfused. In parallel with the increased HU prescribing rate, we have observed a significant increase of the Hb and the MCV and a decrease of reticulocytes and hemolysis parameters. The first 6WMT was performed at the median age of 10.3 years and the last one at the median age of 14.1 years. The median 6MWD increased over time including for non-chronically transfused patients. Girls performed less well in the 6MWT (93% for girls vs. 95.7% for boys; P = 0.03). Acute chest syndrome was significantly more frequent in boys (62%) compare to girls (38.7%). Nevertheless, no other differences were founded between boys and girls regarding biological values, clinical events or DMT. 26.5% of our patients have silent infarcts at a median age of 14.6 years. The 6MWD was the same in patients with and without silent infarcts (92.5% vs. 95% ; P=0.17) even when chronically transfused patients were excluded (94% vs. 95% ; P= 0.20). Patients with silent infarcts have a significant lower hemoglobin level and higher reticulocytes count, neutrophils count, LDH and MCV. In conclusion, the 6MWD observed in our cohort characterized by a very high rate of HU treatment is much higher than published in others series and improved over time. With only 5% of SCD patients having a 6MWD < 80% of the normal predicted value at last evaluation, we were not able anymore to confirm a correlation between the presence of silent infracts and abnormal 6MWT. Disclosures No relevant conflicts of interest to declare.


2013 ◽  
Vol 2 (2) ◽  
pp. 35-41
Author(s):  
Vignan Kumar Gali Prakash ◽  
Sujath Gogineni ◽  
Rajesh Kumar ◽  
Mahaboob V Shaik

Background and Aims- The six minute walk test is widely used as an outcome measure in pulmonary rehabilitation programs. The objective of this study is to report the magnitude of change in the six minute walk test with test repetition in patients with chronic obstructive pulmonary disease on pulmonary rehabilitation program. Methods: A prospective study of 51 patients with moderate to very severe COPD was carried out. Clinical examination, spirometry, six minute walk distance were done. All were advised regular follow up visits at three, six and twelve months. Results: Four (8%) very severe cases completed all visits and one in those showed improvement in Forced Expiratory Volume in 1 second by 6% and six minute walk distance by 71 metres. Seven (31.37%) severe cases completed all visits; showed improvement in Forced Expiratory Volume in 1 second by 2.5%; the distance walked was a mean 381.5 metres and this was 2.5 % improvement over base line walking distance. Six (11%) moderately severe cases completed the study; the mean distance walked at the end of the study was 451 metres, which is an improvement of 53% and the mean change in Forced expiratory volume in 1 second was <2%. Totally, the mean of modified Burden of Lung disease Dyspnoea scale was 1.7 (baseline) and 4 (after the test). Conclusions: These findings support the recommendation of practice six minute walk test at baseline assessment in order to provide an accurate measure of the effects of rehabilitation on six minute walk distance.DOI: http://dx.doi.org/10.3126/jaim.v2i2.8774 Journal of Advances in Internal Medicine 2013;02(02):35-41.


2014 ◽  
Vol 40 (3) ◽  
pp. 222-228 ◽  
Author(s):  
Maria Ângela Fontoura Moreira ◽  
Gabriel Arriola de Medeiros ◽  
Francesco Pinto Boeno ◽  
Paulo Roberto Stefani Sanches ◽  
Danton Pereira da Silva Júnior ◽  
...  

Objective: To evaluate the behavior of oxygen saturation curves throughout the six-minute walk test (6MWT) in patients with COPD. Methods: We included 85 patients, all of whom underwent spirometry and were classified as having moderate COPD (modCOPD, n = 30) or severe COPD (sevCOPD, n = 55). All of the patients performed a 6MWT, in a 27-m corridor with continuous SpO2 and HR monitoring by telemetry. We studied the SpO2 curves in order to determine the time to a 4% decrease in SpO2, the time to the minimum SpO2 (Tmin), and the post-6MWT time to return to the initial SpO2, the last designated recovery time (RT). For each of those curves, we calculated the slope. Results: The mean age in the modCOPD and sevCOPD groups was 66 ± 10 years and 62 ± 11 years, respectively. At baseline, SpO2 was > 94% in all of the patients; none received supplemental oxygen during the 6MWT; and none of the tests were interrupted. The six-minute walk distance did not differ significantly between the groups. The SpO2 values were lowest in the sevCOPD group. There was no difference between the groups regarding RT. In 71% and 63% of the sevCOPD and modCOPD group patients, respectively, a ≥ 4% decrease in SpO2 occurred within the first minute. We found that FEV1% correlated significantly with the ΔSpO2 (r = −0.398; p < 0.001), Tmin (r = −0.449; p < 0.001), and minimum SpO2 (r = 0.356; p < 0.005). Conclusions: In the sevCOPD group, in comparison with the modCOPD group, SpO2 was lower and the Tmin was greater, suggesting a worse prognosis in the former.


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