scholarly journals Blood Glucose Levels in Patients with Coronary Artery Disease

2013 ◽  
Vol 11 (1) ◽  
pp. 4-8 ◽  
Author(s):  
Ajay Rajbhandari ◽  
Dipendra Raj Pandeya ◽  
Madhur Dev Bhattarai ◽  
Ravi Malla
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Risk Factor ◽  
Blood Glucose ◽  
Coronary Artery ◽  
Fasting Glucose ◽  
Coronary Artery Diseases ◽  
Coronary Syndrome ◽  
Artery Disease

Introduction: Diabetes Mellitus is a potent risk factor for Coronary Artery Diseases, but Impaired Glucose Tolerance is increasingly known risk factor for Coronary Artery Diseases. The aim of this study was to correlate blood glucose level in the patients with Coronary Artery Diseases with Acute Coronary Syndrome and to determine the relati onship of other risk factors. Methods: This was a cross-secti onal prospecti ve study of consecutive patients admitted in coronary care unit of Bir Hospital and Shaid Gangalal National Heart Center, with diagnosis of Acute Coronary Syndrome. Results: Total 209 patients were enrolled. 90.9% (190) had dyslipidemia, 78.5% were smokers with mean Standard Deviation of duration of smoking were 25.35 years. Abnormal waist to hip ratio in male and female are 56.3% and 76.1% respectively. 14.4 % (30) had Random Blood Glucose > 200mg%, 17.2 % had Impaired Fasting Glucose (110-126 mg% World Health Organizati on); 34.4% had Impaired Fasting Glucose (100-126 mg% American Diabeti c Associati on) 28.2% had Impaired Glucose Tolerance (postprandial blood glucose 140-200mg %).19.1% were old diabetes, 21.3% had recent diabetes mellitus, 52.7% had impaired glycemia.93.1% of total patients had Glucose Intolerance of any form. Conclusions: Almost all patients had diabetic or glucose intolerance of any form prior to coronary artery disease with acute coronary syndrome. This study consisted with Asian criteria of body mass index and Waist circumference for overweight or obesity. Medical Journal of Shree Birendra Hospital; Jan-June 2012/vol.11/Issue1/4-8 DOI: http://dx.doi.org/10.3126/mjsbh.v11i1.7758

Study on Vitamin D deficiency in patients of diabetes mellitus presenting with Acute Coronary syndrome in a tertiary care hospital in South India

2020 ◽  
Vol 11 (5) ◽  
pp. 49-53
Author(s):  
Archana Bhat ◽  
Arunachalam Ramachandran ◽  
Pradeep Periera ◽  
Akshatha Rao Aroor
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Artery Disease ◽  
Vitamin D ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Vitamin D Deficiency ◽  
Coronary Syndrome ◽  
Vitamin D Levels ◽  
Luminal Stenosis ◽  
Artery Disease

Background: Vitamin D, a fat-soluble vitamin has its receptor present in myriad of tissues and it modulates multiple cellular processes. Vitamin D deficiency is reported to be associated with coronary artery disease. Cardiovascular disease is the leading cause of mortality worldwide. Aims and Objective: The primary outcome was to investigate if there is a correlation of 25-OH levels with the percentage of luminal stenosis, as measured with coronary angiogram. The secondary outcome was to determine the differences in angiographically proven luminal stenosis across categories of 25-OH vitamin D levels. Materials and Methods: Thirty patients with acute coronary syndrome with diabetes mellitus were included in this cross-sectional descriptive study. All patients were tested for fasting vitamin D levels, fasting blood sugar, HbA1C and serum creatinine. Detailed history of the patients was recorded. Data was analyzed by the statistical software SPSS version 19 and p value <0.05 was considered significant. Statistical tests like Chi- square, independent t test and log regression was used. Results: In this study 30 patients undergoing coronary angiography for acute coronary syndrome, Vitamin D levels showed severe deficiency in 6.7% (2) cases while mild deficiency was seen in 50% of the cases. Patients with single vessel disease on the coronary angiogram had lower mean HbA1C (9.18) levels in our study. Patients with triple vessel disease had poorly controlled mean HbA1C levels (10.42). Conclusion: In this study we did not find any significant difference between the serum Vitamin D deficiency levels with patients with angiographic severity of the coronary artery disease. Patients with poorly controlled diabetes mellitus had more severe angiographic proven coronary artery disease.

scholarly journals HIV as a risk factor of coronary artery disease and of acute coronary syndrome

Cor et Vasa ◽  
2017 ◽  
Vol 59 (6) ◽  
pp. e553-e556
Author(s):  
Petra Kupková ◽  
Marcel Heczko ◽  
Vladimír Kaučák ◽  
Radim Kryza
Keyword(s):  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Risk Factor ◽  
Coronary Artery ◽  
Coronary Syndrome ◽  
Artery Disease

scholarly journals Relationship between the Severity of Coronary Artery Disease and Cardiovascular Risk Factors in Acute Coronary Syndrome: Based on Tehran Heart Center’s Data Registry

2021 ◽  
Author(s):  
Negar Omidi ◽  
Saeed Sadeghian ◽  
Mojtaba Salarifar ◽  
Arash Jalali ◽  
Seyed Hesameddin Abbasi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Family History ◽  
Gensini Score ◽  
Coronary Syndrome ◽  
Artery Disease

Background: Acute coronary syndrome (ACS) is one of the main causes of mortality worldwide. We sought to evaluate the correlation between the severity of coronary artery disease (CAD) and conventional coronary artery risk factors in a large cohort of patients with ACS. Methods: This study included all patients admitted to the coronary care unit with a diagnosis of ACS between 2003 and 2017. The patients were divided into 2 groups: 1) unstable angina and 2) myocardial infarction. The aims of this study were to evaluate the effects of the risk factors and extension of coronary artery stenosis in patients with ACS according to the Gensini score. Results: Of a total 40 319 patients who presented with ACS, 18 862 patients (mean age =60.4±11.14 y, male: 67.2%) underwent conventional coronary angiography and met our criteria to enter the final analysis. The median of the Gensini score was 50 (25–88) in the study population. The multivariable analysis showed that age, sex, diabetes mellitus, hypertension, dyslipidemia, family history, cigarette smoking, opium consumption, and myocardial infarction increased the risk of positive Gensini scores. All the aforementioned risk factors, except cigarette smoking and opium consumption, increased the severity of stenosis in those with positive Gensini scores. The strongest relationship was seen vis-à-vis myocardial infarction, sex, and diabetes mellitus. Conclusion: Our findings suggest that age, sex, diabetes mellitus, dyslipidemia, hypertension, family history, and myocardial infarction have significant effects on the severity of CAD. The obesity paradox in relation to CAD should be taken into consideration and needs further investigation in patients with ACS.

scholarly journals Prevalence of type 2 diabetes mellitus and association of HbA1c with severity of coronary artery disease in patients presenting as non-diabetic acute coronary syndrome

2020 ◽  
Vol 72 (1) ◽  
Author(s):  
Mohd Iqbal Dar ◽  
Jahangir Rashid Beig ◽  
Iqra Jan ◽  
Tariq Rashid Shah ◽  
Muzaffar Ali ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Coronary Artery Disease ◽  
Type 2 Diabetes Mellitus ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Coronary Syndrome ◽  
Cardiovascular Prognosis ◽  
Artery Disease

Abstract Background Acute coronary syndrome (ACS) indicates the serious clinical manifestation of coronary artery disease (CAD) and is closely associated with cardiovascular prognosis in patients with ACS. This study was aimed to study the prevalence of type 2 diabetes mellitus (T2DM) and the relation of HbA1c with the severity of CAD in patients presenting as non-diabetic ACS. Diabetic status of the patients was assessed with fasting blood sugar (FBS) and HbA1c levels, and coronary artery disease burden was assessed by coronary angiography. Results Out of 208 patients, 85.1% were males, and 14.9% were females; 73.56% cases were hypertensive. 80.77% of cases had STEMI, 17.79% had NSTEMI, and 1.44% had unstable angina. Out of 168 STEMI patients, 64.3% were thrombolysed, 21.42% presented late, 2.38% had contraindications to thrombolysis, and 11.9% underwent primary PCI. FBS in diabetic range was found in 44.23% of cases, impaired FBS in 36.54%, and 19.23% of patients had FBS in non-diabetic range. According to HbA1c, 41.8% were diabetic, 39.4% were pre-diabetic, and 18.8% were non-diabetic. A significant positive correlation was found between HbA1c and Gensini score and between HbA1c and the number of vessels involved. Conclusion This study emphasises the importance of evaluating the presence of diabetes in patients presenting as non-diabetic acute coronary syndrome in developing countries. Acute coronary syndrome may be considered as one of the presentations of diabetes mellitus.

scholarly journals IS VITAMIN D DEFICIENCY A RISK FACTOR FOR SEVERE CORONARY ARTERY DISEASE AND ACUTE CORONARY SYNDROME

2017 ◽  
Vol 69 (11) ◽  
pp. 254 ◽  
Author(s):  
Amar N. Patnaik ◽  
Pankajkumar A. Kasar ◽  
Raju V.R.C. Pusapati ◽  
K. Jagadishbabu ◽  
Naveenkrishna Kamana ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Vitamin D ◽  
Acute Coronary Syndrome ◽  
Risk Factor ◽  
Coronary Artery ◽  
Vitamin D Deficiency ◽  
Severe Coronary Artery Disease ◽  
Coronary Syndrome ◽  
Severe Coronary Artery ◽  
Artery Disease

scholarly journals ACUTE CORONARY SYNDROME;

2017 ◽  
Vol 24 (01) ◽  
pp. 26-30
Author(s):  
Ahmed Zeeshan ◽  
Zaheer Ahmad ◽  
Ghulam Abbas Tahir ◽  
Yasir Yaqoob
Keyword(s):  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Risk Factor ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Disease Risk ◽  
Coronary Syndrome ◽  
Atherosclerotic Risk Factor ◽  
Study Duration ◽  
Artery Disease

Microalbuminuria is a strong and independent indicator of increased cardiovascularrisk among individuals with and without diabetes and hypertension. The pathophysiologicmechanism underlying the association between albumin excretion and cardiovascular disease(CVD) is that microalbuminuria can be a predictor of CVD risk as it reflects the vascular damagein kidneys. It also shows endothelial damage predicting CV disease risk. Based on this theory,periodic screening for microalbuminuria could allow early identification of vascular diseaseand help stratify overall cardiovascular risk, especially in patients with risk factors such ashypertension or diabetes. Therefore microalbuminuria can be used for stratification of risk forcardiovascular disease. Once microalbuminuria is present, cardiovascular risk factor reductionshould be aggressive. Objectives: The objective of the study was to determine the role ofmicroalbuminuria as an atherosclerotic risk factor and its association with coronary arterydisease. Study Design: Cross-sectional study. Duration of Study: Duration of study was6 months with first patient enrolled on 16-03-2007 and last patient enrolled on 15-09-2007.Setting: Medical Unit-III and CCU Allied Hospital, Faisalabad. Subjects: 300 patients withacute coronary syndrome, admitted in Allied hospital Faisalabad were enrolled. Methods: 300patients diagnosed as having acute coronary syndrome admitted in Allied hospital Faisalabad,were included in the study. Early morning urine as well as 24 hour urine had been collectedin sterilized urine bags and microalbuminuria was tested. Results: In this study 300 patientshaving acute coronary syndrome were enrolled. Microalbuminuria was positive in 66 (22%)patients and 234 (78%) patients had no microalbuminuria. There was significant associationbetween microalbuminuria and atherosclerotic coronary artery disease. Conclusion: It isconcluded that microalbuminuria is an atherosclerotic risk factor and it is strongly associatedwith coronary artery disease.

scholarly journals Risk Factor distribution in patients with Acute Coronary Syndrome

2003 ◽  
Vol 2 (2) ◽  
pp. 39-42
Author(s):  
Man Bahadur KC
Keyword(s):  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Risk Factor ◽  
Coronary Artery ◽  
South Asia ◽  
Genetic Predisposition ◽  
Life Style ◽  
South Asians ◽  
Coronary Syndrome ◽  
Artery Disease

Coronary Artery disease is emerging as a growing epidemic in whole of the South Asia region. South Asians are genatically most predisposed people to Coronary Artery disease. In this background of genetic predisposition to Coronary Artery disease and changes in life style, which increases the vulnerability to acquire this disease, many Nepalese people are getting Coronary Artery disease with increasing number every year.

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