A Comparative Clinical Evaluation of the efficacy of two Desensitizing dentifrices in Relieving Dentine Hypersensitivity

Dentinal hypersensitivity has been defined as a short, sharp pain arising from exposed dentine in response to stimuli thermal, evaporative, tactile, chemical or osmotic and which cannot be ascribed to any other form of dental defect or pathology. This is a common clinical condition which may cause patients more distress due to exposure of dentin. There are various management options for this clinical condition which can be either home applied or in office techniques. Various dentifrices are commercially available in the market. The chemical compositions of the dentifrices are different. We conducted this study to compare the effectiveness of a potassium nitrate containing dentifrice and a Novamin based dentifrice in relieving dentinal hypersensitivity. The patients were divided into two experimental groups; group 1-potassium nitrate containing dentifrice and group 2-Novamin containing dentifrice. The sensitivity score was analyzed by using a verbal rating scale at baseline, at three weeks and at six weeks after using the dentifrices. Statistical analysis was done using SPSS version 17. Chi-square test showed that there was no significant difference between the effectiveness and efficacy of the two dentifrices. The results were highly significant (p<0.001). Hence, potassium nitrate and Novamin were equally effective in reducing dentinal hypersensitivity.

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A double-blind randomized placebo-controlled study of low dose mirtazapine once daily in patients of major depressive disorders on escitalopram

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20191602 ◽

2019 ◽

Vol 8 (5) ◽

pp. 1067

Author(s):

Mallikarjuna Rao I. ◽

Usha Kiran Prayaga ◽

Dharma Rao Uppada ◽

Ramachandra Rao E. ◽

B. L. Kudagi

Keyword(s):

Depressive Disorders ◽

Low Dose ◽

Rating Scale ◽

Controlled Study ◽

P Value ◽

Chi Square ◽

Double Blind ◽

Increased Risk ◽

Significant Difference ◽

Chi Square Test

Background: The SSRIs being used as 1st line therapy in treatment of depression have delayed therapeutic effect which makes the patient vulnerable to an increased risk of suicide and decreased adherence to the treatment and will prematurely discontinue the therapy. The present study was conducted to evaluate if low dose mirtazapine-escitalopram combination therapy has any add on benefit over monotherapy with escitalopram.Methods: In a single-centered, comparative study involving patients with depression attending the out-patient after screening and exclusion, 60 eligible patients were randomly assigned to receive tablet mirtazapine 7.5 mg plus tablet escitalopram 10 mg intervention or tablet escitalopram 10 mg plus placebo intervention in a double-blind 6-week treatment phase. The primary outcome measure was the change in the 17-item Hamilton Depression Rating Scale (HDRS) and Montgomery-Asberg Depression Rating Scale (MADRS) score from baseline. Participants were evaluated at baseline, 1st, 2nd,4th and 6th week. Results were analyzed using Chi-Square test for adverse effects and independent t-test analysis for efficacy parameter.Results: In the analysis of results at 6th week the numbers of patients achieved remission in mirtazapine group are more with a p-value of 0.018 which is significant and the numbers of responders in mirtazapine group are also more which is statistically significant on chi-square test. There is no significant difference was observed between the two groups with reference to occurrence of adverse effect.Conclusions: Adding low dose mirtazapine has an added benefit in terms of efficacy and getting remission early with more number of responders in the treatment of major depression.

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Comparison of quality of obturation and instrumentation time using hand files and two rotary file systems in primary molars: A single-blinded randomized controlled trial

European Journal of Dentistry ◽

10.4103/ejd.ejd_345_16 ◽

2017 ◽

Vol 11 (03) ◽

pp. 376-379 ◽

Cited By ~ 8

Author(s):

Lavanya Govindaraju ◽

Ganesh Jeevanandan ◽

E. M. G. Subramanian

Keyword(s):

Primary Teeth ◽

Controlled Trial ◽

File Systems ◽

Pediatric Dentistry ◽

Primary Molars ◽

Chi Square ◽

Intergroup Comparison ◽

Significant Difference ◽

Group 2

ABSTRACT Objective: In permanent dentition, different rotary systems are used for canal cleaning and shaping. Rotary instrumentation in pediatric dentistry is an emerging concept. A very few studies have compared the efficiency of rotary instrumentation for canal preparation in primary teeth. Hence, this study was performed to compare the obturation quality and instrumentation time of two rotary files systems – Protaper, Mtwo with hand files in primary molars. Materials and Methods: Forty-five primary mandibular molars were randomly allotted to one of the three groups. Instrumentation was done using K-files in Group 1; Protaper in Group 2; and Mtwo in Group 3. Instrumentation time was recorded. The canal filling quality was assessed as underfill, optimal fill, and overfill. Statistical analysis was done using Chi-square, ANOVA, and post hoc Tukey test. Results: No significant difference was observed in the quality of obturation among three groups. Intergroup comparison of the instrumentation time showed a statistically significant difference between the three groups.Conclusion: The use of rotary instrumentation in primary teeth results in marked reduction in the instrumentation time and improves the quality of obturation.

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The Outcome of Pulsed Radiofrequency Treatment According to Electodiagnosis in Patients with Intractable Lumbosacral Radicular Pain

Pain Medicine ◽

10.1093/pm/pnz028 ◽

2019 ◽

Vol 20 (9) ◽

pp. 1697-1701

Author(s):

Chan Hong Park ◽

Sang Ho Lee

Keyword(s):

Rating Scale ◽

Numeric Rating Scale ◽

Failed Back Surgery Syndrome ◽

Radicular Pain ◽

Spinal Nerve ◽

Pulsed Radiofrequency ◽

Pulsed Radiofrequency Treatment ◽

Significant Difference ◽

Failed Back Surgery ◽

Group 2

AbstractBackgroundRadicular pain is related to lesions that either directly compromise the dorsal root ganglion (DRG) or indirectly compromise the spinal nerve and its roots by causing ischemia or inflammation of the axons.ObjectiveOur study aimed to assess the outcomes of pulsed readiofrequency treatment (PRF) according to electrodiagnosis results in patients with chronic intractable lumbosacral radicular pain.MethodsA total of 82 failed back surgery syndrome (FBSS) patients were included in this study. All of them underwent electromyography/nerve conduction studies before pulsed radiofrequency (PRF) treatment at the DRG, and they were classified according to the electrodiagnostic results as: group 1, no definite finding (normal); group 2, radiculopathy; and group 3, neuropathy. Pain intensity was assessed according to a numeric rating scale score and the Oswestry Disability Index (ODI) before treatment and at one, three, six, and 12 months after treatment, and successful treatment was defined as a pain score reduction of ≥50% at 12 months, as compared with the pretreatment score.ResultsPretreatment electrodiagnosis identified 28 patients with no definite findings, 31 patients with radiculopathy, and 23 patients with neuropathy. The patients with neuropathy had less pain relief after treatment than those with no definite findings and those with radiculopathy. The prevalence of pain reduction of at least 50% was lower in the neuropathy group than in the other groups. There was no statistically significant difference in ODI between group.ConclusionOutcomes after PRF at the DRG did not show strong differences according to electrodiagnostic findings in FBSS patients with chronic intractable lumbosacral radicular pain.

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Effects of Singing Songs about Preoperative Care for Tonsillectomy on the Anxiety of Children Undergoing Tonsillectomy

Nursing and Health Care ◽

10.33805/2573.3877.131 ◽

2019 ◽

pp. 17-20

Author(s):

Mohebbi Kharrati ◽

Sadat Hoseini Akram Sadat ◽

Pour Abouli Batol ◽

Kazemnejad

Keyword(s):

Rating Scale ◽

Scientific Evidence ◽

Intervention Group ◽

Routine Care ◽

Preoperative Care ◽

Operative Procedures ◽

Chi Square ◽

Significant Difference ◽

Quasi Experimental ◽

Children’S Anxiety

Introduction: Surgery creates anxiety for children, whose control and reduction are among the objectives of nursing care. Nurses have always sought scientific evidence for the use of innovative techniques appropriate for the level of understanding, recognition, and need of children, such as the use of poetry to reduce children's anxiety. Therefore, the present study aimed to investigate the effects singing songs about preoperative care for tonsillectomy on the anxiety of children undergoing tonsillectomy. Method: This quasi-experimental non-random study recruited 76 children aged 7-12 years old presenting to the hospital for tonsillectomy were selected with a convenience sampling method. In addition to the routine care, some songs were sung to children in the intervention group about pre- and post-operative procedures before, on the day of, and after the surgery. Hamilton Anxiety Rating Scale (HAM-A) was filled out before and after the surgery and on the day of discharge in the intervention and control groups in order to measure children's anxiety. Data were analyzed in SPSS software using Chi-square, Mann-Whitney, and Fisher’s exact tests. Results: The results showed that the mean and standard deviation of anxiety in both groups (control=19.57 ± 3.65; intervention=19.78 ± 4.87) were not significantly different before the intervention (P=0.48), while a significant difference (P<0.001) was observed on the day of surgery between the two groups (control=34.28 ± 5.68; intervention=26.97 ± 4.6). Conclusion: Nurses can sing songs about pre- and post-operative procedures as an easy, inexpensive way appropriate for children’s level of development to reduce their anxiety. Furthermore, the family’s engagement in pre-operative training in an innovative manner can be a step forward in the development of family-based care.

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Effectiveness of a Snoezelen Room on Fear, Anxiety, and Satisfaction of Nulliparous Women: A Randomized Controlled Trial

Iranian Journal of Psychiatry and Behavioral Sciences ◽

10.5812/ijpbs.89168 ◽

2020 ◽

Vol 14 (2) ◽

Author(s):

Mariyam Momeni ◽

Mansoureh Jamshidimanesh ◽

Hadi Ranjbar

Keyword(s):

Repeated Measures ◽

Rating Scale ◽

Controlled Trial ◽

Intervention Group ◽

Active Phase ◽

Control Group ◽

Chi Square ◽

Nulliparous Women ◽

Significant Difference ◽

Interventional Group

Background: Pregnancy and childbirth are natural phenomena in a women’s life, associated with stress and anxiety, leading to adverse effects in the mother and fetus. Using complementary medicine, such as aromatherapy, music, light radiation, and aquariums in an environment that engage a person’s multiple senses can make mothers relax through mental deviations. Objectives: The aim of this study was to evaluate the effects of a Snoezelen room on fear, anxiety, and satisfaction of childbirth’s nulliparous women. Methods: This randomized clinical trial was carried out on 130 eligible women in a selected hospital affiliated to the Iran University of Medical Sciences in Tehran. One hundred thirty women were randomly assigned to the intervention (n = 65) and control (n = 65) groups using six modes blocks using the convenient sampling method. The delivery room was designed to distract women’s minds in the intervention group. Data were collected using a demographic characteristics form, Harman’s Childbirth Attitude questionnaire (CAQ), Visual Analogue scale (VAS) to measure childbirth anxiety, and the Mackey Childbirth Satisfaction Rating scale. Data were analyzed by SPSS version 16 using independent t-test, repeated measures analysis of variance, and Bonferroni and chi-square tests. Results: The results showed a significant reduction in fear in the active phase and postpartum in the intervention group compared with the control group (P < 0.001 and P < 0.001, respectively). Anxiety showed a significant difference and was lower at dilatation of 6 to 7 and 7 to 8 cm, and after childbirth in the interventional group. The satisfaction of childbirth significantly increased in the interventional group (P < 0.001). Conclusions: These results confirmed the importance of a Snoezelen room in the childbirth of nulliparous women, which can promote vaginal childbirth.

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Effect of Training Program to Improve Observational Skills of Psychiatric Nursing Students

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2020/45354.14230 ◽

2020 ◽

Author(s):

Atallah Khalaf Alenezi

Keyword(s):

Nursing Students ◽

Training Program ◽

Rating Scale ◽

Training Programs ◽

Psychiatric Nursing ◽

Chi Square ◽

Psychiatric Institution ◽

Significant Difference ◽

Observational Skills ◽

And Performance

Introduction: Training program is believed to enhance nursing students’ knowledge and performance in observational skills, which can be an essential factor in their future practice as nurses working in a psychiatric institution. Aim: This study aimed to assess the effect of training program for psychiatric nursing students to improve their observational skills. Materials and Methods: This study used an interventional design. The study sample included 80 nursing students undergoing clinical practice in psychiatric nursing during 2019-20 (10 months). The tools used for data collection were questionnaire to assess nursing student’s knowledge and an observational checklist to measure the performance. Percentage distribution, chi-square, and correlation coefficient were used to determine influence of training program on nursing students. Results: The training program imparted to students was effective as indicated by a highly significant difference between pre/post-training programs in all items of psychiatric nursing students’ knowledge. Furthermore, a highly significant difference between pre/post-training programs in all elements of students’ observational rating scale was also evident. Conclusion: The training program improved nursing students’ knowledge and performance. Particularly, their observational skills have brought confidence in their exposure and boast their ability in caring for their patients.

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Efficacy of Lignocaine in Gel and Spray form during Buccal Infiltration Anesthesia in Children: A Randomized Clinical Trial

The Journal of Contemporary Dental Practice ◽

10.5005/jp-journals-10024-1611 ◽

2014 ◽

Vol 15 (6) ◽

pp. 750-754 ◽

Cited By ~ 5

Author(s):

Anshul Sharma ◽

BS Suprabha

Keyword(s):

Clinical Trial ◽

Randomized Clinical Trial ◽

Rating Scale ◽

Permanent Teeth ◽

Chi Square ◽

Topical Anesthetic ◽

Significant Difference ◽

Spray Form ◽

Buccal Infiltration ◽

Infiltration Anesthesia

ABSTRACT Aim To compare the efficacy of 15% lignocaine spray and 8% lignocaine gel as a topical anesthetic, in reducing pain, during buccal infiltration in children. Materials and methods Forty-two patients aged between 7 and 12 years requiring restorative procedures/extraction/pulp therapy of primary/ permanent teeth in the maxillary arch, under buccal infiltration anesthesia were selected for the study. The participants were randomly allocated into 2 groups of 21 each. In group A, 8% lignocaine gel and in group B, 15% lignocaine spray was applied prior to buccal infiltration. Pain was assessed using Wong-Baker faces pain rating scale (WBFPRS) and faces legs activity cry and consolability (FLACC) painscale. Results Pearson's chi-square test revealed that there was no significant difference in the FLACC scores of the two groups (p = 0.54). Independent t-test demonstrated that there was no significant difference in Wong-Bakers faces pain score between the two agents (p = 0.07). Conclusion There is no significant difference in the efficacy of 15% lignocaine spray and 8% lignocaine gel as a topical anesthetic in controlling pain during buccal infiltration anesthesia, in children. How to cite this article Sharma A, Suprabha BS, Shenoy R, Rao A. Efficacy of Lignocaine in Gel and Spray form during Buccal Infiltration Anesthesia in Children: A Randomized Clinical Trial. J Contemp Dent Pract 2014;15(6):750-754.

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Expression of Sigma-Class Glutathione-S-Transferase in Fetal and Pediatric Filum Terminale Samples: A Comparative Study

Medicina ◽

10.3390/medicina55050133 ◽

2019 ◽

Vol 55 (5) ◽

pp. 133

Author(s):

Cahit Kural ◽

Serpil Oguztuzun ◽

Gülçin Güler Şimşek ◽

Servet Guresci ◽

Pınar Kaygın ◽

...

Keyword(s):

Tethered Cord ◽

Filum Terminale ◽

Glutathione S Transferase ◽

Chi Square ◽

Significant Difference ◽

Chi Square Test ◽

Normal Human ◽

Group 2 ◽

The Relationship ◽

Group 1

Background and objectives: The pathophysiology of tethered cord syndrome (TCS) in children is not well elucidated. An inelastic filum terminale (FT) is the main factor underlying the stretching of the spinal cord in TCS. Our study aimed to investigate the expression of glutathione-S-transferase (GST) in children and fetal FT samples in order to understand the relationship between this enzyme expression and the development of TCS. Materials and Methods: FT samples were obtained from ten children with TCS (Group 1) and histological and immunohistochemical examinations were performed. For comparison, FT samples from fifteen normal human fetuses (Group 2) were also analyzed using the same techniques. Statistical comparison was made using a Chi-square test. Results: Positive GST-sigma expression was detected in eight (80%) of 10 samples in Group 1. The positive GST-sigma expression was less frequent in nine (60%) of 15 samples from Group 2. No statistically significant difference was detected between the two groups (p = 0.197). Conclusions: Decreased FT elasticity in TCS may be associated with increased GST expression in FT. More prospective studies are needed to clarify the mechanism of the GST–TCS relationship in children.

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1094 Depression Is Not Associated With The Presence Of Or The Severity Of Obstructive Sleep Apnea: Retrospective Study Of 841 Polysomnography Subjects

SLEEP ◽

10.1093/sleep/zsaa056.1089 ◽

2020 ◽

Vol 43 (Supplement_1) ◽

pp. A416-A416

Author(s):

K Im ◽

L Kim ◽

R Immen

Keyword(s):

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Rating Scale ◽

Numerical Rating Scale ◽

Significant Proportion ◽

Chi Square ◽

Relative Paucity ◽

Obstructive Sleep ◽

Significant Difference ◽

Chi Square Analysis

Abstract Introduction Both depression and obstructive sleep apnea (OSA) are very common medical conditions. Studies showed a co-occurrence of depression and OSA with a higher prevalence of one if the other is present. However, there is relative paucity of studies assessing the rate of depression based on the OSA severity. Methods Retrospective analysis of data collected from patients undergoing polysomnography (PSG) at an academic sleep disorders center was performed. A total of 841 subjects were included and stratified into four groups using AHI. A Chi-square analysis was applied to assess the association of varying levels of AHI and the presence of depression. Results Although a significant proportion of patients with AHI greater than 5 endorsed depression (60/165 in group with AHI 15 or greater and 115/278 in group with AHI between 5 and 15), this finding was also replicated in patients with AHI less than 5 (86/202 in AHI between 1 and 5 and 88/196 in those with AHI less than 1). As there was significant difference in rate of depression among women (54.1%) and men (26.1%) (p <0.0001), Chi-square analysis was performed for the rate of depression based on the level of AHI, adjusted for gender. In women the rate of depression from the most severe AHI to less severe AHI group were 0.48, 0.53, 0.60, and 0.53 respectively and in men it was 0.30, 0.27, 0.20, and 0.27 respectively, with no statistical difference between any groups. Conclusion Among patients who seek PSG assessment, depression appears to be more prevalent than the general public. Rate of depression is much higher among women than men in this group. However, the presence of OSA or severity of OSA does not have any correlation with the rate of depression in both women and men. These findings might be suggestive of the complexity of the association between depression and OSA. One limitation of this study is the dichotomous nature of depression (presence or absence of). The finding from this study warrants a future study utilizing a numerical rating scale of depression for severity measure to correlate it with the severity of OSA. Support NA.

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Effect of Nitrous Oxide on Pulpal Anesthesia: A Preliminary Study

Anesthesia Progress ◽

10.2344/anpr-65-02-08 ◽

2018 ◽

Vol 65 (3) ◽

pp. 156-161

Author(s):

Papimon Chompu-inwai ◽

Sophon Simprasert ◽

Patchanee Chuveera ◽

Areerat Nirunsittirat ◽

Thanapat Sastraruji ◽

...

Keyword(s):

Nitrous Oxide ◽

Rating Scale ◽

Permanent Teeth ◽

Chi Square ◽

Significant Difference ◽

Nitrous Oxide Oxygen ◽

Chi Square Test ◽

Preliminary Study ◽

Pulpal Anesthesia ◽

Irreversible Pulpitis

To compare the success of perceived pulpal anesthesia between groups using nitrous oxide/oxygen (N2O/O2) and oxygen (O2) in children premedicated with ibuprofen with symptomatic irreversible pulpitis permanent teeth. Thirty-three children (mean age 10.4 ± 1.9 years) with 33 symptomatic irreversible pulpitis permanent teeth were included in this preliminary study. All children were premedicated with ibuprofen and randomly assigned to receive either N2O/O2 (17 participants) or O2 (16 participants). Four percent articaine with epinephrine 1:100,000 was administered, and vital pulp therapy was performed. Children used the Wong-Baker FACES Pain Rating Scale (WBFPS) to report their pain at baseline as well as during carious dentin removal, pulpal exposure, and pulpal tissue removal steps. The success was determined when the reported WBFPS score was ≤4. The chi-square test was used to compare the success between both groups. The success of pulpal anesthesia was 71% (12/17) and 19% (3/16) in the N2O/O2 and O2 groups, respectively. The success in the N2O/O2 group was 52% higher than that in the O2 group (confidence interval = 22.9% to 80.7%; significant difference p = .003). From the result of this preliminary study, N2O/O2 significantly increased the success of perceived pulpal anesthesia in children premedicated with ibuprofen with symptomatic irreversible pulpitis permanent teeth. However, further study with a larger sample is required to confirm this result.

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