scholarly journals Study of PEG-6000 effect on growth and physiological parameters of China aster (Callistephus chinensis) and strawflower (Helichrysum bracteatum) in in vivo conditions

2020 ◽  
pp. 133-142
Author(s):  
N. G. Zapryanova
Keyword(s):  
Physiological Parameters ◽  
Peg 6000 ◽  
China Aster ◽  
Helichrysum Bracteatum ◽  
Effect On Growth

scholarly journals Differentiation of Acanthamoeba isolates based on the physiological parameters and in vivo experiments

2021 ◽  
Vol 39 ◽  
pp. S122
Author(s):  
Chayan Sharma ◽  
Alka Bhatia ◽  
Anchal Thakur ◽  
Amit Arora ◽  
Sumeeta Khurana
Keyword(s):  
Physiological Parameters ◽  
In Vivo Experiments

Future perspectives in in vivo quantitation of bio-physiological parameters

2004 ◽  
Vol 1264 ◽  
pp. 148-157
Author(s):  
H Iida ◽  
H Watabe ◽  
T Hayashi ◽  
N Kudomi ◽  
K.-M Kim ◽  
...  
Keyword(s):  
Physiological Parameters ◽  
Future Perspectives

BLEEDING TIME IN NORMAL SUBJECTS: ITS RELATIONSHIP WITH SEX, AGE, BLOOD GROUP, HEMATOCRIT, PLATELET COUNT AND PLASMA VON WILLEBRAND FACTOR LEVEL

1987 ◽  
Author(s):  
F Rodeghiero ◽  
G Castaman ◽  
E Di Bona ◽  
M Ruggeri
Keyword(s):  
Platelet Count ◽  
Blood Group ◽  
Von Willebrand Factor ◽  
Bleeding Time ◽  
Physiological Parameters ◽  
Factor Level ◽  
Significant Difference ◽  
Von Willebrand ◽  
Willebrand Factor

Bleeding time (BT) is the most important test for in "vivo" Vevaluation of primary hemostasis. Several physiological parameters namely sex, age, blood group, hematocrit, platelet count and von Willebrand factor level could exert a significant influenceIn this study, the relationships between BT (Simplate II,General Diagnostics)and these physiological parameters havebeen examined in 58 subjects aging 17-71 (32 males and 26 females; 26 of 0 and 32 of non-0 group). In all the subjects bleedingdiathesis was excluded by interview. They were not taking anvmedicament for at least 10 days and showed normal platelet aggregation by ADP and ArachidonateMean BT value (seconds) was 318± 65 (range 195-A95)Statistical analysis failed to show any significant difference realated to sex and blood group. There was no significant relationship with hematocrit (0.01), platelet count (−0.2A), age (−0.28) and von Willebrand factor level, mesured as ristocetin cofactor (−0.2A). In particular, our data indicate that higher von Willebrand factor levels found in non-0 group in comparison with O-group (113.3 vs 83.5, P < 0:001) do not exert any apparent influence on bleeding time

Electro-physiological parameters of hepatic radiofrequency ablation—a comparison of an in vitro versus an in vivo porcine liver model

2009 ◽  
Vol 394 (3) ◽  
pp. 503-509 ◽  
Author(s):  
R. Wahba ◽  
C. Bangard ◽  
R. Kleinert ◽  
S. Rösgen ◽  
J.-H. Fischer ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Physiological Parameters ◽  
Porcine Liver ◽  
Liver Model

An implantable ZigBee ready telemetric platform for in vivo monitoring of physiological parameters

2008 ◽  
Vol 142 (1) ◽  
pp. 369-378 ◽  
Author(s):  
Pietro Valdastri ◽  
Stefano Rossi ◽  
Arianna Menciassi ◽  
Vincenzo Lionetti ◽  
Fabio Bernini ◽  
...  
Keyword(s):  
Physiological Parameters ◽  
In Vivo Monitoring

Formulation and Characterization of Solid Dispersion Containing Capsaicin for the Treatment of Diabetes

2020 ◽  
Vol 15 (3) ◽  
pp. 219-225
Author(s):  
Tapan Kumar Giri ◽  
Payel Roy ◽  
Subhasis Maity
Keyword(s):  
Thermal Analysis ◽  
Differential Thermal Analysis ◽  
Animal Study ◽  
Solid Dispersion ◽  
Solid Dispersions ◽  
Aqueous Solubility ◽  
Peg 6000 ◽  
X Ray

Background: Chili peppers are widely used in many cuisines as a spice, and capsaicin is the main component. It has been reported that capsaicin acts as an antihyperglycemic agent. However, it shows poor aqueous solubility and bioavailability. Objective: The is to enhance the aqueous solubility and antihyperglycemic activity of capsaicin through solid dispersion formulation. Methods: Solid dispersions were prepared by the solvent evaporation method using polyethylene glycol 6000 (PEG 6000) as a hydrophilic carrier. Polymer-drug miscibility and drug crystallinity were characterized through the differential thermal analysis and X-ray powder patterns analysis. Solid dispersions were evaluated for solubility, in vitro drug dissolution and in vivo animal study in rats. Results: Results of x-ray powder patterns analysis showed a considerable reduction of drug crystallinity in solid dispersion. Differential thermal analysis result revealed a complete disappearance of capsaicin melting onset temperature in solid dispersion. From the phase solubility data, it was observed that the aqueous solubility of capsaicin was increased with increasing concentration of PEG 6000. Solid dispersion formulation showed considerable enhancement of in vitro release of drugs in comparison to pure capsaicin. In vivo animal study in rats shows that the solid dispersion containing capsaicin significantly reduced the blood glucose level in comparison to the free capsaicin. Conclusion: Higher anti-hyperglycemic effect of capsaicin loaded solid dispersion in comparison to the pure drug may be due to the enhancement of aqueous solubility of capsaicin. Thus, the solid dispersion of capsaicin showed a simple approach for capsaicin delivery with improved antidiabetic activity.

Sign in / Sign up

Export Citation Format

Share Document