scholarly journals Fractal analysis as a method of morphometric study of linear anatomical objects: modified Caliper method

2021 ◽  
Vol 27 (4) ◽  
pp. 28-34
Author(s):  
N.I. Maryenko ◽  
O.Yu. Stepanenko

The purpose of the study was to develop an original modification of the Caliper method of image fractal analysis to determine the fractal dimension of linear anatomical objects. To develop the method, the linear contour of the outer surface of the cerebral cortex was chosen as the object of study. Magnetic resonance brain images in coronal projection were used. The original modification of the Caliper method includes image analysis using Adobe Photoshop CS5 software or its analogues. The linear contour of the studied object is selected, followed by stepwise smoothing of the contour with different smoothing radius. At the 1st stage of fractal analysis smoothing is not applied, at the 2nd stage the smoothing radius is 2 pixels, the 3rd – 4 pixels, the 4th – 8 pixels, the 5th – 16 pixels. At each stage, the contour length in pixels is measured (P). The size of the fractal measurement unit (G) at the 1st stage of fractal analysis is 1 pixel, the 2nd stage – 2 pixels, the 3rd stage – 4 pixels, the 4th stage – 8 pixels, the 5th stage – 16 pixels. The contour smoothing radius, the size of the fractal measurement units and the number of stages of fractal analysis can be changed depending on the characteristics of the studied structure, size, scale and image resolution. Based on the values of the perimeter and the size of the fractal measurement units, the number of fractal measurement units covering the studied object (N) is calculated: N=P/G. The fractal dimension value is calculated based on the N and G values. The modification of the Caliper method described in this paper is automatized and does not require much time required for manual calculation. In addition, compared to the classic Caliper method, this modification is more accurate because the measurement is performed automatically. The main limitation of the developed modification is the ability to determine the fractal dimension of only closed contours of studied structures or closed linear structures, because this method involves determining the length of the closed perimeter of the selected image area. The modified Caliper method of image fractal analysis described in this paper can be used in morphology and other fields of medicine for fractal analysis of linear objects: external and internal linear contours of different anatomical structures (cerebellum, cerebral hemispheres) and pathological foci (tumors, foci of necrosis, fibrosis, etc.).

2000 ◽  
Vol 39 (02) ◽  
pp. 37-42 ◽  
Author(s):  
P. Hartikainen ◽  
J. T. Kuikka

Summary Aim: We demonstrate the heterogeneity of regional cerebral blood flow using a fractal approach and singlephoton emission computed tomography (SPECT). Method: Tc-99m-labelled ethylcysteine dimer was injected intravenously in 10 healthy controls and in 10 patients with dementia of frontal lobe type. The head was imaged with a gamma camera and transaxial, sagittal and coronal slices were reconstructed. Two hundred fifty-six symmetrical regions of interest (ROIs) were drawn onto each hemisphere of functioning brain matter. Fractal analysis was used to examine the spatial heterogeneity of blood flow as a function of the number of ROIs. Results: Relative dispersion (= coefficient of variation of the regional flows) was fractal-like in healthy subjects and could be characterized by a fractal dimension of 1.17 ± 0.05 (mean ± SD) for the left hemisphere and 1.15 ± 0.04 for the right hemisphere, respectively. The fractal dimension of 1.0 reflects completely homogeneous blood flow and 1.5 indicates a random blood flow distribution. Patients with dementia of frontal lobe type had a significantly lower fractal dimension of 1.04 ± 0.03 than in healthy controls. Conclusion: Within the limits of spatial resolution of SPECT, the heterogeneity of brain blood flow is well characterized by a fractal dimension. Fractal analysis may help brain scientists to assess age-, sex- and laterality-related anatomic and physiological changes of brain blood flow and possibly to improve precision of diagnostic information available for patient care.


2005 ◽  
Vol 1 (1) ◽  
pp. 21-24
Author(s):  
Hamid Reza Samadi

In exploration geophysics the main and initial aim is to determine density of under-research goals which have certain density difference with the host rock. Therefore, we state a method in this paper to determine the density of bouguer plate, the so-called variogram method based on fractal geometry. This method is based on minimizing surface roughness of bouguer anomaly. The fractal dimension of surface has been used as surface roughness of bouguer anomaly. Using this method, the optimal density of Charak area insouth of Hormozgan province can be determined which is 2/7 g/cfor the under-research area. This determined density has been used to correct and investigate its results about the isostasy of the studied area and results well-coincided with the geology of the area and dug exploratory holes in the text area


2021 ◽  
Vol 11 (5) ◽  
pp. 2376
Author(s):  
Sam Yu ◽  
Vasudevan Lakshminarayanan

Due to the fractal nature of retinal blood vessels, the retinal fractal dimension is a natural parameter for researchers to explore and has garnered interest as a potential diagnostic tool. This review aims to summarize the current scientific evidence regarding the relationship between fractal dimension and retinal pathology and thus assess the clinical value of retinal fractal dimension. Following the PRISMA guidelines, a literature search for research articles was conducted in several internet databases (EMBASE, MEDLINE, Web of Science, Scopus). This led to a result of 28 studies included in the final review, which were analyzed via meta-analysis to determine whether the fractal dimension changes significantly in retinal disease versus normal individuals. From the meta-analysis, summary effect sizes and 95% confidence intervals were derived for each disease category. The results for diabetic retinopathy and myopia suggest decreased retinal fractal dimension for those pathologies with the association for other diseases such as diabetes mellitus, hypertension, and glaucoma remaining uncertain. Due to heterogeneity in imaging/fractal analysis setups used between studies, it is recommended that standardized retinal fractal analysis procedures be implemented in order to facilitate future meta-analyses.


2021 ◽  
Vol 10 (9) ◽  
pp. 1804
Author(s):  
Jorge Posada-Ordax ◽  
Julia Cosin-Matamoros ◽  
Marta Elena Losa-Iglesias ◽  
Ricardo Becerro-de-Bengoa-Vallejo ◽  
Laura Esteban-Gonzalo ◽  
...  

In recent years, interest in finding alternatives for the evaluation of mobility has increased. Inertial measurement units (IMUs) stand out for their portability, size, and low price. The objective of this study was to examine the accuracy and repeatability of a commercially available IMU under controlled conditions in healthy subjects. A total of 36 subjects, including 17 males and 19 females were analyzed with a Wiva Science IMU in a corridor test while walking for 10 m and in a threadmill at 1.6 km/h, 2.4 km/h, 3.2 km/h, 4 km/h, and 4.8 km/h for one minute. We found no difference when we compared the variables at 4 km/h and 4.8 km/h. However, we found greater differences and errors at 1.6 km/h, 2.4 km/h and 3.2 km/h, and the latter one (1.6 km/h) generated more error. The main conclusion is that the Wiva Science IMU is reliable at high speeds but loses reliability at low speeds.


2013 ◽  
Vol 662 ◽  
pp. 717-720 ◽  
Author(s):  
Zhen Yu Zheng ◽  
Yan Bin Gao ◽  
Kun Peng He

As an inertial sensors assembly, the FOG inertial measurement unit (FIMU) must be calibrated before being used. The paper presents a one-time systematic IMU calibration method only using two-axis low precision turntable. First, the detail error model of inertial sensors using defined body frame is established. Then, only velocity taken as observation, system 33 state equation is established including the lever arm effects and nonlinear terms of scale factor error. The turntable experiments verify that the method can identify all the error coefficients of FIMU on low-precision two-axis turntable, after calibration the accuracy of navigation is improved.


2020 ◽  
pp. 1-8
Author(s):  
Haruhiko Yoshioka ◽  
Kouki Minami ◽  
Hirokazu Odashima ◽  
Keita Miyakawa ◽  
Kayo Horie ◽  
...  

<b><i>Objective:</i></b> The complexity of chromatin (i.e., irregular geometry and distribution) is one of the important factors considered in the cytological diagnosis of cancer. Fractal analysis with Kirsch edge detection is a known technique to detect irregular geometry and distribution in an image. We examined the outer cutoff value for the box-counting (BC) method for fractal analysis of the complexity of chromatin using Kirsch edge detection. <b><i>Materials:</i></b> The following images were used for the analysis: (1) image of the nucleus for Kirsch edge detection measuring 97 × 122 pix (10.7 × 13.4 μm) with a Feret diameter of chromatin mesh (<i>n</i> = 50) measuring 17.3 ± 1.8 pix (1.9 ± 0.5 μm) and chromatin network distance (<i>n</i> = 50) measuring 4.4 ± 1.6 pix (0.49 ± 0.18 μm), and (2) sample images for Kirsch edge detection with varying diameters (10.4, 15.9, and 18.1 μm) and network width of 0.4 μm. <b><i>Methods:</i></b> Three types of bias that can affect the outcomes of fractal analysis in cytological diagnosis were defined. (1) Nuclear position bias: images of 9 different positions generated by shifting the original position of the nucleus in the middle of a 256 × 256 pix (28.1 μm) square frame in 8 compass directions. (2) Nuclear rotation bias: images of 8 different rotations obtained by rotating the original position of the nucleus in 45° increments (0°, 45°, 90°, 135°, 180°, 225°, 270°, and 315°). (3) Nuclear size bias: images of varying size (diameter: 190 pix [10.4 μm], 290 pix [15.9 μm], and 330 pix [18.1 μm]) with the same mesh pattern (network width: 8 pix [0.4 μm]) within a 512 × 512 pix square. Different outer cutoff values for the BC method (256, 128, 64, 32, 16, and 8 pix) were applied for each bias to assess the fractal dimension and to compare the coefficient of variation (CV). <b><i>Results:</i></b> The BC method with the outer cutoff value of 32 pix resulted in the least variation of fractal dimension. Specifically, with the cutoff value of 32 pix, the CV of nuclear position bias, nuclear rotation bias, and nuclear size bias were &#x3c;1% (0.1, 0.4, and 0.3%, respectively), with no significant difference between the position and rotation bias (<i>p</i> = 0.19). Our study suggests that the BC method with the outer cutoff value of 32 pix is suitable for the analysis of the complexity of chromatin with chromatin mesh.


2016 ◽  
Vol 19 (2) ◽  
pp. 108
Author(s):  
Sugeng Widada

The Banda Sea region is an active earthquakes area which indicated by mean monthly incident of quakes more than 220. The condition is caused the area being located in the triple jucntion. Earthquakes system in this region which occur during September 2015 up to October 2016 is analyzed by fractal approach to investigate the subduction system.Earthquakes system is chaotic, so can be quantified using fractal concept. Quantify result of Banda Sea earthquakes system using Aki method is fractal dimension 2.08. It indicates that the slab was fractured by some fault in form an angle or upright possition with the subduction strike. Such a thing also be proven by the fact that the length zone of slab moved during each earthquake is not same, the variation is about 6 – 1,056 m. Based on the fractal analysis, also be identified that about 6.25 magnitute six earthquakes are expected each year. The result of study support the previous studies which propose that the tectonic system in Banda Sea region is very complex. Keywards:  Earthuakes system, fractal, Banda Sea Kawasan Laut Banda merupakan daerah aktif gempa yang ditunjukan dengan kejadian gempa rata-rata bulanan Iebih dan 220. Keadaan ini dapat dimengerti mengingat kawasan tersebut merupakan pertemuan tiga buah lempeng yang bergerak. Pola kegempaan di daerah tesebut yang tejadi pada September 2015 hingga Oktober 2016 dicoba dianalisa menggunakan pendekatan fraktal untuk mengetahui pola subduksi di daerah tersebut. Pola kegempaan merupakan suatu kejadian yang chaos, sehingga dapat dilakukan kuantisasi berdasarkan konsep fraktal. Hasil kuantisasi pola gempa Laut Banda meggunakan metode Aki diperoleh dimensi fraktal 2,08. Hal ini menunjukan bahwa slab yang menunjam dan bergerak sehingga menimbulkan gempa terbagi dalarn beberapa bagian melalui suatu sesar yang menyududut / tegak lurus jurus subduksi. Keadaan ini dikuatkan oleh hasil perhitungan panjang daerah yang bergerak untuk setiap kejadian gempa tidak sama, yaitu bervariasi dari 6 – 1.056 m. Berdasarkan analisa fraktal tersebut juga diketahui bahwa gempa dengan magnitudo 6,25 akan terjadi 6 kali dalam satu tahun. Hasil penelitian ini mendukung hasil penelitian terdahulu yang menyatakan bahwa tatanan tektonik di daerah Laut Banda sangat kompleks. Kata Kunci: Pole gempa, fraktal, Laut Banda


2015 ◽  
Vol 63 (1) ◽  
pp. 217-219
Author(s):  
C. Zych ◽  
A. Wrońska-Zych ◽  
J. Dudczyk ◽  
A. Kawalec

Abstract A two-axis gimbal system can be used for stabilizing platform equipped with observation system like cameras or different measurement units. The most important advantageous of using a gimbal stabilization is a possibility to provide not disturbed information or data from a measurement unit. This disturbance can proceed from external working conditions. The described stabilization algorithm of a gimbal system bases on a regulator with a feedback loop. Steering parameters are calculated from quaternion transformation angular velocities received from gyroscopes. This data are fed into the input of Proportional Integral Derivative (PID) controller. Their input signal is compared with earned value in the feedback loop. The paper presents the way of increasing the position’s accuracy by getting it in the feedback loop. The data fusion from a positioning sensor and a gyroscope results in much better accuracy of stabilization.


2001 ◽  
Vol 8 (5) ◽  
pp. 838-844 ◽  
Author(s):  
M.C. Lanca ◽  
J.N. Marat-Mendes ◽  
L.A. Dissado

2021 ◽  
Author(s):  
Priscila Celebrini de O. Campos ◽  
Igor Paz ◽  
Maria Esther Soares Marques ◽  
Ioulia Tchiguirinskaia ◽  
Daniel Schertzer

&lt;p&gt;The urban population growth requires an improvement in the resilient behavior of these areas to extreme weather events, especially heavy rainfall. In this context, well-developed urban planning should address the problems of infrastructure, sanitation, and installation of communities, primarily related to insufficiently gauged locations. The main objectives of this study were to analyze the impacts of in-situ rain gauges&amp;#8217; distribution associated with the elaboration of a spatial diagnosis of the occurrence of floods in the municipality of Itaperuna, Rio de Janeiro &amp;#8211; Brazil. The methodology consisted of the spatial analysis of rain gauges&amp;#8217; distribution with the help of the fractal dimension concept and investigation of flood susceptibility maps prepared by the municipality based on transitory factors (which consider precipitation in the modeling) and on permanent factors (natural flood susceptibility). Both maps were validated by the cross-tabulation method, crossing each predictive map with the recorded data of flood spots measured during a major rainfall event. The results pointed that the fractal analysis of the rain gauges&amp;#8217; distribution presented a scaling break behavior with a low fractal dimension at the small-scale range, mostly concerned in (semi-)urban catchments, highlighting the incapacity of the local instrumentation to capture the spatial rainfall variability. Thereafter, the cross-tabulation validation method indicated that the flood susceptibility map based on transitory factors presented an unsatisfactory probability of detection of floods when compared to the map based on permanent factors. These results allowed us to take into account the hydrological uncertainties concerning the insufficient gauge network and the impacts of the sparse distribution on the choice and elaboration of flood susceptibility maps that use rainfall data as input. Finally, we performed a spatial analysis to estimate the population and habitations that can be affected by floods using the flood susceptibility map based on permanent factors.&lt;/p&gt;


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