scholarly journals Immediate and long-term results of retropubic prostatectomy and simultaneous preperitoneal hernia repair in patients with benign prostatic hyperplasia and inguinal hernia

2021 ◽  
Vol 25 (4) ◽  
pp. 610-615
Author(s):  
V. O. Shaprynskyi ◽  
V. I. Gorovyi ◽  
I. V. Baralo ◽  
O. M. Kapshuk ◽  
V. G. Suleimanova ◽  
...  
Keyword(s):  
Inguinal Hernia ◽  
Benign Prostatic Hyperplasia ◽  
Hernia Repair ◽  
Comparison Group ◽  
Life Quality ◽  
Prostatic Hyperplasia ◽  
Long Term Results ◽  
General Group ◽  
Retropubic Prostatectomy

Annotation. The aim of the study was to evaluate the immediate and long-term results of valvular prostatectomy and simultaneous peritoneal hernioplasty in patients with benign prostatic hyperplasia and inguinal hernia and assess the quality of life of patients. The article presents the treatment results of 152 patients with benign prostatic hyperplasia. All individuals were divided into two groups. The general group consisted of 32 (21.1%) patients with benign prostatic hyperplasia and inguinal hernia, who underwent one-stage retropubic prostatectomy and simultaneous preperitoneal hernia repair. The comparison group consisted of 120 (78.9%) patients with benign prostatic hyperplasia who underwent only a one-stage retropubic prostatectomy. Assessment of the life quality of patients after simultaneous preperitoneal inguinal hernia repair was performed according to the EuraHS - Quality of Life scale in 6 and 12 months after surgery. The obtained quantitative data were processed by the variation statistic methods with the calculation of t-Student criteria. The data were considered reliable at a significance level of 0.95 (p<0.05). The average age of men in the comparison group was 68.0±7.2 years, in the general group – 67.1±6.9 years; the average prostate volume in the comparison group was 94.4±42.3 cm3, in the general group – 91.2±32.6 cm3; 44 (36.7%) patients of the comparison group and 4 (12.5%) patients of the general group were admitted to the department urgently (due to acute urinary retention or chronic complete urinary retention). The inguinal hernia was found in all 32 patients of the general group, among them in 4 men – on both sides. The average time of ciliary prostatectomy in the general group and in the comparison group was the same (82.8±25.6 and 80.1±17.4 minutes). The simultaneous inguinal hernia repair on the one side lasted 55.0±17.4 minutes. Neurological complications in the general group were noted in 2 (6.25%) patients, in the comparison group – in 9 (7.5%); urological complications took place in 11 (34.2%) and 40 (33.3%), respectively. The average postoperative inpatient stay in the general group was 9.5±1.7; in the comparison group – 9.8±2.9. It was statistically better due to these periods after surgery when compared with preoperative life quality.

scholarly journals THE FIRST EXPERIENCE IN THE EMBOLIZATION OF PROSTATIC ARTERIES IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA

2018 ◽  
Vol 8 (1) ◽  
pp. 28-32
Author(s):  
V. N. Pavlov ◽  
S. A. Kapranov ◽  
R. I. Safiullin ◽  
V. V. Plechev ◽  
O. V. Galimov ◽  
...  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Prostate Volume ◽  
Life Quality ◽  
Prostatic Hyperplasia ◽  
Long Term Results ◽  
Successful Operation ◽  
Chronic Urinary Retention ◽  
Medical Indications ◽  
Prostatic Artery

Introduction. Our first experience in embolization of prostatic arteries at patients with benign prostatic hyperplasia had comprised patients with the symptoms of chronic urinary retention.Material and methods. The average age of patients (n=3) was 61.0±4 years. Among medical indications to embolization there were dysuria significantly degrading the patients’ life quality and their unwillingness to proceed to transurethral resection. Before the embolization of the prostatic artery, it is necessary to identify the place of its departure and its anastomosis by computed tomography. Successful operation was effectuated without microcatheter guides in 3 cases and with the application of microcatheter guides in 3 cases. For the purposes of embolization there were used spherical embolus HydroPearl sized 400 nm. No complications were reported neither in the operational nor in the post-operational periods.Results. All patients admitted a decrease in dysuria as well as the improvement in life quality already in 7–15 days after the endovascular invasion. Control ultrasound dopplerography was performed 3 months after intervention. Two patients with embolization showed decrease of prostate volume by 26%, and one patient — by 35%.Conclusions. Embolization of the prostatic arteries is a promising low-traumatic and safe method for treating patients with benign prostatic hyperplasia. It is necessary to further study its long-term results, to develop an optimized methodology — fast, simple and cheap, but not at the expense of efficiency and safety. 

scholarly journals IMPRUVING HEMOSTASIS DURING ONESTAGE RETROPUBIC PROSTATECTOMY AND SIMULTANEUS PREPERITONEAL HERNIOPLASTIC IN PATIENTS WITH BENIGH PROSTATIC HYPERPLASIA AND INGUINAL HERNIAS

2020 ◽  
pp. 195-200
Author(s):  
V. O. Shaprinskyi ◽  
V. I. Gorovyi ◽  
O. M. Kapshuk ◽  
O. O. Vorovskyi
Keyword(s):  
Inguinal Hernia ◽  
Benign Prostatic Hyperplasia ◽  
Blood Loss ◽  
Prostatic Hyperplasia ◽  
Single Stage ◽  
Intraoperative Blood Loss ◽  
Reduce Blood Loss ◽  
Retropubic Prostatectomy ◽  
Inguinal Hernias ◽  
Duration Of Surgery

Summary. Inguinal hernia is found in 2-8% of patients with benign prostatic hyperplasia. The possibility of simultaneous elimination of prostatic obstruction and inguinal hernia requires improvement of the method of hemostasis during the performance of recumbent prostatectomy in order to reduce blood loss and time of surgery is a pressing issue for both abdominal surgery and urology. Purpose of research. Improve the method of hemostasis in the performance of one-stage prostatectomy and simultaneous preabdominal plastic of inguinal hernia in patients with benign prostatic hyperplasia and inguinal hernia to reduce blood loss and time of operation. Materials and methods of research. Preabdominal plastic of the inguinal hernia during a single-stage concurrent prostatectomy was performed for 32 patients with benign prostatic hyperplasia. The first 6 patients, preperitoneal gernioplasty was performed before retropubic prostatectomy, for the last 26 patients - after a prostatectomy because of the possibility of loosening of the applied sutures at stretching of a wound by hooks. Research and discussion of results. In order to reduce bleeding during prostate prostatectomy and time of surgery, we proposed to perform hemostatic U-shaped catgut sutures (No. 6) on the lateral surfaces of the prostate capsule on muscle pieces (pads) of the pyramidal abdominal muscle. Intraoperative blood loss during surgery was determined by weight. The application of the hemostasis technique in the performance of a single-stage concurrent prostatectomy and simultaneous preperitoneal plasticity of inguinal hernias for patients with benign prostatic hyperplasia and inguinal hernia allowed to reduce the duration of surgery by 10-15 minutes, and blood loss by 150-250 ml. Conclusions. The results of improvement of the method of hemostasis in the performance of a single-stage concurrent prostatectomy and simultaneous preperitoneal hernioplasty in patients with benign prostatic hyperplasia and inguinal hernia show a decrease in the duration of surgery and intraoperative blood loss. The use of mesh prosthesis in the performance of pre-abdominal plastics of inguinal hernias and one-time supraventricular prostatectomy allows one surgical pathology to be eliminated simultaneously with one access, to prevent recurrence of hernia, to improve the quality of life of the patient and to have economic justification.

The first experience of bipolar transurethral operations in surgery of benign prostatic hyperplasia

2018 ◽  
pp. 10-20
Author(s):  
Н.А. Глотов ◽  
Н.Е. Соколов ◽  
Ю.Б. Смоляков
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Prostatic Hyperplasia ◽  
Medium Term ◽  
Significance Level ◽  
The Road ◽  
Surgical Methods ◽  
The Comparative Study ◽  
Endoscopic Methods ◽  
Qualitative Characteristics

Представлены результаты внедрения в хирургическую практику урологического отделения Дорожной клинической больницы г. Ярославль биполярной техники трансуретральной резекции (БТУР) и энуклеации простаты (ТУЭБ) для лечения доброкачественной гиперплазии предстательной железы (ДГПЖ) средних и больших размеров. В сравнительное исследование включено 164 пациента, разделенных по методам операции на 2 основные группы (ТУЭБ - 33 человека, БТУР - 49) и 2 контрольные (открытая простатэктомия - ОПЭ - 38 и монополярная ТУР - 44). Для новых эндоскопических методов установлено значимое снижение объема кровопотери, частоты геморрагических осложнений, сроков послеоперационной катетеризации и госпитализации. Для количественной оценки различий средних и относительных показателей использо-вали непараметрический критерий Манна-Уитни, оценка качественных признаков проводилась с применением критерия Пирсона (χ2), уровень значимости различий для исследования выбран р ≤ 0,05. Анализ послеоперационной динамики клинических показателей в среднесрочной перспективе показал сходную радикальность и эффектив-ность сравниваемых методов. Установленные меньшая инвазивность, большая безопасность и лучшая переносимость биполярных эндоскопических операций демонстрируют перспективность их внедрения взамен бывших стандартных хирургических методов, что позволит повысить качество оперативного лечения и сократить затраты стационара. The results of the introduction into surgical practice of the urological Department of the road clinical hospital of Yaroslavl bipolar technique of transurethral resection (BTTR) and enucleation of the prostate (EOTP) for the treatment of benign prostatic hyperplasia (BPH) of medium and large sizes are presented. The comparative study included 164 patients, divided by the methods of surgery into 2 main groups (EOTP - 33 people, BTTR - 49) and 2 control (open prostatectomy - OPE - 38 and monopolar TTR - 44). For new endoscopic methods, a significant reduction in the volume of blood loss, the frequency of hemorrhagic complications, the timing of postoperative catheterization and hospitalization was established. Nonparametric Mann-Whitney test was used to quantify the differences in mean and relative indicators, qualitative characteristics were evaluated using Pearson test (χ2), the significance level of the differences for the study was chosen p ≤ 0.05. Analysis of postoperative dynamics of clinical parameters in the medium term showed similar radicality and effectiveness of the compared methods. The lower invasiveness, greater safety and better tolerability of bipolar endoscopic operations demonstrate the prospects of their implementation instead of the former standard surgical methods, which will improve the quality of surgical treatment and reduce the costs of the hospital.

scholarly journals The Etiology and Pathophysiology Genesis of Benign Prostatic Hyperplasia and Prostate Cancer: A New Perspective

Medicines ◽  
2021 ◽  
Vol 8 (6) ◽  
pp. 30
Author(s):  
Teow J. Phua
Keyword(s):  
Prostate Cancer ◽  
Benign Prostatic Hyperplasia ◽  
Cell Biology ◽  
Cancer Biology ◽  
Cost Savings ◽  
Prostatic Hyperplasia ◽  
Biological Processes ◽  
New Perspective ◽  
Prostatic Diseases

Background: The etiology of benign prostatic hyperplasia and prostate cancer are unknown, with ageing being the greatness risk factor. Methods: This new perspective evaluates the available interdisciplinary evidence regarding prostate ageing in terms of the cell biology of regulation and homeostasis, which could explain the timeline of evolutionary cancer biology as degenerative, inflammatory and neoplasm progressions in these multifactorial and heterogeneous prostatic diseases. Results: This prostate ageing degeneration hypothesis encompasses the testosterone-vascular-inflamm-ageing triad, along with the cell biology regulation of amyloidosis and autophagy within an evolutionary tumorigenesis microenvironment. Conclusions: An understanding of these biological processes of prostate ageing can provide potential strategies for early prevention and could contribute to maintaining quality of life for the ageing individual along with substantial medical cost savings.

scholarly journals Pharmacological Effects and Potential Clinical Usefulness of Polyphenols in Benign Prostatic Hyperplasia

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 450
Author(s):  
Kensuke Mitsunari ◽  
Yasuyoshi Miyata ◽  
Tomohiro Matsuo ◽  
Yuta Mukae ◽  
Asato Otsubo ◽  
...  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Molecular Mechanisms ◽  
Prostatic Hyperplasia ◽  
Pathological Conditions ◽  
Urinary Tract Symptoms ◽  
Anti Inflammatory ◽  
Lower Urinary

Benign prostatic hyperplasia (BPH) is arguably the most common benign disease among men. This disease is often associated with lower urinary tract symptoms (LUTS) in men and significantly decreases the quality of life. Polyphenol consumption reportedly plays an important role in the prevention of many diseases, including BPH. In recent years, in addition to disease prevention, many studies have reported the efficacy and safety of polyphenol treatment against various pathological conditions in vivo and in vitro. Furthermore, numerous studies have also revealed the molecular mechanisms of the antioxidant and anti-inflammatory effects of polyphenols. We believe that an improved understanding of the detailed pharmacological roles of polyphenol-induced activities at a molecular level is important for the prevention and treatment of BPH. Polyphenols are composed of many members, and their biological roles differ. In this review, we first provide information regarding the pathological roles of oxidative stress and inflammation in BPH. Next, the antioxidant and anti-inflammatory effects of polyphenols, including those of flavonoids and non-flavonoids, are discussed. Finally, we talk about the results and limitations of previous clinical trials that have used polyphenols in BPH, with particular focus on their molecular mechanisms of action.

Long-Term Effects of Doxazosin, Finasteride and Combination Therapy on Quality of Life in Men with Benign Prostatic Hyperplasia

2013 ◽  
Vol 190 (1) ◽  
pp. 187-193 ◽  
Author(s):  
Chyng-Wen Fwu ◽  
Paul W. Eggers ◽  
Steven A. Kaplan ◽  
Ziya Kirkali ◽  
Jeannette Y. Lee ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Benign Prostatic Hyperplasia ◽  
Combination Therapy ◽  
Prostatic Hyperplasia ◽  
Long Term Effects
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