Use of Masks as a Preventative Public Health Strategy to Limit the Spread of COVID-19

2021 ◽  
pp. 1-5
Author(s):  
Wally Bartfay ◽  
Wally Bartfay ◽  
Marina Ali
Keyword(s):  
Public Health ◽  
Single Layer ◽  
Global Perspective ◽  
Contact Tracing ◽  
Global Pandemic ◽  
Health Strategy ◽  
Preventative Strategy ◽  
Viral Dose ◽  
Public Health Strategies ◽  
Health Experts

SARS-CoV-2 coronavirus (COVID-19) is a respiratory infectious disease that has caused a global pandemic of unprecedented proportions. There has been a lot of discussion and debate in social media and by public health experts about the effectiveness of masks as a preventative strategy to decrease transmission of this virus. There are two modes in which mask may be beneficial: i) To serve as a physical barrier against the virus entering or leaving the oral-nasal passages of mask wearers, and ii) to decrease the risk that the person wearing the mask might pass the virus on to someone else (e.g., via coughing). The focus of this review is on the efficacy of different masks-types, and their demonstrated effectiveness in mitigating transmission from a global perspective. Our findings reveal that the use of commercially manufactured mask greatly decreases the distribution of COVID-19, whereas single layer homemade masks also provide protection by decreasing the viral dose of exposure and limit outward aerosol particle emissions. We argue that masks are a critical component in the arsenal of public health strategies to decrease transmission of viruses, including handwashing, maintaining social distancing (2 meters), limiting large gatherings of people, isolation of suspected cases, screening, and contact tracing.

scholarly journals Spatiotemporal patterns and progression of the Delta variant of COVID-19 and their health intervention linkages in Southeast Asia

2021 ◽  
Author(s):  
Wei Luo ◽  
Zhaoyin Liu ◽  
Yuxuan Zhou ◽  
Yumin Zhao ◽  
Yunyue Elita Li ◽  
...  
Keyword(s):  
Public Health ◽  
Southeast Asia ◽  
Spatiotemporal Analysis ◽  
Health Interventions ◽  
Disease Spread ◽  
Epidemic Dynamics ◽  
Health Measures ◽  
Global Pandemic ◽  
Public Health Strategies ◽  
Time Scan

The global pandemic of COVID-19 presented an unprecedented challenge to all countries in the world, among which Southeast Asia (SEA) countries managed to maintain and mitigate the first wave of COVID-19 in 2020. However, these countries were caught in the crisis after the Delta variant was introduced to SEA, though many countries had immediately implemented non-pharmaceutical intervention (NPI) measures along with vaccination in order to contain the disease spread. To investigate the potential linkages between epidemic dynamics and public health interventions, we adopted a prospective space-time scan method to conduct spatiotemporal analysis at the district level in the seven selected countries in SEA from June 2021 to October 2021. Results reveal the spatial and temporal propagation and progression of COVID-19 risks relative to public health measures implemented by different countries. Our research benefits continuous improvements of public health strategies in preventing and containing this pandemic.

scholarly journals Weekly COVID-19 testing with household quarantine and contact tracing is feasible and would probably end the epidemic

2020 ◽  
Vol 7 (6) ◽  
pp. 200915 ◽  
Author(s):  
Julian Peto ◽  
James Carpenter ◽  
George Davey Smith ◽  
Stephen Duffy ◽  
Richard Houlston ◽  
...  
Keyword(s):  
Public Health ◽  
Demonstration Project ◽  
Contact Tracing ◽  
Normal Life ◽  
Household Members ◽  
Health Experts

The COVID-19 epidemic can probably be ended and normal life restored, perhaps quite quickly, by weekly SARS-CoV-2 RNA testing together with household quarantine and systematic contact tracing. Isolated outbreaks could then be contained by contact tracing, supplemented if necessary by temporary local reintroduction of population testing or lockdown. Leading public health experts have recommended that this should be tried in a demonstration project in which a medium-sized city introduces weekly testing and lifts lockdown completely. The idea was not considered by the groups whose predictions have guided UK policy, so we have examined the statistical case for such a study. The combination of regular testing with strict household quarantine, which was not analysed in their models, has remarkable power to reduce transmission to the community from other household members as well as providing earlier diagnosis and facilitating rapid contact tracing.

scholarly journals Estimating the proportion of asymptomatic COVID-19 cases in an Italian region with intermediate incidence during the first pandemic wave: an observational retrospective study

2021 ◽  
Author(s):  
Domenico Martinelli ◽  
Francesca Fortunato ◽  
Sara Mazzilli ◽  
Lucia Bisceglia ◽  
Pier Luigi Lopalco ◽  
...  
Keyword(s):  
Public Health ◽  
Clinical Signs ◽  
Virus Transmission ◽  
Contact Tracing ◽  
The Public ◽  
Health Community ◽  
Important Challenge ◽  
Asymptomatic Infections ◽  
Public Health Strategies

Abstract Early in the COVID-19 pandemic, asymptomatic transmission represented an important challenge for controlling the spread of SARS-CoV-2 through the traditional public health strategies. Further understanding of the contribution of asymptomatic infections to SARS-CoV-2 transmission has been of crucial importance for pandemic control. We conducted a retrospective epidemiological study to characterize asymptomatic COVID-19 cases occurred in the Apulia region, Italy, during the first epidemic wave of COVID-19 outbreak (February 29 - July 7, 2020). We analyzed data collected in a regional platform developed to manage surveillance activities, namely investigation and follow-up of cases and contacts, contact tracing, laboratory and clinical data collection. We included all asymptomatic cases that were laboratory-confirmed during the appropriate follow-up, defined as persons infected with SARS-CoV-2 who did not develop symptoms/clinical signs of the disease. Between February 29 and July 7, 2020, a total of 4,536 cases were diagnosed with COVID-19 among 193,757 tests performed. The group of persons with asymptomatic SARS-CoV-2 infection consisted of 903 cases; the asymptomatic proportion was 19.9% (95%CI: 18.8-21.1%); this decreased with increasing age (OR: 0.89, 95%CI: 0.83-0.96; p=0.001), in individuals with underlying comorbidities (OR: 0.55, 95%CI: 0.41-0.73; p<0.001), and in males (OR: 0.69, 95%CI: 0.54-0.87; p=0.002). The median asymptomatic SARS-CoV-2 RNA positive period was 19 days (IQR: 14-31) and the cumulative proportion of persons with resolution of infection 14 days after the first positive PCR test was 74%. As the public health community is debating the question of whether asymptomatic and late spreaders could sustain virus transmission in the communities, such cases present unique opportunities to gain insight into SARS-CoV-2 adaptation to human host. This has important implications for future COVID-19 surveillance and prevention.

scholarly journals Epidemiology of COVID-19 and effect of public health interventions, Chennai, India, March - October 2020

2021 ◽  
Author(s):  
M Jagadeesan ◽  
Parasuraman Ganeshkumar ◽  
Prabhdeep Kaur ◽  
Hemalatha Masanam Sriramulu ◽  
Manikandanesan Sakthivel ◽  
...  
Keyword(s):  
Public Health ◽  
Case Fatality ◽  
Contact Tracing ◽  
Severe Illness ◽  
List Type ◽  
Rt Pcr ◽  
Case Fatality Ratio ◽  
Metropolitan City ◽  
Lessons Learnt ◽  
Public Health Strategies

AbstractObjectivesTo describe the public health strategies and their effect in controlling the COVID-19 pandemic from March to October 2020 in Chennai, India.SettingChennai, a densely populated metropolitan city in Southern India, was one of the five cities which contributed to more than half of the COVID-19 cases in India.ParticipantsWe collected the de-identified line list of all the 192,450 COVID-19 case-patients reported from 17 March to 31 October 2020 in Chennai and their contacts for the analysis. We defined a COVID-19 case-patient based on the RT-PCR positive test in one of the Government approved labs.Outcome measuresThe primary outcomes of interest were incidence of COVID-19 per million population, case fatality ratio, deaths per million and the effective reproduction number (Rt). We also analysed the indicators for surveillance, testing, contact tracing and isolation.ResultsOf the 192,450 RT-PCR confirmed COVID-19 case-patients reported in Chennai from 17 March-31 October 2020, 114,889 (60%) were males. The highest incidence was 41,064 per million population among the 61-80 years. The incidence peaked during June 2020 at 5239 per million and declined to 3,627 per million in October 2020. The city reported 3,543 deaths, with a case fatality ratio (CFR) of 1.8% and the crude death rate was 431 per million. When lockdown began, Rt was high (4.2) in March and fluctuated from April to June 2020. The Rt dropped below one by the first week of July and remained so until October 2020, even with the relaxation of restrictionsConclusionThe combination of public health strategies controlled the COVID-19 epidemic in a large, densely populated city in India. We recommend continuing the interventions to prevent resurgence, even as vaccination is being rolled out.StrengthsWe did a comprehensive analysis of COVID-19 strategies and outcome in a large, densely populated metropolitan city in India.We documented that the community-centric public health strategies were feasible and effective in controlling the COVID-19 outbreak even in a large, thickly populated cityThe lessons learnt are relevant to similar settings in low-and middle-income countries. Given the ongoing multiple waves of COVID-19 and the difficulty in controlling the transmission, our experience and lessons learnt will be valuable for policymakers and scientific advisors globallyLimitationsWe analysed the data available from the GCC database and not from the hospitals where patients with moderate to severe illness were admitted. Hence, we could not report the severity of illness among admitted patients.Second, the COVID-19 incidence might have been underestimated while testing was low during the early phase of the epidemic

scholarly journals Health Policy Issue Brief: COVID-19 in Mexico, an imperative to test, trace, and isolate.

2020 ◽  
Author(s):  
Daniel Bernal-Serrano ◽  
Hector Carrasco ◽  
Lindsay Palazuelos ◽  
Joel M. Mubiligi ◽  
Catherine Oswald ◽  
...  
Keyword(s):  
Public Health ◽  
Mass Communication ◽  
Respiratory Infections ◽  
Current Trend ◽  
Policy Issue ◽  
Contact Tracing ◽  
Public Health Approach ◽  
Health Strategy ◽  
The Government ◽  
The Impact

The Mexican government’sapproach to COVID-19 is failing. The strategy—to care for those that require hospitalization (20% of all cases), deliver mass communication messages, and regulate social distancing following a stoplight system for the rest of the population-is not aggressive enough for prevention. An anemic public health approach with scarce testing and no contact tracing or quarantine, has led to a sky-rocketing number of new infections and deaths. If the current trend continues, Mexico will see around 130 thousand deaths by December and a 53% annualized rate of decrease in the GDP. The government must implement a clear federal strategy to stop the spread of the virus: widespread testing, isolation of symptomatic cases; tracing, and quarantiningof their contacts. This comprehensive public health strategy with targeted social support to protect the vulnerable is a proven approach. Through evaluating other countries’ programs and extrapolating lessons for the Mexican context, we demonstrate thatimplementing testing and contact tracing for all acute respiratory infections is feasible with Mexico’s current resources. A strategy where symptomatic patients are tested and isolated and contacts are quarantined, can suppress community spread, save lives, reduce suffering, decrease the burden on hospitals, and restart the economic activity earlier and in a safer way. The more we wait to implement comprehensive testing and tracing to suppress the epidemic, the more people will become infected, and the impact of this measures will decrease.

scholarly journals Containing SARS-CoV-2 in Belize

2020 ◽  
Author(s):  
Kyle Habet ◽  
Diomne Habet ◽  
Gliselle Marin
Keyword(s):  
Public Health ◽  
Early Intervention ◽  
Population Density ◽  
Central America ◽  
National Level ◽  
Contact Tracing ◽  
Limited Resources ◽  
Global Pandemic ◽  
Caribbean Country ◽  
Community Transmission

Belize is a small Caribbean country in Central America with limited resources in public health. Amidst a global pandemic, urgent attention was given to mitigating the spread of SARS-CoV-2 (COVID-19) in order to prevent a public health catastrophe. Early intervention on a national level was key to preventing the importation of cases and subsequent community transmission. Limiting the conglomeration of people, implementation of curfews, closures of school and universities, government-mandated social distancing, and extensive contact tracing may have mitigated the exponential spread of COVID-19. Mandatory mask-wearing in public may have helped to prevent spread between asymptomatic carriers to susceptible individuals. A low population density may have also contributed to containing the virus.

scholarly journals Identifying Synergistic Interventions to Address COVID-19 Using a Large Scale Agent-Based Model

2020 ◽  
Author(s):  
Junjiang Li ◽  
Philippe J. Giabbanelli
Keyword(s):  
Public Health ◽  
Large Scale ◽  
Contact Tracing ◽  
Remote Work ◽  
Agent Based Model ◽  
Agent Based ◽  
Global Pandemic ◽  
Small Set ◽  
Factorial Design Of Experiments ◽  
The Individual

AbstractThere is a range of public health tools and interventions to address the global pandemic of COVID-19. Although it is essential for public health efforts to comprehensively identify which interventions have the largest impact on preventing new cases, most of the modeling studies that support such decision-making efforts have only considered a very small set of interventions. In addition, previous studies predominantly considered interventions as independent or examined a single scenario in which every possible intervention was applied. Reality has been more nuanced, as a subset of all possible interventions may be in effect for a given time period, in a given place. In this paper, we use cloud-based simulations and a previously published Agent-Based Model of COVID-19 (Covasim) to measure the individual and interacting contribution of interventions on reducing new infections in the US over 6 months. Simulated interventions include face masks, working remotely, stay-at-home orders, testing, contact tracing, and quarantining. Through a factorial design of experiments, we find that mask wearing together with transitioning to remote work/schooling has the largest impact. Having sufficient capacity to immediately and effectively perform contact tracing has a smaller contribution, primarily via interacting effects.

scholarly journals Intrinsic and realized generation intervals in infectious-disease transmission

2015 ◽  
Vol 282 (1821) ◽  
pp. 20152026 ◽  
Author(s):  
David Champredon ◽  
Jonathan Dushoff
Keyword(s):  
Public Health ◽  
Mathematical Models ◽  
Disease Transmission ◽  
Interval Data ◽  
Contact Tracing ◽  
Reproductive Number ◽  
Infectious Disease Transmission ◽  
Generation Interval ◽  
Public Health Strategies ◽  
The Relationship

The generation interval is the interval between the time when an individual is infected by an infector and the time when this infector was infected. Its distribution underpins estimates of the reproductive number and hence informs public health strategies. Empirical generation-interval distributions are often derived from contact-tracing data. But linking observed generation intervals to the underlying generation interval required for modelling purposes is surprisingly not straightforward, and misspecifications can lead to incorrect estimates of the reproductive number, with the potential to misguide interventions to stop or slow an epidemic. Here, we clarify the theoretical framework for three conceptually different generation-interval distributions: the ‘intrinsic’ one typically used in mathematical models and the ‘forward’ and ‘backward’ ones typically observed from contact-tracing data, looking, respectively, forward or backward in time. We explain how the relationship between these distributions changes as an epidemic progresses and discuss how empirical generation-interval data can be used to correctly inform mathematical models.

A Critical Analysis of Legal and Policy Responses to the COVID-19 Pandemic and its Long-term Impacts in Taiwan

2021 ◽  
Vol SI ◽  
pp. 3-10
Author(s):  
Hsing-Hao Wu ◽  
Chih-Wei Chen
Keyword(s):  
Public Health ◽  
Early Stage ◽  
Mainland China ◽  
Legal Framework ◽  
Contact Tracing ◽  
Chinese Government ◽  
Governance System ◽  
Personal Protection Equipment ◽  
Global Pandemic

The COVID-19 pandemic has dramatically impacted public health and economic and social stability worldwide since the WHO’s Public Health Emergency of International Concerns declaration in early March 2020. The COVID-19 virus was first discovered in December 2019 in Wuhan city, China, and eventually resulted in the global pandemic, of which the cumulative cases have reached 181,367,824 at the time of writing. Taiwan encountered severe public health threats because of the frequent travelers as many as 10 million who commuted annually between mainland China and Taiwan. Recognizing the imminent threats arising from an intensive flow of people from mainland China due to the lockdown policy adopted by the Chinese government, Taiwan has adopted strict border control, sophisticated contact tracing and monitoring measures, and most importantly the securing of sufficient Personal Protection Equipment supply for citizens to prevent community spread. Taiwan’s quick and precise COVID-19 response at the early stage of containing the virus has been proven very successful since the outbreak of the COVID-19 global pandemic in late February 2020. Taiwan is now struggling to fight the recent outbreak for lacking sufficient vaccines and testing capacities and shall learn from other country’s experience for countermeasures against a massive epidemic. This article aims to explore the key elements for the early success of containing the COVID-19 virus, including the comprehensive legal framework for preventing infectious disease, highly trained public health officials and governance system, and citizen self-awareness. The article then discusses the potential legal controversies and their long-term impacts on Taiwan. Finally, this article provides the concluding observation and suggestions for fighting massive infectious diseases.

SARS-CoV-2 Biochemistry, Transmission, Clinical Manifestations, and Prevention

2020 ◽  
Vol 10 (4) ◽  
pp. 303-311
Author(s):  
Gundu H. R. Rao
Keyword(s):  
Public Health ◽  
Clinical Symptoms ◽  
Clinical Manifestations ◽  
World Health ◽  
Contact Tracing ◽  
The Novel ◽  
The Us ◽  
Novel Virus ◽  
Novel Coronavirus ◽  
Health Experts

The first human case of COVID-19, caused by the novel coronavirus, was reported by health officials in the city of Wuhan, China, in December of 2019. The virus was identified as a novel coronavirus in early January 2020, and its genetic sequence was shared publicly on January 11, 2020. The novel virus, previously called 2019-novel coronavirus (2019-nCoV), is currently designated as the severe respiratory syndrome coronavirus-2 (SARS-CoV-2). On January 23, Wuhan was locked down, and the World Health Organization (WHO) declared a “public health emergency of international concern.” The viral genome of SARS-CoV-2 is around 29.8 kilobase, containing six major open reading frames. The most common clinical symptoms were fever, cough, fatigue, shortness of breath, dyspnea, muscle ache, headache, chest pain, vomiting, sore throat, and sputum production. The main mode of transmission is through respiratory particles. The incubation period is 3 to 7 days. Both asymptomatic and symptomatic patients seem to be infectious. Spike (S) proteins of SARS-CoV-2 seem to have a 10- to 20-fold higher affinity to the human angiotensin enzyme 2 (ACE2) receptor than that of SARS-CoV. The high affinity of S protein to theACE2 receptor, and the additional advantages offered by the transfection facilitators Furin and Neutropilin-1, likely, contributes to the rapid spreading of this novel virus. Since these receptors are highly expressed on a variety of cells, including vascular endothelial cells and adipose tissue, individuals with compromised function of these tissues drive greater infection and severity in patients with COVID-19. Global health experts estimate that one in five individuals worldwide could be at risk for severe COVID-19, due to underlying health conditions. There is a great need for a rapid, specific, cost-effective test for monitoring the infected individuals. Even though a 15- minute, antigen test was made available by Abbott recently, it seems that the schools, colleges, and business establishments lack the ability to use these tests effectively to keep their businesses open safely. Management of the infected individuals seems to be based on clinical symptoms that manifest as the disease progresses. The US Food & Drug Administration (FDA), has created a special emergency program for possible therapies, the Coronavirus Treatment Acceleration Program (CTAP). The program uses every available method to move new and emerging treatments as quickly as possible, keeping in mind the safety and efficacy of such therapies. According to the WHO report, there are currently more than 150 COVID-19 vaccine candidates under development. Several vaccines are in Phase 3 clinical trials. In an unprecedented effort, one of the experimental monoclonal antibody cocktails of Regeneron was used for therapeutic purposes when the US president was tested positive for COVID-19. There are no drugs or other therapeutics approved by the US FDA to prevent or treat COVID-19. The National Institutes of Health (NIH) have published interim guidelines for the medical management of COVID-19. In the absence of a cure, the only choice we all have is to follow the best practices recommended by the public health experts—use of face masks (coverings), frequent hand washing with soap, contact tracing of infected individuals, and quarantining COVID-19 positive individuals, till they are free of the highly infectious virus.

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