Serum Levels of 25-Hydroxy Vitamin D in Patients With Moderate and Severe Erectile Dysfunction

Background. Besides the extensive regulatory role in growing number of biologic processes, vitamin D has been recently considered essential for lungs function as well as protective against exacerbation of chronic obstructive pulmonary diseases. We assessed the correlation between vitamin D serum levels with pulmonary function in healthy individuals. Methods. In a cross-sectional study, healthy volunteer (n=92) participants underwent the following laboratory procedures: a blood test, a 24-hour urine collection test, and the serum level of 25-hydroxy vitamin D before undergoing spirometry. Linear correlation coefficient was calculated to detect the association between serum level of 25-hydroxy vitamin D and pulmonary volumes. Results. The mean age of participants was 39.95±9.98 years. 48% of participants showed different levels of 25-hydroxy vitamin D deficiency. We recognized a consistent direct positive correlation between serum levels of 25-hydroxy vitamin D and lung function volumes. The coefficient for forced vital capacity, forced expiratory volume in 1 second, forced expiratory flow 25–75%, and forced expiratory volume in 1 second/forced vital capacity ratio were 0.610, 0.509, 0.454, and 0.551, respectively. Conclusions. Our findings suggest correlation between higher serum levels of 25-hydroxy vitamin D and improved pulmonary function. Accordingly, supplemental vitamin D might significantly improve treatment response.

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Cholecalciferol or Calcifediol in the Management of Vitamin D Deficiency

Nutrients ◽

10.3390/nu12061617 ◽

2020 ◽

Vol 12 (6) ◽

pp. 1617 ◽

Cited By ~ 1

Author(s):

Manuel Sosa Henríquez ◽

M. Jesús Gómez de Tejada Romero

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Musculoskeletal Diseases ◽

Scientific Evidence ◽

Serum Levels ◽

Vitamin D Supplementation ◽

Negative Consequences ◽

Skeletal Health ◽

Comparative Review ◽

25 Hydroxy Vitamin D

Vitamin D deficiency is a global health problem due to its high prevalence and its negative consequences on musculoskeletal and extra-skeletal health. In our comparative review of the two exogenous vitamin D supplementation options most used in our care setting, we found that cholecalciferol has more scientific evidence with positive results than calcifediol in musculoskeletal diseases and that it is the form of vitamin D of choice in the most accepted and internationally recognized clinical guidelines on the management of osteoporosis. Cholecalciferol, unlike calcifediol, guarantees an exact dosage in IU (International Units) of vitamin D and has pharmacokinetic properties that allow either daily or even weekly, fortnightly, or monthly administration in its equivalent doses, which can facilitate adherence to treatment. Regardless of the pattern of administration, cholecalciferol may be more likely to achieve serum levels of 25(OH)D (25-hydroxy-vitamin D) of 30–50 ng/mL, an interval considered optimal for maximum benefit at the lowest risk. In summary, the form of vitamin D of choice for exogenous supplementation should be cholecalciferol, with calcifediol reserved for patients with liver failure or severe intestinal malabsorption syndromes.

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Evaluation of Serum Level of Vitamin D in Patients with Female Pattern Hair Loss Thesis

Journal of Advances in Medicine and Medical Research ◽

10.9734/jammr/2021/v33i1931091 ◽

2021 ◽

pp. 157-162

Author(s):

Manar Elsayed Taha Sadoma ◽

Ghada Fawzy Rezk Hassan ◽

Manal Mohamed ALI Elbatsh ◽

Zeinab AbdElsamd Ibrahim

Keyword(s):

Vitamin D ◽

Serum Level ◽

Hair Loss ◽

Vitamin D3 ◽

Serum Vitamin ◽

Serum Levels ◽

Common Cause ◽

Female Pattern Hair Loss ◽

Vitamin D Levels ◽

25 Hydroxy Vitamin D

Background: Female pattern hair loss (FPHL) is the most common cause of alopecia in women, characterized by diffuse non-scarring hair loss in frontal, central, and parietal areas of the scalp. Vitamin D is a factor that has recently been considered in dealing with these patients. Objective: The aim of this work was to evaluate the serum level of 25 hydroxy vitamin D in patients with FPHL to elucidate its possible role in the pathogenesis of the disease. Methods: This study included 45 patients with female pattern hair loss; Evaluation of vitamin D level by Elisa was done for both control and patients. Results: Regarding vitamin D levels, mean ± SD. 18.0 ± 11.97. Conclusion: This study indicated the correlation between FPHL and decreased serum levels of Vitamin D3. It is recommended to evaluate serum Vitamin D3 levels as well as other hormone assays in these patients.

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The Assessment of 25-Hydroxy Vitamin D Serum Level in Asthmatic Patients: A Case-Control Study

Avicenna Journal of Medical Biochemistry ◽

10.15171/ajmb.2017.12 ◽

2017 ◽

Vol 5 (2) ◽

pp. 65-69

Author(s):

Mohammad Rasoul Sharanjani ◽

Ebrahim Nadi ◽

Maryam Vasheghani ◽

Mohammad Jafari ◽

Jalal Poorolajal

Keyword(s):

Vitamin D ◽

Serum Levels ◽

Control Group ◽

Control Groups ◽

Asthmatic Patients ◽

25 Hydroxy Vitamin D ◽

The Mean ◽

25 Oh Vitamin D ◽

And Control ◽

Control Study

Background: The prevalence of vitamin D deficiency is increasing due to changes in lifestyle and dietary habits. The aim of this study was to compare the serum levels of 25-hydroxy vitamin D between patients with bronchial asthma and the healthy control group. Patients and Methods: In this case-control study, 45 patients with asthma and 45 healthy subjects were enrolled and the level of serum 25 (OH) vitamin D was measured in both groups. In addition, a welltrained observer assessed airway reversibility, peak flowmetry and spirometry in the participants. The data were statistically analyzed using t test, one-way analysis of variance (ANOVA), and chi-square test with Stata software (version 11). Results: The mean age (±SD) of participants were 49.06 ±16.43 and 46.13 ±16.10 years in case and control groups, respectively (P=.394). The prevalence of vitamin D deficiency was high in both groups (69% in case and 65.5% in control groups). The mean (±SD) serum 25 (OH) vitamin D was 16.24 (±14.98) ng/ml in case group and 17.70 (±16.07) ng/mL in control group (P=.657). We found a positive correlation between the levels of vitamin D and the amount of FEV1 (r=0.2). Conclusions: According to the present study, the mean serum levels of vitamin D differences were not statistically significant between asthmatic patients and control group. However, the results of this study showed a positive relationship between forced expiratory volumes in first second (FEV1) and vitamin D levels

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Serum levels of 25-hydroxy vitamin D correlate with idiopathic benign paroxysmal positional vertigo

Bioscience Reports ◽

10.1042/bsr20190142 ◽

2019 ◽

Vol 39 (4) ◽

Cited By ~ 9

Author(s):

Jing Ding ◽

Lei Liu ◽

Wei-Kuan Kong ◽

Xiao-Bing Chen ◽

Xudong Liu

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Benign Paroxysmal Positional Vertigo ◽

Serum Levels ◽

Chinese Patients ◽

Control Group ◽

Binary Logistic Regression Analysis ◽

Positional Vertigo ◽

25 Hydroxy Vitamin D ◽

Paroxysmal Positional Vertigo

Abstract Background: The present study aimed to evaluate serum 25-hydroxy vitamin D (25(OH) D) levels in Chinese patients with idiopathic benign paroxysmal positional vertigo (BPPV) and to investigate the possible relationship between the occurrence and recurrence of idiopathic BPPV and low 25(OH) D levels. Methods: Between 1 January 2017 and 31 May, 2018, consecutively older patients (age, older than 50 years) with idiopathic BPPV were recruited in the present study. For each patient, 2:1 sex and age matched healthy people were assigned as the control group. The influence of 25(OH) D levels on BPPV and recurrent BPPV were performed by binary logistic regression analysis. Results: In the present study, 174 patients with BPPV and 348 controls were included. The serum levels of 25(OH) D in those patients were lower than in those controls (P<0.001). One hundred eight patients were found to have vitamin D deficiency; thus, the prevalence was 62.1%, which was higher than that in the controls (42.8%). The data showed that patients with recurrent BPPV (N = 31) had lower serum levels of 25(OH) D compared with those who were not (11.2 ng/ml [interquartile range, 7.2–20.8 ng/ml] vs 18.7 ng/ml [14.2–24.8 ng/ml]). The regression analyses demonstrated that vitamin D deficiency was associated with BPPV and recurrent BPPV with an odds ratio of 2.15 (95% confidence interval [CI], 1.30–4.32; P=0.006) and 5.16 (95% CI, 1.00–34.12; P=0.05). Conclusion: Decreased serum levels of 25(OH)D were associated with the occurrence and recurrence of BPPV in a Chinese population, independent of other baseline markers.

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Are Vitamin D Levels Associated With Risk of Deep Neck Infection?

Ear Nose & Throat Journal ◽

10.1177/0145561319865498 ◽

2019 ◽

pp. 014556131986549

Author(s):

Mustafa Sıtkı Gozeler ◽

Muhammed Sedat Sakat ◽

Korhan Kilic ◽

Abdulkadir Sahin ◽

Arzu Tatar ◽

...

Keyword(s):

Vitamin D ◽

Immune System ◽

Vitamin D Deficiency ◽

Serum Levels ◽

Control Group ◽

Deep Neck Infection ◽

Neck Infection ◽

Vitamin D Receptors ◽

Vitamin D Levels ◽

25 Hydroxy Vitamin D

Deep neck infection (DNI) refers to infections in spaces created by superficial and deep cervical fascia around the muscles and organs in the neck. Vitamin D is highly important for an effective immune system. Vitamin D receptors (VDR) have been identified in immune system cells, and particularly in T and B lymphocytes, macrophages, and dendritic cells. Vitamin D deficiency is thought to result in impaired immune response, decreased leukocyte chemotaxis, and an increased disposition to infection. The purpose of this study was to investigate whether vitamin D deficiency is an underlying occult factor in the development of DNI. Sixty-five patients aged 6 to 90, diagnosed with DNI, and 70 healthy age- and sex-compatible cases were included in the study. Serum levels of calcium, phosphorus, parathyroid hormone, and 25-hydroxy vitamin D (25(OH)D) were determined in each case. 25-hydroxy vitamin D levels above 20 ng/mL were regarded as normal, 12 to 20 ng/mL as insufficient, 5 to 12 ng/mL as deficient, and less than 5 ng/mL as severely deficient. Mean serum 25(OH)D levels were 10.4 (6.2) ng/mL in the patient group and 15.5 (6.4) ng/mL in the control group ( P < .01). This difference was statistically significant ( P < .01). Vitamin D was within normal limits in 9.2% (n = 6) of cases in the study group, insufficient in 29.2% (n = 19), deficient in 35.3% (n = 23), and severely deficient in 26.2% (n = 17). The equivalent values in the control group were 21.4% (n = 15), 48.5% (n = 34), 30% (n = 21), and 0% (n = 0). Serum 25(OH)D levels were significantly lower in patients with DNI compared to the healthy cases; 25(OH)D levels may be a factor in the development of DNI.

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