Clinical Profile and Laboratory Finding of DFU From Tertiary Hospitals in Bali

Author(s):  
2021 ◽  
Vol 39 (3) ◽  
pp. 154-159
Author(s):  
Mahbuba Sultana ◽  
Sayla Chowdhury ◽  
Abdullah Al Amin

Background: Since the first detection on 8th March 2020 in Bangladesh, the number of cases is rising alarmingly. The paediatric population is also getting infected in Bangladesh. So far there is no study of COVID in children in this country. Aim: This study reports on clinical profile, laboratory findings and outcomes of COVID-19 children admitted to Combined Military Hospital (CMH), Dhaka. Materials and Methods: In this prospective observational study, RT-PCR confirmed fifty COVID-19 patients aged below twelve years were included. Relevant investigations were done in the Armed Forces Institute of Pathology (AFIP). Data were collected from patients and/or their attendants by a structured questionnaire. Results: Mean age was 59.96±43.24 months, 48% were male and 52% were female. Predominant symptoms were fever (44%), cough (26%), anosmia (26%) and diarrhea (12%). There was neutropenia in 66% and lymphocytosis in 84% of cases. Mean neutrophil and lymphocyte counts were 38±13% and 52.5±13%, respectively. Significantly raised CRP observed in 14% and high serum procalcitonin was in10% of cases. Serum LDH, D-Dimer and ferritin were raised in 80%,34% and 6% of affected children, respectively. The majority (98%) of the children were improved and discharged from the hospital. One child died in this cohort. Conclusion: Fever and cough were the predominant symptoms of COVID-19 affected children in this study. Lymphocytosis and neutropenia were two important laboratory finding. Death in COVID-19 is also not uncommon. J Bangladesh Coll Phys Surg 2021; 39(3): 154-159


2015 ◽  
Vol 33 (2) ◽  
pp. 261-268 ◽  
Author(s):  
Y. Xu ◽  
J. Bai ◽  
G. Wang ◽  
S. Zhong ◽  
X. Su ◽  
...  

2021 ◽  
Vol 12 (4) ◽  
pp. 54-60
Author(s):  
Reena Anie Jose ◽  
Hyma Jose ◽  
Anjali Anne Jacob ◽  
Pramod Thomas ◽  
Renu Mathew ◽  
...  

Background: Scrub typhus (ST) is a common Rickettsial infection which has been increasingly reported from the various states of southern part of India. Aims and Objective: With very few reports from Central Kerala, we aimed to study the seroprevalence of scrub typhus and its clinical profile. Materials and Methods: Patients presenting with acute undifferentiated febrile illness and other symptoms and signs of Rickettsial infections during a period of two years were included in this prospective study. Serodiagnosis of ST was based on a positive Scrub typhus IgM Enzyme Linked Immunosorbent Assay (ELISA) and/or agglutination for OXK in Weil Felix test. The cut-off for ELISA was calculated. The clinical and laboratory details of the positive patients were obtained and bivariate analysis was performed. Results: The cut-off for ST IgM ELISA was calculated and found to be 0.38. Of the 636 samples screened, 34 (5.3%) were positive for ST IgM ELISA. Out of the 34 positive samples, only 5 (0.8%) were positive by Weil Felix test. Most of the ST patients presented during the months of May to January. Rashes were observed in 8.8% of the ST patients and none had signs of eschar. The commonest clinical features included fever, myalgia (52.9%), nausea & vomiting (32.4%), headache (29.4%) and hepatosplenomegaly (29.4%). The commonest abnormal laboratory finding and complication observed were elevated serum transaminases (52.9%) and acute respiratory distress syndrome (17.6%) respectively. Conclusion: The seroprevalence of ST in Central Kerala was 5.3% using Weil Felix test and ST IgM ELISA.


Author(s):  
I Nyoman Semadi ◽  
Kelvin Setiawan ◽  
Hendry Irawan

Introduction: Diabetic foot ulcer (DFU), as one of the chronic non-healing wounds, causes a significant financial burden on the healthcare system worldwide. Chronic wounds usually exhibit powerful pro-inflammatory stimuli, as seen in laboratory results. Aim: For this reason, we conducted an observational study to obtain the clinical profile, hematological profile, and biochemical profile from our DFU patient laboratory examinations. Material and methods: This study was a retrospective descriptive study conducted between March 2016 and December 2018 in Sanglah Hospital, Bali which included a total of 113 patients. The variables included in this study consisted of DFU clinical status, treatment procedures, and laboratory results. We further divided the laboratory results into two groups, haematological and blood chemistry profile. All numerical data were summarized as mean ± standard deviation, and categorical variables were summarized as frequency and percentage. Results and discussion: The mean patient’s age was 55.68 ± 10.52 years old. The most of patients were male (54.9%). Leukocytosis was observed in these patients (13.80 ± 6.48 × 109/L) and neutrophil dominated the white blood differential count. There were 35 patients (30.97%) with creatinine levels above 1.3 mg/dL, 73 patients (64.6%) with random blood glucose above 180 mg/dL, and 78 patients (67.3%) with HbA1c levels higher than 53 mmol/mol, even 33 patients (29.2%) with HbA1c more than 86 mmol/mol. Conclusions: Some laboratory values have a significant meaning in diabetic foot patients, which can become instruments for the physician in diagnosing, select the most effective treatment, and predict outcome or complications in DFU patients.


2007 ◽  
Author(s):  
Emilie Chan ◽  
Ewelina Zaremba ◽  
Jacques Bradwejn ◽  
Diana Koszycki

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