scholarly journals A reasonable Response to Diphensiprone in Pediatric Alopecia Patient: A Case Report

2021 ◽  
Vol 2 (1) ◽  
pp. 01-03
Author(s):  
Selma Bakar DERTLİOĞLU

Alopecia areata (AA) is an autoimmune disorder which accounts for the most frequent cause of inflammation based hair loss among dermatological outpatient attendances. It has an unpredictable course and its etiology has not yet been fully elucidated. Many alternatives treatments are available; however, none of them have been curative or preventive so far. Its treatment must be individualized, and aims at suppressing the phase of activity of the disease. Alopecia areata (AA) persistent for a minimum of 6 months and resistant to other treatments and/or severe AA are indications to use diphencyprone (DPCP). We report a 9 year-old boy with diffuse alopecia areata, who underwent topical immunotherapy with diphencyprone. The application procedures, the results obtained and the clinical follow-up are described. Treatment alternatives should be tried, especially in the pediatric age group, due to the prominent effects of the disease on the patient’s quality of life and consequent development of psychological impairments. In this case; DPCP application is a preferable treatment option in AA in the pediatric age group because is very easy, effective and with less side effects

2012 ◽  
Vol 2 (1) ◽  
pp. 12 ◽  
Author(s):  
Tomoaki Kimura ◽  
Kiyoshi Suzuki ◽  
Seiya Uchida ◽  
Hiroshi Katamura

Shorter and easier methods of conducting community health surveys would be useful. We conducted a study to demonstrate the responsiveness of the 10-item Mokichi Okada Association quality of life questionnaire (MQL-10) in a follow-up survey and to determine the minimally important difference (MID) for this measure. In 2007, Japanese adults participated in a survey on health prac- tices. We analyzed the MQL-10 scores (n=6365) together with the following factors: gender, age group, disease, reason for participation, and complementary health practices, such as food and eating. The mean baseline MQL-10 score was 26.4±5.83 [standard deviation (SD)] and the mean follow-up score was 27.6±5.45 SD with a mean change of 1.20±4.41 SD. The effect size for change was 0.21 and the standardized response mean was 0.27. The MQL-10 scores in the baseline condition were associated with gender, age group, disease, reason for participation and complementary health practices. Furthermore, the changes in the MQL-10 during the 12 weeks of study were associated with age group, disease, reason for participa- tion and complementary health practices. The increase in frequency of health practices was significantly associated with improvements in the participants’ quality of life (QOL). These results suggest that the MQL-10 is use- ful for assessing the effects of complementary health practices on QOL. The estimate of 3 points for the range of this measure (0-40) was higher than half of the SD of scores; therefore, it was considered reasonable for the MID.


2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Dora H. AlHarkan ◽  
Eman S. Kahtani ◽  
Priscilla W. Gikandi ◽  
Ahmed M. Abu El-Asrar

Purpose.To identify and study causes of vitreous hemorrhage (VH) in pediatric age group and to investigate factors predicting visual and anatomical outcomes.Procedure.A retrospective review of patients aged 16 years or less with the diagnosis of vitreous hemorrhage from January 2005 until December 2010.Results.A total number of 230 patients (240 eyes) were identified. Traumatic vitreous hemorrhage accounted for 82.5%. In cases of accidental trauma, final visual acuity of 20/200 was significantly associated with visual acuity of ≥20/200 at presentation and the absence of retinal detachment at last follow-up. Patients with nontraumatic vitreous hemorrhage were significantly younger with higher rates of enucleation/evisceration/exenteration and retinal detachment at last follow-up compared to traumatic cases.Conclusion.Trauma is the most common cause of VH in pediatric age group. In this group, initial visual acuity was the most important predictor for visual outcome, and the presence of retinal detachment is a negative predictor for final good visual outcome. The outcome is significantly worse in nontraumatic cases compared to traumatic cases.


2020 ◽  
Vol 7 (6) ◽  
pp. 1218
Author(s):  
Natasha L. Vageriya ◽  
Shivaji B. Mane ◽  
Taha Daginawala ◽  
Himangi Athawhale ◽  
Hussain Kotawala ◽  
...  

Background: Objective of this study is to explore various ureteric substitutes in pediatric age group and their outcomes.Methods: Retrospective analysis was done from 2003-2016, of all patients operated in this hospital that had undergone ureteral replacement. Thirteen such patients (5 from initially published paper (1) and 8 new patients) were followed up to find conduit patency, renal function and related complications with their outcomes assessed.Results: Ureteric substitution was done in 8 patients. Age of the patient ranged from 4 months to 8 years. Out of these for 2 patients monti tube was created; one with colon and other jejunum, rest of the 6 patient appendix was used. On follow up one patient had early appendico-ureteral leak requiring re-anastomosis and one patient had partial obstruction at 6 months corrected by dividing mesentry and untwisting appendix. With a mean follow up of 3.8 years all patients have preserved renal functions and drainage present. Also 5 patients of ureteral substitution performed at this institution and published prior were followed up with mean follow up of 10.4 years having no complaints with preserved function and unobstructed drainage.Conclusions: This small series supports that not only appendix and ileum but even colon as well as jejunum should be considered as Monti’s tube for ureteric replacement, when confronting with short ureter in paediatric age group.


Author(s):  
Arshed Ali ◽  
Jasif Nisar ◽  
Ihsan Ali ◽  
Rauf Ahmad

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">This prospective study was conducted in our department with the objective to study the quality of life outcome after adenotonsillectomy in children with sleep disorderd breathing. Sleep-disordered breathing, can lead to substantial morbidities, affecting the central nervous system (CNS), the cardiovascular and metabolic systems, and somatic growth, ultimately leading to reduced quality of life. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">This prospective study was conducted in 47 patients in the Department of Otorhinolaryngology Head and Neck Surgery, Government Medical College and associated SMHS Hospital Srinagar. The study was included the patients with SDB in pediatric age group, who visited in our OPD.OSA-18 questionnaire was used pre-operatively, at 2 and 6 months after surgery.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Our study groups comprised of total 47 patients with majority of patients with in age group of 5-7 years, males were 29 (61.70%) and females were 18 (38.30%). In our study the OSA 18 scale used pre-operatively showed majority of patients 33 (70.21%) having score &gt;80 score, with mean OSA-18 score of 84.15 showing that there was a major impact on quality of life and there was significant improvement in mean OSA-18 score in postoperative period from 30.49 to 26.85 at 2 and 6 months post- operatively and hence improvement in quality of life. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Based on the observation made in the study we concluded that there was a significant improvement in the disease specific postoperative quality of life after both adenotonsillectomy and tonsillectomy. We also concluded that polysomnography results matched with OSA 18 questionnaire scale score done preoperatively.</span></p>


2017 ◽  
Vol 1 (1) ◽  
pp. 36-37
Author(s):  
Ruchi Pandey

The Agnikarma is one of the para-sugical procedures mentioned by Sushruta for the management of musculo-skeletol disorders. In geriatric age group osteoarthritis is burning problem which affects the quality of life of an individual. The treatment for OA knee joint includes analgesic, steroid injections and lastly surgery with their own limitations. The purpose of this video presentation of Agnikarma is to demonstrate this procedure to the Ayurveda practioners for the management of OA. During the Post Graduate research work author tried this procedure in 42 patients of OA knee joint. Among them 30 patients were recovered from pain and no pain was noted by those patients during follow up for 6 months. So this simple procedure can be repeated after 6 months. Patient can be free from pain and no need of abuse of analgesic so that old age patient can enjoy the quality of life. 


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Abdalla Mohmed Alasiri ◽  
Reem Abdullah Alasbali ◽  
Meaad Ali Alaqil ◽  
Aishah Marei Alahmari ◽  
Nouf Dagash Alshamrani ◽  
...  

Abstract Background Pulmonary alveolar proteinosis is a rare interstitial lung disease characterized by accumulating surfactant materials in the alveoli. The autoimmune form is by far the most common in adults, while in the pediatric age group, the vast majority of cases are congenital. We report a case of an adolescent patient diagnosed with autoimmune pulmonary alveolar proteinosis, which is unusual in this age group. Case presentation A-15 year-old Saudi male presented to the emergency department with a history of shortness of breath and low oxygen saturation. High-resolution computed tomography of his chest showed a global crazy-paving pattern. Autoantibodies against granulocyte-macrophage colony-stimulating factor were detected in his serum. A diagnosis of the autoimmune form of pulmonary alveolar proteinosis was confirmed after excluding other possible causes. The patient improved after he underwent whole lung lavage under general anesthesia, and he was independent of oxygen therapy after 6 months of follow-up. Conclusion The autoimmune form of pulmonary alveolar proteinosis is rare in the pediatric age group and should be considered when no apparent cause of this disease was found. Whole lung lavage should be the first treatment modality offered in this setting with close follow-up and monitoring.


2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 4562-4562
Author(s):  
Mette Sprauten ◽  
Marianne Brydoy ◽  
Hege Sagstuen Haugnes ◽  
Carl Wilhelm Langberg ◽  
Olav Dahl ◽  
...  

4562 Background: Hypogonadism, i.e., low T-, high LH- and/or FSH-levels, is frequently observed in TCSs and is associated with cardiovascular disease, osteoporosis and reduced quality of life. Little is known about the impact of aging on hypogonadism in TCSs. Methods: T, LH, and FSH levels were retrieved twice from 874 TCSs median 11 (S11) and 19 (S19) years after orchiectomy and categorized based on cut-offs calculated from 570 healthy controls (C), separately for each decadal age group. Treatment was categorized into surgery (S), radiotherapy (RT) or cisplatin-based chemotherapy (CT). Impact of treatment and aging on T, LH and FSH levels was assessed by comparing proportions of TCSs grouped into the C quartiles by ordinal logistic regression and expressed with odds ratios (OR) and 95% confidence interval (CI). Results: TCSs had lower T and higher LH and FSH levels than C at S11 and S19 (p<0.05, except for LH after S at S11) (Table).Approximately 50% of TCSs had T levels in the lowestquartile at S11 and S19. The proportion of TCSs with T below the 2.5% cut-off threshold for C increased from S11 to S19, for the S (9.7 - 12.5%), RT (9.4 - 16.3%) and CT group (12.5- 19.9%). Conclusions: TCSs had lower T and higher LH and FSH levels than C of similar age indicating an impact of treatment. Importantly, proportions of TCSs in the highest LH quartile and below the 2.5% cut-off for T-level increased from S11 to S19, indicating an accelerated hormonal aging. Continued follow-up of hormone levels is important. [Table: see text]


2017 ◽  
Vol 8 (2) ◽  
pp. 425-428 ◽  
Author(s):  
Charudutt Kalamkar ◽  
Amrita Mukherjee

Purpose: Primary corneoscleral cyst is a rare disease occurring in the pediatric age group. We report a case of corneoscleral cyst with visual diminution. Methods: We conducted a case report. Results: A 7-year-old girl presented with corneal opacity in the left eye. Examination revealed a corneoscleral cyst. The corneal part of the cyst involved visual axis. Surgical excision with a scleral graft was performed, leading to an improvement in visual acuity. No recurrences were observed until the last follow-up at 18 months. Conclusions: Corneoscleral cyst should be considered in the differential diagnosis of cystic ocular surface disorders in the pediatric age group.


1988 ◽  
Vol 102 (6) ◽  
pp. 546-548 ◽  
Author(s):  
Mufid H. Abdu ◽  
Joseph G. Feghali

Abstract Uvulopalotopharyngoplasty (UPPP) has been recently popularized for the treatment of snoring and sleep apnea syndrome (SAS). All reported cases so far have been adults and the use of this procedure in the pediatric age group has not as yet been reported. Obstructive sleep apnea in children has been classically treated previously either medically or by adeno-tonsillectomy. The case of a three year old child with obstructive sleep apnea secondary to a large uvula and a redundant soft palate is reported. The child was successfully treated by UPPP, and remained free of symptoms for a follow-up period of one year.


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