scholarly journals FREQUENCY AND RISK FACTORS AFFECTING THE BIRTH RATE OF CHILDREN WITH CONGENITAL CLEFT LIP AND PALATE IN THE SOUTHERN REGION OF KYRGYZSTAN.

ASJ. ◽  
2021 ◽  
Vol 1 (50) ◽  
pp. 10-13
Author(s):  
A. Eshiev ◽  
N. Taalaibekov ◽  
E. Derbishev
Keyword(s):  
Risk Factors ◽  
Infectious Diseases ◽  
Hard Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Maxillofacial Surgery ◽  
First Trimester ◽  
Southern Region ◽  
Comprehensive Treatment ◽  
Congenital Cleft

The aim of the study is to examine the incidence and factors of congenital cleft lip and palate in the southern region of the Kyrgyz Republic, according to the form of clefts and according to the classification of MMDI, as well as their rehabilitation. We studied in detail the case histories of 2116 patients treated in the maxillofacial surgery department of Osh Interregional United Clinical Hospital according to the age and sex, as well as the form of congenital cleft lip and palate. Moreover, a questionnaire was administered to parents of children with CCLP for risk factors during pregnancy. A retrospective study of medical history revealed, among congenital anomalies, clefts of the soft, hard palate, alveolar process and upper lip prevailed - (combined) 891 (42,3%) Congenital cleft of soft, hard palate - 586 (27,7%), then isolated congenital cleft of the maxilla - 415 (19,6%), congenital cleft of the soft palate only 10,5% - 224 children were followed. The results of the questionnaire revealed that the parents of children born with CCLP were influenced by various unfavorable factors in the period of formation of the facial section of the fetus. The survey revealed that the relatives had CCLP, which accounted for 12.9% of all newborns, indicating a rather high role of hereditary predisposition. In addition to the hereditary genetic factor, an important role is played by infectious diseases suffered during the first trimester. It is noted that 12.8% of the children born with CCLP had infectious diseases. The mothers independently took drugs during pregnancy (antibiotics, salicylates, sulfonamides without a doctor's prescription), 17.6% of women were anemic during pregnancy, and 16.3% had severe toxemia. Along with this, it was found that the smallest number of women suffered mental trauma in the first trimester of pregnancy 0.4% of the mothers of children born with CCLP. Further, we registered patients with CCLP in the special software ONYX CEPH-3 from 01.01.2015 to the present, where we enter detailed information about patients with CCLP pathology. It creates convenience for parents both informationally and economically, as well as directly for the doctor in terms of dynamic observation of the functional and aesthetic condition and development of the child. In order to further develop programs to prevent the prevalence of congenital pathology, improve the quality of comprehensive treatment method, as well as medical and social rehabilitation of such patients and work with families of children with CCLP, we have developed a single program ONYX CEPH3 providing dispensary and rehabilitation of children.

scholarly journals ALGOTITHM OF CHILDREN`S REHABILITATION WITH CLEFT LIP AND PALATE IN THE REGION WITH ECOTOXICANTS

2019 ◽  
Vol 15 (2) ◽  
pp. 89-96 ◽  
Author(s):  
Сергей Чуйкин ◽  
Sergey CHUYKIN ◽  
Наиль Давлетшин ◽  
Nail' Davletshin ◽  
Олег Чуйкин ◽  
...  
Keyword(s):  
Medical Records ◽  
Petrochemical Industry ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Maxillofacial Surgery ◽  
Additional Treatment ◽  
The Body ◽  
Blood Tests ◽  
Congenital Cleft ◽  
Somatic Diseases

Subject: development of an algorithm for the rehabilitation of children with congenital cleft lip and palate in a region with petrochemical ecotoxicants. Objectives: optimization of the algorithm for the rehabilitation of children with congenital cleft lip and palate in the region with ecotoxicants. Methods. A retrospective analysis of the medical records of children with a diagnosis of congenital cleft lip and palate was conducted on the basis of the Republican Children's Clinical Hospital in Ufa in the department of maxillofacial surgery. In the period from January 1, 1985 on December 31, 2018 were surveyed 3463 children with congenital cleft lip and palate. Results. Children born and living in the region with the petrochemical industry have a high percentage of concomitant somatic diseases and deviations from the norm in blood tests. An algorithm was developed for the rehabilitation of children with congenital cleft lip and palate in the region with petrochemical ecotoxicants, optimized by including a toxicologist, anesthesiologist, immunologist, otorhinolaryngologist, gastroenterologist, and endocrinologist in the algorithm of consultation and treatment. The algorithm is aimed at improving the health of the child by increasing the effectiveness of prevention and treatment of somatic diseases in the preoperative period. Conclusions. The proposed algorithm for the rehabilitation of children with congenital cleft lip and palate has been developed taking into account the adverse effects on the body of emissions into the air of large petrochemical enterprises. Children with congenital cleft lip and palate, born and living in a region with petrochemical ecotoxicants, have a high percentage of somatic diseases and contraindications to surgical treatment according to accepted terms due to the presence of comorbidities and disorders in blood tests, and need additional treatment from a toxicologist, anesthesiologist and other specialists.

scholarly journals ANALYSIS OF THE FREQUENCY OF BIRTH OF CHILDREN WITH CONGENITAL DEVELOPMENT DISORDERS IN A CITY WITH A PETROCHEMICAL INDUSTRY

2020 ◽  
Vol 16 (1) ◽  
pp. 139-142
Author(s):  
Sergey Chuykin ◽  
Julia Andrianova ◽  
Natal'ya Makusheva ◽  
Oleg Chuykin ◽  
Kristina Kuchuk ◽  
...  
Keyword(s):  
Petrochemical Industry ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Average Rate ◽  
Maxillofacial Surgery ◽  
Northern Region ◽  
Medical Documentation ◽  
Oral And Maxillofacial Surgery ◽  
Industrial Emissions ◽  
Congenital Cleft

Thing. Studying the frequency of birth of children with congenital malformations in a city with a petrochemical industry. The goal is to identify the effect of industrial emissions from enterprises in Ufa on the frequency of birth of children with congenital cleft lip and palate. Methodology. In the Department of Oral and Maxillofacial Surgery of the Republican Children's Clinical Hospital from 1985 to 2019, the medical documentation of children born in the city with a petrochemical industry with a cleft lip and palate was studied. Results. In industrial areas of Ufa, the average rate of birth of children with clefts is 3.65 ± 0.31 (Kalininsky) and 2.34 ± 0.29 (Ordzhonikidzevsky). According to our studies, it was found that in the industrial zone, the frequency of birth of children with congenital facial pathology is significantly higher than in environmentally safe areas, and ranges from 1: 282 (3.5) in the Kalinin industrial northern region to 1:859 (1.1) in the southernmost, ecologically safe Demsky district (p<0.01). On the whole, in Ufa, the average rates of the birth rate of children with congenital cleft lip and palate were 1:454 (2.204 ± 0.11). Conclusions. The correlation between the value of gross emissions of harmful substances into the atmospheric air and the frequency of congenital cleft lip and palate in the zone with emissions of 135,114―180,120 tons per year, then in the zone with the amount of emissions of 20,000―135,114 tons per year, and the frequency in the zone with emissions of 11,000 is less ― 20,000 tons per year. The average birth rates for children with ARVH in the cities of the Republic of Bashkortostan were per 1000 children born: in cities with NHP ― 2.44; in cities without NHP ― 1.13. The frequency of birth of children with ADV in cities with NHP is more than 2 times higher than the frequency of birth of children with ADV in cities without NHP (p <0.001).

Alveolar Bone Grafting in Patients with Complete Clefts: A Comparative Study between Secondary and Tertiary Bone Grafting

2002 ◽  
Vol 39 (1) ◽  
pp. 18-25 ◽  
Author(s):  
Rupert Dempf ◽  
Thomas Teltzrow ◽  
Franz-Josef Kramer ◽  
Jarg-Erich Hausamen
Keyword(s):  
Bone Grafting ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Alveolar Bone ◽  
Maxillofacial Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Comprehensive Treatment ◽  
Alveolar Bone Grafting ◽  
Medical University ◽  
Mixed Stage

Objective This investigation evaluated the results of alveolar bone grafting in patients with complete clefts, comparing secondary alveolar bone grafting (during the mixed stage of dentition) versus tertiary bone grafting (after completion of the second stage of dentition). Design This was a retrospective study. Of 140 osteoplasties, which all were operated according to the same standardized surgical technique, a clinical and roentgenological follow-up investigation was carried out in a collective of 85 osteoplasties. Clinically we searched for oronasal fistulae, assessed the periodontal status, determined the extent of the gingival attachment in the area of the osteoplasty, and searched for vertical growth disturbances in the area of the osteoplasty. Roentgenologically the height of the alveolar bone in the former clefted area was ascertained. Setting Records were obtained from a clinical and radiological study of the Department of Oral and Maxillofacial Surgery of the Medical University of Hannover (Germany). Interventions All patients were operated with the same standardized surgical method. The osteoplastic bridging of the alveolar cleft was performed via a vestibular gingival marginal incision and exclusively by grafting of cancellous bone from the iliac crest. Results The best results of alveolar bone grafting in cases of secondary osteoplasty were obtained when the lateral incisor or canine had grown into the transplant and had led to a functional stress of the transplanted bone. Approximately good results were to be found in tertiary osteoplasty when the transplanted bone had been stressed functionally through a dental implant. Comparing the secondary with the tertiary osteoplasty, there was a trend of lower resorption in secondary osteoplasty. Conclusions Secondary osteoplasty should represent an integral component of any concept for the comprehensive treatment of patients with cleft lip and palate.

scholarly journals SOMATIC DISEASES IN CHILDREN WITH CONGENITAL LIP AND PALATE IN A REGION WITH INDUSTRIAL PETROCHEMICAL ECOTOXICANTS

2021 ◽  
Vol 17 (2) ◽  
pp. 121-126
Author(s):  
Oleg Chuykin ◽  
Galina AKATYEVA ◽  
Natal'ya Makusheva ◽  
Kristina Kuchuk ◽  
Marsel' Gil'manov
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Maxillofacial Surgery ◽  
Congenital Cleft ◽  
Functional Features ◽  
The Moment ◽  
Systemic Pathology ◽  
Somatic Diseases ◽  
Somatic State ◽  
Primary Section

Monitoring of congenital malformations and concomitant somatic diseases in children is one of the important indicators of the causal influence of environmental factors on the health of the population. From the moment of birth, a child with congenital cleft lip and palate differs significantly from healthy peers not only externally, but also morpho-functional features of the structure of the primary section of the digestive and respiratory systems and often has a greater number of previous diseases in the history. Purpose: To determine the structure and frequency of somatic morbidity in children with congenital cleft lip and palate in regions with petrochemical ecotoxicants. Materials and methods: During the study, 3463 children from birth to 16 years old with congenital cleft lip were treated and monitored at the Department of Maxillofacial Surgery at the Republican Children's Clinical Hospital, Ufa for the period from January 1, 1985 to December 31, 2019 and / or sky. The diagnosis of concomitant systemic pathology was recorded based on the findings of the district pediatricians, ENT doctor, gastroenterologist, immunologist, allergist, rheumatologist from outpatient and inpatient records of the examined patients. Conclusion. In the course of our study, a direct relationship was noted between the level of environmental pollution by ecotoxicants and the frequency of concomitant somatic diseases in children with congenital cleft lip and palate. This must be taken into account in the pre- and postoperative algorithm for the rehabilitation of children with congenital cleft lip and palate with the involvement of pediatricians to improve the general somatic state of children when planning reconstructive surgery.

scholarly journals Fatores de Riscos na Fissura Labiopalatina Não Sindrômica

UNICIÊNCIAS ◽  
2021 ◽  
Vol 24 (1) ◽  
pp. 86-93
Author(s):  
Carla Meliso Rodrigues Silvestre ◽  
Renata Cristina Giroto Ferreira da Silva ◽  
Ageo Mario Candido da Silva ◽  
Walkiria Shimoya Bittencourt ◽  
Yolanda Benedita Abadia Martins de Barros ◽  
...  
Keyword(s):  
Risk Factors ◽  
Environmental Factors ◽  
Literature Review ◽  
Cleft Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
First Trimester ◽  
Human Beings ◽  
Factors Associated ◽  
Narrative Literature Review

As anomalias craniofaciais representam um grupo amplo de malformações congênitas que afetam uma grande proporção da sociedade mundial. Entre essas se encontram as fissuras de lábio e/ou de palato, anomalia orofacial mais frequente entre os seres humanos que ocasionam problemas estéticos e funcionais nos indivíduos afetados.  A etiologia das fissuras labiopalatinas isoladas ou não-sindrômicas é complexa e multifatorial, associadas à fatores hereditários e ambientais. Este estudo teve como objetivo relatar os fatores genéticos e ambientais associados à etiologia desse tipo de malformação, através de uma revisão narrativa de literatura, a partir das bases de dados: PubMed e Scielo. Os descritores utilizados foram: cleft palate AND cleft lip AND etiology AND risk factors. Incluíram-se artigos nos idiomas inglês e português publicados em periódicos nacionais e internacionais acerca da temática da pesquisa. Baseado na revisão de literatura se pode identificar que os fatores ambientais como: fumo, consumo de álcool, consumo de medicamentos, o não uso de suplementação com polivitamínicos e ácido fólico, exposição a agrotóxicos, idade dos genitores podem aumentar a chance de ocorrência das fissuras labiopalatinas. O acompanhamento gestacional durante o primeiro trimestre gestacional se faz necessário, a fim de monitorar os fatores de risco associados com as fissuras labiopalatinas não sindrômicas.   Palavras-chave: Fissura Palatina. Fenda Labial. Etiologia. Fatores de Risco.   Abstract Craniofacial anomalies represent a broad group of congenital malformations that affect a large proportion of world society. Among them are cleft lip and / or palate, the most frequent orofacial anomaly among human beings that cause aesthetic and functional problems in the affected individuals. The etiology of isolated or non-syndromic cleft lip and palate is complex and multifactorial, associated with hereditary and environmental factors. This study aimed to report the genetic and environmental factors associated with the etiology of this type of malformation through a narrative literature review conducted in October 2020, using the PubMed and Scielo databases. The keywords used were cleft palate AND cleft lip AND etiology AND risk factors. Articles in English and Portuguese published in national and international journals about the research theme were included. Based on the literature review, it can be identified that environmental factors such as smoking, alcohol consumption, medication consumption, the non-use of supplementation with multivitamins and folic acid, exposure to pesticides, age of parents can increase the chance of cleft lip and palate occurrence. Gestational monitoring during the first trimester of pregnancy is necessary in order to monitor the risk factors associated with non-syndromic cleft lip and palate.   Keywords: Cleft Palate. Cleft Lip. Etiology. Risk Factors.

The Prevalence and Risk Factors of Congenital Cleft Lip and Palate in the Northern Region of Saudi Arabia

2021 ◽  
Vol 8 (4) ◽  
pp. 41-50
Author(s):  
Abdullah N. Alrasheedi ◽  
Sultan Faisal Alshaalan ◽  
Hussam Ahmed Alruwaili
Keyword(s):  
Risk Factors ◽  
Saudi Arabia ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Northern Region ◽  
Congenital Cleft

scholarly journals The use of various types of autografts in the bone grafting of the alveolar process

2020 ◽  
Vol 24 (1) ◽  
pp. 69-74
Author(s):  
A. V. Makeev ◽  
O. Z. Topolnitsky ◽  
R. N. Fedotov
Keyword(s):  
Bone Grafting ◽  
Selection Criteria ◽  
Cleft Lip ◽  
Iliac Crest ◽  
Cleft Lip And Palate ◽  
Maxillofacial Surgery ◽  
Alveolar Process ◽  
Bone Material ◽  
Dental Implantation ◽  
Congenital Cleft

Relevance. Fixing a cleft alveolar process is one of the most complicated problems in pediatric maxillofacial surgery. The difficulty lies in the fact that bone grafting of the alveolar process directly affects the growth of the upper jaw, the difficulty of performing surgery, as well as trying to form a sufficient amount of bone regenerate, while it is necessary to restore the anatomical integrity of the alveolar process for subsequent orthodontic treatment or dental implantation. Purpose: To review the literature on the use of autografts from various donor areas in patients with congenital cleft upper lip, alveolar process, hard and soft palate. Materials and methods: A literature review of the data was carried out using the electronic databases “Medline”, “Pubmed”, “Kibeleninka”. The key words in the search were: bone plastic, cleft alveolar process. The selection criteria were the articles in English and Russian containing clinical studies on the use of various types of grafts in bone grafting of the alveolar process cleft. Results: The sources of literature on the use of various autografts for bone grafting of the alveolar outgrowth in children with cleft lip and palate were analyzed. Currently, most authors are inclined to use an iliac crest autograft in surgery. Conclusion: Although more than a century has passed since the first alveolar cleft bone graft surgery was performed, the choice of bone material is still unresolved - due to the severity of complications, the impossibility of taking a sufficient amount of bone material, as well as a high percentage of material resorption, because even with the use of iliac crest bone, the volume of transplant resorption can be over 40%.

scholarly journals CLINICAL AND ANATOMICAL FORMS OF CONGENITAL CLEFT LIP AND PALATE IN THE REGION WITH ECOTOXICANTS

2019 ◽  
Vol 15 (3) ◽  
pp. 127-132 ◽  
Author(s):  
Сергей Чуйкин ◽  
Sergey Chuykin ◽  
Назим Джумартов ◽  
Nazim Dzhumartov ◽  
Олег Чуйкин ◽  
...  
Keyword(s):  
Petrochemical Industry ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Maxillofacial Surgery ◽  
Industrial Area ◽  
Medical Documentation ◽  
Number Of Children ◽  
Republic Of Bashkortostan ◽  
Congenital Cleft ◽  
The Republic

Subject: the study of the features of clinical and anatomical forms of congenital cleft lip and palate in the region with the petrochemical industry. Objectives ― determination of the clinical-anatomical forms of congenital cleft lip and palate, the identification of the frequency of severe forms in the region with the petrochemical industry and in the region without industrial eco-toxicants. Methods. We have studied medical documentation in the Department of Maxillofacial Surgery of the Republican Children's Clinical Hospital for the period from January 1, 1985 to December 31, 2018 to study the structure of the clinical and anatomical forms of congenital clefts of the lips and palate in children living in the Republic of Bashkortostan. During the analyzed period, 3463 children from birth to 16 years with congenital cleft lip and palate underwent treatment and dispensary observation. Results. Our data suggest that in the area with petrochemical ecotoxicants, the percentage of severe forms of congenital cleft lip and palate is higher (77.5%) than in an area without petrochemical ecotoxicants (68.7%). Conclusions. Thus, environmental pollution by petrochemical ecotoxicants leads to an increase in the number of children with congenital cleft lip and palate. There is a relationship between the level of air pollution by gross emissions from petrochemical enterprises and the severity of the clinical-anatomical forms of congenital cleft lip and palate in children living in an industrial area. It is important and important in the prenatal prevention of congenital clefts of the lip and palate.

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