scholarly journals The effect of prepartum negative dietary cation-anion difference and serum calcium concentration on blood neutrophil function in the transition period of healthy dairy cows

2020 ◽  
Vol 103 (7) ◽  
pp. 6200-6208
Author(s):  
Rita Couto Serrenho ◽  
Emma I. Morrison ◽  
Osvaldo Bogado Pascottini ◽  
Trevor J. DeVries ◽  
Todd F. Duffield ◽  
...  
2002 ◽  
Vol 55 (4) ◽  
pp. 219-222 ◽  
Author(s):  
Naoto SUZUKI ◽  
Akihiro DAIRAKU ◽  
Tomio KATAGAI ◽  
Gensei TSUNODA ◽  
Kazuyuki SUZUKI ◽  
...  

2014 ◽  
Vol 59 (No. 3) ◽  
pp. 128-133
Author(s):  
E.G. Salgado-Hernández ◽  
A. Aparicio-Cecilio ◽  
F.H. Velásquez-Forero ◽  
D.A. Castillo-Mata

Parturient paresis and subclinical hypocalcemia are frequent metabolic disorders in dairy cows postpartum. The aim of this study was to determine the effect of postpartum partial milking in the first two milkings on blood serum calcium concentration in dairy cows. Twenty multiparous Holstein dairy cows were randomized into two groups. Cows of group 1 (n = 10) were partially milked at the first and second milking postpartum. Cows of group 2 (n = 10) were completely milked. Blood samples were collected from all animals 5–7 days before calving, within 30 min after calving, and 4, 8, 12, 16, 20, 24, 28, and 32 h after calving for determination of serum calcium (Ca), phosphorus (P), and magnesium (Mg) concentrations. Colostrum production was registered and sampled in the first and second milking. Concentration of Ca in colostrum was determined by atomic absorption spectrophotometry. Serum Ca and P concentrations decreased in both groups after parturition (P < 0.05) and remained low during 32 h postpartum with no difference observed between groups (P > 0.05). Serum concentrations of Mg were stable in all samples and no statistical difference was observed between groups (P > 0.05). Colostrum production was higher in completely milked cows only in the first postpartum milking (P < 0.05), but there was no difference between groups at the second milking. Total Ca secretion in colostrum was higher in the complete milking group at the first and second postpartum milking. Colostrum Ca secretion increased at the second milking with respect to the first one in both groups (P < 0.05). There was no correlation between serum Ca and colostrum Ca (P > 0.05). In this study, the partial milking of colostrum in the first and second milking postpartum did not prevent subclinical hypocalcemia in dairy cows.  


2014 ◽  
Vol 1 (2) ◽  
Author(s):  
Eligio Gabriel Salgado-Hernández ◽  
Jan Bouda ◽  
Adolfo Aparicio-Cecilio-A ◽  
Jaroslav Doubek ◽  
Francisco Hernany Velásquez-Forero

Subclinical hypocalcemia occurs frequently in dairy cows and predisposes them to reproductive pathologies. Prostaglandin F2α (PGF2α) improves uterine health and increases the level of serum calcitriol in other species. The aim of this study was to evaluate the effect of sodium cloprostenol on serum calcium, metabolites of vitamin D and reproductive variables. Eighty multiparous Holstein cows were selected and randomized into two groups. The cows in Group 1 (n = 38) were treated with 500 µg of I M sodium cloprostenol, a synthetic analog of PGF2α, at 1 and 48 h postpartum. Group 2 was the control group (n = 42). Blood samples were taken from 10 animals per group at 1, 3, 12, 24, 48 h and 7 d postcalving. The incidence of retained placenta, metritis and endometritis and the number of open days were recorded. The concentrations of Ca, P, Mg, calcidiol and calcitriol in the serum were evaluated using an analysis of variance for repeated measures design. The serum Ca concentration was increased up to normalized at day 7 in the PGF2α group compared with the level in the control group. PGF2α treatment increased the serum calcium concentration and reduced the number of open days, and thus, could be useful in preventing subclinical hypocalcemia and postpartum reproductive problems.


2014 ◽  
Vol 59 (No. 1) ◽  
pp. 11-18
Author(s):  
E.G. Salgado-Hernández ◽  
J. Bouda ◽  
A. Villa-Godoy ◽  
J.L. Romano-Muñoz ◽  
A.J. Gutiérrez-Chávez ◽  
...  

Concentrations of calcidiol, calcitriol, and minerals in blood serum and colostrum of 14 primiparous and 16 multiparous Holstein dairy cows during short-period prepartum and postpartum were determined and compared. Blood samples were collected between days 5 and 2 prepartum and 6 h, 12 h, 7 and 21 days postpartum. Nearly 66% of primiparous and 71% of multiparous cows had subclinical postpartum hypocalcemia. Prepartum serum calcium (Ca) and inorganic phosphorus (P) were higher in primiparous cows; Ca decreased in both groups at 6 and 12 h and returned to baseline values 7 days postpartum. Calcidiol and calcitriol concentrations were equal on day 5 prepartum in both groups. In multiparous cows, calcidiol and calcitriol concentration increased at 6 h postpartum and remained elevated at 12 h postpartum; there were no changes in primiparous cows for these analytes. The total secretion of Ca in the colostrum from the first milking was similar in both groups and positively correlated with serum Ca at 6 and 12 h after calving. It is concluded that postpartum increases in the calcidiol and calcitriol concentration were a normal response to the decrease of serum calcium concentration only in multiparous cows. The total Ca secretion in the colostrum of the first milking postpartum does not reflect the grade of hypocalcemia.


Endocrinology ◽  
1968 ◽  
Vol 83 (6) ◽  
pp. 1375-1376 ◽  
Author(s):  
BERNARD F. RICE ◽  
ROY PONTHIER ◽  
M. CLINTON MILLER

1996 ◽  
Vol 30 (9) ◽  
pp. 957-959 ◽  
Author(s):  
Hanan Gur ◽  
Yoav Paz ◽  
Yechezkel Sidi

OBJECTTVE: To report a case of acute dystonic reaction to methotrimeprazine in a patient with untreated hypoparathyroidism, emphasizing the potential increased sensitivity of hypocalcemic patients to the extrapyramidal adverse effects of antipsychotic drugs. CASE SUMMARY: An 80-year-old man who had untreated hypoparathyroidism and chronic hypocalcemia developed an acute dystonic reaction 20 minutes after ingestion of methotrimeprazine 25 mg. His medical history included an ill-defined psychiatric disorder for which he had been treated with methotrimeprazine several years earlier. The patient denied having any other diseases or taking any other medications. After 4 days, the disorientation, psychomotor restlessness, dystonic grimacing, protrusion of the tongue, and speech difficulties disappeared, despite a remaining low serum calcium concentration. DISCUSSION: A possible mechanism, by which striatal calmodulin-mediated adenylate cyclase activation is inhibited by the combined effects of phenothiazines and hypocalcemia, is discussed. CONCLUSIONS: In this patient, it is not possible to ascertain whether the dystonic reaction was due to hypocalcemia, phenothiazine administration, or both. However, it is suggested that patients with hypocalcemia may be sensitive to the extrapyramidal adverse effects of antipsychotics. In addition, acute unexpected dystonic reactions to a small dose of antipsychotics warrants measurement of the patient's serum calcium concentration.


1970 ◽  
Vol 16 (3) ◽  
pp. 226-228 ◽  
Author(s):  
Genevieve Farese ◽  
Milton Mager ◽  
William F Blatt

Abstract A rapid, simple procedure is described for separating diffusible from proteinbound serum calcium by centrifugation through high-flux ultrafiltration membranes. The mean normal value for ultrafilterable calcium was 57.1% (range 52 to 61%) of the total serum calcium concentration.


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