Relation of prophylactic medication to the occurrence of early seizures following craniocerebral trauma
1973 ◽
Vol 38
(2)
◽
pp. 155-158
◽
Keyword(s):
✓ In a series of 1614 cases of combat head injury incurred in Vietnam between 1967 and 1970, 70% received prophylatic anticonvulsant medication (diphenylhydantoin, 300 to 400 mg/day); 36 developed fits in the first week following injury. The prophylactic regimen had no recognizable effect. Therapeutic serum levels of anticonvulsants are not achieved for 2 or 3 weeks. Usefulness of dexamethasone in controlling brain swelling may be seriously impaired by diphenylhydantoin. Thus prophylaxis against early posttraumatic fits may not be practical or desirable.
1977 ◽
Vol 46
(2)
◽
pp. 256-258
◽
Keyword(s):
2003 ◽
Vol 98
(1)
◽
pp. 32-36
◽
Keyword(s):
1993 ◽
Vol 79
(3)
◽
pp. 354-362
◽
1987 ◽
Vol 66
(4)
◽
pp. 548-554
◽
1983 ◽
Vol 58
(1)
◽
pp. 45-50
◽
1979 ◽
Vol 51
(4)
◽
pp. 507-509
◽
Keyword(s):
1983 ◽
Vol 58
(5)
◽
pp. 672-677
◽
Keyword(s):
2005 ◽
Vol 102
(Special_Supplement)
◽
pp. 1-3
◽
Keyword(s):