The complexity of concurrent cerebral processes underlying driving makes such human behavior one of the most studied real-world activities in neuroergonomics. Several attempts have been made to decode, both offline and online, cerebral activity during car driving with the ultimate goal to develop brain-based systems for assistive devices. Electroencephalography (EEG) is the cornerstone of these studies providing the highest temporal resolution to track those cerebral processes underlying overt behavior. Particularly when investigating real-world scenarios as driving, EEG is constrained by factors such as robustness, comfortability, and high data variability affecting the decoding performance. Hence, additional peripheral signals can be combined with EEG for increasing replicability and the overall performance of the brain-based action decoder. In this regard, hybrid systems have been proposed for the detection of braking and steering actions in driving scenarios to improve the predictive power of the single neurophysiological measurement. These recent results represent a proof of concept of the level of technological maturity. They may pave the way for increasing the predictive power of peripheral signals, such as electroculogram (EOG) and electromyography (EMG), collected in real-world scenarios when informed by EEG measurements, even if collected only offline in standard laboratory settings. The promising usability of such hybrid systems should be further investigated in other domains of neuroergonomics.
Distinguishing Extravascular from Intravascular Ferumoxytol Pools within the Brain: Proof of Concept in Patients with Treated Glioblastoma
