Effect of Hyperbaric Oxygen Therapy (HBOT) on Insulin Resistance Associated with Abdominal Obesity in Wistar Rats with Dietary Sucrose-Induced Metabolic Syndrome

Background: Oral candidiasis generally caused by Candida albicans with prevalence of 30-50%. C. Albicans proliferation in the oral cavity was canducted by decreasing immune system of the host. Lymphocytes activation in immune system happened when there is a contact between host cell with cell wall of C. albicans as a result of C. albicans antigen. One of therapy to suppress the Candida infection sistemically is by giving hyperbaric oxygen therapy. Purpose: To determine the effects of giving hyperbaric oxygen therapy to the amount of lymphocytes in oral candidiasis immunosuppressed models. Methods: This research was post test only control group design. We used 12 wistar rats which were divided into 3 groups(n=4/3): K-(normal/ healthy wistar rats), K+(oral candidiasis immunosuppressed wistar rats), P1(oral candidiasis immunosuppressed wistar rats which were given hyperbaric oxygen therapy 5 days). K+ and P1 groups were immunosuppressed by giving dexamethasone 0,5mg/day/rat orally for 14 days, added with tetrasiklin 1 mg/day/rat. On the 3rd day immunosuppression, the rats were inducted with C.albicans smeared in the dorsum linguae once every two days for 12 days. Results: The data were analyzed with one way Anova test and showed significant difference among groups (p<0,05). To show the difference between each groups we used LSD test and showed significant difference (p<0,05) between K+ compared with P1, and K+ compared with K-. Conclusion: Hyperbaric oxygen therapy gives effect to the amount of lymphocytes in oral candidiasis immunosuppressed models. Keywords: Oral candidiasis, immunosuppressed, hyperbaric oxygen therapy, lymphocytes Correspondence: Agni Febrina Pargaputri, Department of Oral Biology Faculty of Dentistry, Jl. Arif Rahman Hakim 150, Surabaya, Indonesia. Phone: 031-5945864, fax: 031-5912191, Email: agni.febrina@hangtuah.ac.id

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Effect of hyperbaric oxygen therapy in rats with subtotal splenectomy preserving the inferior pole

Acta Cirurgica Brasileira ◽

10.1590/s0102-86502011000300002 ◽

2011 ◽

Vol 26 (3) ◽

pp. 156-164 ◽

Cited By ~ 9

Author(s):

Marcela Souza Lima Paulo ◽

Isabel Cristina Andreatta Lemos Paulo ◽

Tarcizo Afonso Nunes ◽

Alcino Lázaro da Silva ◽

Luiz Cálice Cintra ◽

...

Keyword(s):

Hyperbaric Oxygen ◽

Hyperbaric Oxygen Therapy ◽

Wistar Rats ◽

Oxygen Therapy ◽

Inferior Pole ◽

Group A ◽

Group B ◽

Oxygen Group ◽

Subtotal Splenectomy

PURPOSE: To evaluate the effect of hyperbaric oxygen therapy on the survival and weight of rats submitted to subtotal splenectomy and on the viability and growth of the inferior pole. METHODS: Forty Wistar rats underwent subtotal splenectomy with preservation of the inferior pole and distributed into two groups: Group A (n=20) - not treated with hyperbaric oxygen, Group B (n=20) - treated with hyperbaric oxygen. These groups were divided into two subgroups of 10 animals each, according to the time of euthanasia, 15th and 45th days. The survival and weight of the animals were recorded. The inferior pole was measured, weighed and morphologically analyzed. RESULTS: All animals survived. The weight of the animals increased in all subgroups, but decreased on the 10th day in the subgroups treated with hyperbaric oxygen (p<0.001). The viability of the inferior pole was more evident in animals treated on the 15th day, but did not differ on the 45th day. The growth of the inferior pole has not occurred on the 15th day but on the 45th day after surgery in untreated animals (p<0.01) and treated animals (p<0.05). Vascular and cellular increase in treated animals was significantly higher than in untreated ones. CONCLUSION: Hyperbaric oxygen therapy did not affect the survival of animals but reduced their weight. It improved the viability of the inferior splenic pole, but did not interfere with their growth.

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Combination Administration of Stichopus hermaniiGel and Hyperbaric Oxygen Therapy the number of fibroblasts in diabetes mellitus rats with periodontitis

DENTA ◽

10.30649/denta.v11i2.93 ◽

2019 ◽

Vol 11 (2) ◽

pp. 9

Author(s):

Faraziza Maulana ◽

Dian Mulawarmanti ◽

Fanny M. Laihad

Keyword(s):

Diabetes Mellitus ◽

Wound Healing ◽

Single Dose ◽

Adjuvant Therapy ◽

Hyperbaric Oxygen ◽

Hyperbaric Oxygen Therapy ◽

Wistar Rats ◽

Oxygen Therapy ◽

Male Wistar Rats ◽

Determine Effect

Background: Periodontitis is the most severe complication in oral cavity to diabetes mellitus. Stichopus hermanii contain GAG, a polysaccharide which very useful in wound healing. Hyperbaric oxygen therapy is effective repairing ischemia, hypoxia, and is used as adjuvant therapy. Purpose: To determine effect of administration of Stichopus hermanii (SH) 3% gel and hyperbaric oxygen therapy 3x30 minutes with 5 minute intervals in 7 consecutive days to the number of fibroblasts in ligament periodontal diabetes mellitus rats with periodontitis. Materials and Methods: The experiment design is factorial design. Rats are inducted with STZ single dose 65 mg/kgBB to make them suffer DM and are inducted with P.gingivalis 1x109sel/ml for 5 days straight to make them suffer periodontitis. 20 male wistar rats are divided into 5 groups. K- (control), K1 (STZ+P.Gingivalis), K2(STZ+P.Gingivalis+SH), K3(STZ+P.Gingivalis+HBO), K4(STZ+P.Gingivalis+SH+HBO). After 52 days treatment, rats is terminated to make a HPA Sample from the mandible and fibroblast is counted with 400x magnification. Result: One-way Annova here were significant differences (p<0,05) in K- (32.300 ± 11.381), K1 (31.725 ± 5.590), K2 (54.225 ± 7.165), K3 (49.725 ± 10.088), K4 (72.075 ± 9.342). Conclusion: administration of Stichopus hermanii 3% gel combination and 2.4 ATA hyperbaric oxygen 3x30 minutes a day with 5 minutes intervals in 7 consecutive days can increase the number of fibroblasts in diabetes mellitus rats with periodontitis. Keywords: Stichopus hermanii, hyperbaric oxygen, diabetes, periodontitis, fibroblasts Correspondence: Dian Mulawarmanti, Department of Oral Biology,Faculty of Dentistry, , Hang Tuah University, Arif Rahman Hakim 150, Surabaya, Phone 031-5945864, Email: <a href="mailto:[email protected]">[email protected]</a>

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Hyperbaric Oxygen Therapy Improves Cognition in CP

Pediatric News ◽

10.1016/s0031-398x(06)71567-3 ◽

2006 ◽

Vol 40 (12) ◽

pp. 52

Author(s):

DAMIAN MCNAMARA

Keyword(s):

Hyperbaric Oxygen ◽

Hyperbaric Oxygen Therapy ◽

Oxygen Therapy

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Hyperbaric oxygen therapy in mice injected with tetanus toxin

JAMA ◽

10.1001/jama.200.2.129 ◽

1967 ◽

Vol 200 (2) ◽

pp. 129-131

Author(s):

N. A. Christensen

Keyword(s):

Hyperbaric Oxygen ◽

Hyperbaric Oxygen Therapy ◽

Tetanus Toxin ◽

Oxygen Therapy

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Supplemental Material for Improvement of Memory Impairments in Poststroke Patients by Hyperbaric Oxygen Therapy

Neuropsychology ◽

10.1037/neu0000149.supp ◽

2014 ◽

Keyword(s):

Hyperbaric Oxygen ◽

Hyperbaric Oxygen Therapy ◽

Oxygen Therapy ◽

Memory Impairments

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Benefits of Hyperbaric Oxygen Therapy Still Doubtful

Deutsches Aerzteblatt Online ◽

10.3238/arztebl.2013.0372a ◽

2013 ◽

Author(s):

Ernst A. Chantelau

Keyword(s):

Hyperbaric Oxygen ◽

Hyperbaric Oxygen Therapy ◽

Oxygen Therapy

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Experience in Applying Hyperbaric Oxygen Therapy Using Portable Pressure Chambers for the Treatment of Patients with the Novel Coronavirus Infection COVID-19

Biomeditsina ◽

10.33647/2074-5982-16-2-39-46 ◽

2020 ◽

pp. 39-46

Author(s):

A. S. Samoilov ◽

Yu. D. Udalov ◽

M. V. Sheyanov ◽

A. V. Gholinsky ◽

A. B. Litvinenko

Keyword(s):

Oxygen Saturation ◽

Hyperbaric Oxygen ◽

Hyperbaric Oxygen Therapy ◽

Oxygen Therapy ◽

Capillary Blood ◽

Blood Hemoglobin ◽

Patient Groups ◽

Radiological Changes ◽

Coronavirus Infection ◽

Novel Coronavirus

This communication presents the experience of using mobile pressure chambers in patients with the confi rmed novel coronavirus infection in hospital settings. The obtained preliminary results indicate positive antihypoxic effects of hyperbaric oxygen therapy (HBO) applied in the form of increased saturation. After a session of HBO, patients demonstrated an increase in the oxygen saturation of capillary blood hemoglobin at the average level of 3.71 points. Differences between SatO2 levels prior to and following HBO treatment were signifi cant in the CT2, CT3 and CT4 groups (p0.05). As expected, the effi cacy of HBO in terms of the oxygen saturation of capillary blood hemoglobin was the greatest in the patient groups showing pronounced clinical and radiological changes in the lungs.

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An Evidence-Based Review of the Neurological Applications of Hyperbaric Oxygen Therapy. Part 1

Critical Reviews in Physical and Rehabilitation Medicine ◽

10.1615/critrevphysrehabilmed.v20.i3.40 ◽

2008 ◽

Vol 20 (3) ◽

pp. 237-275

Author(s):

Herbert B. Newton

Keyword(s):

Hyperbaric Oxygen ◽

Hyperbaric Oxygen Therapy ◽

Oxygen Therapy ◽

Evidence Based

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Pengaruh Pemberian Terapi Oksigen Hiperbarik Terhadap Kadar Kolesterol Total Pada Tikus Putih (Rattus novergicus) Jantan Galur Wistar Yang Di Induksi Diet Tinggi Lemak

Hang Tuah Medical journal ◽

10.30649/htmj.v16i1.56 ◽

2018 ◽

Vol 16 (1) ◽

pp. 1 ◽

Cited By ~ 1

Author(s):

AZRUL HILDAN SAFRIZAL

Keyword(s):

Cardiovascular Disease ◽

Total Cholesterol ◽

Cholesterol Level ◽

Hyperbaric Oxygen ◽

Hyperbaric Oxygen Therapy ◽

High Fat Diet ◽

Oxygen Therapy ◽

Total Cholesterol Level ◽

High Fat ◽

Cholesterol Levels

The pattern and lifestyle of today's society with the presence of an interner facility makes people spend more time sitting out than on exercise and increased consumption of high-fat foods may increase the risk of cardiovascular disease. An effective therapy is needed in preventing the occurrence of cardiovascular disease. Hyperbaric oxygen now starts to develop for the treatment of several diseases, which in turn can increase the gene forming antioxidant enzymes and ROS. To determine effect of hyperbaric oxygen therapy on total cholesterol levels of wistar white rats (Rattusnovergicus) induced bye high fat. The study was carried out in an expeative post test only group control of three groups. One group is given standard feed. All groups induced high-fat diet and standard feed. Of the two groups induced, one group was given hyperbaric oxygen therapy with a dose of 3 x 30 minutes for six days on day 7 at a blood test to determine total cholesterol levels. One way Anova parametric statistic test showed that p = 0.007 < α proved hypothesis that hyperbaric oxygen therapy giving effect to total cholesterol level of white mice of jantangalurist rings induced by high fat diet. Total cholesterol was significantly different between K (-) and K (+) and between K (-) and P. It was found that hyperbaric oxygen therapy had an effect on total cholesterol level dose of 3x30 minutes for six days.

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