Data Driven Modelling and Control of Batch Processes in the Pharmaceutical Industry

2012 ◽  
Vol 45 (15) ◽  
pp. 708-714 ◽  
Author(s):  
Jose E. Tabora
2021 ◽  
Vol 11 (4) ◽  
pp. 1829
Author(s):  
Davide Grande ◽  
Catherine A. Harris ◽  
Giles Thomas ◽  
Enrico Anderlini

Recurrent Neural Networks (RNNs) are increasingly being used for model identification, forecasting and control. When identifying physical models with unknown mathematical knowledge of the system, Nonlinear AutoRegressive models with eXogenous inputs (NARX) or Nonlinear AutoRegressive Moving-Average models with eXogenous inputs (NARMAX) methods are typically used. In the context of data-driven control, machine learning algorithms are proven to have comparable performances to advanced control techniques, but lack the properties of the traditional stability theory. This paper illustrates a method to prove a posteriori the stability of a generic neural network, showing its application to the state-of-the-art RNN architecture. The presented method relies on identifying the poles associated with the network designed starting from the input/output data. Providing a framework to guarantee the stability of any neural network architecture combined with the generalisability properties and applicability to different fields can significantly broaden their use in dynamic systems modelling and control.


2021 ◽  
pp. 110924
Author(s):  
Gulai Shen ◽  
Zachary E. Lee ◽  
Ali Amadeh ◽  
K. Max Zhang

Author(s):  
Nurali Virani ◽  
Devesh K. Jha ◽  
Zhenyuan Yuan ◽  
Ishana Shekhawat ◽  
Asok Ray

This paper addresses the problem of learning dynamic models of hybrid systems from demonstrations and then the problem of imitation of those demonstrations by using Bayesian filtering. A linear programming-based approach is used to develop nonparametric kernel-based conditional density estimation technique to infer accurate and concise dynamic models of system evolution from data. The training data for these models have been acquired from demonstrations by teleoperation. The trained data-driven models for mode-dependent state evolution and state-dependent mode evolution are then used online for imitation of demonstrated tasks via particle filtering. The results of simulation and experimental validation with a hexapod robot are reported to establish generalization of the proposed learning and control algorithms.


2013 ◽  
Vol 726-731 ◽  
pp. 2017-2021 ◽  
Author(s):  
Zhao Du ◽  
Xiang Ling Yuan ◽  
Ai Ling Ren ◽  
Feng Ying Fu

According to the pharmaceutical industry produce VOCs and stench of atmospheric environment pollution, combined with typical pharmaceutical biological fermentation and chemical synthesis process of VOCs and odour pollution are classified 4 types:fermentation tail gas, recycling of exhaust gas, exhaust gas and wastewater workshop stench. The control technology should be selected according to the four types of waste characteristics.


Author(s):  
Prashant Mhaskar ◽  
Abhinav Garg ◽  
Brandon Corbett

Author(s):  
Sten Bay J√∏rgensen ◽  
Dennis Bonn√© ◽  
Lars Gregersen

2018 ◽  
Vol 15 (3-1) ◽  
pp. 189-204 ◽  
Author(s):  
Roberto Moro Visconti ◽  
Giuseppe Montesi ◽  
Giovanni Papiro

The research question of this paper is concerned with the investigation of the links between Internet of Things and related big data as input parameters for stochastic estimates in business planning and corporate evaluation analytics. Financial forecasts and company appraisals represent a core corporate ownership and control issue, impacting on stakeholder remuneration, information asymmetries, and other aspects. Optimal business planning and related corporate evaluations derive from an equilibrated mix of top-down and bottom-up approaches. While the former follows a traditional dirigistic methodology where companies set up their strategic goals, the latter are grass-rooted with big data-driven timely evidence. Real options can be embedded in big data-driven forecasting to make expected cash flows more flexible and resilient, improving Value for Money of the investment and reducing its risk profile. More accurate and timely big data-driven predictions reduce uncertainties and information asymmetries, making risk management easier and decreasing the cost of capital. Whereas stochastic modeling is traditionally used for budgeting and business planning, this probabilistic process is seldom nurtured by big data that can refresh forecasts in real time, improving their predictive ability. Combination of big data and stochastic estimates for corporate appraisal and governance issues represents a methodological innovation that goes beyond the traditional literature and practice.


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