Temporomandibular joint dysfunction: A non-invasive approach towards the management of a long-standing condition

Degeneration of the articulating surfaces and pain associated with temporomandibular joint (TMJ) dysfunction are the primary symptoms of TMJ disorders (TMDs), where normal life activities such as eating, talking, and even sleeping may be drastically impaired [1–3]. To accelerate the discovery of effective therapeutic interventions for the treatment of TMD pain, we have been establishing a novel non-invasive approach for objectively assessing the presence of joint hypersensitivity. Our approach to identify chronic joint pain is based on evidence that all of the etiological factors associated with TMD pain implicate remodeling and degeneration of the joint in response to alterations in motion and loading. The injury model used for this study was a reversible, mechanical model through splint placement on the molars. It is hypothesized that arthrokinematic analysis will identify a specific pattern of functional changes that constitute a signature for the presence of irreversible damage.

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Hand-Carried Ultrasonography Instrumentation in the Diagnosis of Temporomandibular Joint Dysfunction

Methods and Protocols ◽

10.3390/mps4040081 ◽

2021 ◽

Vol 4 (4) ◽

pp. 81

Author(s):

Marco Severino ◽

Silvia Caruso ◽

Sofia Rastelli ◽

Roberto Gatto ◽

Tommaso Cutilli ◽

...

Keyword(s):

Temporomandibular Joint ◽

Correct Diagnosis ◽

Mechanical Problem ◽

Diagnostic Efficacy ◽

Temporomandibular Joint Dysfunction ◽

Non Invasive ◽

Disc Position ◽

High Level ◽

Opening And Closing ◽

Bone Structures

Internal derangement (ID) in the temporomandibular joint (TMJ) is defined as a mechanical problem of the joint that interferes with its function. It is attributed to an abnormal interaction among the articular disc, condyle, and joint eminence. The aim of this study is to evaluate diagnostic efficacy of non-invasive hand-carried ultrasonography instrumentation (US) to provide high-level images for a correct diagnosis of ID. Twenty-eight ID patients, 15 female and 13 males, were examined both clinically and by MRI images in order to achieve a diagnosis of ID (using Helkimo index). Then, they were submitted to US examination with a 12 MHz transducer by using hand-carried instrumentation by a clinician that was blind to their diagnosis and clinical data. TMJ US examination was performed with the mouth closed and mouth open, with proper technique. Each position was then evaluated with two different orientations of the transducer. US showed acceptable results in identifying bone structures. Lower values of diagnostic efficacy were obtained for disc position during joint movements with respect to MRI images. MRI still represents the gold standard for the identification of joint structures. If not corroborated by clinical and anamnestic data, the diagnostic efficacy of US in identifying the position of the disc during opening and closing jaw movements appears limited than compared to MRI.

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Non-invasive approach in the treatment of temporomandibular joint osteoarthritis

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh200611079m ◽

2020 ◽

pp. 79-79

Author(s):

Andjela Milojevic-Samanovic ◽

Dejan Zdravkovic ◽

Stefan Velickovic ◽

Milica Jovanovic ◽

Marko Milosavljevic

Keyword(s):

Temporomandibular Joint ◽

Muscle Tension ◽

Masticatory Muscles ◽

Invasive Approach ◽

Non Invasive ◽

Temporomandibular Joint Osteoarthritis ◽

Patient Reported ◽

Orofacial Region ◽

The Right ◽

Bone Structures

Introduction. Temporomandibular dysfunction (TMD) is a set of disorders that involve the masticatory muscles, the temporomandibular joint (TMJ) and its associated structures. Osteoarthritis (OA), as one of the forms of TMD, leads to permanent changes in the bone structures of TMJ. These changes can be the cause of serious functional disorders of the TMJ. Case outline. This article describes a case of a 24-year-old female patient who sought help due to pain and swelling in the area of the right and left TMJ, accompanied by muscular tension, severe headaches, which did not respond to medication. ?fter establishing the diagnosis, we have applied a therapy in the treatment of the bilateral OA of TMJ, where we used non-invasive methods. Six months later, the patient reported the absence of pain, swelling, headache, and muscle tension in the orofacial region. Conclusion. There is no ?gold standard? for the management of ?? of ???. In our study, non-invasive therapy had a positive effect, where we achieved success in eliminating pain, increasing range of motion of the lower jaw, stopping the progression of the disease and advancing quality of life.

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Salivary cortisol as a non-invasive approach to assess stress in dystocic dairy calves

Scientific Reports ◽

10.1038/s41598-021-85666-9 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Levente Kovács ◽

Fruzsina Luca Kézér ◽

Szilárd Bodó ◽

Ferenc Ruff ◽

Rupert Palme ◽

...

Keyword(s):

Birth Weight ◽

Body Condition ◽

Salivary Cortisol ◽

Sampling Period ◽

Dairy Calves ◽

Birth Process ◽

Invasive Approach ◽

Non Invasive ◽

Saliva Cortisol ◽

Cortisol Levels

AbstractThe intensity and the magnitude of saliva cortisol responses were investigated during the first 48 h following birth in newborn dairy calves which underwent normal (eutocic, EUT, n = 88) and difficult (dystocic, DYS, n = 70) calvings. The effects of parity and body condition of the dam, the duration of parturition, the time spent licking the calf, the sex and birth weight of the calf were also analyzed. Neonatal salivary cortisol concentrations were influenced neither by factors related to the dam (parity, body condition) nor the calf (sex, birth weight). The duration of parturition and the time spent licking the calf also had no effect on salivary cortisol levels. Salivary cortisol concentrations increased rapidly after delivery in both groups to reach their peak levels at 45 and 60 min after delivery in EUT and DYS calves, respectively supporting that the birth process means considerable stress for calves and the immediate postnatal period also appears to be stressful for newborn calves. DYS calves exhibited higher salivary cortisol concentrations compared to EUT ones for 0 (P = 0.022), 15 (P = 0.016), 30 (P = 0.007), 45 (P = 0.003), 60 (P = 0.001) and 120 min (P = 0.001), and for 24 h (P = 0.040), respectively. Peak levels of salivary cortisol and the cortisol release into saliva calculated as AUC were higher in DYS than in EUT calves for the 48-h of the sampling period (P = 0.009 and P = 0.003, respectively). The greater magnitude of saliva cortisol levels in DYS calves compared to EUT ones suggest that difficult parturition means severe stress for bovine neonates and salivary cortisol could be an opportunity for non-invasive assessment of stress during the early neonatal period in cattle.

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Possibilities and limitations in the kinetic treatment of the temporomandibular joint dysfunction in rheumatic patients

2015 E-Health and Bioengineering Conference (EHB) ◽

10.1109/ehb.2015.7391456 ◽

2015 ◽

Author(s):

Maria Daniela Craciun ◽

Rodica Marieta Chiriac

Keyword(s):

Temporomandibular Joint ◽

Temporomandibular Joint Dysfunction ◽

Kinetic Treatment ◽

Rheumatic Patients

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Temporomandibular joint dysfunction following the use of a supraglottic airway device during general anaesthesia: a prospective observational study

Anaesthesia ◽

10.1111/anae.15533 ◽

2021 ◽

Author(s):

N. Akhtar ◽

N. Ungureanu ◽

S. Cakir ◽

U. Ansari ◽

T.‐Y. Mohamed ◽

...

Keyword(s):

Observational Study ◽

Temporomandibular Joint ◽

General Anaesthesia ◽

Prospective Observational Study ◽

Airway Device ◽

Supraglottic Airway ◽

Supraglottic Airway Device ◽

Temporomandibular Joint Dysfunction

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The Cat Mandible (II): Manipulation of the Jaw, with a New Prosthesis Proposal, to Avoid Iatrogenic Complications

Animals ◽

10.3390/ani11030683 ◽

2021 ◽

Vol 11 (3) ◽

pp. 683

Author(s):

Matilde Lombardero ◽

Mario López-Lombardero ◽

Diana Alonso-Peñarando ◽

María del Mar Yllera

Keyword(s):

Imaging Techniques ◽

Recovery Period ◽

Prosthesis Design ◽

Patient Specific ◽

Mandibular Fractures ◽

Rigid Fixation ◽

Invasive Approach ◽

Non Invasive ◽

Iatrogenic Complications ◽

Mandibular Body

The cat mandible is relatively small, and its manipulation implies the use of fixing methods and different repair techniques according to its small size to keep its biomechanical functionality intact. Attempts to fix dislocations of the temporomandibular joint should be primarily performed by non-invasive techniques (repositioning the bones and immobilisation), although when this is not possible, a surgical method should be used. Regarding mandibular fractures, these are usually concurrent with other traumatic injuries that, if serious, should be treated first. A non-invasive approach should also first be considered to fix mandibular fractures. When this is impractical, internal rigid fixation methods, such as osteosynthesis plates, should be used. However, it should be taken into account that in the cat mandible, dental roots and the mandibular canal structures occupy most of the volume of the mandibular body, a fact that makes it challenging to apply a plate with fixed screw positions without invading dental roots or neurovascular structures. Therefore, we propose a new prosthesis design that will provide acceptable rigid biomechanical stabilisation, but avoid dental root and neurovascular damage, when fixing simple mandibular body fractures. Future trends will include the use of better diagnostic imaging techniques, a patient-specific prosthesis design and the use of more biocompatible materials to minimise the patient’s recovery period and suffering.

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Holistic description of new deep sea megafauna (Cephalopoda: Cirrata) using a minimally invasive approach

BMC Biology ◽

10.1186/s12915-021-01000-9 ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Alexander Ziegler ◽

Christina Sagorny

Keyword(s):

Minimally Invasive ◽

Dna Barcoding ◽

Deep Sea ◽

Imaging Techniques ◽

Structural Complexity ◽

Micro Computed Tomography ◽

Invasive Approach ◽

Non Invasive ◽

Additional Support ◽

Holistic Description

Abstract Background In zoology, species descriptions conventionally rely on invasive morphological techniques, frequently leading to damage of the specimens and thus only a partial understanding of their structural complexity. More recently, non-destructive imaging techniques have successfully been used to describe smaller fauna, but this approach has so far not been applied to identify or describe larger animal species. Here, we present a combination of entirely non-invasive as well as minimally invasive methods that permit taxonomic descriptions of large zoological specimens in a more comprehensive manner. Results Using the single available representative of an allegedly novel species of deep-sea cephalopod (Mollusca: Cephalopoda), digital photography, standardized external measurements, high-field magnetic resonance imaging, micro-computed tomography, and DNA barcoding were combined to gather all morphological and molecular characters relevant for a full species description. The results show that this specimen belongs to the cirrate octopod (Octopoda: Cirrata) genus Grimpoteuthis Robson, 1932. Based on the number of suckers, position of web nodules, cirrus length, presence of a radula, and various shell characters, the specimen is designated as the holotype of a new species of dumbo octopus, G. imperator sp. nov. The digital nature of the acquired data permits a seamless online deposition of raw as well as derived morphological and molecular datasets in publicly accessible repositories. Conclusions Using high-resolution, non-invasive imaging systems intended for the analysis of larger biological objects, all external as well as internal morphological character states relevant for the identification of a new megafaunal species were obtained. Potentially harmful effects on this unique deep-sea cephalopod specimen were avoided by scanning the fixed animal without admixture of a contrast agent. Additional support for the taxonomic placement of the new dumbo octopus species was obtained through DNA barcoding, further underlining the importance of combining morphological and molecular datasets for a holistic description of zoological specimens.

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