scholarly journals A Gyssens Evaluation On Antibiotics Usage On Inpatients With Urinary Tract Infection In Hospital X, Central Jakarta, on January 2017 – June 2019

2020 ◽  
Vol 5 (3) ◽  
pp. 96-102
Author(s):  
Henny Tannady Tan ◽  
Ade Dharmawan ◽  
Agus Cahyadi ◽  
Nicolas Layanto ◽  
Elisabeth Harahap

Urinary tract infections are infections from the bladder to the renal parenchyma, and can affect all ages. Empirical therapy can reduce morbidity, but due to the use of antibiotics that are not appropriate will have an impact on resistance that will cause increase morbidity, mortality, and health costs. In the Southeast Asian region, high use of antibiotics were found almost more than 80% in various provinces in Indonesia. This study aims to assess the appropriatness use of antibiotics in hospitalized patients with UTIs in the District Hospital X in the period January 2017 - June 2019 using gyssens criteria. This is retrospective study. Research data sourced from medical records. Data was collected and assessed with Gyssens flow, then processed using Microsoft Excel. The results found 15 cases (46.88%) with the appropriate use (category 0), 3 cases (9.37%) incorrect interval (category IIB), 1 case (3.33%) incorrect dosage (category IIA ), 10 cases (31.25%) too short given (category IIIB), 3 cases (9.37%) too long given (category IIIA). Empirical therapy inpatients with diagnosis urinary tract infections atvDistrict Hospital X, 46.8% of antibiotics were used appropriately.

2014 ◽  
Vol 27 (6) ◽  
pp. 737 ◽  
Author(s):  
Rui Passadouro ◽  
Raquel Fonseca ◽  
Felícia Figueiredo ◽  
Andreia Lopes ◽  
Cristina Fernandes

<strong>Introduction:</strong> The urinary tract infections, after respiratory infections, are the most common in the community. The knowledge about the prevalence of microbial strains and their antibiotic susceptibility is crucial to establish an effective empirical therapy. The aim of this study was to determine the antibiotic susceptibility patterns of bacterial strains isolated from positive urine cultures performed in patients from the central region of Portugal.<br /><strong>Material and Methods:</strong> We carried out a documental analysis of 6008 urine bacteriological exams, to be made available to physicians, most of which run through the automated system VITEK 2, bioMérieux. The majority (80%) of the urine bacteriological exams were from female. Escherichia coli was the most prevalent bacterial pathogen (65.9%), followed by Klebsiella spp (12%).<br /><strong>Results:</strong> Nitrofurantoin showed high levels of activity (96%) for Escherichia coli, as well as Fosfomycin (96.6%). Amoxicillin-clavulanic acid presents an activity level of only 81.1% for the same germ. Quinolones exhibit efficacy to only 78% of the strains of Escherichia coli, below the Fosfomycin and Nitrofurantoin. Nitrofurantoin showed high levels of activity (96%) for E. coli as well as Fosfomycin (96.6%). Amoxicillin-Clavulanic Acid presents a level of activity of only 81.1% for the same germ. The quinolones have a efficacy for only 78% of strains of E. coli, lower than Fosfomycin.<br /><strong>Discussion:</strong> Escherichia Coli was the most prevalent uropathogen (65.9%). High efficacy against this pathogenic agent was found for Fosfomycin (96.6%) and Nitrofurantoin (96%).<br /><strong>Conclusion:</strong> Further antimicrobial surveillance studies should be developed, in order to formulate local empirical therapy<br />recommendations for optimized therapeutical choices.<br /><strong>Keywords:</strong> Urinary Tract Infections; Drug Resistance, Bacterial; Anti-Bacterial Agents; Community-Acquired Infections.<br />


Author(s):  
Fatema Tabassum ◽  
Most. Nazma V ◽  
Md. Imran Nur Manik

Background: Urinary tract infections (UTIs) are the major health problems in young population. The aim of the study is to determine the knowledge and awareness about UTI among the university students of Bangladesh.Methods: The survey carried out among 403 students of different private universities of department of Pharmacy. Data were collected using structured questionnaires containing 6 questions related to the students’ demographics and 10 questions related to the knowledge and 6 questions related awareness to UTI. Data was analyzed by the Microsoft Excel version 10.Results: Among the respondents there were 61.04% female, majority of them were unmarried (93.80%) and the average limit for age was found to be 21 years. The result showed that 76.92% of respondents correctly identified bacteria as the principle pathogens forming UTIs and 80.15% suggested antibacterial drugs for the treatment of UTIs. 60.04% showed poor knowledge on the further consequences of untreated UTIs in the long run and 51.86% don’t know the adverse effect of urinary retention. This study showed that cumulatively 77.79% respondents had positive attitude towards the measures against UTIs. Among the subjects 71.46% are against holding urine , 93.80%  thinks drinking plenty of water is good for heath, 94.79% wanted to contact the doctor when get ill.Conclusions: Short-term morbidity in terms of fever, dysuria, and lower abdominal pain (LAP) and may result in permanent scarring of the kidney may caused by UTIs. Students must be made aware of these symptoms and their causes and also aware about the prevention of UTIs to decrease the morbidity rate. 


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