scholarly journals Effect of ellagic acid on body fat and triglyceride reduction in healthy overweight volunteers: a randomized, double-blind, placebo-controlled parallel group study

2020 ◽  
Vol 10 (4) ◽  
pp. 180
Author(s):  
Yoshiaka Shiojima
Keyword(s):  
Body Weight ◽  
Waist Circumference ◽  
Body Fat ◽  
Visceral Fat ◽  
Ellagic Acid ◽  
Hip Circumference ◽  
Anthropometric Parameters ◽  
Double Blind ◽  
Irvingia Gabonensis ◽  
Main Meal

Background: Worldwide, those categorized as overweight or obese are increasing at an alarming rate, posing a serious public health problem.  Current management methods vary, ranging from surgery, dieting and exercise, to the use of synthetic and natural compounds.  Previous studies reported the use of an Irvingia gabonensis extract containing ellagic acid in reducing weight and other related parameters in overweight participants. The present study investigated the efficacy of ellagic acid on anthropometric parameters as well as body fat ratio and blood triglyceride levels in otherwise healthy overweight Japanese adults.Participants and Methods: Overall, 32 participants (23 males and 9 females) aged between 20 and 64 years with a BMI of 25 or more but less than 30 kg/m2 and a visceral fat area of 80 cm2 or more were included in this randomized double-blind clinical trial.  The 20-week intervention involved two groups of participants -placebo group and ellagic acid (3.0 mg per day) group.  The placebo or ellagic acid was taken daily with water 30 minutes before the main meal.  At baseline (T0) and at 6 and 12 weeks, anthropometric measurements (body weight, BMI, body fat ratio, waist circumference, hip circumference), CT scans and blood triglyceride levels were measured. Results: Compared to the placebo, ellagic acid brought about statistically significant reductions in body fat ratio, triglycerides, body weight, BMI, waist circumference, hip circumference and visceral fat over the twelve-week trial period.Conclusion: The use of 3.0 mg ellagic acid daily for a 12-week period was effective in reducing body fat ratio and blood triglycerides as well as other anthropometric parameters, confirming the potential use of ellagic acid in the management of overweight patients. Keywords: Ellagic acid, Irvingia gabonensis, overweight, obesity, body fat, triglyceride, body weight, metabolic syndrome.

scholarly journals Impact of a program based in eating habits and physiotherapy on anthropometric parameters in patients with coronary artery disease: randomized controlled trial

2021 ◽  
Vol 20 (Supplement_1) ◽  
Author(s):  
E Munoz-Gomez ◽  
N Sempere-Rubio ◽  
J Blesa ◽  
P Iglesias ◽  
L Mico ◽  
...  
Keyword(s):  
Waist Circumference ◽  
Muscle Mass ◽  
Body Fat ◽  
Visceral Fat ◽  
Eating Habits ◽  
Controlled Trial ◽  
Hip Circumference ◽  
Anthropometric Parameters ◽  
Randomized Controlled ◽  
Artery Disease

Abstract Funding Acknowledgements Type of funding sources: None. Introduction. On the one hand, physical training such as High intensity interval training (HIIT) and on the other, eating habits, it is often prescribed to patients with coronary artery disease (CAD). Nevertheless, the combination of HIIT and eating habits in CAD with percutaneous coronary intervention (PCI) there is no consensus on using a combined protocol of both. Purpose. The purpose of this study was to evaluate the impact of an HIIT program with eating habits, with a program based in HIIT, on anthropometric parameters in CAD patients with PCI. Methods. A randomized controlled trial was carried out in a hospital.  44 patients with CAD and PCI were recruited. All participants signed an informed consent. Patients were randomly allocated to a HIIT group (HIIT, n = 22, 81.8% men, 62.05 ± 4.9 years) or to a Dietary education and HIIT (DEHIIT) group (n = 22, 81.8% men, 60.2 ± 5.6 years). HIIT consisted of a 3-month physiotherapy program, twice a week for one hour, at 85-95% peak heart rate. DEHIIT consisted of a multidisciplinary program, including the same HIIT program explained, plus eating habits. Body composition (weight, BMI, % body fat, % visceral fat, muscle mass) and waist circumference, hip circumference and Waste-to-Hip Ratio (WHR) were evaluated at baseline and at week 12. Results. At the end of the program, DEHIIT significantly decreased all anthropometrics parameters except muscle mass. The following parameters decreased: weight (p ≤ 0.001), BMI (p ≤ 0.001), body fat (p ≤ 0.001), visceral fat (p ≤ 0.001), waist circumference (p ≤ 0.001), hip circumference (p = 0.043) and WHR (p ≤ 0.001). Instead, the muscle mass increased  significantly (p ≤ 0.001). When comparing between groups, DEHIIT did not show significant differences weight (p = 0.575), BMI (p = 0.404), % body fat (p = 0.217), muscle mass (p = 0.508), waist circumference (p = 0.165), hip circumference (p = 0.307), WHR (p = 0.379), except for presenting less visceral fat (p = 0.040) than HIIT. Conclusions HIIT programme with eating habits reducing visceral fat in CAD patients with PCI compared to a HIIT-only program.

scholarly journals Resistin levels in hyperthyroid patients before and after restoration of thyroid function: relationship with body weight and body composition

2005 ◽  
Vol 153 (2) ◽  
pp. 217-221 ◽  
Author(s):  
Gerasimos E Krassas ◽  
Nikolaos Pontikides ◽  
Kostas Loustis ◽  
Georgios Koliakos ◽  
Theodoros Constantinidis ◽  
...  
Keyword(s):  
Body Weight ◽  
Waist Circumference ◽  
Thyroid Hormones ◽  
Body Fat ◽  
Energy Homeostasis ◽  
Peptide Hormone ◽  
Antithyroid Drugs ◽  
Anthropometric Parameters ◽  
Before And After ◽  
Hyperthyroid Patients

Background: Resistin is a recently discovered peptide hormone that belongs to a family of tissue-specific resistin-like molecules. To date, very few studies have reported on resistin concentrations in hyperthyroid patients, and they present controversial results. Objectives: To undertake a controlled, prospective study to investigate resistin concentrations in hyperthyroidism before and after restoration of euthyroidism and to correlate the results with body weight, body fat, waist circumference and body mass index (BMI). Patients and Methods: A total of 43 hyperthyroid patients (12 men and 31 women) were investigated, in addition to 23 controls. Anthropometric parameters and resistin concentrations were measured. All the patients commenced taking antithyroid drugs and 3–4 months later the same investigations were performed in 36 of the 43 individuals. Results: Hyperthyroid patients exhibited increased resistin concentrations in comparison with controls. Normalization of thyroid hormones was accompanied by a significant decrease in resistin concentration. A sex difference was also found, men showing a significant decrease in resistin concentrations, whereas in women no such difference was found. Resistin concentrations did not correlate with different anthropometric parameters, age and thyroid hormones, either before or after treatment. Conclusions: This study demonstrates for the first time that, although resistin concentrations are increased in hyperthyroidism, they are not associated with body weight, body fat, waist circumference or BMI, which makes it unlikely that resistin plays a crucial part in thermogenesis and energy homeostasis in thyrotoxic patients.

scholarly journals Daily supplementation with the Lab4P probiotic consortium induces significant weight loss in overweight adults

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
D. R. Michael ◽  
T. S. Davies ◽  
A. A. Jack ◽  
G. Masetti ◽  
J. R. Marchesi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Waist Circumference ◽  
Normal Diet ◽  
Controlled Study ◽  
Hip Circumference ◽  
Double Blind ◽  
The Impact ◽  
Overweight Adults ◽  
Diet And Lifestyle

AbstractThis 9-month randomised, parallel, double-blind, single-centre, placebo-controlled study (PROBE, ISRCTN18030882) assessed the impact of probiotic supplementation on bodyweight. Seventy overweight Bulgarian participants aged 45–65 years with BMI 25–29.9 kg/m2 received a daily dose of the Lab4P probiotic comprising lactobacilli and bifidobacteria (50 billion cfu/day). Participants maintained their normal diet and lifestyle over the duration of the study. The primary outcome was change from baseline in body weight and secondary outcomes included changes in waist circumference, hip circumference and blood pressure. A significant between group decrease in body weight (3.16 kg, 95% CI 3.94, 2.38, p < 0.0001) was detected favouring the probiotic group. Supplementation also resulted in significant between group decreases in waist circumference (2.58 cm, 95% CI 3.23, 1.94, p < 0.0001) and hip circumference (2.66 cm, 95% CI 3.28, 2.05, p < 0.0001) but no changes in blood pressure were observed. These findings support the outcomes of a previous shorter-term Lab4P intervention study in overweight and obese participants (PROMAGEN, ISRCTN12562026). We conclude that Lab4P has consistent weight modulation capability in free-living overweight adults.

scholarly journals Computer-aided tomography and anthropometry in the diagnosis of visceral obesity in men

2001 ◽  
Vol 47 (3) ◽  
pp. 18-22
Author(s):  
I. V. Dvoryashina ◽  
T. N. Ivanova ◽  
I. A. Rogozina ◽  
A. A. Korobitsyn
Keyword(s):  
Body Weight ◽  
Waist Circumference ◽  
Computer Tomography ◽  
Visceral Fat ◽  
Abdominal Cavity ◽  
Visceral Obesity ◽  
Fatty Tissue ◽  
Anthropometric Parameters ◽  
Fat Depots ◽  
Sagittal Diameter

A total of 153 men with obesity of different degree and 51 men with normal body weight aged 40-60 years were examined in order to detect a relationship between anthropometric parameters and computer tomography data characterizing the accumulation of abdominal fat at different sites. Body weight, height, waist and hips circumferences, and cutaneo-fatty folds were measured. The area of total abdominal fatty tissue, vis- ceral and subcutaneous fat were evaluated by computer tomography; scanning of the abdominal cavity showed images of two sections (at the levels of the 2-3 and 4-5 lumbar verte brae). The results indicate that abdominal obesity in men is characterized by predominant accumulation of fatty tissue in visceral fat depots. The most informative anthropometric markers of the degree of visceral fat accumulation are sagittal diameter and waist circumference. Sagittal diameter 21.1 cm and waist circumference 95.9 cm and more indicate pronounced visceral obesity (93.2 and 88.9% examinees, respectively). These anthropometric parameters are recommended for the diagnosis of visceral obesity in clinical practice.

scholarly journals Intake of ruminanttrans-fatty acids, assessed by diet history interview, and changes in measured body size, shape and composition

2015 ◽  
Vol 19 (3) ◽  
pp. 494-502 ◽  
Author(s):  
Camilla P Hansen ◽  
Berit L Heitmann ◽  
Thorkild IA Sørensen ◽  
Kim Overvad ◽  
Marianne U Jakobsen
Keyword(s):  
Fatty Acids ◽  
Body Weight ◽  
Body Size ◽  
Waist Circumference ◽  
Body Fat ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Hip Circumference ◽  
Diet History

AbstractObjectiveStudies have suggested that total intake oftrans-fatty acids (TFA) is positively associated with changes in body weight and waist circumference, whereas intake of TFA from ruminant dairy and meat products (R-TFA) has not been associated with weight gain. However, these previous studies are limited by self-reported measures of body weight and waist circumference or by a cross-sectional design. The objective of the present study was to investigate if R-TFA intake was associated with subsequent changes in anthropometry (body weight, waist and hip circumference) measured by technicians and body composition (body fat percentage).DesignA 6-year follow-up study. Information on dietary intake was collected through diet history interviews, and anthropometric and bioelectrical impedance measurements were obtained by trained technicians at baseline (1987–1988) and at follow-up (1993–1994). Multiple regression with cubic spline modelling was used to analyse the data.SettingCopenhagen County, Denmark.SubjectsTwo hundred and sixty-seven men and women aged 35–65 years from the Danish MONICA (MONItoring of trends and determinants in CArdiovascular diseases) cohort.ResultsThe median R-TFA intake was 1·3 g/d (5th, 95th percentile: 0·4, 2·7 g/d) or 0·6 % of the total energy intake (5th, 95th percentile: 0·2, 1·1 %). No significant associations were observed between R-TFA intake and changes in body weight, waist and hip circumference or body fat percentage.ConclusionsR-TFA intake within the range present in the Danish population was not significantly associated with subsequent changes in body size, shape or composition and the 95 % confidence intervals indicate that any relevant associations are unlikely to have produced these observations.

scholarly journals The effect of extracts of Irvingia gabonensis (IGOB131) and Dichrostachys glomerata (Dyglomera™) on body weight and lipid parameters of healthy overweight participants

2015 ◽  
Vol 5 (6) ◽  
pp. 200 ◽  
Author(s):  
Boris Azantsa ◽  
Dieudonne Kuate ◽  
Raoul Chakokam ◽  
Ghislain Paka ◽  
Barbara Bartholomew ◽  
...  
Keyword(s):  
Blood Lipids ◽  
Blood Lipid ◽  
Hip Circumference ◽  
Obese People ◽  
Double Blind ◽  
Once Daily ◽  
Double Blind Placebo ◽  
Irvingia Gabonensis ◽  
Main Meal ◽  
Lipid Parameters

Background: Previous work reported the benefits of extracts of 2 Cameroonian spices – Irvingia gabonensis and Dichrostachys glomerata— on obese people with metabolic syndrome. Considering the physio-metabolic changes that accompany obesity, the present study investigates the effects of these extracts on healthy overweight participants over an 8-week test period.Methods: The study was an 8 week randomized double-blind, placebo controlled design involving 48 overweight (BMI 26 – 30) participants (27 females and 19 males), divided into 3 groups – placebo, 300 mg I. gabonensis extract (IGOB131), or 300 mg D. glomerata extract (DyglomeraTM). Capsules containing the placebo or the test formulations were administered once daily before the main meal of the day. No major dietary changes or changes in physical activity were demonstrated during the study. Weight and blood lipid parameters were measured at baseline, and at the 4 and 8 weeks interval.Results: Compared to the placebo group, there were significant (p<0.05) reductions in weight of participants in both test groups over the 8 week period. However, these significant changes were not observed in the initial 4 weeks, even though the lipid parameters in the test groups changed significantly (p<0.05).Conclusion: The extracts of Irvingia gabonensis and Dichrostachys glomerata, at a dose of 300 mg per day, were effective in reducing weight and positively modifying lipid parameters in healthy overweight participants.Keywords: Overweight, Dichrostachys, Irvingia, waist-hip circumference, blood lipids.

scholarly journals Effects of Triphala on Lipid and Glucose Profiles and Anthropometric Parameters: A Systematic Review

2021 ◽  
Vol 26 ◽  
pp. 2515690X2110110
Author(s):  
Wiraphol Phimarn ◽  
Bunleu Sungthong ◽  
Hiroyuki Itabe
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Blood Glucose ◽  
Waist Circumference ◽  
Lipid Profile ◽  
Body Mass ◽  
The Body ◽  
Current Evidence ◽  
Diabetic Patients ◽  
Anthropometric Parameters

Aim. The efficacy of triphala on lipid profile, blood glucose and anthropometric parameters and its safety were assessed. Methods. Databases such as PubMed, ScienceDirect, Web of Science, and Thai Library Integrated System (ThaiLIS) were systematically searched to review current evidence of randomized controlled trials (RCT) on triphala. RCTs investigating the safety and efficacy of triphala on lipid profile, blood glucose and anthropometric parameters were included. Study selection, data extraction, and quality assessment were performed independently by 2 authors. Results. Twelve studies on a total of 749 patients were included. The triphala-treated groups showed significantly reduced low-density lipoprotein-cholesterol, total cholesterol and triglyceride in 6 studies. Five RCTs demonstrated triphala-treated groups led to statistically significant decrease in body weight, body mass index and waist circumference of obese patients. Moreover, triphala significantly decreased fasting blood glucose level in diabetic patients but not in people without diabetes. No serious adverse event associated with triphala was reported during treatment. Conclusions. This review summarized a current evidence to show triphala might improve the lipid profile, blood glucose, the body weight, body mass index and waist circumference under certain conditions. However, large well-designed RCTs are required to confirm this conclusion.

The Influence of Age, Sex and Body Mass Index on the Effectiveness of Brisk Walking for Obesity Management in Adults: A Systematic Review and Meta-Analysis

2017 ◽  
Vol 14 (5) ◽  
pp. 389-407 ◽  
Author(s):  
Leon Mabire ◽  
Ramakrishnan Mani ◽  
Lizhou Liu ◽  
Hilda Mulligan ◽  
David Baxter
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Waist Circumference ◽  
Body Fat ◽  
Fat Mass ◽  
Fat Free Mass ◽  
Body Fat Percentage ◽  
Brisk Walking ◽  
Obesity Management ◽  
Fat Percentage

Background:Brisk walking is the most popular activity for obesity management for adults. We aimed to identify whether participant age, sex and body mass index (BMI) influenced the effectiveness of brisk walking.Methods:A search of 9 databases was conducted for randomized controlled trials (RCTs). Two investigators selected RCTs reporting on change in body weight, BMI, waist circumference, fat mass, fat-free mass, and body fat percentage following a brisk walking intervention in obese adults.Results:Of the 5072 studies screened, 22 met the eligibility criteria. The pooled mean differences were: weight loss, –2.13 kg; BMI, –0.96 kg/m2; waist circumference, –2.83 cm; fat mass, –2.59 kg; fat-free mass, 0.29 kg; and body fat percentage, –1.38%. Meta-regression of baseline BMI showed no effect on changes.Conclusions:Brisk walking can create a clinically significant reduction in body weight, BMI, waist circumference, and fat mass for obese men and women aged under 50 years. Obese women aged over 50 years can achieve modest losses, but gains in fat-free mass reduce overall change in body weight. Further research is required for men aged over 50 years and on the influence of BMI for all ages and sexes.

scholarly journals Waist circumference and waist-hip ratio as screening tools for hypertension in children aged 6–11 years

2019 ◽  
Vol 59 (5) ◽  
pp. 265-70
Author(s):  
Esti Istiqomah ◽  
Dida A. Gurnida ◽  
Dany Hilmanto ◽  
Dzulfikar Djalil Lukmanul Hakim ◽  
Prima Nanda Fauziah
Keyword(s):  
Waist Circumference ◽  
Prevalence Ratio ◽  
Screening Tools ◽  
Hip Circumference ◽  
Roc Curve Analysis ◽  
Anthropometric Parameters ◽  
Predictive Values ◽  
Waist Hip Ratio ◽  
Hypertensive Group ◽  
Hypertension In Children

Background Hypertension in children is associated with obesity. 7 The renin-angiotensin-aldosterone system has been associated with intra-abdominal fat tissue. Anthropometric parameters for determining nutritional status include waist circumference and waist-hip ratio. Many studies have shown that waist circumference and waist-hip ratio are more precise to determine overweight or obese. Objective To determine the usefulness of waist circumference and waist-hip ratio as hypertensive screening tools for children aged 6-11 years. Methods This analytical study with cross-sectional design and multistage cluster sampling method was conducted in August-September 2017 at a primary school in Bandung, West Java, Indonesia. Subjects underwent height, weight, waist circumference, hip circumference, and blood pressure measurements. Receiver operating characteristic (ROC) curve analysis was done to obtain the area under curve (AUC), cut-off point, sensitivity, specificity, and prevalence ratio. Results Subjects were 325 children consisting of 187 males and 138 females. Hypertension was diagnosed in 47 children (37 males and 10 females). Mean waist circumference and waist-hip circumference ratio were significantly higher in the hypertensive group than in the normotensive group. The hypertensive group had a mean waist circumference of 72.6 (SD 12.8) cm, AUC 0.779 (95%CI 0.730 to 0.823; P<0.001), cut-off point >65 cm, sensitivity 66.0%, specificity 76.3%, and prevalence ratio 4.55. This group had mean waist-hip ratio of 0.94 (SD 0.10), AUC 0.724 (95%CI 0.672 to 0.772; P<0.001), waist-hip ratio cut-off >0.91, sensitivity 59.6%, specificity 77.0%, and prevalence ratio 3.73. Conclusion Waist circumference >65 cm or waist-hip ratio >0.91 can be used to screen for hypertension in children aged 6-11 years with negative predictive values of 92.0% and 91.8%, respectively.  

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