scholarly journals CLINICAL IMPORTANCE OF DEFINITION OF SINGLE NUCLEOTIC POLYMORPHISMS IN PATIENTS WITH BREAST CANCER (LITERATURE REVIEW)

THE BULLETIN ◽  
2019 ◽  
Vol 5 (381) ◽  
pp. 169-174
Author(s):  
V. V. Benberin ◽  
◽  
N. A. Shanazarov ◽  
N. K. Seidalin ◽  
N. Y. Lisovska ◽  
...  
2018 ◽  
Vol 16 (2) ◽  
Author(s):  
Amanda Alves da Silva ◽  
Juliane Carlotto ◽  
Inajara Rotta

ABSTRACT The definition of antineoplastic administration sequences can help planning of therapeutic regimens in a more rational way, and thus optimize chemotherapy effects on patients, increasing efficacy and reducing toxic effects. In this way, this study aimed to evaluate the infusion order of antineoplastic agents of the main therapeutic protocols used in the treatment of colorectal and breast cancer which are used in a tertiary hospital, identifying possible interactions dependent on the infusion sequence. For the definition of protocols adopted in the hospital, medical prescriptions were used in the period of January to March 2016 and a literature review was conducted to search for studies assessing the sequence of administering the selected regimens. The databases used were SciELO, LILACS and MEDLINE, in addition to Micromedex Solutions® and UpToDate®. A total of 19 protocols were identified for antineoplastic therapy, 11 for colorectal cancer and 8 for breast cancer. The selected articles provided evidence for administration order of 19 protocols, and three protocols did no report relevance of infusion sequence. Sequence-dependent interactions were mainly related to toxicity, pharmacokinetics and efficacy of the drug combination. The definition of the infusion sequence has a great impact on the optimization of therapy, increasing efficacy and safety of the protocols containing combined antineoplastic therapies.


Author(s):  
Aline Silva Coelho ◽  
Marielle Anália da Silva Santos ◽  
Rosecleide Inácio Caetano ◽  
Camila Fátima Piovesan ◽  
Larissa Aparecida Fiuza ◽  
...  

2021 ◽  
pp. 088541222199424
Author(s):  
Mauro Francini ◽  
Lucia Chieffallo ◽  
Annunziata Palermo ◽  
Maria Francesca Viapiana

This work aims to reorganize theoretical and empirical research on smart mobility through the systematic literature review approach. The research goal is to reach an extended and shared definition of smart mobility using the cluster analysis. The article provides a summary of the state of the art that can have broader impacts in determining new angles for approaching research. In particular, the results will be a reference for future quantitative developments for the authors who are working on the construction of a territorial measurement model of the smartness degree, helping them in identifying performance indicators consistent with the definition proposed.


2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Walid Sasi ◽  
Dibyesh Banerjee ◽  
Kefah Mokbel ◽  
Anup K. Sharma

Adenoma or florid papillomatosis of the nipple (FPN) is a rare benign disease which has histopathological features similar to those of a mammary papillary carcinoma. Here, we report a rare case of bilateral florid papillomatosis of the nipple and breast cancer, with a literature review.


2021 ◽  
pp. 154041532199062
Author(s):  
Elizabeth A. Anderson ◽  
Jane M. Armer

Introduction: Breast cancer-related lymphedema (BCRL) is a treatment sequela with negative physical and psychological implications. BCRL is a lifetime concern for survivors and is currently incurable. With the increase in the Latino population in the United States, it is critical for the cancer care community to address factors that increase BCRL risk and negatively impact long-term quality of life. This literature review undertook to identify successful intervention strategies for BCRL among Latina survivors. Methods: Multiple databases were searched for published articles from 2006 to 2020. PRISMA guidelines were utilized. Data were extracted related to physical activity, diet, and psychosocial stress concerns of Latinas at risk for or living with BCRL. Results: Eleven interventions combined education and skill-building techniques to address physical activity, diet, and stress management for BCRL. Family involvement, peer-mentoring, culturally tailored education, and self-care skill development were identified as important for Latina survivors. Conclusion: Latina survivors may benefit from culturally tailored BCRL education programs and self-management interventions. Health care professionals and researchers should consider cultural influences when developing clinical intervention strategies to enhance outcomes for Latinas at risk for living with BCRL. In addition, including family members and/or peers in such strategies may be helpful to Latina survivors.


2015 ◽  
Vol 18 (7) ◽  
pp. A461
Author(s):  
J Lachaine ◽  
V Lambert-Obry ◽  
M. M Lemay

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