scholarly journals Epitheloid Hemangioendothelioma of the Submandibular Region

2015 ◽  
Vol 30 (1) ◽  
pp. 47-50
Author(s):  
Peter Ranjit ◽  
Parekh Nayan Madhusudan ◽  
Dayangku Norsuhazenah Pengiran Suhaili ◽  
Ian Christopher Bickle
Keyword(s):  
Local Excision ◽  
Wide Local Excision ◽  
Soft Tissues ◽  
Regional Lymph Node ◽  
Arterial Embolization ◽  
Distant Metastases ◽  
Vascular Tumor ◽  
High Rate ◽  
Histopathological Diagnosis ◽  
Submandibular Region

Objective: To present an uncommon cause for a submandibular mass and review of the literature. Methods: Design: Case Report Setting: Tertiary Government Hospital Patient: One Results: A 25-year-old lady presented with a painless chronic submandibular swelling. Ultrasound identified a solid mass, following which an uncomplicated core biopsy was performed obtaining an accurate pre-operative histopathological diagnosis. Pre-operative arterial embolization of this vascular mass led to a relatively bloodless wide local excision. Radiological imaging for distant metastases was negative. Conclusion: Epitheloid Hemangioendothelioma is an uncommon cause for a submandibular mass. A malignant vascular soft tissue tumor with morphologic characteristics similar to carcinomas, melanomas and epitheloid sarcomas, it has a high rate of metastasis and morbidity when it affects the soft tissues and viscera. Immunohistochemistry provides clues to differentiation, and recommended treatment consists of a surgical wide local excision with regional lymph node resection. As there are no established standard therapeutic protocols for this disease due to its rarity, an individual case-by-case approach and follow-up needs to be undertaken. Keywords:  epitheloid hemangioendothelioma, malignant vascular tumor, submandibular mass

scholarly journals Management of pseudo tumour in haemophilia patients

2020 ◽  
Vol 7 (6) ◽  
pp. 2033
Author(s):  
Sherlyn Ambrose ◽  
Giridhar Ashwath ◽  
Sreekar Balasundaram ◽  
Suresh Kumar ◽  
Cecil Ross ◽  
...  
Keyword(s):  
Male Patient ◽  
Soft Tissues ◽  
Hemophilia A ◽  
Rare Complication ◽  
Arterial Embolization ◽  
Surgical Excision ◽  
High Rate ◽  
Treatment Modalities ◽  
Fistula Formation ◽  
Slow Growing

A hemophilic pseudotumor is one of the rare complications of hemophilia that results from repetitive bleeding, forming an expanding destructive encapsulated hematoma and necrosed tissue. It has a considerable amount of morbidity. These have become rare over the years with better treatment modalities like factor replacement. Presently, excision is the preferred treatment by many authors. There are instances where surgical excision is not feasible. In such situations, radiotherapy and arterial embolization should be considered either alone or as an adjunct to surgery. A 32 years old male patient, with severe hemophilia A diagnosed with an abdominal tumour 7 years ago during routine screening, that progressively grew to encompass the lower abdominal area. A 44 years old male patient with hemophilia A presented with slow growing swelling over the left gluteal region since, 10 years associated with ulceration and bleeding since, 3 days. The management of a patient with a haemophilic pseudo tumour is complex, with a high rate of potential complications. Surgical excision is the treatment of choice but can only be carried out by a multidisciplinary surgical team. The main postoperative complications are rebleed, infection, fistula and pathological fractures. Pelvic pseudo tumours can even become complicated by fistula formation to the large bowel and by obstruction of the ureters. Untreated pseudo tumours will ultimately destroy soft tissues, erode bone, and may produce neurovascular complications. The hemophilic pseudo tumour is a rare entity which is slow growing painless tumour, with few reports worldwide in the management of this rare complication.

scholarly journals “Deep” vertical Mohs and closure with a tumor-free flap for dermatofibrosarcoma protuberans: A case report

2019 ◽  
Vol 7 ◽  
pp. 2050313X1984778
Author(s):  
Ann M John ◽  
Gina Francisco ◽  
Radhika Srivastava ◽  
Hamza Bhatti ◽  
Babar K Rao
Keyword(s):  
Case Report ◽  
Local Recurrence ◽  
Surgical Technique ◽  
Local Excision ◽  
Free Flap ◽  
Malignant Tumor ◽  
Wide Local Excision ◽  
Dermatofibrosarcoma Protuberans ◽  
High Rate ◽  
Low Grade

Dermatofibrosarcoma protuberans is an uncommon low-grade malignant tumor that can invade locally and rarely metastasize. Dermatofibrosarcoma protuberans has a high rate of local recurrence due to incomplete excision, especially in deep tissues. Morbidity is often related to multiple local recurrences and removal of excessive tissue with large, complex repairs. We present a case of incompletely excised dermatofibrosarcoma protuberans after initial wide local excision. We subsequently employed a “deep” vertical Mohs micrographic surgical technique to remove the remaining tumor while creating a flap with the tumor-free superficial portion to preserve tissue and avoid a complicated repair. The patient is tumor-free for 7 years.

scholarly journals The management of non-melanocytic skin malignancies of the scalp and calvarium

2014 ◽  
Vol 47 (01) ◽  
pp. 36-42 ◽  
Author(s):  
Harun Çöloğlu ◽  
Burak Özkan ◽  
Mesut Şener ◽  
Ahmet Çağri Uysal ◽  
Hüseyin Borman
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Squamous Cell ◽  
Wide Local Excision ◽  
Locally Advanced ◽  
Histopathological Diagnosis ◽  
Full Thickness ◽  
Adjacent Structures

ABSTRACT Background: The management of advanced cutaneous malignancies has been controversial. Thirteen patients with nonmelanoma skin neoplasias that had invaded the bone of the calvarium and scalp were treated in our centre. Objective: The purpose of this study was to evaluate our experience in treating these malignancies with scalp resection and full or partial thickness cranium reconstruction. Patients and Methods: From June 2008 to March 2012, thirteen patients with locally advanced tumours of the scalp invading the calvarium were treated with wide local excision of the scalp combined with an underlying craniectomy and dural resection if needed. Results: Using histopathological diagnosis eleven patients were diagnosed with basal cell carcinoma and two patients with squamous cell carcinoma. A full thickness cranium resection was performed in seven patients and partial in six patients. Conclusion: These large cancers occasionally invade adjacent structures, as well as bone, presenting a challenging surgical problem. In general, giant rotational or island scalp flaps and free tissue transfers are needed to close the area. Finding clean margins are an important part of treating patients with bone involvement and can usually be attained using outer tabula curettage thus preventing unnecessary morbidity.

scholarly journals Focal, Extranodal Primary Polymorph Hemangioendothelioma Treated With Endovascular Embolization Plus Open Surgery Resection: Rare Case Report and Review

2021 ◽  
Author(s):  
Esteban Ramirez-Ferrer ◽  
Francisco Javier Perez-Pinto ◽  
William Mauricio Riveros-Castilla ◽  
Samuel David Morales-Naranjo ◽  
Luis Alejandro Osorio-Bohorquez
Keyword(s):  
Case Report ◽  
Open Surgery ◽  
Rare Case ◽  
Tumor Resection ◽  
Vascular Tumor ◽  
Endovascular Embolization ◽  
High Rate ◽  
Endovascular Coiling ◽  
Histopathological Diagnosis ◽  
Surgery Resection

Abstract Background: We report the rare case of an adult with a primary extranodal polymorphous hemangioendothelioma at dorsum, treated with endovascular coiling followed by open surgery resection. Clinical history, findings of spinal arteriography, histopathological findings and combined surgical procedure are reported.Case report: A 22-year-old male patient complained of a dorsal mass that has been increasing in size, painful, soft, no mobile and without neurological symptoms. A vascular tumor was suspected and an endovascular followed by an open surgical approach was performed. Histopathological diagnosis of an extranodal polymorph hemangioendothelioma was documented and a total resection was confirmed by free-tumor resection margin. The postoperative course was uneventful. Conclusion: Polymorph hemangioendothelioma is a rare vascular tumor. given the high vascular features of the lesion and, therefore, the high rate of bleeding during surgery.

scholarly journals Squamous Cell Carcinoma of Nose: An Unusual Presentation

2011 ◽  
Vol 4 (3) ◽  
pp. 166-167
Author(s):  
Aseem Mishra ◽  
Smita K Nagle ◽  
Vikram Oberoi ◽  
Mohan Vasant Jagade ◽  
Vimal Kasbekar
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Human Papilloma Virus ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Squamous Cell ◽  
Wide Local Excision ◽  
Histopathological Diagnosis ◽  
Papilloma Virus ◽  
Nasal Vestibule

ABSTRACT Most commonly, a carcinoma of nose is a basal cell carcinoma and a squamous cell carcinoma commonly arise from the dorsum of the nose. We present here a case of 35-year-old female with a squamous cell carcinoma of the nasal vestibule, which started as a wart and was very slowly progressive, until it was excised by a practitioner in a village. It then progressed rapidly and presented to us. The mass appeared a squamous cell carcinoma arising from nasal vestibule. The wart-like presentation also associates the etiology of squamous cell carcinoma to human papilloma virus and the disadvantages of excision of mass without proper histopathological diagnosis. The case was successfully managed with wide local excision with reconstruction by buccal and Estlander's flap.

Vulvar melanoma: A monocentric retrospective study on 29 cases.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e19036-e19036
Author(s):  
Giulio Tosti ◽  
Edoardo Botteri ◽  
Giuseppe Spadola ◽  
Federica Baldini ◽  
Massimo Mosconi ◽  
...  
Keyword(s):  
Overall Survival ◽  
Retrospective Study ◽  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Local Excision ◽  
Wide Local Excision ◽  
Distant Metastases ◽  
Node Biopsy ◽  
Vulvar Melanoma

e19036 Background: Vulvar melanoma (VM) represents 3-7% of melanoma in women. The 5-year survival rate ranges from 8 to 55%. Surgical excision represents the best definitive therapy but surgical radicality does not impact on recurrence or survival. Methods: Thirty women with histologically confirmed VM diagnosed between 1993 and 2009 were selected for this monocentric retrospective study. One patient with metastases at time of diagnosis was excluded from the statistical analysis. Clinical, pathological and follow-up data were collected. Cumulative incidences of events were calculated and compared across subgroups by means of the Gray test. Results: Average age at diagnosis was 62 years. Average Breslow thickness was 4.91 mm. Ulceration was present in 11 cases and was unknown in 5. One case of VM was multifocal at presentation. Eleven patients underwent a wide local excision, 11 a hemivulvectomy and 7 a radical vulvectomy Sentinel node biopsy was performed in 23 patients and at least one positive sentinel node was found in 8 cases. Eight patients received adjuvant therapy. Ten patients had a second tumor (other than melanoma); of these, a breast cancer was recorded in 5 cases. Four patients had a second primary melanoma: of the vulva (n=2), vagina (n=1), and urethra (n=1). Median follow-up among ongoing survivors was 79 months and median overall survival was 69 months. The 5-year overall survival was 55.4%. Median event free survival 34 months. Positive lymph nodal status was associated with an increased risk of loco-regional recurrences (P=0.04). Positive lymph nodal status (P=0.06), Breslow thickness > 2mm (P=0.05) and number of mitoses > 10/mm2 (P=0.04) increased the risk of distant metastases. Age, ulceration and type of surgery were not significantly associated with any type of event. Conclusions: Lymph node involvement, elevated depth of invasion and a high number of mitoses were the most important prognostic factors for locoregional recurrence and distant metastases. The same trends were observed for the overall survival, but results were not statistically significant. Conservative surgery in the form of wide local excision with adequate margins may replace vulvectomy. Sentinel node biopsy is feasible and its role in VM should be further investigated.

Small Neuroendocrine Tumors of the Whole Gastrointestinal Tract Performed Endoscopic or Surgical Resections Also Show Positive for Lymphovascular Invasion

Digestion ◽  
2021 ◽  
pp. 1-8
Author(s):  
Haruna Miyashita ◽  
Takuji Yamasaki ◽  
Yoshihiro Akita ◽  
Yoshitaka Ando ◽  
Yuki Maruyama ◽  
...  
Keyword(s):  
Surgical Resection ◽  
Neuroendocrine Tumors ◽  
Tumor Size ◽  
Lymphovascular Invasion ◽  
Distant Metastases ◽  
High Rate ◽  
Ki 67 ◽  
Primary Endpoints ◽  
Invasion Impact ◽  
Prognostic Stratification

<b><i>Background and Aims:</i></b> In gastrointestinal neuroendocrine tumors (GI-NETs), tumor size and grading based on cellular proliferative ability indicate biological malignancy but not necessarily clinically efficient prognostic stratification. We analyzed tumor size- and grading-based prevalence of lymphovascular invasion in GI-NETs to establish whether these are true biological malignancy indicators. <b><i>Methods:</i></b> We included 155 cases (165 lesions), diagnosed histologically with GI-NETs, that had undergone endoscopic or surgical resection. Patient age, sex, method of treatment, tumor size, invasion depth, lymphovascular invasion positivity according to Ki-67 index-based neuroendocrine tumor grading, distant metastases, and outcome were evaluated. The primary endpoints were the prevalence of lymphovascular invasion according to tumor size and grading. <b><i>Results:</i></b> Overall, 24.8% were positive for lymphovascular invasion. There was a high rate of lymphovascular invasion positivity even among grade 1 cases (22.8%). The rate of lymphovascular invasion was 3.4% for grade 1 cases &#x3c;5 mm, with a lymphovascular invasion rate of 8.7% for those 5–10 mm. Lymphovascular invasion ≤10% required a tumor size ≤8 mm, and lymphovascular invasion ≤5% required a tumor size ≤6 mm. A cutoff of 6 mm was identified, which yielded a sensitivity of 79% and a specificity of 63%. Even small GI-NETs grade 1 of the whole GI tract also showed positive for lymphovascular invasion. <b><i>Conclusions:</i></b> GI-NETs ≤10 mm had a lymphovascular invasion prevalence exceeding 10%. The lymphovascular invasion impact in GI-NET development is incompletely understood, but careful follow-up, including consideration of additional surgical resection, is crucial in cases with lymphovascular invasion.

Sign in / Sign up

Export Citation Format

Share Document