scholarly journals Correlation Between Predialysis Systolic Blood Pressure and Predialysis Hydration Status in Hemodialysis Patients

2018 ◽  
Vol 3 (4) ◽  
pp. 1025-1030
Author(s):  
Magdalena Castro ◽  
Rodrigo Orozco ◽  
Pedro Figueroa ◽  
Cristina Hertz ◽  
Victoria Aspillaga

One of the goals of hemodialysis is to maintain normal hydration status in ESRD patients. Pre hemodialysis systolic blood pressure is usually used as a clinical parameter of hydration status and to set ultrafiltration rate before Hd. It is unclear how much pre-Hd SBP correlated with hydration status. The aim was to determine correlation between pre-Hd SBP and hydration status before Hd. An observational correlation study was performed in two dialysis centers in Santiago, Chile, from January-June, 2011. Adult patients in Hd for at least three months, who gave their informed consent were included. Patients with pacemaker, amputee, hospitalized and metallic prostheses were excluded. Total-body water and overhydrated were assessed with bioimpedance spectroscopy before the first and third dialysis session of the week. Pre-Hd SBP, pre-Hd body weight, pre-Hd TBW and pre-Hd OH, were analyzed using Pearson correlation and linear regression model. 96 measurements were assessed, 52 % were male with median age 59.5 years. The correlation between pre-Hd SBP and pre-Hd overhydration was r=0.33, and total body water r=0.15, with a predicted value, R2=0.10 and R2 =0.14 respectively. Pre-Hd SBP had low correlation with pre-Hd hydration status and by itself, is not a reliable parameter to set ultrafiltration rate before Hd. Nevertheless Pre-Hd body weight predicted in 70 % the pre-Hd TBW.

2017 ◽  
Vol 13 (1) ◽  
pp. 155014771668509 ◽  
Author(s):  
Wei-Ling Chen ◽  
Chung-Dann Kan ◽  
Chia-Hung Lin ◽  
Ying-Shin Chen ◽  
Yi-Chen Mai

Maintaining adequate dry weight and fluid volume balance is an important issue for dialysis patients. Malnutrition and sodium intake are the primary factors that cause fluid volume imbalance and changes in body weights. Inadequate dry weight control results in higher levels of blood pressures and is related to various complications, such as volume overload, hypertension, congestive symptoms, and cardiovascular diseases. Moreover, inadequate fluid removal provokes hypotension during dialysis treatment. Thus, we propose an early warning tool based on fuzzy color reason analysis in predialysis healthcare for hypervolemia screening. The anthropometric method is a rapid, non-invasive, and simple technique for estimating the total body water. In this study, Watson standard formula is employed to estimate cross-sectional standard of total body water with the patient characteristics, including gender, age, height, and weight. In contrast to the experienced anthropometric formulas, Watson formula has less than 2% of margin errors and provides a criterion as a reference manner to estimate the total body water in patient’s normal dry weight. In addition, inadequate dry weight and total body water controls will lead to higher blood pressures. The systolic blood pressure is also an indicator to evaluate pre-hypertension of 120–139 mmHg and hypertension of greater than or equal to 140 mmHg. Therefore, the levels of two indicators, total body water and systolic blood pressure, are parameterized with fuzzy membership grades to describe the normal and the specific ranges of undervolemia and hypervolemia. A color reason analysis utilizes a hue–saturation–value color model to design a color perceptual manner for separating normal condition from hypervolemia or undervolemia. Normalized hue angle and saturation value provide a promising visual representation with color codes to realize the patients’ diagnosis. Dialysis patients with hypertension demonstrated that the proposed model can be used in clinical applications. In addition, a healthcare chair is carried out to measure blood pressure and weight in predialysis. The proposed assistant tool integrates an electronic pressure monitor and an electronic weight monitor, and fuzzy color reason analysis is also intended to be established in an intelligent vehicle via a WiFi wireless local area network for cloud computing.


Author(s):  
Aaron R. Caldwell ◽  
Megan E. Rosa-Caldwell ◽  
Carson Keeter ◽  
Evan C. Johnson ◽  
François Péronnet ◽  
...  

<b><i>Background:</i></b> Debate continues over whether or not individuals with low total water intake (TWI) are in a chronic fluid deficit (i.e., low total body water) [<xref ref-type="bibr" rid="ref1">1</xref>]. When women with habitually low TWI (1.6 ± 0.5 L/day) increased their fluid intake (3.5 ± 0.1 L/day) for 4 days 24-h urine osmolality decreased, but there was no change in body weight, a proxy for total body water (TBW) [<xref ref-type="bibr" rid="ref2">2</xref>]. In a small (<i>n</i> = 5) study of adult men, there were no observable changes in TBW, as measured by bioelectrical impedance, after increasing TWI for 4 weeks [<xref ref-type="bibr" rid="ref3">3</xref>]. However, body weight increased and salivary osmolality decreased indicating that the study may have been underpowered to detect changes in TBW. Further, no studies to date have measured changes in blood volume (BV) when TWI is increased. <b><i>Objectives:</i></b> Therefore, the purpose of this study was to identify individuals with habitually low fluid intake and determine if increasing TWI, for 14 days, resulted in changes in TBW or BV. <b><i>Methods:</i></b> In order to identify individuals with low TWI, 889 healthy adults were screened. Participants with a self-reported TWI less than 1.8 L/day (men) or 1.2 L/day (women), and a 24-h urine osmolality greater than 800 mOsm were included in the intervention phase of the study. For the intervention phase, 15 participants were assigned to the experimental group and 8 participants were assigned to the control group. The intervention period lasted for 14 days and consisted of 2 visits to our laboratory: one before the intervention (baseline) and 14 days into the intervention (14-day follow-up). At these visits, BV was measured using a CO-rebreathe procedure and deuterium oxide (D<sub>2</sub>O) was administered to measure TBW. Urine samples were collected immediately prior, and 3–8 h after the D<sub>2</sub>O dose to allow for equilibration. Prior to each visit, participants collected 24-h urine to measure 24-h hydration status. After the baseline visit, the experimental group increased their TWI to 3.7 L for males and 2.7 L for females in order to meet the current Institute of Medicine recommendations for TWI. <b><i>Results:</i></b> Twenty-four-hour urine osmolality decreased (−438.7 ± 362.1 mOsm; <i>p</i> &#x3c; 0.001) and urine volume increased (1,526 ± 869 mL; <i>p</i> &#x3c; 0.001) in the experimental group from baseline, while there were no differences in osmolality (−74.7 ± 572 mOsm; <i>p</i> = 0.45), or urine volume (−32 ± 1,376 mL; <i>p</i> = 0.89) in the control group. However, there were no changes in BV (Fig. <xref ref-type="fig" rid="f01">1</xref>a) or changes in TBW (Fig. <xref ref-type="fig" rid="f01">1</xref>b) in either group. <b><i>Conclusions:</i></b> Increasing fluid intake in individuals with habitually low TWI increases 24-h urine volume and decreases urine osmolality but does not result in changes in TBW or BV. These findings are in agreement with previous work indicating that TWI interventions lasting 3 days [<xref ref-type="bibr" rid="ref2">2</xref>] to 4 weeks [<xref ref-type="bibr" rid="ref3">3</xref>] do not result in changes in TBW. Current evidence would suggest that the benefits of increasing TWI are not related changes in TBW.


1969 ◽  
Vol 72 (1) ◽  
pp. 31-40 ◽  
Author(s):  
W. R. McManus ◽  
R. K. Prichard ◽  
Carolyn Baker ◽  
M. V. Petruchenia

SUMMARYThe use of tritiated water to estimate total body-water content of animals experiencing recovery from under-nutrition was studied.The time for equilibration of tritiated water (TOH), given intraperitoneally, with total body water (TBW) was determined in rabbits and in rats. As judged by the specific activity of blood water, equilibration had occurred by 76–125 min in the rabbit and did not appear to be affected by the plane of nutrition. However, between slaughter groups the specific activity of water obtained from the liver 180 min after injection of TOH was significantly different from the specific activity of water simultaneously obtained from the blood plasma. It is concluded that the liver is not a suitable tissue to use for testing achievement of equilibration.As judged by the specific activity of blood water compared to that of water from the whole body macerate, equilibration in mature rats either in stable body condition or undergoing rapid compensatory growth occurred in less than 60 min.A trial comparing TOH-space (corrected by 3% body weight) and actual TBW (by desiccation) was conducted on thirty rabbits which experienced under-nutrition followed by compensatory growth.Prior to under-nutrition the agreement between actual and estimated TBW was satisfactory and within 2·3%. During compensatory growth the agreement was poor— the TOH values over-estimating actual TBW by about 12%.A trial with mature rats confirmed the findings with rabbits. For rats in stable body weight the mean estimated TOH-space for fourteen animals was within 1·2% of the actual TBW. For fourteen rats undergoing compensatory growth the mean estimated TOH-space (corrected by 3% body weight) overestimated actual TBW by 6·2%.


Nutrients ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 565 ◽  
Author(s):  
Ana Isabel Laja García ◽  
Maria de Lourdes Samaniego-Vaesken ◽  
Teresa Partearroyo ◽  
Gregorio Varela-Moreiras

The achievement of adequate hydration status is essential for mental and physical performance and for health in general, especially in children and adolescents. Nevertheless, little is known about hydration status of this population, mainly due to the limited availability of research tools; thus, the objective of the current study was to adapt and validate our hydration status questionnaire in a Spanish adolescent-young population. The questionnaire was validated against important hydration markers: urine colour, urine specific gravity, haemoglobin, haematocrit and total body water and involved 128 subjects aged between 12–17 years. Water intake was also estimated through a three-day dietary record and physical activity was assessed through accelerometers. Participants completed the questionnaire twice. Water balance and water intake were correlated with urine specific gravity and with total body water content. Water intake obtained by the questionnaire was correlated with results from the three-day dietary record. The intraclass correlation coefficient indicated moderate concordance between both recordings and the Cronbach’s alpha revealed high consistency. The Bland and Altman method indicated that the limits of agreement were acceptable to reveal the reliability of the estimated measures. In conclusion, this is the first time that a questionnaire is valid and reliable to estimate hydration status of adolescent-young populations.


2004 ◽  
Vol 22 (Suppl. 1) ◽  
pp. S193
Author(s):  
Marcospaulo Milagres ◽  
Caciane Souza ◽  
Clarissa Carvalho ◽  
Claudio Amaral ◽  
Cynthia Soares ◽  
...  

1988 ◽  
Vol 47 (3) ◽  
pp. 435-445 ◽  
Author(s):  
F. R. Dunshea ◽  
A. W. Bell ◽  
K. D. Chandler ◽  
T. E. Trigg

ABSTRACTA two-pool model of tritiated water kinetics was investigated as a means of partitioning total body water into empty body water and gut water in 17 lactating goats. Empty body water, gut water and total body water were of a similar magnitude to, and highly correlated with, a rapidly equilibrating tritiated water pool, a more slowly equilibrating pool and the sum of these two pools, respectively.Empty body fat was poorly correlated with both live weight and empty body weight (R2 = 0·42 and 0·51, respectively). However, there was a strong inverse relationship between the water and fat contents of the empty body. Consequently, empty body fat was accurately predicted by a multiple regression equation which included both empty body weight and empty body water as independent variables (R2 = 0·97). Substitution of these variables with estimates derived from tritiated water kinetics still resulted in a high correlation (R2 = 0·88). Tritiated water kinetics offered little improvement over live weight alone in the prediction of empty body protein, empty body ash or fat-free empty body.


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1169-1169
Author(s):  
Jacob Gray ◽  
Tay Kennedy

Abstract Objectives Phase angle, derived from bioelectrical impedance analysis (BIA), is used to describe both cellular and overall health. Many of the variables measured using BIA vary based on the hydration status of the individual. The ratio between extracellular water/total body water is commonly measured in BIA, and can be used as a measure of individual hydration. This pilot study explores the relationship between individual hydration status and phase angle and other BIA measurements. Methods Male college students (n = 57) from Oklahoma State University-Stillwater were recruited through an email messaging campaign. The participants answered an online Qualtrics demographic survey; height (±0.1 cm), blood pressure, and weight were taken. The Seca Medical Body Composition Analyzer mBCA 514 was used to conduct the BIA. Variable mean, standard deviations, and frequencies were calculated using SPSS version 25. Pearson correlation analysis and regression analysis were conducted. Significance was set at &lt;.05. Results Participants characteristics included: age (m = 21.7 ± 1.3 years), 54% BMI &lt;25, 39% blood pressure &lt;120/80, and 63% white/7% Native American. Mean % body fat was 20.28 ± 8.76, and skeletal muscle was 32.223 kg ± 4.432 and visceral fat was 2.01 liters ± 2.11.Phase angle percentile ranged from 1% to 99% (m = 62.0% ± 31.4) and extracellular water/total body water ratio (ECW/TBW) ranged from 35.7 to 41.6 (m = 39.32 ± 1.35). Phase angle percentile was positively correlated with skeletal muscle mass (r = 0.503, P = 0.000) and negatively correlated with ECW/TBW (r = −0.659, P = 0.000), but not with other BIA variables. These two variables significantly predicted phase angle percentile (r2 = 0.817, P = 0.000). The standardized β was −0.762 (P = 0.000) for ECW/TBW and 0.627 (P = 0.000) for skeletal muscle mass. Conclusions The association of ECW/TBW on phase angle percentile suggest further investigation of the impact of water on this indicator of health is warranted. An investigation with a method of modulating ECW/TBW would be a logical next step in understanding this relationship. Funding Sources Funding was provided by the Lew Wentz Foundation, and the Nutritional Sciences Department at Oklahoma State University.


PEDIATRICS ◽  
1951 ◽  
Vol 7 (3) ◽  
pp. 321-327 ◽  
Author(s):  
BENT J. FRIIS-HANSEN ◽  
MALCOLM HOLIDAY ◽  
THOMAS STAPLETON ◽  
WILLIAM M. WALLACE

Total body water was determined in 24 normal infants and children by deuterium oxide dilution and by the antipyrine method. A micro-modification of the antipyrine method is described. Agreement between the two methods for determining total body water was good. Total body water was found to be highest in premature and newborn babies, the values ranging from 70 to 83% of body weight. During the first 6 months of life there was a gradual decrease of body water as per cent body weight. From 6 months to 11 years of age, the values varied between 53 and 63% with no correlation to age or sex.


1974 ◽  
Vol 82 (1) ◽  
pp. 105-112 ◽  
Author(s):  
B. S. W. Smith ◽  
A. R. Sykes

SUMMARYEight mature female sheep were offered a ration which maintained body weight constant during a 20-week period. During the final 10 weeks a comparison was made in each animal of the pattern of equilibration and urinary losses of tritiated water during 8 h after dosing by four different routes. These were intravenous, intraperitoneal, intraruminal and a combination of the intraperitoneal and intraruminal routes. Tritiated water spaces were calculated from (a) the 8-h plasma specific activity and (b) by extrapolation to zero time of the plasma specific activities during the 7 days after injection. At the end of the experiment the fat and water contents of the bodies of the sheep were determined directly.Complete equilibration of tritiated water between plasma and rumen water was not achieved in all animals 8 h after intravenous or intraperitoneal injection but was when the rumen was primed by the combination of intraperitoneal and intraruminal dosing. After intraruminal dosing equilibration was not achieved in any animal within 8 h of dosing.Urinary losses of marker were lower after intraruminal dosing but otherwise averaged 4–5 % of the dose/1 urine. This was equivalent to 0·3–6·7% of the dose for individual sheep.Errors resulting from incomplete equilibration and urinary loss of marker did not influence the efficiency of prediction of total body water from tritiated water space. The multiple correlation coefficient relating body fat with empty body weight and its water content was very high (r = 0·99). Errors introduced into this relationship by the inclusion of gut water in the prediction equations were apparently of a similar magnitude to those resulting from the errors in the estimation of tritiated water space.The extrapolation method for the determination of tritiated water space was shown to have the same accuracy as equilibration techniques under these controlled dietary conditions.


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