scholarly journals REVASCULARISATION OF AN IMMATURE PERMANENT TOOTH USING PLATELET RICH FIBRIN AND BIODENTIN AS A MATRIX - A CASE REPORT

2019 ◽  
Vol 3 (7) ◽  
Author(s):  
Dr. Anil K Tomer ◽  
Dr. Panna Mangat ◽  
Dr. Akankshita Behera ◽  
Dr. Savneet Kour ◽  
Dr. Artika Gupta ◽  
...  
Keyword(s):  
Ethylenediaminetetraacetic Acid ◽  
Treatment Options ◽  
Permanent Tooth ◽  
Permanent Teeth ◽  
Periapical Lesion ◽  
Platelet Rich Fibrin ◽  
Growth Status ◽  
Triple Antibiotic Paste ◽  
Regenerative Approach ◽  
Dentin Formation

Any injury to the pulp during its development lead to cessation of dentin formation and root growth. Status of the pulp and root development are the decisive factors in the treatment approach. Various treatment options include surgery with rood end sealing,  apexification using calcium hydroxide ,placement of apical plug and regenerative endodontic procedures to induce apexogenesis. This study describes the treatment of an immature permanent tooth which was treated with regenerative approach using 3% NaOCl and 17%  ethylenediaminetetraacetic acid as irrigants,and then medicated with triple antibiotic paste, after that platelet rich fibrin (PRF) and Biodentine were place in the canal. On follow up at 3 ,6,12 months healing of periapical lesion, dentinal thickening, and apical closure were evident. So, PRF can be used for the treatment of immature permanent teeth with periapical lesion, as part of a regenerative endodontic procedures. Keywords: Platelet rich fibrin (PRF), Biodentine, open apex, revascularisation

scholarly journals Prospective cohort study of regenerative potential of non vital immature permanent maxillary central incisors using platelet rich fibrin scaffold

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Selvakumar Kritika ◽  
V. Sujatha ◽  
N. Srinivasan ◽  
Senthil Kumar Renganathan ◽  
Sekar Mahalaxmi
Keyword(s):  
Gradual Increase ◽  
Mineral Trioxide Aggregate ◽  
Permanent Teeth ◽  
Bonferroni Correction ◽  
Platelet Rich Fibrin ◽  
Triple Antibiotic Paste ◽  
Fibrin Scaffold ◽  
The Mean ◽  
Post Hoc

AbstractRegenerative endodontic procedures have gained momentum as a treatment modality of young immature permanent teeth. Literature reports reveal that platelet-rich fibrin (PRF) stimulates growth factors and induces regeneration. This study was undertaken to assess the regenerative potential of non-vital immature permanent maxillary central incisors using PRF with a follow-up for 2 yrs. 19 patients in the age group of 9–25 yrs with immature, non-vital permanent maxillary central incisors (n = 23) with/without signs and/or symptoms of periapical pathosis and open apex were included in this study. In the first appointment, access opening, canal disinfection and triple antibiotic paste placement were done. In the subsequent visit, PRF was prepared and placed inside the canal. Access was sealed with Mineral trioxide aggregate plug and composite. The patient was reviewed up to 24 mths. The mean difference was statistically analyzed using Friedman test followed by Dunn post hoc test and adjusted by Bonferroni correction (p < 0.05). As per AAE guidelines, the primary and secondary goals were achieved. A significant (p < 0.001) gradual increase in the root length, thickness of dentinal walls and decrease in apical diameter were observed. Within the limitations of this study, PRF placement was clinically and radiographically effective in inducing regeneration of non-vital immature permanent teeth.

Management of necrotic immature permanent maxillary incisors using a modified technique of revascularisation

2021 ◽  
Vol 14 (3) ◽  
pp. e240203
Author(s):  
Arun Mayya ◽  
Shruti Bhandary ◽  
Advith Kolakemar ◽  
Ann Mary George
Keyword(s):  
Platelet Rich Plasma ◽  
Blood Clot ◽  
Treatment Options ◽  
Permanent Teeth ◽  
Treatment Modalities ◽  
Successful Outcome ◽  
Modified Technique ◽  
Platelet Rich Fibrin ◽  
Periapical Lesions ◽  
Over Time

The management of necrotic immature permanent teeth has always been a challenge to endodontists. Various treatment modalities have been tried and tested for achieving a successful outcome. Revascularisation is one among these treatment options, which is gaining widespread attention among endodontists. The growing body of evidence demonstrating the success of revascularisation has led to different variations of this treatment option. Clinicians have over time used different scaffolds such as blood clot, collagen, platelet-rich fibrin (PRF) and platelet-rich plasma for revascularisation. This case report outlines the management of immature maxillary central incisors with pulp necrosis and large periapical lesions in a 19-year-old female patient with a modified technique of revascularisation by combining PRF and blood clot. At the end of 12 months, the patient was completely asymptomatic along with regression of the periapical lesions.

scholarly journals Regenerative Potential of Non-Vital Immature Permanent Maxillary Central Incisors using Platelet Rich Fibrin Scaffold- A Prospective Cohort Study.

2021 ◽  
Author(s):  
Kritika Selvakumar ◽  
Sujatha V ◽  
Srinivasan N ◽  
Senthil Kumar Renganathan ◽  
Sekar Mahalaxmi
Keyword(s):  
Gradual Increase ◽  
Mineral Trioxide Aggregate ◽  
Permanent Teeth ◽  
Bonferroni Correction ◽  
Platelet Rich Fibrin ◽  
Triple Antibiotic Paste ◽  
Fibrin Scaffold ◽  
The Mean ◽  
Post Hoc

Abstract Regenerative endodontic procedures has gained momentum as a treatment modality of young immature permanent teeth. Literature reports reveal that platelet rich fibrin (PRF) stimulates growth factors and induces regeneration. This study was undertaken to assess the regenerative potential of non-vital immature permanent maxillary central incisors using PRF with a follow up for 2yrs. 19 patients in the age group of 9-25yrs with immature, non-vital permanent maxillary central incisors (n=23) with/without signs and/or symptoms of periapical pathosis and open apex were included in this study. In the first appointment, access opening, canal disinfection and triple antibiotic paste placement was done. In the subsequent visit, PRF was prepared and placed inside the canal. Access was sealed with Mineral trioxide aggregate plug and composite. The patient was reviewed upto 24mths. The mean difference was statistically analysed using Friedman test followed by Dunn post hoc test and adjusted by Bonferroni correction (p<0.05). As per AAE guidelines, the primary and secondary goals were achieved. A significant (p<0.001) gradual increase in the root length, thickness of dentinal walls and decrease in apical diameter were observed. Within the limitations of this study, PRF placement was clinically and radiographically effective in inducing regeneration of non-vital immature permanent teeth.

scholarly journals A comparative clinical study of bioceramic and calcium hydroxide based root canal sealer in the treatment of non-vital permanent tooth with periapical lesion

2021 ◽  
Vol 11 (2) ◽  
pp. 26-31
Author(s):  
Farzana Hoque Tanmi ◽  
Md Abdul Hannan Sheikh ◽  
Mozammal Hossain ◽  
SM Abdul Quader ◽  
Salahuddin Ahmed ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Root Canal ◽  
Standard Procedure ◽  
Lesion Size ◽  
Permanent Tooth ◽  
Permanent Teeth ◽  
Periapical Lesion ◽  
Root Canal Sealer ◽  
Anterior Teeth ◽  
Short Period

Introduction: The use of Bioceramic sealer in the obduration of the root canal system has been expected by many of the previous studies. However, the clinical outcome has not yet been established. Objective: To compare the effectiveness of bioceramic and calcium hydroxide based root canal sealer in treatment of non-vital permanent teeth with periapical lesion (Periapical periodontitis). Materials and Methods: A total 100 mature permanent anterior teeth were selected after clinical and radiological examination which had non-vital pulp with periapical lesion. Clinically pulp vitality test, palpation and percussion test was performed maintaining standard procedure. Following cavity preparation and biomechanical preparation, each canal was obturated either with bioceramic (Endosequence BC) or calcium hydroxide based sealer  (Sealapex, Kerr). All participants were evaluated immediately after obturation, at  3 and 6 months for the assessment of change in size of periapical lesion, condition of periodontal ligament space, lamina dura and incidence of post-operative pain, swelling. Statistical analysis was performed using Chi- square(X2) test and t-test. A value of p<0.05 was considered as statistically significant. Results: Bioceramic was more effective in reducing the lesion size than that of calcium hydroxide. At 6 months, the mean lesion size was reduced from 3.52±0.7 to 1.30±0.462 mm in Bioceramics and from 3.48±1.07 to 1.58± 0.498 mm in sealapex treated teeth.. Furthermore, 98% of bioceramic treated teeth and 94% of sealapex treated teeth showed absence of swelling. The differences between two groups were statistically significant (p<0.05). Conclusion: In this short period of study, Bioceramics based sealer seems to be more effective than calcium hydroxide based sealer in repair of periapical lesions of the nonvital teeth. Update Dent. Coll. j: 2021; 11(2): 26-31

scholarly journals Resolution of a large periapical lesion in an immature maxillary lateral incisor with the aid of triple antibiotic paste

2021 ◽  
Vol 76 (09) ◽  
pp. 560-564
Author(s):  
Nicoline Potgieter ◽  
Glynn Buchanan
Keyword(s):  
Root Canal ◽  
Root Formation ◽  
Surgical Intervention ◽  
Lateral Incisor ◽  
Permanent Teeth ◽  
Periapical Lesion ◽  
Periapical Lesions ◽  
Triple Antibiotic Paste ◽  
Maxillary Lateral Incisor ◽  
And Control

Apexification procedures are frequently performed on immature permanent teeth with incomplete root formation, open apices and necrotic pulp status with or without  periapical lesions in order to induce a calcific barrier prior to root canal therapy. The elimination and control of infection in the root canal space is critical to the success of these procedures. A healthy 21-year old male presented with pulpal necrosis, a large periapical lesion, incomplete root formation and an open apex on a maxillary right lateral incisor. Triple antibiotic paste was used to achieve antimicrobial control after traditional calcium hydroxide paste medicament failed to resolve the symptoms. Obturation was achieved using MTA and the conventional apexification technique. Excellent healing of the large periapical lesion was achieved without surgical intervention and the 4-year follow-up CBCT demonstrated complete bone fill of the lesion. Clinicians should be aware that alternative antimicrobial medicaments, such as triple antibiotic paste, may be beneficial in situations where conventional medicaments prove unsuccessful. The use of triple antibiotic paste may result in sufficient healing of the periapical lesion to justify placement of an MTA apical barrier without the need for surgical intervention

Regenerative Endodontic Therapy with Platelet Rich Fibrin: Case Series

2020 ◽  
Vol 44 (1) ◽  
pp. 15-19 ◽  
Author(s):  
G Kandemir Demirci ◽  
P Güneri ◽  
MK Çalışkan
Keyword(s):  
Case Series ◽  
Cone Beam ◽  
Permanent Teeth ◽  
Platelet Rich Fibrin ◽  
Periapical Lesions ◽  
Root Canals ◽  
Immature Teeth ◽  
Triple Antibiotic Paste ◽  
Cone Beam Computerized Tomography

Regenerative endodontic therapy (RET) provides a novel treatment modality for the immature teeth with pulp necrosis. The aim of this case series was to evaluate RET of immature permanent teeth using platelet rich fibrin (PRF) at 36-month follow-up periods. In the present case series, three immature maxillary incisors diagnosed with pulp necrosis and apical periodontitis were treated with RET. The root canals were irrigated with 1.5% sodium hypochlorite (NaOCl) and medicated with triple antibiotic paste(TAP). At the second visit, TAP was removed and root canals were conditioned with 17% EDTA. PRF was used as a scaffold. MTA was placed over PRF and the teeth were restored with composite resin. Periapical radiographs and cone beam computerized tomography(CBCT) were used to evaluate the healing. At the end of the 36-month follow-up periods, there was no response to pulp sensibility tests with cold and electric pulp tester, but all teeth showed decreased periapical lesions or evidence of healing.

scholarly journals Treatment of a Patient with Multiple Impacted Teeth

2007 ◽  
Vol 77 (4) ◽  
pp. 735-741 ◽  
Author(s):  
Richard Scott Conley ◽  
Scott B. Boyd ◽  
Harry L. Legan ◽  
Christopher C. Jernigan ◽  
Craig Starling ◽  
...  
Keyword(s):  
Case Report ◽  
Treatment Planning ◽  
Orthodontic Treatment ◽  
Primary Teeth ◽  
Permanent Tooth ◽  
Permanent Teeth ◽  
Treatment Sequence ◽  
Impacted Teeth ◽  
Case Complexity ◽  
Multiple Primary

Abstract An impacted or missing permanent tooth can add significant complications to an otherwise straightforward case. When multiple impacted teeth are present, the case complexity increases further. Developing a treatment sequence, determining appropriate anchorage, and planning and executing sound biomechanics can be a challenge. The following case report illustrates a patient reportedly diagnosed with mild scleroderma as an adolescent. He presented for orthodontic treatment as an adult with multiple retained primary teeth and multiple impacted teeth. Diagnosis, treatment planning, and various methods of managing guided eruption of impacted teeth will be discussed. Following orthodontic treatment that required extraction of multiple primary and permanent teeth as well as exposure and ligation of multiple permanent teeth by an oral surgeon, the patient finished with a significantly improved functional and esthetic result.

scholarly journals Pulp Revascularization of Immature Permanent Teeth: A Review of the Literature and a Proposal of a New Clinical Protocol

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Mélanie Namour ◽  
Stephanie Theys
Keyword(s):  
Treatment Method ◽  
Permanent Teeth ◽  
Clinical Protocol ◽  
Therapeutic Success ◽  
Immature Teeth ◽  
Triple Antibiotic Paste ◽  
New Treatment ◽  
Near Future ◽  
Pulp Revascularization ◽  
Stimulation Of

Tissue engineering is a growing field. In the near future, it will probably be possible to generate a complete vital tooth from a single stem cell. Pulp revascularization is dependent on the ability of residual pulp and apical and periodontal stem cells to differentiate. These cells have the ability to generate a highly vascularized and a conjunctive rich living tissue. This one is able to colonize the available pulp space. Revascularization is a new treatment method for immature necrotic permanent teeth. Up to now, apexification procedures were applied for these teeth, using calcium dihydroxide or MTA to produce an artificial apical barrier. However, the pulp revascularization allows the stimulation of the apical development and the root maturation of immature teeth. Two pulp revascularization techniques are used in the literature, one using calcium dihydroxide and the second using a triple antibiotic paste. Based on these two different pulp revascularization protocols, which obtain the desired therapeutic success, the literature will be reviewed and analyzed according to the relevance of their choice of materials. Based on the literature, we propose a new relevant protocol and a new mixture of antibiotics.

MINERALIZATION OF TEETH ENAMEL AFTER ERUPTION

2021 ◽  
Vol 74 (6) ◽  
pp. 1297-1301
Author(s):  
Oleksij P. Kostyrenko ◽  
Nataliia I. Vynnyk ◽  
Mykhailo M. Koptev ◽  
Petro A. Hasiuk ◽  
Maksym I. Skrypnyk ◽  
...  
Keyword(s):  
Light And Electron Microscopy ◽  
Permanent Tooth ◽  
Postnatal Period ◽  
Permanent Teeth ◽  
Tooth Crown ◽  
Electron Microscopic ◽  
Cervical Portion ◽  
Immunohistochemical Methods ◽  
Protein Deposit ◽  
Different Parts

The aim: The paper was aimed at the study of the processes of mineralization of the enamel of the permanent tooth after its eruption. Materials and methods: To study the structure of the enamel of permanent teeth has been carried out using light and electron microscopy. The study of the process of the development of the primordia of the permanent teeth involved 10 culled puppies of 30-40 days of age. Microscopic, electron microscopic, immunohistochemical methods of research have been used to study the processes of histogenesis. Results: The studies show that in the postnatal period, the formation of the crown, externally covered with cuticular epithelium, marks the formation of the primordium of the permanent tooth at the follicle stage. After eruption of a tooth, different parts of its crown have three individual structural and functional barriers to enamel biomineralization. The first one is provided by the cuticular epithelium of the pitted areas of the crown, which ensures filtering of the salivary fluid from the protein deposit in the form of a pellicle. The second barrier is defined on the lateral and cuspidate surfaces of the enamel, where the cuticle is erased or poorly expressed. The third structural and functional barrier of enamel biomineralization is located in the cervical portion of teeth of different classes. Conclusions: Different areas of the enamel in the tooth crown have specific filtration barriers, which can be distinguished as follows: pit-and-fissure-and-groove, cuspidateand-approximal, and cervical barriers. The cuticle is poorly expressed or totally absent on the cusps of the tooth crowns in contrast to pitted areas.

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