Assay of Clopidogrel by Using HPLTC Method
2018 ◽
pp. 557-561
Keyword(s):
The present paper describes stability indicating high-performance thin-layer chromatography (HPTLC) assay method for clopidogrel in bulk drugs. The method employed TLC aluminium plates precoated with silica gel 60F-254 as the stationary phase. The solvent system consisted of toluene: methanol: triethylamine (6.5: 4.0: 0.1 v/v/v). The system was found to give compact spot for clopidogrel (<em>R</em><sub>f</sub>value of 0.40 ± 0.010). Densitometric analysis of Clopidogrel was carried out in the absorbance mode at 254 nm. The linear regression analysis data for the calibration plots showed good linear relationship with <em>r</em>2 = 0.888 with respect to peak area in the concentration range 30 - 120 ng/spot.
2020 ◽
Vol 13
(1)
◽
pp. 37-43
2020 ◽
Vol 13
(1)
◽
pp. 054-061
1999 ◽
Vol 82
(4)
◽
pp. 825-829
◽
Keyword(s):
2017 ◽
Vol 9
(9)
◽
pp. 126
1987 ◽
Vol 405
◽
pp. 125-134
◽
1994 ◽
Vol 34
(3)
◽
pp. 242-249
◽